Prof. Dr. Martin von Bergen

Head of Department of Proteomics

Speaker of Department of Metabolomics

Helmholtz Centre for Environmental Research - UFZ
Permoserstr. 15
04318 Leipzig, Germany

Tel: 0341 235 1211
Fax:0341 235 1786


Martin von Bergen, Bild

Research Interests in Environmental Health

  • Cellular response mechanisms towards environmental pollutants
  • Systems Biology based approaches using proteomic and metabolomic techniques
  • Influence of volatile organic compounds on cells of the immune system
  • Effects on ncRNA on protein expression
  • Characterisation of environmental exposure scenarios
  • Identification and characterisation of allergens from indoor-specific mould species and their impact on health
  • Development of methods for quantitative and structural proteomics and their application towards diagnostic purposes

Research Interests in Microbial Ecology and Biodegradation

  • Analysis of structure and functions of microbial communities by proteomic and metabolomic techniques
  • Mechanistic insights into anoxic degradation of environmental pollutants
  • Development of mass spectrometry based methods for quantitative and qualitative proteomics of bacteria

CV

  • since 2013: Professor at the Aalborg University, Aalborg, Denmark
  • since 2009: Speaker of Metabolomics Department
  • since 2007: “Habilitation” in molecular biology and Assistent Professor at the faculty of Biochemstry, Biology and Psychology at the University of Leipzig
  • since 2006: Head of Department of Proteomics at Helmholtz Centre for Environmental Research, Leipzig
  • 2002-2006: Senior scientist at Max Planck-Research Group for Structural Molecular Biology, Hamburg und Assistant Professor in the faculty of Biology at the University of Hamburg
  • 2001-2002: Head of Department of Proteomics in Startup company mice and more GmbH & Co KG, Hamburg
  • 1998-2001: Postdoc at Max-Planck-Research Group for Structural Molecular Biology, Hamburg
  • 1998: PhD at the faculty of Biology, University of Hamburg
  • 1995-1998: PhD studies at the Max-Planck-Research Group for Structural Molecular Biology, Hamburg
  • 1990-1995: Diploma studies in Biology at the University of Hamburg

Publications

   

2015 (10)

  • Fuertes, E., Standl, M., von Bergen, M., Lehmann, I., Hoffmann, B., Bauer, C.-P., Koletzko, S., Berdel, D., Heinrich, J., (2015):
    Parental allergic disease before and after child birth poses similar risk for childhood allergies
    Allergy
    Volltext (URL)
  • Herberth, G., Offenberg, K., Rolle-Kampczyk, U., Bauer, M., Otto, W., Röder, S., Grützmann, K., Sack, E., Simon, J.-C., Borte, M., von Bergen, M., Lehmann, I., (2015):
    Endogenous metabolites and inflammasome activity in early childhood and links to respiratory diseases
    J. Allergy Clin. Immunol.
    Volltext (URL)
  • Hoeke, H., Roeder, S., Bertsche, T., Lehmann, I., Borte, M., von Bergen, M., Wissenbach, D.K., (2015):
    Monitoring of drug intake during pregnancy by questionnaires and LC-MS/MS drug urine screening: evaluation of both monitoring methods
    Drug Test. Anal.
    Volltext (URL)
  • Hofmann, T., Samsonov, S.A., Pichert, A., Lemmnitzer, K., Schiller, J., Huster, D., Pisabarro, M.T., von Bergen, M., Kalkhof, S., (2015):
    Structural analysis of the interleukin-8/glycosaminoglycan interactions by amide hydrogen/deuterium exchange mass spectrometry
    Methods
    Volltext (URL)
  • Jouy, F., Müller, S.A., Wagner, J., Otto, W., von Bergen, M., Tomm, J.M., (2015):
    Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance
    Proteomics 15 (1), 25 - 33
    Volltext (URL)
  • Kalkhof, S., Dautel, F., Loguercio, S., Baumann, S., Trump, S., Jungnickel, H., Otto, W., Rudzok, S., Potratz, S., Luch, A., Lehmann, I., Beyer, A., von Bergen, M., (2015):
    Pathway and time-resolved benzo[a]pyrene toxicity on Hepa1c1c7 cells at toxic and subtoxic exposure
    J. Proteome Res. 14 (1), 164 - 182
    Volltext (URL)
  • Kostelnik, K.B., Els-Heindl, S., Klöting, N., Baumann, S., von Bergen, M., Beck-Sickinger, A.G., (2015):
    High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry
    Bioorg. Med. Chem.
    Volltext (URL)
  • Pöritz, M., Schiffmann, C.L., Hause, G., Heinemann, U., Seifert, J., Jehmlich, N., von Bergen, M., Nijenhuis, I., Lechner, U., (2015):
    Dehalococcoides mccartyi strain DCMB5 respires a broad spectrum of chlorinated aromatic compounds
    Appl. Environ. Microb. 81 (2), 587 - 596
    Volltext (URL)
  • Sachsenberg, T., Herbst, F.-A., Taubert, M., Kermer, R., Jehmlich, N., von Bergen, M., Seifert, J., Kohlbacher, O., (2015):
    MetaProSIP: Automated inference of stable isotope incorporation rates in proteins for functional metaproteomics
    J. Proteome Res. 14 (2), 619 - 627
    Volltext (URL)
  • Tautenhahn, H.-M., Brückner, S., Baumann, S., Winkler, S., Otto, W., von Bergen, M., Bartels, M., Christ, B., (2015):
    Attenuation of postoperative acute liver failure by mesenchymal stem cell treatment due to metabolic implications
    Ann. Surg.
    Volltext (URL)

2014 (20)

