Prof. Dr. Martin von Bergen

Head of Department of Proteomics

Speaker of Department of Metabolomics

Helmholtz Centre for Environmental Research - UFZ
Permoserstr. 15
04318 Leipzig, Germany

Tel: 0341 235 1211
Fax:0341 235 1786

Martin von Bergen, Bild

Research Interests in Environmental Health

  • Cellular response mechanisms towards environmental pollutants
  • Systems Biology based approaches using proteomic and metabolomic techniques
  • Influence of volatile organic compounds on cells of the immune system
  • Effects on ncRNA on protein expression
  • Characterisation of environmental exposure scenarios
  • Identification and characterisation of allergens from indoor-specific mould species and their impact on health
  • Development of methods for quantitative and structural proteomics and their application towards diagnostic purposes

Research Interests in Microbial Ecology and Biodegradation

  • Analysis of structure and functions of microbial communities by proteomic and metabolomic techniques
  • Mechanistic insights into anoxic degradation of environmental pollutants
  • Development of mass spectrometry based methods for quantitative and qualitative proteomics of bacteria

CV

  • since 2013: Professor at the Aalborg University, Aalborg, Denmark
  • since 2009: Speaker of Metabolomics Department
  • since 2007: “Habilitation” in molecular biology and Assistent Professor at the faculty of Biochemstry, Biology and Psychology at the University of Leipzig
  • since 2006: Head of Department of Proteomics at Helmholtz Centre for Environmental Research, Leipzig
  • 2002-2006: Senior scientist at Max Planck-Research Group for Structural Molecular Biology, Hamburg und Assistant Professor in the faculty of Biology at the University of Hamburg
  • 2001-2002: Head of Department of Proteomics in Startup company mice and more GmbH & Co KG, Hamburg
  • 1998-2001: Postdoc at Max-Planck-Research Group for Structural Molecular Biology, Hamburg
  • 1998: PhD at the faculty of Biology, University of Hamburg
  • 1995-1998: PhD studies at the Max-Planck-Research Group for Structural Molecular Biology, Hamburg
  • 1990-1995: Diploma studies in Biology at the University of Hamburg

Publications

   

2014 (18)

  • Bastida, F., Jehmlich, N., Ondoño, S., von Bergen, M., García, C., Moreno, J.L., (2014):
    Characterization of the microbial community in biological soil crusts dominated by Fulgensia desertorum (Tomin) Poelt and Squamarina cartilaginea (With.) P. James and in the underlying soil
    Soil Biol. Biochem. 76 , 70 - 79
    Volltext (URL)
  • Baumann, S., Rockstroh, M., Bartel, J., Krumsiek, J., Otto, W., Jungnickel, H., Potratz, S., Luch, A., Wilscher, E., Theis, F.J., von Bergen, M., Tomm, J.M., (2014):
    Subtoxic concentrations of benzo[a]pyrene induce metabolic changes and oxidative stress in non-activated and affect the mTOR pathway in activated Jurkat T cells
    Journal of Integrated OMICS 4 (1), 11 - 20
    Volltext (URL)
  • Bozinovski, D., Taubert, M., Kleinsteuber, S., Richnow, H.-H., von Bergen, M., Vogt, C., Seifert, J., (2014):
    Metaproteogenomic analysis of a sulfate-reducing enrichment culture reveals genomic organization of key enzymes in the m-xylene degradation pathway and metabolic activity of proteobacteria
    Syst. Appl. Microbiol. 37 (7), 488 - 501
    Volltext (URL)
  • Franck, U., Weller, A., Röder, S., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I., (2014):
    Prenatal VOC exposure and redecoration are related to wheezing in early infancy
    Environ. Int. 73 , 393 - 401
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Sack, U., Borte, M., Lehmann, I., (2014):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
    J. Allergy Clin. Immunol. 133 (2), 543 - 550.e4
    Volltext (URL)
  • Imhasly, S., Naegeli, H., Baumann, S., von Bergen, M., Luch, A., Jungnickel, H., Potratz, S., Gerspach, C., (2014):
    Metabolomic biomarkers correlating with hepatic lipidosis in dairy cows
    BMC Vet. Res. 10 , art. 122
    Volltext (PDF)
  • Jungandreas, A., Schellenberger Costa, B., Jakob, T., von Bergen, M., Baumann, S., Wilhelm, C., (2014):
    The acclimation of Phaeodactylum tricornutum to blue and red light does not influence the photosynthetic light reaction but strongly disturbs the carbon allocation pattern
    PLOS One 9 (8), e99727
    Volltext (PDF)
  • Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I., (2014):
    The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
    Clin. Immunol. 152 (1-2), 68 - 76
    Volltext (URL)
  • Jungnickel, H., Luch, A., Potratz, S., von Bergen, M., Baumann, S., Tarnow, P., (2014):
    Identification of lipidomic biomarkers for coexposure to subtoxic doses of benzo[a]pyrene and cadmium: the toxicological cascade biomarker approach
    Environ. Sci. Technol. 48 (17), 10423 - 10431
    Volltext (URL)
  • Kalkhof, S., Förster, Y., Schmidt, J., Schulz, M.C., Baumann, S., Weißflog, A., Gao, W., Hempel, U., Eckelt, U., Rammelt, S., von Bergen, M., (2014):
    Proteomics and metabolomics for in situ monitoring of wound healing
    Biomed Res. Int. 2014 , art. 934848
    Volltext (PDF)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U., (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part I. Batch cultivation with excess of carbon sources
    Syst. Appl. Microbiol. 37 (4), 277 - 286
    Volltext (PDF)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U., (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part II. Mimicking environmental conditions during cultivation in retentostats
    Syst. Appl. Microbiol. 37 (4), 287 - 295
    Volltext (PDF)
  • Mussotter, F., Haase, A., Tomm, J.M., El Ali, Z., Kerdine-Römer, S., Pallardy, M., von Bergen, M., Luch, A., (2014):
    A proteomics approach to elucidate the role of Nrf2 in primary bone-marrow-derived dendritic cells of mice upon activation by contact allergens
    Toxicol. Lett. 229 (Suppl.), S203
    Volltext (URL)
  • Oberbach, A., Schlichting, N., Neuhaus, J., Kullnick, Y., Lehmann, S., Heinrich, M., Dietrich, A., Mohr, F.-W., von Bergen-Tomm, M., Baumann, S., (2014):
    Establishing of a reliable multiple reaction monitoring-based method for the quantification of obesity associated comorbidities in serum and adipose tissue requires intensive clinical validation
    J. Proteome Res.
    Volltext (URL)
  • Rösch, C., Kohajda, T., Röder, S., von Bergen, M., Schlink, U., (2014):
    Relationship between sources and patterns of VOCs in indoor air
    Atmos. Pollut. Res. 5 (1), 129 - 137
    Volltext (URL)
  • Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J., (2014):
    Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
    Anal. Bioanal. Chem. 406 (1), 283 - 291
    Volltext (URL)
  • Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M., (2014):
    Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    J. Proteomics 98 , 59 - 64
    Volltext (URL)
  • Uhlmann, K., Gibb, S., Kalkhof, S., Arroyo-Abad, U., Schulz, C., Hoffmann, B., Stubbins, F., Carpenter, S., Beer, M., von Bergen, M., Feltens, R., (2014):
    Species determination of Culicoides biting midges via peptide profiling using matrix-assisted laser desorption ionization mass spectrometry
    Parasites Vectors 7 , 392
    Volltext (PDF)

2013 (30)