  • Bastida, F., Jehmlich, N., Ondoño, S., von Bergen, M., García, C., Moreno, J.L., (2014):
    Characterization of the microbial community in biological soil crusts dominated by Fulgensia desertorum (Tomin) Poelt and Squamarina cartilaginea (With.) P. James and in the underlying soil
    Soil Biol. Biochem. 76 , 70 - 79
    Volltext (URL)
  • Baumann, S., Rockstroh, M., Bartel, J., Krumsiek, J., Otto, W., Jungnickel, H., Potratz, S., Luch, A., Wilscher, E., Theis, F.J., von Bergen, M., Tomm, J.M., (2014):
    Subtoxic concentrations of benzo[a]pyrene induce metabolic changes and oxidative stress in non-activated and affect the mTOR pathway in activated Jurkat T cells
    Journal of Integrated OMICS 4 (1), 11 - 20
    Volltext (URL)
  • Bozinovski, D., Taubert, M., Kleinsteuber, S., Richnow, H.-H., von Bergen, M., Vogt, C., Seifert, J., (2014):
    Metaproteogenomic analysis of a sulfate-reducing enrichment culture reveals genomic organization of key enzymes in the m-xylene degradation pathway and metabolic activity of proteobacteria
    Syst. Appl. Microbiol. 37 (7), 488 - 501
    Volltext (URL)
  • Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I., (2014):
    Prenatal VOC exposure and redecoration are related to wheezing in early infancy
    Environ. Int. 73 , 393 - 401
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Sack, U., Borte, M., Lehmann, I., (2014):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
    J. Allergy Clin. Immunol. 133 (2), 543 - 550.e4
    Volltext (URL)
  • Imhasly, S., Naegeli, H., Baumann, S., von Bergen, M., Luch, A., Jungnickel, H., Potratz, S., Gerspach, C., (2014):
    Metabolomic biomarkers correlating with hepatic lipidosis in dairy cows
    BMC Vet. Res. 10 , art. 122
    Volltext (URL)
  • Jungandreas, A., Schellenberger Costa, B., Jakob, T., von Bergen, M., Baumann, S., Wilhelm, C., (2014):
    The acclimation of Phaeodactylum tricornutum to blue and red light does not influence the photosynthetic light reaction but strongly disturbs the carbon allocation pattern
    PLOS One 9 (8), e99727
    Volltext (URL)
  • Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I., (2014):
    The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
    Clin. Immunol. 152 (1-2), 68 - 76
    Volltext (URL)
  • Jungnickel, H., Luch, A., Potratz, S., von Bergen, M., Baumann, S., Tarnow, P., (2014):
    Identification of lipidomic biomarkers for coexposure to subtoxic doses of benzo[a]pyrene and cadmium: the toxicological cascade biomarker approach
    Environ. Sci. Technol. 48 (17), 10423 - 10431
    Volltext (URL)
  • Kalkhof, S., Förster, Y., Schmidt, J., Schulz, M.C., Baumann, S., Weißflog, A., Gao, W., Hempel, U., Eckelt, U., Rammelt, S., von Bergen, M., (2014):
    Proteomics and metabolomics for in situ monitoring of wound healing
    Biomed Res. Int. 2014 , art. 934848
    Volltext (URL)
  • Kleindienst, S., Herbst, F.-A., Stagars, M., von Netzer, F., von Bergen, M., Seifert, J., Peplies, J., Amann, R., Musat, F., Lueders, T., Knittel, K., (2014):
    Diverse sulfate-reducing bacteria of the Desulfosarcina/Desulfococcus clade are the key alkane degraders at marine seeps
    ISME J. 8 , 2029 - 2044
    Volltext (URL)
  • Lieder, S., Jahn, M., Seifert, J., von Bergen, M., Müller, S., Takors, R., (2014):
    Subpopulation-proteomics reveal growth rate, but not cell cycling, as a major impact on protein composition in Pseudomonas putida KT2440
    AMB Express 4 , art. 71
    Volltext (URL)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U., (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part I. Batch cultivation with excess of carbon sources
    Syst. Appl. Microbiol. 37 (4), 277 - 286
    Volltext (URL)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U., (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part II. Mimicking environmental conditions during cultivation in retentostats
    Syst. Appl. Microbiol. 37 (4), 287 - 295
    Volltext (URL)
  • Mussotter, F., Haase, A., Tomm, J.M., El Ali, Z., Kerdine-Römer, S., Pallardy, M., von Bergen, M., Luch, A., (2014):
    A proteomics approach to elucidate the role of Nrf2 in primary bone-marrow-derived dendritic cells of mice upon activation by contact allergens
    Toxicol. Lett. 229 (Suppl.), S203
    Volltext (URL)
  • Oberbach, A., Schlichting, N., Neuhaus, J., Kullnick, Y., Lehmann, S., Heinrich, M., Dietrich, A., Mohr, F.W., von Bergen, M., Baumann, S., (2014):
    Establishing a reliable multiple reaction monitoring-based method for the quantification of obesity-associated comorbidities in serum and adipose tissue requires intensive clinical validation
    J. Proteome Res. 13 (12), 5784 - 5800
    Volltext (URL)
  • Rösch, C., Kohajda, T., Röder, S., von Bergen, M., Schlink, U., (2014):
    Relationship between sources and patterns of VOCs in indoor air
    Atmos. Pollut. Res. 5 (1), 129 - 137
    Volltext (URL)
  • Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J., (2014):
    Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
    Anal. Bioanal. Chem. 406 (1), 283 - 291
    Volltext (URL)
  • Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M., (2014):
    Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    J. Proteomics 98 , 59 - 64
    Volltext (URL)
  • Uhlmann, K., Gibb, S., Kalkhof, S., Arroyo-Abad, U., Schulz, C., Hoffmann, B., Stubbins, F., Carpenter, S., Beer, M., von Bergen, M., Feltens, R., (2014):
    Species determination of Culicoides biting midges via peptide profiling using matrix-assisted laser desorption ionization mass spectrometry
    Parasites Vectors 7 , 392
    Volltext (URL)

2013 (30)