  • Baumann, S., Kalkhof, S., Hackermüller, J., Otto, W., Tomm, J.M., Wissenbach, D.K., Rolle-Kampczyk, U., von Bergen, M., (2013):
    Requirements and perspectives for integrating metabolomics with other omics data
    Current Metabolomics 1 (1), 15 - 27
    Volltext (URL)
  • Blumert, C., Kalkhof, S., Brocke-Heidrich, K., Kohajda, T., von Bergen, M., Horn, F., (2013):
    Analysis of the STAT3 interactome using in-situ biotinylation and SILAC
    J. Proteomics 94 , 370 - 386
    Volltext (URL)
  • Bodelier, P.L.E., Meima-Franke, M., Hordijk, C.A., Steenbergh, A.K., Hefting, M.E., Bodrossy, L., von Bergen, M., Seifert, J., (2013):
    Microbial minorities modulate methane consumption through niche partitioning
    ISME J. 7 , 2214 - 2228
    Volltext (URL)
  • Boll, K., Reiche, K., Kasack, K., Mörbt, N., Kretzschmar, A.K., Tomm, J.M., Verhaegh, G., Schalken, J., von Bergen, M., Horn, F., Hackermüller, J., (2013):
    MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma
    Oncogene 32 , 277 - 285
    Volltext (URL)
  • Eberlein, C., Estelmann, S., Seifert, J., von Bergen, M., Müller, M., Meckenstock, R.U., Boll, M., (2013):
    Identification and characterization of 2-naphthoyl-coenzyme A reductase, the prototype of a novel class of dearomatizing reductases
    Mol. Microbiol. 88 (5), 1032 - 1039
    Volltext (URL)
  • Ferrer, M., Ruiz, A., Lanza, F., Haange, S.-B., Oberbach, A., Till, H., Bargiela, R., Campoy, C., Segura, M.T., Richter, M., von Bergen, M., Seifert, J., Suarez, A., (2013):
    Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure
    Environ. Microbiol. 15 (1), 211 - 226
    Volltext (URL)
  • Guazzaroni, M.-E., Herbst, F.-A., Lores, I., Tamames, J., Peláez, A.I., López-Cortés, N., Alcaide, M., del Pozo, M.V., Vieites, J.M., von Bergen, M., Gallego, J.L.R., Bargiela, R., López-López, A., Pieper, D.H., Rosselló-Móra, R., Sánchez, J., Seifert, J., Ferrer, M., (2013):
    Metaproteogenomic insights beyond bacterial response to naphthalene exposure and bio-stimulation
    ISME J. 7 , 122 - 136
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen-Tomm, M., Sack, U., Borte, M., Lehmann, I., (2013):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and with low Treg numbers
    Allergy 68 (Suppl. 97), 628 - 628
    Volltext (URL)
  • Herbst, F.-A., Bahr, A., Duarte, M., Pieper, D.H., Richnow, H.-H., von Bergen, M., Seifert, J., Bombach, P., (2013):
    Elucidation of in situ polycyclic aromatic hydrocarbon degradation by functional metaproteomics (protein-SIP)
    Proteomics 13 (18-19), 2910 - 2920
    Volltext (URL)
  • Herbst, F.-A., Taubert, M., Jehmlich, N., Behr, T., Schmidt, F., von Bergen, M., Seifert, J., (2013):
    Sulfur-34S stable isotope labeling of amino acids for quantification (SULAQ34) of proteomic changes in Pseudomonas fluorescens during naphthalene degradation
    Mol. Cell. Proteomics 12 (8), 2060 - 2069
    Volltext (URL)
  • Jahn, M., Seifert, J., Hübschmann, T., von Bergen, M., Harms, H., Müller, S., (2013):
    Comparison of preservation methods for bacterial cells in cytomics and proteomics
    Journal of Integrated OMICS 3 (1), 25 - 33
    Volltext (URL)
  • Jahn, M., Seifert, J., von Bergen, M., Schmid, A., Bühler, B., Müller, S., (2013):
    Subpopulation-proteomics in prokaryotic populations
    Curr. Opin. Biotechnol. 24 (1), 79 - 87
    Volltext (URL)
  • Jechalke, S., Franchini, A., Bastida, F., Bombach, P., Rosell, M., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H., (2013):
    Analysis of structure, function, and activity of a benzene-degrading microbial community
    FEMS Microbiol.Ecol. 85 (1), 14 - 26
    Volltext (URL)
  • Kliemt, S., Lange, C., Otto, W., Hintze, V., Möller, S., von Bergen, M., Hempel, U., Kalkhof, S., (2013):
    Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells
    J. Proteome Res. 12 (1), 378 - 389
    Volltext (URL)
  • Kung, J.W., Seifert, J., von Bergen, M., Boll, M., (2013):
    Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus
    J. Bacteriol. 195 (14), 3193 - 3200
    Volltext (URL)
  • Leibeling, S., Maeß, M.B., Centler, F., Kleinsteuber, S., von Bergen, M., Thullner, M., Harms, H., Müller, R.H., (2013):
    Posttranslational oxidative modification of (R)-2-(2,4-dichlorophenoxy)propionate/α-ketoglutarate-dependent dioxygenases (RdpA) leads to improved degradation of 2,4-dichlorophenoxyacetate (2,4-D)
    Eng. Life Sci. 13 (3), 278 - 291
    Volltext (URL)
  • Markle, J.G.M., Frank, D.N., Mortin-Toth, S., Robertson, C.E., Feazel, L.M. , Rolle-Kampczyk, U., von Bergen, M., McCoy, C.D., Macpherson, A.J., Danska, J.S., (2013):
    Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
    Science 339 (6123 ), 1084 - 1088
    Volltext (URL)
  • Müller, S.A., Findeiß, S., Pernitzsch, S.R., Wissenbach, D.K., Stadler, P.F., Hofacker, I.L., von Bergen, M., Kalkhof, S., (2013):
    Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics
    J. Proteomics 86 , 27 - 42
    Volltext (URL)
  • Murugaiyan, J., Rockstroh, M., Wagner, J., Baumann, S., Schorsch, K., Trump, S., Lehmann, I., von Bergen, M., Tomm, J.M., (2013):
    Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism
    Toxicol. Appl. Pharmacol. 269 (3), 307 - 316
    Volltext (URL)
  • Murugaiyan, J., Weise, C., von Bergen, M., Roesler, U., (2013):
    Two-dimensional proteome reference map of Prototheca zopfii revealed reduced metabolism and enhanced signal transduction as adaptation to an infectious life style
    Proteomics 13 (17), 2664 - 2669
    Volltext (URL)
  • Murugesan, K., Baumann, S., Wissenbach, D.K., Kliemt, S., Kalkhof, S., Otto, W., Mögel, I., Kohajda, T., von Bergen, M., Tomm, J.M., (2013):
    Subtoxic and toxic concentrations of benzene and toluene induce Nrf-2 mediated anti-oxidative stress response and affect the central carbon metabolism in lung epithelial cells A549
    Proteomics 13 (21), 3211 - 3221
    Volltext (URL)
  • Pérez-Cobas, A.E., Gosalbes, M.J., Friedrichs, A., Knecht, H., Artacho, A., Eismann, K., Otto, W., Rojo, D., Bargiela, R., von Bergen, M., Neulinger, S.C., Däumer, C., Heinsen, F.A., Latorre, A., Barbas, C., Seifert, J., Martins dos Santos, V., Ott, S.J., Ferrer, M., Moya, A., (2013):
    Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
    Gut 62 , 1591 - 1601
    Volltext (PDF)
  • Seifert, J., Herbst, F.-A., Nielsen, P.H., Planes, F.J., Ferrer, M., von Bergen, M., (2013):
    Bioinformatic progress and applications in metaproteogenomics for bridging the gap between genomic sequences and metabolic functions in microbial communities
    Proteomics 13 (18-19), 2786 - 2804
    Volltext (URL)
  • Siegert, M., Taubert, M., Seifert, J., von Bergen-Tomm, M., Basen, M., Bastida, F., Gehre, M., Richnow, H.-H., Krüger, M., (2013):
    The nitrogen cycle in anaerobic methanotrophic mats of the Black Sea is linked to sulfate reduction and biomass decomposition
    FEMS Microbiol.Ecol. 86 (2), 231 - 245
    Volltext (URL)
  • Taubert, M., von Bergen-Tomm, M., Seifert, J., (2013):
    Limitations in detection of 15N incorporation by mass spectrometry in protein-based stable isotope probing (protein-SIP)
    Anal. Bioanal. Chem. 405 (12), 3989 - 3996
    Volltext (URL)
  • Tomm, J.M., Krause, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M., (2013):
    Pyruvate kinase and phosphopyruvate hydratase as novel IgE reactive proteins in prawn
    J. Invest. Allergol. Clin. Immunol. 23 (6), 443 - 445
    Volltext (PDF)
  • Tomm, J.M., Otto, W., Servos, U., Bertram, B., von Bergen, M., Baumann, S., (2013):
    Starvation of Jurkat T cells causes metabolic switch from glycolysis to lipolysis as revealed by comprehensive GC-qMS
    Journal of Integrated OMICS 3 (1), 70 - 74
    Volltext (URL)
  • Tomm, J.M., van Do, T., Jende, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M., (2013):
    Identification of new potential allergens from Nile perch (Lates niloticus) and Cod (Gadus morhua)
    J. Invest. Allergol. Clin. Immunol. 23 (3), 159 - 167
  • von Bergen, M., Jehmlich, N., Taubert, M., Vogt, C., Bastida, F., Herbst, F.-A., Schmidt, F., Richnow, H.-H., Seifert, J., (2013):
    Insights from quantitative metaproteomics and protein-stable isotope probing into microbial ecology
    ISME J. 7 (10), 1877 - 1885
    Volltext (URL)
  • Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I., (2013):
    Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
    Allergy 68 (2), 220 - 228
    Volltext (URL)

2012 (25)