  • Baumann, S., Kalkhof, S., Hackermüller, J., Otto, W., Tomm, J.M., Wissenbach, D.K., Rolle-Kampczyk, U., von Bergen, M., (2013):
    Requirements and perspectives for integrating metabolomics with other omics data
    Current Metabolomics 1 (1), 15 - 27
    Volltext (URL)
  • Blumert, C., Kalkhof, S., Brocke-Heidrich, K., Kohajda, T., von Bergen, M., Horn, F., (2013):
    Analysis of the STAT3 interactome using in-situ biotinylation and SILAC
    J. Proteomics 94 , 370 - 386
    Volltext (URL)
  • Bodelier, P.L.E., Meima-Franke, M., Hordijk, C.A., Steenbergh, A.K., Hefting, M.E., Bodrossy, L., von Bergen, M., Seifert, J., (2013):
    Microbial minorities modulate methane consumption through niche partitioning
    ISME J. 7 , 2214 - 2228
    Volltext (URL)
  • Boll, K., Reiche, K., Kasack, K., Mörbt, N., Kretzschmar, A.K., Tomm, J.M., Verhaegh, G., Schalken, J., von Bergen, M., Horn, F., Hackermüller, J., (2013):
    MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma
    Oncogene 32 , 277 - 285
    Volltext (URL)
  • Eberlein, C., Estelmann, S., Seifert, J., von Bergen, M., Müller, M., Meckenstock, R.U., Boll, M., (2013):
    Identification and characterization of 2-naphthoyl-coenzyme A reductase, the prototype of a novel class of dearomatizing reductases
    Mol. Microbiol. 88 (5), 1032 - 1039
    Volltext (URL)
  • Ferrer, M., Ruiz, A., Lanza, F., Haange, S.-B., Oberbach, A., Till, H., Bargiela, R., Campoy, C., Segura, M.T., Richter, M., von Bergen, M., Seifert, J., Suarez, A., (2013):
    Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure
    Environ. Microbiol. 15 (1), 211 - 226
    Volltext (URL)
  • Guazzaroni, M.-E., Herbst, F.-A., Lores, I., Tamames, J., Peláez, A.I., López-Cortés, N., Alcaide, M., del Pozo, M.V., Vieites, J.M., von Bergen, M., Gallego, J.L.R., Bargiela, R., López-López, A., Pieper, D.H., Rosselló-Móra, R., Sánchez, J., Seifert, J., Ferrer, M., (2013):
    Metaproteogenomic insights beyond bacterial response to naphthalene exposure and bio-stimulation
    ISME J. 7 , 122 - 136
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen-Tomm, M., Sack, U., Borte, M., Lehmann, I., (2013):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and with low Treg numbers
    Allergy 68 (Suppl. 97), 628 - 628
    Volltext (URL)
  • Herbst, F.-A., Bahr, A., Duarte, M., Pieper, D.H., Richnow, H.-H., von Bergen, M., Seifert, J., Bombach, P., (2013):
    Elucidation of in situ polycyclic aromatic hydrocarbon degradation by functional metaproteomics (protein-SIP)
    Proteomics 13 (18-19), 2910 - 2920
    Volltext (URL)
  • Herbst, F.-A., Taubert, M., Jehmlich, N., Behr, T., Schmidt, F., von Bergen, M., Seifert, J., (2013):
    Sulfur-34S stable isotope labeling of amino acids for quantification (SULAQ34) of proteomic changes in Pseudomonas fluorescens during naphthalene degradation
    Mol. Cell. Proteomics 12 (8), 2060 - 2069
    Volltext (URL)
  • Jahn, M., Seifert, J., Hübschmann, T., von Bergen, M., Harms, H., Müller, S., (2013):
    Comparison of preservation methods for bacterial cells in cytomics and proteomics
    Journal of Integrated OMICS 3 (1), 25 - 33
    Volltext (URL)
  • Jahn, M., Seifert, J., von Bergen, M., Schmid, A., Bühler, B., Müller, S., (2013):
    Subpopulation-proteomics in prokaryotic populations
    Curr. Opin. Biotechnol. 24 (1), 79 - 87
    Volltext (URL)
  • Jechalke, S., Franchini, A., Bastida, F., Bombach, P., Rosell, M., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H., (2013):
    Analysis of structure, function, and activity of a benzene-degrading microbial community
    FEMS Microbiol.Ecol. 85 (1), 14 - 26
    Volltext (URL)
  • Kliemt, S., Lange, C., Otto, W., Hintze, V., Möller, S., von Bergen, M., Hempel, U., Kalkhof, S., (2013):
    Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells
    J. Proteome Res. 12 (1), 378 - 389
    Volltext (URL)
  • Kung, J.W., Seifert, J., von Bergen, M., Boll, M., (2013):
    Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus
    J. Bacteriol. 195 (14), 3193 - 3200
    Volltext (URL)
  • Leibeling, S., Maeß, M.B., Centler, F., Kleinsteuber, S., von Bergen, M., Thullner, M., Harms, H., Müller, R.H., (2013):
    Posttranslational oxidative modification of (R)-2-(2,4-dichlorophenoxy)propionate/α-ketoglutarate-dependent dioxygenases (RdpA) leads to improved degradation of 2,4-dichlorophenoxyacetate (2,4-D)
    Eng. Life Sci. 13 (3), 278 - 291
    Volltext (URL)
  • Markle, J.G.M., Frank, D.N., Mortin-Toth, S., Robertson, C.E., Feazel, L.M. , Rolle-Kampczyk, U., von Bergen, M., McCoy, C.D., Macpherson, A.J., Danska, J.S., (2013):
    Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
    Science 339 (6123 ), 1084 - 1088
    Volltext (URL)
  • Müller, S.A., Findeiß, S., Pernitzsch, S.R., Wissenbach, D.K., Stadler, P.F., Hofacker, I.L., von Bergen, M., Kalkhof, S., (2013):
    Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics
    J. Proteomics 86 , 27 - 42
    Volltext (URL)
  • Murugaiyan, J., Rockstroh, M., Wagner, J., Baumann, S., Schorsch, K., Trump, S., Lehmann, I., von Bergen, M., Tomm, J.M., (2013):
    Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism
    Toxicol. Appl. Pharmacol. 269 (3), 307 - 316
    Volltext (URL)
  • Murugaiyan, J., Weise, C., von Bergen, M., Roesler, U., (2013):
    Two-dimensional proteome reference map of Prototheca zopfii revealed reduced metabolism and enhanced signal transduction as adaptation to an infectious life style
    Proteomics 13 (17), 2664 - 2669
    Volltext (URL)
  • Murugesan, K., Baumann, S., Wissenbach, D.K., Kliemt, S., Kalkhof, S., Otto, W., Mögel, I., Kohajda, T., von Bergen, M., Tomm, J.M., (2013):
    Subtoxic and toxic concentrations of benzene and toluene induce Nrf-2 mediated anti-oxidative stress response and affect the central carbon metabolism in lung epithelial cells A549
    Proteomics 13 (21), 3211 - 3221
    Volltext (URL)
  • Pérez-Cobas, A.E., Gosalbes, M.J., Friedrichs, A., Knecht, H., Artacho, A., Eismann, K., Otto, W., Rojo, D., Bargiela, R., von Bergen, M., Neulinger, S.C., Däumer, C., Heinsen, F.A., Latorre, A., Barbas, C., Seifert, J., Martins dos Santos, V., Ott, S.J., Ferrer, M., Moya, A., (2013):
    Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
    Gut 62 , 1591 - 1601
    Volltext (URL)
  • Seifert, J., Herbst, F.-A., Nielsen, P.H., Planes, F.J., Ferrer, M., von Bergen, M., (2013):
    Bioinformatic progress and applications in metaproteogenomics for bridging the gap between genomic sequences and metabolic functions in microbial communities
    Proteomics 13 (18-19), 2786 - 2804
    Volltext (URL)
  • Siegert, M., Taubert, M., Seifert, J., von Bergen-Tomm, M., Basen, M., Bastida, F., Gehre, M., Richnow, H.-H., Krüger, M., (2013):
    The nitrogen cycle in anaerobic methanotrophic mats of the Black Sea is linked to sulfate reduction and biomass decomposition
    FEMS Microbiol.Ecol. 86 (2), 231 - 245
    Volltext (URL)
  • Taubert, M., von Bergen-Tomm, M., Seifert, J., (2013):
    Limitations in detection of 15N incorporation by mass spectrometry in protein-based stable isotope probing (protein-SIP)
    Anal. Bioanal. Chem. 405 (12), 3989 - 3996
    Volltext (URL)
  • Tomm, J.M., Krause, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M., (2013):
    Pyruvate kinase and phosphopyruvate hydratase as novel IgE reactive proteins in prawn
    J. Invest. Allergol. Clin. Immunol. 23 (6), 443 - 445
  • Tomm, J.M., Otto, W., Servos, U., Bertram, B., von Bergen, M., Baumann, S., (2013):
    Starvation of Jurkat T cells causes metabolic switch from glycolysis to lipolysis as revealed by comprehensive GC-qMS
    Journal of Integrated OMICS 3 (1), 70 - 74
    Volltext (URL)
  • Tomm, J.M., van Do, T., Jende, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M., (2013):
    Identification of new potential allergens from Nile perch (Lates niloticus) and Cod (Gadus morhua)
    J. Invest. Allergol. Clin. Immunol. 23 (3), 159 - 167
  • von Bergen, M., Jehmlich, N., Taubert, M., Vogt, C., Bastida, F., Herbst, F.-A., Schmidt, F., Richnow, H.-H., Seifert, J., (2013):
    Insights from quantitative metaproteomics and protein-stable isotope probing into microbial ecology
    ISME J. 7 (10), 1877 - 1885
    Volltext (URL)
  • Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I., (2013):
    Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
    Allergy 68 (2), 220 - 228
    Volltext (URL)

2012 (25)

  • Baumgarten, T., Sperling, S., Seifert, J., von Bergen, M., Steiniger, F., Wick, L.Y., Heipieper, H.J., (2012):
    Membrane vesicle formation as a multiple-stress response mechanism enhances Pseudomonas putida DOT-T1E cell surface hydrophobicity and biofilm formation
    Appl. Environ. Microb. 78 (17), 6217 - 6224
    Volltext (URL)
  • Bönisch, U., Böhme, A., Kohajda, T., Mögel, I., Schütze, N., von Bergen, M., Simon, J.C., Lehmann, I., Polte, T., (2012):
    Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model
    PLoS One 7 (7), e39817
    Volltext (URL)
  • Bozinovski, D., Herrmann, S., Richnow, H.-H., von Bergen, M., Seifert, J., Vogt, C., (2012):
    Functional analysis of an anaerobic m-xylene-degrading enrichment culture using protein-based stable isotope probing
    FEMS Microbiol.Ecol. 81 (1), 134 - 144
    Volltext (URL)
  • Goettsch, C., Kliemt, S., Sinningen, K., von Bergen, M., Hofbauer, L.C., Kalkhof, S., (2012):
    Quantitative proteomics reveals novel functions of osteoclast-associated receptor in STAT signaling and cell adhesion in human endothelial cells
    J. Mol. Cell. Cardiol. 53 (6), 829 - 837
    Volltext (URL)
  • Gündel, U., Kalkhof, S., Zitzkat, D.P., von Bergen, M., Altenburger, R., Küster, E., (2012):
    Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome
    Ecotox. Environ. Safe. 76 (1), 11 - 22
    Volltext (URL)
  • Haange, S.-B., Oberbach, A., Schlichting, N., Hugenholtz, F., Smidt, H., von Bergen, M., Till, H., Seifert, J., (2012):
    Metaproteome analysis and molecular genetics of rat intestinal microbiota reveals section and localisation resolved species distribution and enzymatic functionalities
    J. Proteome Res. 11 (11), 5406 - 5417
    Volltext (URL)
  • Haas, S., Jahnke, H.-G., Moerbt, N., von Bergen, M., Aharinejad, S., Andrukhova, O., Robitzki, A.A., (2012):
    DIGE proteome analysis reveals suitability of ischemic cardiac in vitro model for studying cellular response to acute ischemia and regeneration
    PLoS One 7 (2), e31669
    Volltext (URL)
  • Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I., (2012):
    Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
    Allergy 67 (Suppl. 96), 574 - 574
    Volltext (URL)
  • Jehmlich, N., Kopinke, F.-D., Lenhard, S., Vogt, C., Herbst, F.-A., Seifert, J., Lissner, U., Völker, U., Schmidt, F., von Bergen, M., (2012):
    Sulfur-36S stable isotope labeling of amino acids for quantification (SULAQ)
    Proteomics 12 (1), 37 - 42
    Volltext (URL)
  • Kespohl, S., Kotschy-Lang, N., Tomm, J.M., von Bergen, M., Maryska, S., Brüning, T., Raulf-Heimsoth, M., (2012):
    Occupational IgE-mediated softwood allergy: characterization of the causative allergen
    Int. Arch. Allergy Immunol. 157 (2), 202 - 208
    Volltext (URL)
  • Marco-Urrea, E., Seifert, J., von Bergen, M., Adrian, L., (2012):
    Stable isotope peptide mass spectrometry to decipher amino acid metabolism in Dehalococcoides strain CBDB1
    J. Bacteriol. 194 (16), 4169 - 4177
    Volltext (URL)
  • Morris, B.E.L., Herbst, F.-A., Bastida, F., Seifert, J., von Bergen, M., Richnow, H.-H., Suflita, J.M., (2012):
    Microbial interactions during residual oil and n-fatty acid metabolism by a methanogenic consortium
    Environ. Microbiol. Rep. 4 (3), 297 - 306
    Volltext (URL)
  • Müller, S.A., van der Smissen, A., von Feilitzsch, M., Anderegg, U., Kalkhof, S., von Bergen, M., (2012):
    Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix
    J. Mater. Sci.-Mater. Med. 23 (12), 3053 - 3065
    Volltext (URL)
  • Oberbach, A., von Bergen, M., Blueher, S., Lehmann, S., Till, H., (2012):
    Combined serum proteomic and metabonomic profiling after laparoscopic sleeve gastrectomy in children and adolescents
    J. Laparoendosc. Adv. Surg. Tech. 22 (2), 184 - 188
    Volltext (URL)
  • Oberender, J., Kung, J.W., Seifert, J., von Bergen, M., Boll, M., (2012):
    Identification and characterization of a succinyl-coenzyme A (CoA):benzoate CoA transferase in Geobacter metallireducens
    J. Bacteriol. 194 (10), 2501 - 2508
    Volltext (URL)
  • Pohler, P., Lehmann, J., Veneruso, V., Tomm, J., von Bergen, M., Lambrecht, B., Kohn, B., Weingart, C., Müller, T.H., Seltsam, A., (2012):
    Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model
    Transfusion 52 (11), 2414 - 2426
    Volltext (URL)
  • Reinhold, A., Westermann, M., Seifert, J., von Bergen, M., Schubert, T., Diekert, G., (2012):
    Impact of vitamin B12 on the formation of the tetrachloroethene reductive dehalogenase in Desulfitobacterium hafniense strain Y51
    Appl. Environ. Microb. 78 (22), 8025 - 8032
    Volltext (URL)
  • Salbach, J., Kliemt, S., Rauner, M., Rachner, T.D., Goettsch, C., Kalkhof, S., von Bergen, M., Möller, S., Schnabelrauch, M., Hintze, V., Scharnweber, D., Hofbauer, L.C., (2012):
    The effect of the degree of sulfation of glycosaminoglycans on osteoclast function and signaling pathways
    Biomaterials 33 (33), 8418 - 8429
    Volltext (URL)
  • Seifert, J., Taubert, M., Jehmlich, N., Schmidt, F., Völker, U., Vogt, C., Richnow, H.H., von Bergen, M., (2012):
    Protein-based stable isotope probing (protein-SIP) in functional metaproteomics
    Mass Spectrom. Rev. 31 (6), 683 - 697
    Volltext (URL)
  • Taubert, M., Vogt, C., Wubet, T., Kleinsteuber, S., Tarkka, M.T., Harms, H., Buscot, F., Richnow, H.-H., von Bergen, M., Seifert, J., (2012):
    Protein-SIP enables time-resolved analysis of the carbon flux in a sulfate-reducing, benzene-degrading microbial consortium
    ISME J. 6 (12), 2291 - 2301
    Volltext (URL)
  • von Bergen, M., Reiche, K., Hösler, N., Rockstroh, M., Horn, F., Hackermüller, J., Tomm, J., (2012):
    A time resolved analysis of nc/mRNA and protein expression throughout Th cell activation
    Immunology 137 (Suppl. S1), 364 - 364
    Volltext (URL)
  • Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J., (2012):
    The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
    Clin. Exp. Allergy 42 (9), 1337 - 1346
    Volltext (URL)
  • Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I., (2012):
    Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
    J. Reprod. Immunol. 94 (1), 53 - 54
    Volltext (URL)
  • Wirth, H., von Bergen, M., Binder, H., (2012):
    Mining SOM expression portraits: feature selection and integrating concepts of molecular function
    BioData Mining 5 (October), art. 18
    Volltext (URL)
  • Wirth, H., von Bergen, M., Murugaiyan, J., Roesler, U., Stokowy, T., Binder, H., (2012):
    MALDI-typing of infectious algae of the genus Prototheca using SOM portraits
    J. Microbiol. Methods 88 (1), 83 - 89
    Volltext (URL)