  • Baumgarten, T., Sperling, S., Seifert, J., von Bergen, M., Steiniger, F., Wick, L.Y., Heipieper, H.J., (2012):
    Membrane vesicle formation as multiple stress response mechanism enhances cell surface hydrophobicity and biofilm formation of Pseudomonas putida DOT-T1E
    Appl. Environ. Microb. 78 (17), 6217 - 6224
    Volltext (URL)
  • Bönisch, U., Böhme, A., Kohajda, T., Mögel, I., Schütze, N., von Bergen, M., Simon, J.C., Lehmann, I., Polte, T., (2012):
    Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model
    PLoS One 7 (7), e39817
    Volltext (URL)
  • Bozinovski, D., Herrmann, S., Richnow, H.-H., von Bergen, M., Seifert, J., Vogt, C., (2012):
    Functional analysis of an anaerobic m-xylene-degrading enrichment culture using protein-based stable isotope probing
    FEMS Microbiol.Ecol. 81 (1), 134 - 144
    Volltext (URL)
  • Goettsch, C., Kliemt, S., Sinningen, K., von Bergen, M., Hofbauer, L.C., Kalkhof, S., (2012):
    Quantitative proteomics reveals novel functions of osteoclast-associated receptor in STAT signaling and cell adhesion in human endothelial cells
    J. Mol. Cell. Cardiol. 53 (6), 829 - 837
    Volltext (URL)
  • Gündel, U., Kalkhof, S., Zitzkat, D.P., von Bergen, M., Altenburger, R., Küster, E., (2012):
    Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome
    Ecotox. Environ. Safe. 76 (1), 11 - 22
    Volltext (URL)
  • Haange, S.-B., Oberbach, A., Schlichting, N., Hugenholtz, F., Smidt, H., von Bergen, M., Till, H., Seifert, J., (2012):
    Metaproteome analysis and molecular genetics of rat intestinal microbiota reveals section and localisation resolved species distribution and enzymatic functionalities
    J. Proteome Res. 11 (11), 5406 - 5417
    Volltext (URL)
  • Haas, S., Jahnke, H.-G., Moerbt, N., von Bergen, M., Aharinejad, S., Andrukhova, O., Robitzki, A.A., (2012):
    DIGE proteome analysis reveals suitability of ischemic cardiac in vitro model for studying cellular response to acute ischemia and regeneration
    PLoS One 7 (2), e31669
    Volltext (URL)
  • Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I., (2012):
    Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
    Allergy 67 (Suppl. 96), 574 - 574
    Volltext (URL)
  • Jehmlich, N., Kopinke, F.-D., Lenhard, S., Vogt, C., Herbst, F.-A., Seifert, J., Lissner, U., Völker, U., Schmidt, F., von Bergen, M., (2012):
    Sulfur-36S stable isotope labeling of amino acids for quantification (SULAQ)
    Proteomics 12 (1), 37 - 42
    Volltext (URL)
  • Kespohl, S., Kotschy-Lang, N., Tomm, J.M., von Bergen, M., Maryska, S., Brüning, T., Raulf-Heimsoth, M., (2012):
    Occupational IgE-mediated softwood allergy: characterization of the causative allergen
    Int. Arch. Allergy Immunol. 157 (2), 202 - 208
    Volltext (URL)
  • Marco-Urrea, E., Seifert, J., von Bergen, M., Adrian, L., (2012):
    Stable isotope peptide mass spectrometry to decipher amino acid metabolism in Dehalococcoides strain CBDB1
    J. Bacteriol. 194 (16), 4169 - 4177
    Volltext (URL)
  • Morris, B.E.L., Herbst, F.-A., Bastida, F., Seifert, J., von Bergen, M., Richnow, H.-H., Suflita, J.M., (2012):
    Microbial interactions during residual oil and n-fatty acid metabolism by a methanogenic consortium
    Environ. Microbiol. Rep. 4 (3), 297 - 306
    Volltext (URL)
  • Müller, S.A., van der Smissen, A., von Feilitzsch, M., Anderegg, U., Kalkhof, S., von Bergen, M., (2012):
    Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix
    J. Mater. Sci.-Mater. Med. 23 (12), 3053 - 3065
    Volltext (URL)
  • Oberbach, A., von Bergen, M., Blueher, S., Lehmann, S., Till, H., (2012):
    Combined serum proteomic and metabonomic profiling after laparoscopic sleeve gastrectomy in children and adolescents
    J. Laparoendosc. Adv. Surg. Tech. 22 (2), 184 - 188
    Volltext (URL)
  • Oberender, J., Kung, J.W., Seifert, J., von Bergen, M., Boll, M., (2012):
    Identification and characterization of a succinyl-coenzyme A (CoA):benzoate CoA transferase in Geobacter metallireducens
    J. Bacteriol. 194 (10), 2501 - 2508
    Volltext (URL)
  • Pohler, P., Lehmann, J., Veneruso, V., Tomm, J., von Bergen, M., Lambrecht, B., Kohn, B., Weingart, C., Müller, T.H., Seltsam, A., (2012):
    Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model
    Transfusion 52 (11), 2414 - 2426
    Volltext (URL)
  • Reinhold, A., Westermann, M., Seifert, J., von Bergen, M., Schubert, T., Diekert, G., (2012):
    Impact of vitamin B12 on the formation of the tetrachloroethene reductive dehalogenase in Desulfitobacterium hafniense strain Y51
    Appl. Environ. Microb. 78 (22), 8025 - 8032
    Volltext (URL)
  • Salbach, J., Kliemt, S., Rauner, M., Rachner, T.D., Goettsch, C., Kalkhof, S., von Bergen, M., Möller, S., Schnabelrauch, M., Hintze, V., Scharnweber, D., Hofbauer, L.C., (2012):
    The effect of the degree of sulfation of glycosaminoglycans on osteoclast function and signaling pathways
    Biomaterials 33 (33), 8418 - 8429
    Volltext (URL)
  • Seifert, J., Taubert, M., Jehmlich, N., Schmidt, F., Völker, U., Vogt, C., Richnow, H.H., von Bergen, M., (2012):
    Protein-based stable isotope probing (protein-SIP) in functional metaproteomics
    Mass Spectrom. Rev. 31 (6), 683 - 697
    Volltext (URL)
  • Taubert, M., Vogt, C., Wubet, T., Kleinsteuber, S., Tarkka, M.T., Harms, H., Buscot, F., Richnow, H.-H., von Bergen, M., Seifert, J., (2012):
    Protein-SIP enables time-resolved analysis of the carbon flux in a sulfate-reducing, benzene-degrading microbial consortium
    ISME J. 6 (12), 2291 - 2301
    Volltext (URL)
  • von Bergen, M., Reiche, K., Hösler, N., Rockstroh, M., Horn, F., Hackermüller, J., Tomm, J., (2012):
    A time resolved analysis of nc/mRNA and protein expression throughout Th cell activation
    Immunology 137 (Suppl. S1), 364 - 364
    Volltext (URL)
  • Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J., (2012):
    The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
    Clin. Exp. Allergy 42 (9), 1337 - 1346
    Volltext (URL)
  • Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I., (2012):
    Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
    J. Reprod. Immunol. 94 (1), 53 - 54
    Volltext (URL)
  • Wirth, H., von Bergen, M., Binder, H., (2012):
    Mining SOM expression portraits: feature selection and integrating concepts of molecular function
    BioData Mining 5 (October), art. 18
    Volltext (PDF)
  • Wirth, H., von Bergen, M., Murugaiyan, J., Roesler, U., Stokowy, T., Binder, H., (2012):
    MALDI-typing of infectious algae of the genus Prototheca using SOM portraits
    J. Microbiol. Methods 88 (1), 83 - 89
    Volltext (URL)

2011 (21)