2011 (21)

  • Bastida, F., Jechalke, S., Bombach, P., Franchini, A.G., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H., (2011):
    Assimilation of benzene carbon through multiple trophic levels traced by different stable isotope probing methodologies
    FEMS Microbiol.Ecol. 77 (2), 357 - 369
    Volltext (URL)
  • Dautel, F., Kalkhof, S., Trump, S., Lehmann, I., Beyer, A., von Bergen, M., (2011):
    Large-scale 2-D DIGE studies - guidelines to overcome pitfalls and challenges along the experimental procedure
    Journal of Integrated OMICS 1 (1), 170 - 179
    Volltext (URL)
  • Dautel, F., Kalkhof, S., Trump, S., Michaelson, J., Beyer, A., Lehmann, I., von Bergen, M., (2011):
    DIGE-based protein expression analysis of B[a]P-exposed hepatoma cells reveals a complex stress response including alterations in oxidative stress, cell cycle control, and cytoskeleton motility at toxic and subacute concentrations
    J. Proteome Res. 10 (2), 379 - 393
    Volltext (URL)
  • Dietrich, A., Blüher, M., Jonas, S., Shang, E., Till, H., von Bergen, M., Oberbach, A., (2011):
    Metabolic effects of sleeve gastrectomy on different serum proteins
    Obes. Surg. 21 (8), 1064 - 1064
    Volltext (URL)
  • Georgieva, D., Seifert, J., Öhler, M., von Bergen, M., Spencer, P., Arni, R.K., Genov, N., Betzel, C., (2011):
    Pseudechis australis venomics: adaptation for a defense against microbial pathogens and recruitment of body transferrin
    J. Proteome Res. 10 (5), 2440 - 2464
    Volltext (URL)
  • Goodman, V., Müller, A., Gröger-Arndt, H., Schlosser, D., Jehmlich, N., Treudler, R., Lehmann, I., Simon, J.-C., von Bergen, M., (2011):
    Identification of spore specific allergen candidates from Penicillium chrysogenum
    Journal of Integrated OMICS 1 (2), 272 - 279
    Volltext (URL)
  • Jehmlich, N., Seifert, J., Taubert, M., Schmidt, F., Vogt, C., Richnow, H.H., von Bergen, M., (2011):
    Protein stable isotope probing
    In: Murrell, J.C., Whiteley, A.S., (eds.)
    Stable isotope probing and related technologies
    ASM Press, Washington, DC, p. 71 - 93
  • Kuntze, K., Kiefer, P., Baumann, S., Seifert, J., von Bergen, M., Vorholt, J.A., Boll, M., (2011):
    Enzymes involved in the anaerobic degradation of meta-substituted halobenzoates
    Mol. Microbiol. 82 (3), 758 - 769
    Volltext (URL)
  • Marco-Urrea, E., Paul, S., Khodaverdi, V., Seifert, J., von Bergen, M., Kretzschmar, U., Adrian, L., (2011):
    Identification and characterization of a Re-Citrate synthase in Dehalococcoides strain CBDB1
    J. Bacteriol. 193 (19), 5171 - 5178
    Volltext (URL)
  • Michaelson, J., Trump, S., Rudzok, S., Gräbsch, C., Madureira, D.J., Dautel, F., Mai, J., Attinger, S., Schirmer, K., von Bergen, M., Lehmann, I., Beyer, A., (2011):
    Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure
    BMC Genomics 12 , art. 502
    Volltext (URL)
  • Mögel, I., Baumann, S., Böhme, A., Kohajda, T., von Bergen, M., Simon, J.-C., Lehmann, I., (2011):
    The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation
    Toxicology 289 (1), 28 - 37
    Volltext (URL)
  • Mörbt, N., Feltens, R., Tomm, J., Kalkhof, S., Mögel, I., Vogt, C., Lehmann, I., von Bergen, M., (2011):
    Chlorinated benzenes cause concomitantly oxidative stress and induction of apoptotic markers in lung epithelial cells (A549) at non-acute toxic concentrations
    J. Proteome Res. 10 (2), 363 - 378
    Volltext (URL)
  • Oberbach, A., Blüher, M., Wirth, H., Till, H., Kovacs, P., Kullnick, Y., Schlichting, N., Tomm, J.M., Rolle-Kampczyk, U., Murugaiyan, J., Binder, H., Dietrich, A., von Bergen, M., (2011):
    Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes
    J. Proteome Res. 10 (10), 4769 - 4788
    Volltext (URL)
  • Oberbach, A., Till, H., Dietrich, A., Shang, E., von Bergen, M., (2011):
    Integrated proteomic and lipidomic analysis of secretory phospholipase A2 and lysophosphatidylcholines metabolism following sleeve gastrectomy
    Obes. Surg. 21 (8), 1064 - 1065
    Volltext (URL)
  • Rockstroh, M., Müller, S.A., Jende, C., Kerzhner, A., von Bergen, M., Tomm, J.M., (2011):
    Cell fractionation - an important tool for compartment proteomics
    Journal of Integrated OMICS 1 (1), 135 - 143
    Volltext (URL)
  • Schmitt, J., Chen, C.M., Apfelbacher, C., Romanos, M., Lehmann, I., Herbarth, O., Schaaf, B., Kraemer, U., von Bergen, M., Wichmann, H.-E., Heinrich, J., (2011):
    Infant eczema, infant sleeping problems, and mental health at 10 years of age: the prospective birth-cohort study LISAplus
    Allergy 66 (3), 404 - 411
    Volltext (URL)
  • Schramedei, K., Mörbt, N., Pfeifer, G., Läuter, J., Rosolowski, M., Tomm, J.M., von Bergen, M., Horn, F., Brocke-Heidrich, K., (2011):
    MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4
    Oncogene 30 (6), 2975 - 2985
    Volltext (URL)
  • Taubert, M., Baumann, S., von Bergen, M., Seifert, J., (2011):
    Exploring the limits of robust detection of incorporation of 13C by mass spectrometry in protein-based stable isotope probing (protein-SIP)
    Anal. Bioanal. Chem. 401 (6), 1975 - 1982
    Volltext (URL)
  • Taubert, M., Jehmlich, N., Vogt, C., Richnow, H.H., Schmidt, F., von Bergen, M., Seifert, J., (2011):
    Time resolved protein-based stable isotope probing (Protein-SIP) analysis allows quantification of induced proteins in substrate shift experiments
    Proteomics 11 (11), 2265 - 2274
    Volltext (URL)
  • Washietl, S., Findeiss, S., Müller, S.A., Kalkhof, S., von Bergen, M., Hofacker, I.L., Stadler, P.F., Goldmann, N., (2011):
    RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data
    RNA-Publ. RNA Soc. 17 (4), 578 - 594
    Volltext (URL)
  • Wirth, H., Löffler, M., von Bergen, M., Binder, H., (2011):
    Expression cartography of human tissues using self organizing maps
    BMC Bioinformatics 12:306
    Volltext (URL)
 

2010

  • Strauber, H., Hubschmann, T., Jehmlich, N., Schmidt, F., von Bergen, M. , Harms, H., and Muller, S. (2010):
    NBDT (3-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-3-toluene)--a novel fluorescent dye for studying mechanisms of toluene uptake into vital bacteria
    Cytometry A 77, 113-120
    http://dx.doi.org/10.1002/cyto.a.20811
  • Selesi, D., Jehmlich, N., von Bergen, M. , Schmidt, F., Rattei, T., Tischler, P., Lueders, T., and Meckenstock, R. U. (2010):
    Combined genomic and proteomic approaches identify gene clusters involved in anaerobic 2-methylnaphthalene degradation in the sulfate-reducing enrichment culture N47
    J Bacteriol 192, 295-306
    http://dx.doi.org/10.1128/JB.00874-09
  • Schirmer, C., Klein, C., von Bergen, M. , Simon, J. C., and Saalbach, A. (2010):
    Human fibroblasts support the expansion of IL-17-producing T cells via up-regulation of IL-23 production by dendritic cells
    Blood116,1715-1725
    http://dx.doi.org/10.1182/blood-2010-01-263509
  • Ohler, M., Georgieva, D., Seifert, J., von Bergen, M. , Arni, R. K., Genov, N., and Betzel, C. (2010):
    The venomics of Bothrops alternatus is a pool of acidic proteins with predominant hemorrhagic and coagulopathic activities
    J Proteome Res 9, 2422-2437
    http://dx.doi.org/10.1021/pr901128x
  • Muller, S. A., Kohajda, T., Findeiss, S., Stadler, P. F., Washietl, S., Kellis, M., von Bergen, M. , and Kalkhof, S. (2010):
    Optimization of parameters for coverage of low molecular weight proteins
    Anal Bioanal Chem
    http://dx.doi.org/10.1007/s00216-010-4093-x
  • Leibeling, S., Schmidt, F., Jehmlich, N., von Bergen, M. , Muller, R. H., and Harms, H. (2010):
    Declining capacity of starving Delftia acidovorans MC1 to degrade phenoxypropionate herbicides correlates with oxidative modification of the initial enzyme
    Environ Sci Technol 44, 3793-3799
    http://dx.doi.org/10.1021/es903619j
  • Kung, J. W., Baumann, S., von Bergen, M. , Muller, M., Hagedoorn, P. L., Hagen, W. R., and Boll, M. (2010):
    Reversible biological Birch reduction at an extremely low redox potential
    J Am Chem Soc 132, 9850-9856
    http://dx.doi.org/10.1021/ja103448u
  • Jehmlich, N., Hubschmann, T., Gesell Salazar, M., Volker, U., Benndorf, D., Muller, S., von Bergen, M. , and Schmidt, F. (2010):
    Advanced tool for characterization of microbial cultures by combining cytomics and proteomics
    Appl Microbiol Biotechnol 88, 575-584
    http://dx.doi.org/10.1007/s00253-010-2753-6
  • Jehmlich, N., Fetzer, I., Seifert, J., Mattow, J., Vogt, C., Harms, H., Thiede, B., Richnow, H. H., von Bergen, M. , and Schmidt, F. (2010):
    Decimal place slope, a fast and precise method for quantifying 13C incorporation levels for detecting the metabolic activity of microbial species
    Mol Cell Proteomics 9, 1221-1227
    http://dx.doi.org/10.1074/mcp.M900407-MCP200
  • Georgieva, D., Redecke, L., von Bergen, M. , Genov, N., and Betzel, C. (2010):
    Interactions of ginkgolides A and B with a recombinant human prion protein
    Protein Pept Lett 17, 399-404
    http://www.benthamdirect.org/pages/b_viewarticle.php?3157685
  • Georgieva, D., Ohler, M., Seifert, J., von Bergen, M. , Arni, R. K., Genov, N., and Betzel, C. (2010):
    Snake venomic of Crotalus durissus terrificus--correlation with pharmacological activities
    J Proteome Res 9, 2302-2316
    http://dx.doi.org/10.1021/pr901042p
  • Fetzer, I., Jehmlich, N., Vogt, C., Richnow, H. H., Seifert, J., Harms, H., von Bergen, M. , and Schmidt, F. (2010):
    Calculation of partial isotope incorporation into peptides measured by mass spectrometry
    BMC Res Notes 3, 178
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913921/?tool=pubmed
  • Feltens, R., Gorner, R., Kalkhof, S., Groger-Arndt, H., and von Bergen, M. (2010):
    Discrimination of different species from the genus Drosophila by intact protein profiling using matrix-assisted laser desorption ionization mass spectrometry
    BMC Evol Biol 10, 95
    http://dx.doi.org/10.1186/1471-2148-10-95
  • Bastida, F., Rosell, M., Franchini, A. G., Seifert, J., Finsterbusch, S., Jehmlich, N., Jechalke, S., von Bergen, M. , and Richnow, H. H. (2010):
    Elucidating MTBE degradation in a mixed consortium using a multidisciplinary approach
    FEMS Microbiol Ecol 73, 370-384
    http://dx.DOI.org/10.1111/j.1574-6941.2010.00889.x
  • 2009