  • Bastida, F., Jechalke, S., Bombach, P., Franchini, A.G., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H., (2011):
    Assimilation of benzene carbon through multiple trophic levels traced by different stable isotope probing methodologies
    FEMS Microbiol.Ecol. 77 (2), 357 - 369
    Volltext (URL)
  • Dautel, F., Kalkhof, S., Trump, S., Lehmann, I., Beyer, A., von Bergen, M., (2011):
    Large-scale 2-D DIGE studies - guidelines to overcome pitfalls and challenges along the experimental procedure
    Journal of Integrated OMICS 1 (1), 170 - 179
    Volltext (URL)
  • Dautel, F., Kalkhof, S., Trump, S., Michaelson, J., Beyer, A., Lehmann, I., von Bergen, M., (2011):
    DIGE-based protein expression analysis of B[a]P-exposed hepatoma cells reveals a complex stress response including alterations in oxidative stress, cell cycle control, and cytoskeleton motility at toxic and subacute concentrations
    J. Proteome Res. 10 (2), 379 - 393
    Volltext (URL)
  • Dietrich, A., Blüher, M., Jonas, S., Shang, E., Till, H., von Bergen, M., Oberbach, A., (2011):
    Metabolic effects of sleeve gastrectomy on different serum proteins
    Obes. Surg. 21 (8), 1064 - 1064
    Volltext (URL)
  • Georgieva, D., Seifert, J., Öhler, M., von Bergen, M., Spencer, P., Arni, R.K., Genov, N., Betzel, C., (2011):
    Pseudechis australis venomics: adaptation for a defense against microbial pathogens and recruitment of body transferrin
    J. Proteome Res. 10 (5), 2440 - 2464
    Volltext (URL)
  • Goodman, V., Müller, A., Gröger-Arndt, H., Schlosser, D., Jehmlich, N., Treudler, R., Lehmann, I., Simon, J.-C., von Bergen, M., (2011):
    Identification of spore specific allergen candidates from Penicillium chrysogenum
    Journal of Integrated OMICS 1 (2), 272 - 279
    Volltext (URL)
  • Jehmlich, N., Seifert, J., Taubert, M., Schmidt, F., Vogt, C., Richnow, H.H., von Bergen, M., (2011):
    Protein stable isotope probing
    In: Murrell, J.C., Whiteley, A.S., (eds.)
    Stable isotope probing and related technologies
    ASM Press, Washington, DC, p. 71 - 93
  • Kuntze, K., Kiefer, P., Baumann, S., Seifert, J., von Bergen, M., Vorholt, J.A., Boll, M., (2011):
    Enzymes involved in the anaerobic degradation of meta-substituted halobenzoates
    Mol. Microbiol. 82 (3), 758 - 769
    Volltext (URL)
  • Marco-Urrea, E., Paul, S., Khodaverdi, V., Seifert, J., von Bergen, M., Kretzschmar, U., Adrian, L., (2011):
    Identification and characterization of a Re-Citrate synthase in Dehalococcoides strain CBDB1
    J. Bacteriol. 193 (19), 5171 - 5178
    Volltext (URL)
  • Michaelson, J., Trump, S., Rudzok, S., Gräbsch, C., Madureira, D.J., Dautel, F., Mai, J., Attinger, S., Schirmer, K., von Bergen, M., Lehmann, I., Beyer, A., (2011):
    Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure
    BMC Genomics 12 , art. 502
    Volltext (PDF)
  • Mögel, I., Baumann, S., Böhme, A., Kohajda, T., von Bergen, M., Simon, J.-C., Lehmann, I., (2011):
    The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation
    Toxicology 289 (1), 28 - 37
    Volltext (URL)
  • Mörbt, N., Feltens, R., Tomm, J., Kalkhof, S., Mögel, I., Vogt, C., Lehmann, I., von Bergen, M., (2011):
    Chlorinated benzenes cause concomitantly oxidative stress and induction of apoptotic markers in lung epithelial cells (A549) at non-acute toxic concentrations
    J. Proteome Res. 10 (2), 363 - 378
    Volltext (URL)
  • Oberbach, A., Blüher, M., Wirth, H., Till, H., Kovacs, P., Kullnick, Y., Schlichting, N., Tomm, J.M., Rolle-Kampczyk, U., Murugaiyan, J., Binder, H., Dietrich, A., von Bergen, M., (2011):
    Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes
    J. Proteome Res. 10 (10), 4769 - 4788
    Volltext (URL)
  • Oberbach, A., Till, H., Dietrich, A., Shang, E., von Bergen, M., (2011):
    Integrated proteomic and lipidomic analysis of secretory phospholipase A2 and lysophosphatidylcholines metabolism following sleeve gastrectomy
    Obes. Surg. 21 (8), 1064 - 1065
    Volltext (URL)
  • Rockstroh, M., Müller, S.A., Jende, C., Kerzhner, A., von Bergen, M., Tomm, J.M., (2011):
    Cell fractionation - an important tool for compartment proteomics
    Journal of Integrated OMICS 1 (1), 135 - 143
    Volltext (URL)
  • Schmitt, J., Chen, C.M., Apfelbacher, C., Romanos, M., Lehmann, I., Herbarth, O., Schaaf, B., Kraemer, U., von Bergen, M., Wichmann, H.-E., Heinrich, J., (2011):
    Infant eczema, infant sleeping problems, and mental health at 10 years of age: the prospective birth-cohort study LISAplus
    Allergy 66 (3), 404 - 411
    Volltext (URL)
  • Schramedei, K., Mörbt, N., Pfeifer, G., Läuter, J., Rosolowski, M., Tomm, J.M., von Bergen, M., Horn, F., Brocke-Heidrich, K., (2011):
    MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4
    Oncogene 30 (6), 2975 - 2985
    Volltext (PDF)
  • Taubert, M., Baumann, S., von Bergen, M., Seifert, J., (2011):
    Exploring the limits of robust detection of incorporation of 13C by mass spectrometry in protein-based stable isotope probing (protein-SIP)
    Anal. Bioanal. Chem. 401 (6), 1975 - 1982
    Volltext (URL)
  • Taubert, M., Jehmlich, N., Vogt, C., Richnow, H.H., Schmidt, F., von Bergen, M., Seifert, J., (2011):
    Time resolved protein-based stable isotope probing (Protein-SIP) analysis allows quantification of induced proteins in substrate shift experiments
    Proteomics 11 (11), 2265 - 2274
    Volltext (URL)
  • Washietl, S., Findeiss, S., Müller, S.A., Kalkhof, S., von Bergen, M., Hofacker, I.L., Stadler, P.F., Goldmann, N., (2011):
    RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data
    RNA-Publ. RNA Soc. 17 (4), 578 - 594
    Volltext (URL)
  • Wirth, H., Löffler, M., von Bergen, M., Binder, H., (2011):
    Expression cartography of human tissues using self organizing maps
    BMC Bioinformatics 12:306
    Volltext (PDF)
 

2010

  • Strauber, H., Hubschmann, T., Jehmlich, N., Schmidt, F., von Bergen, M. , Harms, H., and Muller, S. (2010):
    NBDT (3-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-3-toluene)--a novel fluorescent dye for studying mechanisms of toluene uptake into vital bacteria
    Cytometry A 77, 113-120
    http://dx.doi.org/10.1002/cyto.a.20811
  • Selesi, D., Jehmlich, N., von Bergen, M. , Schmidt, F., Rattei, T., Tischler, P., Lueders, T., and Meckenstock, R. U. (2010):
    Combined genomic and proteomic approaches identify gene clusters involved in anaerobic 2-methylnaphthalene degradation in the sulfate-reducing enrichment culture N47
    J Bacteriol 192, 295-306
    http://dx.doi.org/10.1128/JB.00874-09
  • Schirmer, C., Klein, C., von Bergen, M. , Simon, J. C., and Saalbach, A. (2010):
    Human fibroblasts support the expansion of IL-17-producing T cells via up-regulation of IL-23 production by dendritic cells
    Blood116,1715-1725
    http://dx.doi.org/10.1182/blood-2010-01-263509
  • Ohler, M., Georgieva, D., Seifert, J., von Bergen, M. , Arni, R. K., Genov, N., and Betzel, C. (2010):
    The venomics of Bothrops alternatus is a pool of acidic proteins with predominant hemorrhagic and coagulopathic activities
    J Proteome Res 9, 2422-2437
    http://dx.doi.org/10.1021/pr901128x
  • Muller, S. A., Kohajda, T., Findeiss, S., Stadler, P. F., Washietl, S., Kellis, M., von Bergen, M. , and Kalkhof, S. (2010):
    Optimization of parameters for coverage of low molecular weight proteins
    Anal Bioanal Chem
    http://dx.doi.org/10.1007/s00216-010-4093-x
  • Leibeling, S., Schmidt, F., Jehmlich, N., von Bergen, M. , Muller, R. H., and Harms, H. (2010):
    Declining capacity of starving Delftia acidovorans MC1 to degrade phenoxypropionate herbicides correlates with oxidative modification of the initial enzyme
    Environ Sci Technol 44, 3793-3799
    http://dx.doi.org/10.1021/es903619j
  • Kung, J. W., Baumann, S., von Bergen, M. , Muller, M., Hagedoorn, P. L., Hagen, W. R., and Boll, M. (2010):
    Reversible biological Birch reduction at an extremely low redox potential
    J Am Chem Soc 132, 9850-9856
    http://dx.doi.org/10.1021/ja103448u
  • Jehmlich, N., Hubschmann, T., Gesell Salazar, M., Volker, U., Benndorf, D., Muller, S., von Bergen, M. , and Schmidt, F. (2010):
    Advanced tool for characterization of microbial cultures by combining cytomics and proteomics
    Appl Microbiol Biotechnol 88, 575-584
    http://dx.doi.org/10.1007/s00253-010-2753-6
  • Jehmlich, N., Fetzer, I., Seifert, J., Mattow, J., Vogt, C., Harms, H., Thiede, B., Richnow, H. H., von Bergen, M. , and Schmidt, F. (2010):
    Decimal place slope, a fast and precise method for quantifying 13C incorporation levels for detecting the metabolic activity of microbial species
    Mol Cell Proteomics 9, 1221-1227
    http://dx.doi.org/10.1074/mcp.M900407-MCP200
  • Georgieva, D., Redecke, L., von Bergen, M. , Genov, N., and Betzel, C. (2010):
    Interactions of ginkgolides A and B with a recombinant human prion protein
    Protein Pept Lett 17, 399-404
    http://www.benthamdirect.org/pages/b_viewarticle.php?3157685
  • Georgieva, D., Ohler, M., Seifert, J., von Bergen, M. , Arni, R. K., Genov, N., and Betzel, C. (2010):
    Snake venomic of Crotalus durissus terrificus--correlation with pharmacological activities
    J Proteome Res 9, 2302-2316
    http://dx.doi.org/10.1021/pr901042p
  • Fetzer, I., Jehmlich, N., Vogt, C., Richnow, H. H., Seifert, J., Harms, H., von Bergen, M. , and Schmidt, F. (2010):
    Calculation of partial isotope incorporation into peptides measured by mass spectrometry
    BMC Res Notes 3, 178
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913921/?tool=pubmed
  • Feltens, R., Gorner, R., Kalkhof, S., Groger-Arndt, H., and von Bergen, M. (2010):
    Discrimination of different species from the genus Drosophila by intact protein profiling using matrix-assisted laser desorption ionization mass spectrometry
    BMC Evol Biol 10, 95
    http://dx.doi.org/10.1186/1471-2148-10-95
  • Bastida, F., Rosell, M., Franchini, A. G., Seifert, J., Finsterbusch, S., Jehmlich, N., Jechalke, S., von Bergen, M. , and Richnow, H. H. (2010):
    Elucidating MTBE degradation in a mixed consortium using a multidisciplinary approach
    FEMS Microbiol Ecol 73, 370-384
    http://dx.DOI.org/10.1111/j.1574-6941.2010.00889.x
  • 2009