  • Wischgoll, S., Taubert, M., Peters, F., Jehmlich, N., von Bergen, M. , and Boll, M. (2009):
    Decarboxylating and nondecarboxylating glutaryl-coenzyme A dehydrogenases in the aromatic metabolism of obligately anaerobic bacteria
    J Bacteriol 191, 4401-4409
    http://dx.doi.org/10.1128/JB.00205-09
  • Schleinitz, K. M., Schmeling, S., Jehmlich, N., von Bergen, M. , Harms, H., Kleinsteuber, S., Vogt, C., and Fuchs, G. (2009):
    Phenol degradation in the strictly anaerobic iron-reducing bacterium Geobacter metallireducens GS-15
    Appl Environ Microbiol 75, 3912-3919
    http://dx.doi.org/10.1128/AEM.01525-08
  • Risch, M., Georgieva, D., von Bergen, M. , Jehmlich, N., Genov, N., Arni, R. K., and Betzel, C. (2009):
    Snake venomics of the Siamese Russell's viper (Daboia russelli siamensis) -- relation to pharmacological activities
    J Proteomics 72, 256-269
    http://dx.doi.org/10.1016/j.jprot.2009.01.006
  • Rehders, D., Claasen, B., Redecke, L., Buschke, A., Reibe, C., Jehmlich, N., von Bergen, M. , Betzel, C., and Meyer, B. (2009):
    Peptide NMHRYPNQ of the cellular prion protein (PrP(C)) inhibits aggregation and is a potential key for understanding prion-prion interactions
    J Mol Biol 392, 198-207
    http://dx.doi.org/ 10.1016/j.jmb.2009.07.014
  • Morbt, N., Mogel, I., Kalkhof, S., Feltens, R., Roder-Stolinski, C., Zheng, J., Vogt, C., Lehmann, I., and von Bergen, M. (2009):
    Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism
    Proteomics 9, 4920-4933
    http://dx.doi.org/10.1002/pmic.200800836
  • Junghanns, C., Pecyna, M. J., Bohm, D., Jehmlich, N., Martin, C., von Bergen, M. , Schauer, F., Hofrichter, M., and Schlosser, D. (2009):
    Biochemical and molecular genetic characterisation of a novel laccase produced by the aquatic ascomycete Phoma sp. UHH 5-1-03
    Appl Microbiol Biotechnol 84, 1095-1105
    http://dx.doi.org/10.1007/s00253-009-2028-2
  • Jehmlich, N., Schmidt, F., Taubert, M., Seifert, J., von Bergen, M. , Richnow, H. H., and Vogt, C. (2009):
    Comparison of methods for simultaneous identification of bacterial species and determination of metabolic activity by protein-based stable isotope probing (Protein-SIP) experiments
    Rapid Commun Mass Spectrom 23, 1871-1878
    http://dx.doi.org/10.1002/rcm.4084
  • Heine, F., Stahl, F., Strauber, H., Wiacek, C., Benndorf, D., Repenning, C., Schmidt, F., Scheper, T., von Bergen, M. , Harms, H., and Muller, S. (2009):
    Prediction of flocculation ability of brewing yeast inoculates by flow cytometry, proteome analysis, and mRNA profiling
    Cytometry A 75, 140-147
    http://dx.doi.org/10.1002/cyto.a.20661
  • Benndorf, D., Vogt, C., Jehmlich, N., Schmidt, Y., Thomas, H., Woffendin, G., Shevchenko, A., Richnow, H. H., and von Bergen, M. (2009):
    Improving protein extraction and separation methods for investigating the metaproteome of anaerobic benzene communities within sediments
    Biodegradation 20, 737-750
    http://dx.doi.org/10.1007/s10532-009-9261-3
  • 2008

  • Thiele, B., Rieder, O., Jehmlich, N., von Bergen, M. , Muller, M., and Boll, M. (2008):
    Aromatizing cyclohexa-1,5-diene-1-carbonyl-coenzyme A oxidase. Characterization and its role in anaerobic aromatic metabolism
    J Biol Chem 283, 20713-20721
    http://dx.doi.org/10.1074/jbc.M802841200
  • Roder-Stolinski, C., Fischader, G., Oostingh, G. J., Feltens, R., Kohse, F., von Bergen, M. , Morbt, N., Eder, K., Duschl, A., and Lehmann, I. (2008):
    Styrene induces an inflammatory response in human lung epithelial cells via oxidative stress and NF-kappaB activation
    Toxicol Appl Pharmacol 231, 241-247
    http://dx.doi.org/10.1016/j.taap.2008.04.010
  • Johannes, J., Bluschke, A., Jehmlich, N., von Bergen, M. , and Boll, M. (2008):
    Purification and characterization of active-site components of the putative p-cresol methylhydroxylase membrane complex from Geobacter metallireducens
    J Bacteriol 190, 6493-6500
    http://dx.doi.org/10.1128/JB.00790-08
  • Jehmlich, N., Schmidt, F., von Bergen, M. , Richnow, H. H., and Vogt, C. (2008):
    Protein-based stable isotope probing (Protein-SIP) reveals active species within anoxic mixed cultures
    ISME J 2, 1122-1133
    http://dx.doi.org/10.1038/ismej.2008.64
  • Jehmlich, N., Schmidt, F., Hartwich, M., von Bergen, M. , Richnow, H. H., and Vogt, C. (2008):
    Incorporation of carbon and nitrogen atoms into proteins measured by protein-based stable isotope probing (Protein-SIP)
    Rapid Commun Mass Spectrom 22, 2889-2897
    http://dx.doi.org/10.1002/rcm.3684
  • Jeganathan, S., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2008):
    The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments
    Biochemistry 47, 10526-10539
    http://dx.doi.org/10.1021/bi800783d
  • Hehemann, J. H., Redecke, L., Murugaiyan, J., von Bergen, M. , Betzel, C., and Saborowski, R. (2008):
    Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus
    Biochem Biophys Res Commun 370, 566-571
    http://dx.doi.org/10.1016/j.bbrc.2008.03.128
  • Georgieva, D., Risch, M., Kardas, A., Buck, F., von Bergen, M. , and Betzel, C. (2008):
    Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis
    J Proteome Res 7, 866-886
    http://dx.doi.org/10.1021/pr070376c
  • Benndorf, D., Muller, A., Bock, K., Manuwald, O., Herbarth, O., and von Bergen, M. (2008):
    Identification of spore allergens from the indoor mould Aspergillus versicolor
    Allergy 63, 454-460
    http://dx.doi.org/10.1111/j.1398-9995.2007.01603.x
  • Andronesi, O. C., von Bergen, M. , Biernat, J., Seidel, K., Griesinger, C., Mandelkow, E., and Baldus, M. (2008):
    Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy
    J Am Chem Soc 130, 5922-5928
    http://dx.doi.org/10.1021/ja7100517
  • 2007