  • Wischgoll, S., Taubert, M., Peters, F., Jehmlich, N., von Bergen, M. , and Boll, M. (2009):
    Decarboxylating and nondecarboxylating glutaryl-coenzyme A dehydrogenases in the aromatic metabolism of obligately anaerobic bacteria
    J Bacteriol 191, 4401-4409
    http://dx.doi.org/10.1128/JB.00205-09
  • Schleinitz, K. M., Schmeling, S., Jehmlich, N., von Bergen, M. , Harms, H., Kleinsteuber, S., Vogt, C., and Fuchs, G. (2009):
    Phenol degradation in the strictly anaerobic iron-reducing bacterium Geobacter metallireducens GS-15
    Appl Environ Microbiol 75, 3912-3919
    http://dx.doi.org/10.1128/AEM.01525-08
  • Risch, M., Georgieva, D., von Bergen, M. , Jehmlich, N., Genov, N., Arni, R. K., and Betzel, C. (2009):
    Snake venomics of the Siamese Russell's viper (Daboia russelli siamensis) -- relation to pharmacological activities
    J Proteomics 72, 256-269
    http://dx.doi.org/10.1016/j.jprot.2009.01.006
  • Rehders, D., Claasen, B., Redecke, L., Buschke, A., Reibe, C., Jehmlich, N., von Bergen, M. , Betzel, C., and Meyer, B. (2009):
    Peptide NMHRYPNQ of the cellular prion protein (PrP(C)) inhibits aggregation and is a potential key for understanding prion-prion interactions
    J Mol Biol 392, 198-207
    http://dx.doi.org/ 10.1016/j.jmb.2009.07.014
  • Morbt, N., Mogel, I., Kalkhof, S., Feltens, R., Roder-Stolinski, C., Zheng, J., Vogt, C., Lehmann, I., and von Bergen, M. (2009):
    Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism
    Proteomics 9, 4920-4933
    http://dx.doi.org/10.1002/pmic.200800836
  • Junghanns, C., Pecyna, M. J., Bohm, D., Jehmlich, N., Martin, C., von Bergen, M. , Schauer, F., Hofrichter, M., and Schlosser, D. (2009):
    Biochemical and molecular genetic characterisation of a novel laccase produced by the aquatic ascomycete Phoma sp. UHH 5-1-03
    Appl Microbiol Biotechnol 84, 1095-1105
    http://dx.doi.org/10.1007/s00253-009-2028-2
  • Jehmlich, N., Schmidt, F., Taubert, M., Seifert, J., von Bergen, M. , Richnow, H. H., and Vogt, C. (2009):
    Comparison of methods for simultaneous identification of bacterial species and determination of metabolic activity by protein-based stable isotope probing (Protein-SIP) experiments
    Rapid Commun Mass Spectrom 23, 1871-1878
    http://dx.doi.org/10.1002/rcm.4084
  • Heine, F., Stahl, F., Strauber, H., Wiacek, C., Benndorf, D., Repenning, C., Schmidt, F., Scheper, T., von Bergen, M. , Harms, H., and Muller, S. (2009):
    Prediction of flocculation ability of brewing yeast inoculates by flow cytometry, proteome analysis, and mRNA profiling
    Cytometry A 75, 140-147
    http://dx.doi.org/10.1002/cyto.a.20661
  • Benndorf, D., Vogt, C., Jehmlich, N., Schmidt, Y., Thomas, H., Woffendin, G., Shevchenko, A., Richnow, H. H., and von Bergen, M. (2009):
    Improving protein extraction and separation methods for investigating the metaproteome of anaerobic benzene communities within sediments
    Biodegradation 20, 737-750
    http://dx.doi.org/10.1007/s10532-009-9261-3
  • 2008

  • Thiele, B., Rieder, O., Jehmlich, N., von Bergen, M. , Muller, M., and Boll, M. (2008):
    Aromatizing cyclohexa-1,5-diene-1-carbonyl-coenzyme A oxidase. Characterization and its role in anaerobic aromatic metabolism
    J Biol Chem 283, 20713-20721
    http://dx.doi.org/10.1074/jbc.M802841200
  • Roder-Stolinski, C., Fischader, G., Oostingh, G. J., Feltens, R., Kohse, F., von Bergen, M. , Morbt, N., Eder, K., Duschl, A., and Lehmann, I. (2008):
    Styrene induces an inflammatory response in human lung epithelial cells via oxidative stress and NF-kappaB activation
    Toxicol Appl Pharmacol 231, 241-247
    http://dx.doi.org/10.1016/j.taap.2008.04.010
  • Johannes, J., Bluschke, A., Jehmlich, N., von Bergen, M. , and Boll, M. (2008):
    Purification and characterization of active-site components of the putative p-cresol methylhydroxylase membrane complex from Geobacter metallireducens
    J Bacteriol 190, 6493-6500
    http://dx.doi.org/10.1128/JB.00790-08
  • Jehmlich, N., Schmidt, F., von Bergen, M. , Richnow, H. H., and Vogt, C. (2008):
    Protein-based stable isotope probing (Protein-SIP) reveals active species within anoxic mixed cultures
    ISME J 2, 1122-1133
    http://dx.doi.org/10.1038/ismej.2008.64
  • Jehmlich, N., Schmidt, F., Hartwich, M., von Bergen, M. , Richnow, H. H., and Vogt, C. (2008):
    Incorporation of carbon and nitrogen atoms into proteins measured by protein-based stable isotope probing (Protein-SIP)
    Rapid Commun Mass Spectrom 22, 2889-2897
    http://dx.doi.org/10.1002/rcm.3684
  • Jeganathan, S., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2008):
    The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments
    Biochemistry 47, 10526-10539
    http://dx.doi.org/10.1021/bi800783d
  • Hehemann, J. H., Redecke, L., Murugaiyan, J., von Bergen, M. , Betzel, C., and Saborowski, R. (2008):
    Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus
    Biochem Biophys Res Commun 370, 566-571
    http://dx.doi.org/10.1016/j.bbrc.2008.03.128
  • Georgieva, D., Risch, M., Kardas, A., Buck, F., von Bergen, M. , and Betzel, C. (2008):
    Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis
    J Proteome Res 7, 866-886
    http://dx.doi.org/10.1021/pr070376c
  • Benndorf, D., Muller, A., Bock, K., Manuwald, O., Herbarth, O., and von Bergen, M. (2008):
    Identification of spore allergens from the indoor mould Aspergillus versicolor
    Allergy 63, 454-460
    http://dx.doi.org/10.1111/j.1398-9995.2007.01603.x
  • Andronesi, O. C., von Bergen, M. , Biernat, J., Seidel, K., Griesinger, C., Mandelkow, E., and Baldus, M. (2008):
    Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy
    J Am Chem Soc 130, 5922-5928
    http://dx.doi.org/10.1021/ja7100517
  • 2007

  • Santos, P. M., Roma, V., Benndorf, D., von Bergen, M. , Harms, H., and Sa-Correia, I. (2007):
    Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 revealed by quantitative proteomics
    OMICS 11, 233-251
    http://dx.doi.org/10.1089/omi.2007.0009
  • Redecke, L., von Bergen, M. , Clos, J., Konarev, P. V., Svergun, D. I., Fittschen, U. E., Broekaert, J. A., Bruns, O., Georgieva, D., Mandelkow, E., Genov, N., and Betzel, C. (2007):
    Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro
    J Struct Biol 157, 308-320
    http://dx.doi.org/10.1016/j.jsb.2006.06.013
  • Mukrasch, M. D., von Bergen, M. , Biernat, J., Fischer, D., Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2007):
    The "jaws" of the tau-microtubule interaction
    J Biol Chem 282, 12230-12239
    http://dx.doi.org/10.1074/jbc.M607159200
  • Martin, C., Pecyna, M., Kellner, H., Jehmlich, N., Junghanns, C., Benndorf, D., von Bergen, M. , and Schlosser, D. (2007):
    Purification and biochemical characterization of a laccase from the aquatic fungus Myrioconium sp. UHH 1-13-18-4 and molecular analysis of the laccase-encoding gene
    Appl Microbiol Biotechnol 77, 613-624
    http://dx.doi.org/10.1007/s00253-007-1207-2
  • Mandelkow, E., von Bergen, M. , Biernat, J., and Mandelkow, E. M. (2007):
    Structural principles of tau and the paired helical filaments of Alzheimer's disease
    Brain Pathol 17, 83-90
    http://dx.doi.org/10.1111/j.1750-3639.2007.00053.x
  • Gundel, U., Benndorf, D., von Bergen, M. , Altenburger, R., and Kuster, E. (2007):
    Vitellogenin cleavage products as indicators for toxic stress in zebra fish embryos: a proteomic approach
    Proteomics 7, 4541-4554
    http://dx.doi.org/10.1002/pmic.200700381
  • Fischer, D., Mukrasch, M. D., von Bergen, M. , Klos-Witkowska, A., Biernat, J., Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2007):
    Structural and microtubule binding properties of tau mutants of frontotemporal dementias
    Biochemistry 46, 2574-2582
    http://dx.doi.org/10.1021/bi061318s
  • Benndorf, D., Balcke, G. U., Harms, H., and von Bergen, M. (2007):
    Functional metaproteome analysis of protein extracts from contaminated soil and groundwater
    ISME J 1, 224-234
    http://dx.doi.org/10.1038/ismej.2007.39
  • 2006

  • von Bergen, M. , Barghorn, S., Muller, S. A., Pickhardt, M., Biernat, J., Mandelkow, E. M., Davies, P., Aebi, U., and Mandelkow, E. (2006):
    The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis
    Biochemistry 45, 6446-6457
    http://dx.doi.org/10.1021/bi052530j
  • von Bergen, M. , Barghorn, S., Jeganathan, S., Mandelkow, E. M., and Mandelkow, E. (2006):
    Spectroscopic approaches to the conformation of tau protein in solution and in paired helical filaments
    Neurodegener Dis 3, 197-206
    http://dx.doi.org/10.1159/000095257
  • Khlistunova, I., Biernat, J., Wang, Y., Pickhardt, M., von Bergen, M. , Gazova, Z., Mandelkow, E., and Mandelkow, E. M. (2006):
    Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs
    J Biol Chem 281, 1205-1214
    http://dx.doi.org/10.1074/jbc.M507753200
  • Jeganathan, S., von Bergen, M. , Brutlach, H., Steinhoff, H. J., and Mandelkow, E. (2006):
    Global hairpin folding of tau in solution
    Biochemistry 45, 2283-2293
    http://dx.doi.org/10.1021/bi0521543
  • Georgieva, D., Schwark, D., von Bergen, M. , Redecke, L., Genov, N., and Betzel, C. (2006):
    Interactions of recombinant prions with compounds of therapeutical significance
    Biochem Biophys Res Commun 344, 463-470
    http://dx.doi.org/10.1016/j.bbrc.2006.03.135
  • von Bergen, M. , Li, L., and Mandelkow, E. (2005):
    Intrinsic fluorescent detection of tau conformation and aggregation
    Methods Mol Biol 299, 175-184
    http://www.mpasmb-hamburg.mpg.de/mandelkow2/publikationen/index.html
  • 1998-2005

  • von Bergen, M. , Barghorn, S., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2005):
    Tau aggregation is driven by a transition from random coil to beta sheet structure
    Biochim Biophys Acta 1739, 158-166
    http://dx.doi.org/10.1016/j.bbadis.2004.09.010
  • Pickhardt, M., von Bergen, M. , Gazova, Z., Hascher, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2005):
    Screening for inhibitors of tau polymerization
    Curr Alzheimer Res 2, 219-226
    http://dx.DOI.ORG/10.2174/1567205053585891
  • Pickhardt, M., Gazova, Z., von Bergen, M. , Khlistunova, I., Wang, Y., Hascher, A., Mandelkow, E. M., Biernat, J., and Mandelkow, E. (2005):
    Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells
    J Biol Chem 280, 3628-3635
    http://dx.doi.org/10.1074/jbc.M410984200
  • Mukrasch, M. D., Biernat, J., von Bergen, M. , Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2005):
    Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions
    J Biol Chem 280, 24978-24986
    http://dx.doi.org/10.1074/jbc.M501565200
  • Li, L., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2002):
    Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis
    J Biol Chem 277, 41390-41400
    http://dx.doi.org/10.1074/jbc.M206334200
  • von Bergen, M. , Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001):
    Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
    J Biol Chem 276, 48165-48174
    http://dx.doi.org/10.1074/jbc.M105196200
  • von Bergen, M. , Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. (2000):
    Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
    Proc Natl Acad Sci U S A 97, 5129-5134
    http://www.pnas.org/content/97/10/5129.abstract
  • Friedhoff, P., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2000):
    Structure of tau protein and assembly into paired helical filaments
    Biochim Biophys Acta 1502, 122-132
    http://dx.doi.org/10.1016/S0925-4439(00)00038-7
  • Barghorn, S., Zheng-Fischhofer, Q., Ackmann, M., Biernat, J., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2000):
    Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
    Biochemistry 39, 11714-11721
    http://dx.doi.org/bi000850r
  • Schneider, A., Biernat, J., von Bergen, M. , Mandelkow, E., and Mandelkow, E. M. (1999):
    Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
    Biochemistry 38, 3549-3558
    http://www.ncbi.nlm.nih.gov/pubmed/10995239
  • Friedhoff, P., von Bergen, M. , Mandelkow, E. M., Davies, P., and Mandelkow, E. (1998):
    A nucleated assembly mechanism of Alzheimer paired helical filaments
    Proc Natl Acad Sci U S A 95, 15712-15717
    http://dx.doi.org/10.1016/S0925-4439(00)00038-7

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aktuelle Publikationen

2014 (16)

  • Bastida, F., Jehmlich, N., Ondoño, S., von Bergen, M., García, C., Moreno, J.L. (2014):
    Characterization of the microbial community in biological soil crusts dominated by Fulgensia desertorum (Tomin) Poelt and Squamarina cartilaginea (With.) P. James and in the underlying soil
    Soil Biol. Biochem. 76 , 70 - 79
    Volltext (URL)
  • Bozinovski, D., Taubert, M., Kleinsteuber, S., Richnow, H.-H., von Bergen, M., Vogt, C., Seifert, J. (2014):
    Metaproteogenomic analysis of a sulfate-reducing enrichment culture reveals genomic organization of key enzymes in the m-xylene degradation pathway and metabolic activity of proteobacteria
    Syst. Appl. Microbiol. 37 (7), 488 - 501
    Volltext (URL)
  • Franck, U., Weller, A., Röder, S., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I. (2014):
    Prenatal VOC exposure and redecoration are related to wheezing in early infancy
    Environ. Int. 73 , 393 - 401
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Sack, U., Borte, M., Lehmann, I. (2014):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
    J. Allergy Clin. Immunol. 133 (2), 543 - 550.e4
    Volltext (URL)
  • Imhasly, S., Naegeli, H., Baumann, S., von Bergen, M., Luch, A., Jungnickel, H., Potratz, S., Gerspach, C. (2014):
    Metabolomic biomarkers correlating with hepatic lipidosis in dairy cows
    BMC Vet. Res. 10 , art. 122
    Volltext (PDF)
  • Jungandreas, A., Schellenberger Costa, B., Jakob, T., von Bergen, M., Baumann, S., Wilhelm, C. (2014):
    The acclimation of Phaeodactylum tricornutum to blue and red light does not influence the photosynthetic light reaction but strongly disturbs the carbon allocation pattern
    PLOS One 9 (8), e99727
    Volltext (PDF)
  • Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I. (2014):
    The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
    Clin. Immunol. 152 (1-2), 68 - 76
    Volltext (URL)
  • Jungnickel, H., Luch, A., Potratz, S., von Bergen, M., Baumann, S., Tarnow, P. (2014):
    Identification of lipidomic biomarkers for coexposure to subtoxic doses of benzo[a]pyrene and cadmium: the toxicological cascade biomarker approach
    Environ. Sci. Technol. 48 (17), 10423 - 10431
    Volltext (URL)
  • Kalkhof, S., Förster, Y., Schmidt, J., Schulz, M.C., Baumann, S., Weißflog, A., Gao, W., Hempel, U., Eckelt, U., Rammelt, S., von Bergen, M. (2014):
    Proteomics and metabolomics for in situ monitoring of wound healing
    Biomed Res. Int. 2014 , art. 934848
    Volltext (PDF)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U. (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part I. Batch cultivation with excess of carbon sources
    Syst. Appl. Microbiol. 37 (4), 277 - 286
    Volltext (PDF)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U. (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part II. Mimicking environmental conditions during cultivation in retentostats
    Syst. Appl. Microbiol. 37 (4), 287 - 295
    Volltext (PDF)
  • Mussotter, F., Haase, A., Tomm, J.M., El Ali, Z., Kerdine-Römer, S., Pallardy, M., von Bergen, M., Luch, A. (2014):
    A proteomics approach to elucidate the role of Nrf2 in primary bone-marrow-derived dendritic cells of mice upon activation by contact allergens
    Toxicol. Lett. 229 (Suppl.), S203
    Volltext (URL)
  • Rösch, C., Kohajda, T., Röder, S., von Bergen, M., Schlink, U. (2014):
    Relationship between sources and patterns of VOCs in indoor air
    Atmos. Pollut. Res. 5 (1), 129 - 137
    Volltext (URL)
  • Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J. (2014):
    Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
    Anal. Bioanal. Chem. 406 (1), 283 - 291
    Volltext (URL)
  • Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M. (2014):
    Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    J. Proteomics 98 , 59 - 64
    Volltext (URL)
  • Uhlmann, K., Gibb, S., Kalkhof, S., Arroyo-Abad, U., Schulz, C., Hoffmann, B., Stubbins, F., Carpenter, S., Beer, M., von Bergen, M., Feltens, R. (2014):
    Species determination of Culicoides biting midges via peptide profiling using matrix-assisted laser desorption ionization mass spectrometry
    Parasites Vectors 7 , 392
    Volltext (PDF)

2013 (27)

  • Blumert, C., Kalkhof, S., Brocke-Heidrich, K., Kohajda, T., von Bergen, M., Horn, F. (2013):
    Analysis of the STAT3 interactome using in-situ biotinylation and SILAC
    J. Proteomics 94 , 370 - 386
    Volltext (URL)
  • Bodelier, P.L.E., Meima-Franke, M., Hordijk, C.A., Steenbergh, A.K., Hefting, M.E., Bodrossy, L., von Bergen, M., Seifert, J. (2013):
    Microbial minorities modulate methane consumption through niche partitioning
    ISME J. 7 , 2214 - 2228
    Volltext (URL)
  • Boll, K., Reiche, K., Kasack, K., Mörbt, N., Kretzschmar, A.K., Tomm, J.M., Verhaegh, G., Schalken, J., von Bergen, M., Horn, F., Hackermüller, J. (2013):
    MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma
    Oncogene 32 , 277 - 285
    Volltext (URL)
  • Eberlein, C., Estelmann, S., Seifert, J., von Bergen, M., Müller, M., Meckenstock, R.U., Boll, M. (2013):
    Identification and characterization of 2-naphthoyl-coenzyme A reductase, the prototype of a novel class of dearomatizing reductases
    Mol. Microbiol. 88 (5), 1032 - 1039
    Volltext (URL)
  • Ferrer, M., Ruiz, A., Lanza, F., Haange, S.-B., Oberbach, A., Till, H., Bargiela, R., Campoy, C., Segura, M.T., Richter, M., von Bergen, M., Seifert, J., Suarez, A. (2013):
    Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure
    Environ. Microbiol. 15 (1), 211 - 226
    Volltext (URL)
  • Guazzaroni, M.-E., Herbst, F.-A., Lores, I., Tamames, J., Peláez, A.I., López-Cortés, N., Alcaide, M., del Pozo, M.V., Vieites, J.M., von Bergen, M., Gallego, J.L.R., Bargiela, R., López-López, A., Pieper, D.H., Rosselló-Móra, R., Sánchez, J., Seifert, J., Ferrer, M. (2013):
    Metaproteogenomic insights beyond bacterial response to naphthalene exposure and bio-stimulation
    ISME J. 7 , 122 - 136
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen-Tomm, M., Sack, U., Borte, M., Lehmann, I. (2013):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and with low Treg numbers
    Allergy 68 (Suppl. 97), 628 - 628
    Volltext (URL)
  • Herbst, F.-A., Bahr, A., Duarte, M., Pieper, D.H., Richnow, H.-H., von Bergen, M., Seifert, J., Bombach, P. (2013):
    Elucidation of in situ polycyclic aromatic hydrocarbon degradation by functional metaproteomics (protein-SIP)
    Proteomics 13 (18-19), 2910 - 2920
    Volltext (URL)
  • Herbst, F.-A., Taubert, M., Jehmlich, N., Behr, T., Schmidt, F., von Bergen, M., Seifert, J. (2013):
    Sulfur-34S stable isotope labeling of amino acids for quantification (SULAQ34) of proteomic changes in Pseudomonas fluorescens during naphthalene degradation
    Mol. Cell. Proteomics 12 (8), 2060 - 2069
    Volltext (URL)
  • Jahn, M., Seifert, J., von Bergen, M., Schmid, A., Bühler, B., Müller, S. (2013):
    Subpopulation-proteomics in prokaryotic populations
    Curr. Opin. Biotechnol. 24 (1), 79 - 87
    Volltext (URL)
  • Jechalke, S., Franchini, A., Bastida, F., Bombach, P., Rosell, M., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H. (2013):
    Analysis of structure, function, and activity of a benzene-degrading microbial community
    FEMS Microbiol.Ecol. 85 (1), 14 - 26
    Volltext (URL)
  • Kliemt, S., Lange, C., Otto, W., Hintze, V., Möller, S., von Bergen, M., Hempel, U., Kalkhof, S. (2013):
    Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells
    J. Proteome Res. 12 (1), 378 - 389
    Volltext (URL)
  • Kung, J.W., Seifert, J., von Bergen, M., Boll, M. (2013):
    Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus
    J. Bacteriol. 195 (14), 3193 - 3200
    Volltext (URL)
  • Leibeling, S., Maeß, M.B., Centler, F., Kleinsteuber, S., von Bergen, M., Thullner, M., Harms, H., Müller, R.H. (2013):
    Posttranslational oxidative modification of (R)-2-(2,4-dichlorophenoxy)propionate/α-ketoglutarate-dependent dioxygenases (RdpA) leads to improved degradation of 2,4-dichlorophenoxyacetate (2,4-D)
    Eng. Life Sci. 13 (3), 278 - 291
    Volltext (URL)
  • Markle, J.G.M., Frank, D.N., Mortin-Toth, S., Robertson, C.E., Feazel, L.M. , Rolle-Kampczyk, U., von Bergen, M., McCoy, C.D., Macpherson, A.J., Danska, J.S. (2013):
    Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
    Science 339 (6123 ), 1084 - 1088
    Volltext (URL)
  • Müller, S.A., Findeiß, S., Pernitzsch, S.R., Wissenbach, D.K., Stadler, P.F., Hofacker, I.L., von Bergen, M., Kalkhof, S. (2013):
    Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics
    J. Proteomics 86 , 27 - 42
    Volltext (URL)
  • Murugaiyan, J., Rockstroh, M., Wagner, J., Baumann, S., Schorsch, K., Trump, S., Lehmann, I., von Bergen, M., Tomm, J.M. (2013):
    Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism
    Toxicol. Appl. Pharmacol. 269 (3), 307 - 316
    Volltext (URL)
  • Murugaiyan, J., Weise, C., von Bergen, M., Roesler, U. (2013):
    Two-dimensional proteome reference map of Prototheca zopfii revealed reduced metabolism and enhanced signal transduction as adaptation to an infectious life style
    Proteomics 13 (17), 2664 - 2669
    Volltext (URL)
  • Murugesan, K., Baumann, S., Wissenbach, D.K., Kliemt, S., Kalkhof, S., Otto, W., Mögel, I., Kohajda, T., von Bergen, M., Tomm, J.M. (2013):
    Subtoxic and toxic concentrations of benzene and toluene induce Nrf-2 mediated anti-oxidative stress response and affect the central carbon metabolism in lung epithelial cells A549
    Proteomics 13 (21), 3211 - 3221
    Volltext (URL)
  • Pérez-Cobas, A.E., Gosalbes, M.J., Friedrichs, A., Knecht, H., Artacho, A., Eismann, K., Otto, W., Rojo, D., Bargiela, R., von Bergen, M., Neulinger, S.C., Däumer, C., Heinsen, F.A., Latorre, A., Barbas, C., Seifert, J., Martins dos Santos, V., Ott, S.J., Ferrer, M., Moya, A. (2013):
    Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
    Gut 62 , 1591 - 1601
    Volltext (PDF)
  • Seifert, J., Herbst, F.-A., Nielsen, P.H., Planes, F.J., Ferrer, M., von Bergen, M. (2013):
    Bioinformatic progress and applications in metaproteogenomics for bridging the gap between genomic sequences and metabolic functions in microbial communities
    Proteomics 13 (18-19), 2786 - 2804
    Volltext (URL)
  • Siegert, M., Taubert, M., Seifert, J., von Bergen-Tomm, M., Basen, M., Bastida, F., Gehre, M., Richnow, H.-H., Krüger, M. (2013):
    The nitrogen cycle in anaerobic methanotrophic mats of the Black Sea is linked to sulfate reduction and biomass decomposition
    FEMS Microbiol.Ecol. 86 (2), 231 - 245
    Volltext (URL)
  • Taubert, M., von Bergen-Tomm, M., Seifert, J. (2013):
    Limitations in detection of 15N incorporation by mass spectrometry in protein-based stable isotope probing (protein-SIP)
    Anal. Bioanal. Chem. 405 (12), 3989 - 3996
    Volltext (URL)
  • Tomm, J.M., Krause, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M. (2013):
    Pyruvate kinase and phosphopyruvate hydratase as novel IgE reactive proteins in prawn
    J. Invest. Allergol. Clin. Immunol. 23 (6), 443 - 445
    Volltext (PDF)
  • Tomm, J.M., van Do, T., Jende, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M. (2013):
    Identification of new potential allergens from Nile perch (Lates niloticus) and Cod (Gadus morhua)
    J. Invest. Allergol. Clin. Immunol. 23 (3), 159 - 167
  • von Bergen, M., Jehmlich, N., Taubert, M., Vogt, C., Bastida, F., Herbst, F.-A., Schmidt, F., Richnow, H.-H., Seifert, J. (2013):
    Insights from quantitative metaproteomics and protein-stable isotope probing into microbial ecology
    ISME J. 7 (10), 1877 - 1885
    Volltext (URL)
  • Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I. (2013):
    Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
    Allergy 68 (2), 220 - 228
    Volltext (URL)

2012 (25)

  • Baumgarten, T., Sperling, S., Seifert, J., von Bergen, M., Steiniger, F., Wick, L.Y., Heipieper, H.J. (2012):
    Membrane vesicle formation as multiple stress response mechanism enhances cell surface hydrophobicity and biofilm formation of Pseudomonas putida DOT-T1E
    Appl. Environ. Microb. 78 (17), 6217 - 6224
    Volltext (URL)
  • Bönisch, U., Böhme, A., Kohajda, T., Mögel, I., Schütze, N., von Bergen, M., Simon, J.C., Lehmann, I., Polte, T. (2012):
    Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model
    PLoS One 7 (7), e39817
    Volltext (URL)
  • Bozinovski, D., Herrmann, S., Richnow, H.-H., von Bergen, M., Seifert, J., Vogt, C. (2012):
    Functional analysis of an anaerobic m-xylene-degrading enrichment culture using protein-based stable isotope probing
    FEMS Microbiol.Ecol. 81 (1), 134 - 144
    Volltext (URL)
  • Goettsch, C., Kliemt, S., Sinningen, K., von Bergen, M., Hofbauer, L.C., Kalkhof, S. (2012):
    Quantitative proteomics reveals novel functions of osteoclast-associated receptor in STAT signaling and cell adhesion in human endothelial cells
    J. Mol. Cell. Cardiol. 53 (6), 829 - 837
    Volltext (URL)
  • Gündel, U., Kalkhof, S., Zitzkat, D.P., von Bergen, M., Altenburger, R., Küster, E. (2012):
    Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome
    Ecotox. Environ. Safe. 76 (1), 11 - 22
    Volltext (URL)
  • Haange, S.-B., Oberbach, A., Schlichting, N., Hugenholtz, F., Smidt, H., von Bergen, M., Till, H., Seifert, J. (2012):
    Metaproteome analysis and molecular genetics of rat intestinal microbiota reveals section and localisation resolved species distribution and enzymatic functionalities
    J. Proteome Res. 11 (11), 5406 - 5417
    Volltext (URL)
  • Haas, S., Jahnke, H.-G., Moerbt, N., von Bergen, M., Aharinejad, S., Andrukhova, O., Robitzki, A.A. (2012):
    DIGE proteome analysis reveals suitability of ischemic cardiac in vitro model for studying cellular response to acute ischemia and regeneration
    PLoS One 7 (2), e31669
    Volltext (URL)
  • Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I. (2012):
    Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
    Allergy 67 (Suppl. 96), 574 - 574
    Volltext (URL)
  • Jehmlich, N., Kopinke, F.-D., Lenhard, S., Vogt, C., Herbst, F.-A., Seifert, J., Lissner, U., Völker, U., Schmidt, F., von Bergen, M. (2012):
    Sulfur-36S stable isotope labeling of amino acids for quantification (SULAQ)
    Proteomics 12 (1), 37 - 42
    Volltext (URL)
  • Kespohl, S., Kotschy-Lang, N., Tomm, J.M., von Bergen, M., Maryska, S., Brüning, T., Raulf-Heimsoth, M. (2012):
    Occupational IgE-mediated softwood allergy: characterization of the causative allergen
    Int. Arch. Allergy Immunol. 157 (2), 202 - 208
    Volltext (URL)
  • Marco-Urrea, E., Seifert, J., von Bergen, M., Adrian, L. (2012):
    Stable isotope peptide mass spectrometry to decipher amino acid metabolism in Dehalococcoides strain CBDB1
    J. Bacteriol. 194 (16), 4169 - 4177
    Volltext (URL)
  • Morris, B.E.L., Herbst, F.-A., Bastida, F., Seifert, J., von Bergen, M., Richnow, H.-H., Suflita, J.M. (2012):
    Microbial interactions during residual oil and n-fatty acid metabolism by a methanogenic consortium
    Environ. Microbiol. Rep. 4 (3), 297 - 306
    Volltext (URL)
  • Müller, S.A., van der Smissen, A., von Feilitzsch, M., Anderegg, U., Kalkhof, S., von Bergen, M. (2012):
    Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix
    J. Mater. Sci.-Mater. Med. 23 (12), 3053 - 3065
    Volltext (URL)
  • Oberbach, A., von Bergen, M., Blueher, S., Lehmann, S., Till, H. (2012):
    Combined serum proteomic and metabonomic profiling after laparoscopic sleeve gastrectomy in children and adolescents
    J. Laparoendosc. Adv. Surg. Tech. 22 (2), 184 - 188
    Volltext (URL)
  • Oberender, J., Kung, J.W., Seifert, J., von Bergen, M., Boll, M. (2012):
    Identification and characterization of a succinyl-coenzyme A (CoA):benzoate CoA transferase in Geobacter metallireducens
    J. Bacteriol. 194 (10), 2501 - 2508
    Volltext (URL)
  • Pohler, P., Lehmann, J., Veneruso, V., Tomm, J., von Bergen, M., Lambrecht, B., Kohn, B., Weingart, C., Müller, T.H., Seltsam, A. (2012):
    Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model
    Transfusion 52 (11), 2414 - 2426
    Volltext (URL)
  • Reinhold, A., Westermann, M., Seifert, J., von Bergen, M., Schubert, T., Diekert, G. (2012):
    Impact of vitamin B12 on the formation of the tetrachloroethene reductive dehalogenase in Desulfitobacterium hafniense strain Y51
    Appl. Environ. Microb. 78 (22), 8025 - 8032
    Volltext (URL)
  • Salbach, J., Kliemt, S., Rauner, M., Rachner, T.D., Goettsch, C., Kalkhof, S., von Bergen, M., Möller, S., Schnabelrauch, M., Hintze, V., Scharnweber, D., Hofbauer, L.C. (2012):
    The effect of the degree of sulfation of glycosaminoglycans on osteoclast function and signaling pathways
    Biomaterials 33 (33), 8418 - 8429
    Volltext (URL)
  • Seifert, J., Taubert, M., Jehmlich, N., Schmidt, F., Völker, U., Vogt, C., Richnow, H.H., von Bergen, M. (2012):
    Protein-based stable isotope probing (protein-SIP) in functional metaproteomics
    Mass Spectrom. Rev. 31 (6), 683 - 697
    Volltext (URL)
  • Taubert, M., Vogt, C., Wubet, T., Kleinsteuber, S., Tarkka, M.T., Harms, H., Buscot, F., Richnow, H.-H., von Bergen, M., Seifert, J. (2012):
    Protein-SIP enables time-resolved analysis of the carbon flux in a sulfate-reducing, benzene-degrading microbial consortium
    ISME J. 6 (12), 2291 - 2301
    Volltext (URL)
  • von Bergen, M., Reiche, K., Hösler, N., Rockstroh, M., Horn, F., Hackermüller, J., Tomm, J. (2012):
    A time resolved analysis of nc/mRNA and protein expression throughout Th cell activation
    Immunology 137 (Suppl. S1), 364 - 364
    Volltext (URL)
  • Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J. (2012):
    The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
    Clin. Exp. Allergy 42 (9), 1337 - 1346
    Volltext (URL)
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