  • Santos, P. M., Roma, V., Benndorf, D., von Bergen, M. , Harms, H., and Sa-Correia, I. (2007):
    Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 revealed by quantitative proteomics
    OMICS 11, 233-251
    http://dx.doi.org/10.1089/omi.2007.0009
  • Redecke, L., von Bergen, M. , Clos, J., Konarev, P. V., Svergun, D. I., Fittschen, U. E., Broekaert, J. A., Bruns, O., Georgieva, D., Mandelkow, E., Genov, N., and Betzel, C. (2007):
    Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro
    J Struct Biol 157, 308-320
    http://dx.doi.org/10.1016/j.jsb.2006.06.013
  • Mukrasch, M. D., von Bergen, M. , Biernat, J., Fischer, D., Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2007):
    The "jaws" of the tau-microtubule interaction
    J Biol Chem 282, 12230-12239
    http://dx.doi.org/10.1074/jbc.M607159200
  • Martin, C., Pecyna, M., Kellner, H., Jehmlich, N., Junghanns, C., Benndorf, D., von Bergen, M. , and Schlosser, D. (2007):
    Purification and biochemical characterization of a laccase from the aquatic fungus Myrioconium sp. UHH 1-13-18-4 and molecular analysis of the laccase-encoding gene
    Appl Microbiol Biotechnol 77, 613-624
    http://dx.doi.org/10.1007/s00253-007-1207-2
  • Mandelkow, E., von Bergen, M. , Biernat, J., and Mandelkow, E. M. (2007):
    Structural principles of tau and the paired helical filaments of Alzheimer's disease
    Brain Pathol 17, 83-90
    http://dx.doi.org/10.1111/j.1750-3639.2007.00053.x
  • Gundel, U., Benndorf, D., von Bergen, M. , Altenburger, R., and Kuster, E. (2007):
    Vitellogenin cleavage products as indicators for toxic stress in zebra fish embryos: a proteomic approach
    Proteomics 7, 4541-4554
    http://dx.doi.org/10.1002/pmic.200700381
  • Fischer, D., Mukrasch, M. D., von Bergen, M. , Klos-Witkowska, A., Biernat, J., Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2007):
    Structural and microtubule binding properties of tau mutants of frontotemporal dementias
    Biochemistry 46, 2574-2582
    http://dx.doi.org/10.1021/bi061318s
  • Benndorf, D., Balcke, G. U., Harms, H., and von Bergen, M. (2007):
    Functional metaproteome analysis of protein extracts from contaminated soil and groundwater
    ISME J 1, 224-234
    http://dx.doi.org/10.1038/ismej.2007.39
  • 2006

  • von Bergen, M. , Barghorn, S., Muller, S. A., Pickhardt, M., Biernat, J., Mandelkow, E. M., Davies, P., Aebi, U., and Mandelkow, E. (2006):
    The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis
    Biochemistry 45, 6446-6457
    http://dx.doi.org/10.1021/bi052530j
  • von Bergen, M. , Barghorn, S., Jeganathan, S., Mandelkow, E. M., and Mandelkow, E. (2006):
    Spectroscopic approaches to the conformation of tau protein in solution and in paired helical filaments
    Neurodegener Dis 3, 197-206
    http://dx.doi.org/10.1159/000095257
  • Khlistunova, I., Biernat, J., Wang, Y., Pickhardt, M., von Bergen, M. , Gazova, Z., Mandelkow, E., and Mandelkow, E. M. (2006):
    Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs
    J Biol Chem 281, 1205-1214
    http://dx.doi.org/10.1074/jbc.M507753200
  • Jeganathan, S., von Bergen, M. , Brutlach, H., Steinhoff, H. J., and Mandelkow, E. (2006):
    Global hairpin folding of tau in solution
    Biochemistry 45, 2283-2293
    http://dx.doi.org/10.1021/bi0521543
  • Georgieva, D., Schwark, D., von Bergen, M. , Redecke, L., Genov, N., and Betzel, C. (2006):
    Interactions of recombinant prions with compounds of therapeutical significance
    Biochem Biophys Res Commun 344, 463-470
    http://dx.doi.org/10.1016/j.bbrc.2006.03.135
  • von Bergen, M. , Li, L., and Mandelkow, E. (2005):
    Intrinsic fluorescent detection of tau conformation and aggregation
    Methods Mol Biol 299, 175-184
    http://www.mpasmb-hamburg.mpg.de/mandelkow2/publikationen/index.html
  • 1998-2005

  • von Bergen, M. , Barghorn, S., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2005):
    Tau aggregation is driven by a transition from random coil to beta sheet structure
    Biochim Biophys Acta 1739, 158-166
    http://dx.doi.org/10.1016/j.bbadis.2004.09.010
  • Pickhardt, M., von Bergen, M. , Gazova, Z., Hascher, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2005):
    Screening for inhibitors of tau polymerization
    Curr Alzheimer Res 2, 219-226
    http://dx.DOI.ORG/10.2174/1567205053585891
  • Pickhardt, M., Gazova, Z., von Bergen, M. , Khlistunova, I., Wang, Y., Hascher, A., Mandelkow, E. M., Biernat, J., and Mandelkow, E. (2005):
    Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells
    J Biol Chem 280, 3628-3635
    http://dx.doi.org/10.1074/jbc.M410984200
  • Mukrasch, M. D., Biernat, J., von Bergen, M. , Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2005):
    Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions
    J Biol Chem 280, 24978-24986
    http://dx.doi.org/10.1074/jbc.M501565200
  • Li, L., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2002):
    Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis
    J Biol Chem 277, 41390-41400
    http://dx.doi.org/10.1074/jbc.M206334200
  • von Bergen, M. , Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001):
    Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
    J Biol Chem 276, 48165-48174
    http://dx.doi.org/10.1074/jbc.M105196200
  • von Bergen, M. , Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. (2000):
    Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
    Proc Natl Acad Sci U S A 97, 5129-5134
    http://www.pnas.org/content/97/10/5129.abstract
  • Friedhoff, P., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2000):
    Structure of tau protein and assembly into paired helical filaments
    Biochim Biophys Acta 1502, 122-132
    http://dx.doi.org/10.1016/S0925-4439(00)00038-7
  • Barghorn, S., Zheng-Fischhofer, Q., Ackmann, M., Biernat, J., von Bergen, M. , Mandelkow, E. M., and Mandelkow, E. (2000):
    Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
    Biochemistry 39, 11714-11721
    http://dx.doi.org/bi000850r
  • Schneider, A., Biernat, J., von Bergen, M. , Mandelkow, E., and Mandelkow, E. M. (1999):
    Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
    Biochemistry 38, 3549-3558
    http://www.ncbi.nlm.nih.gov/pubmed/10995239
  • Friedhoff, P., von Bergen, M. , Mandelkow, E. M., Davies, P., and Mandelkow, E. (1998):
    A nucleated assembly mechanism of Alzheimer paired helical filaments
    Proc Natl Acad Sci U S A 95, 15712-15717
    http://dx.doi.org/10.1016/S0925-4439(00)00038-7

Latest News

Preis für Massenspektrometrie in den Biowissenschaften

Gemeinsam wurden Martin von Bergen und Jana Seifert mit dem „Preis für Massenspektrometrie in den Biowissenschaften“ ausgezeichnet. Der von Waters mit 5000 Euro dotierte Preis wurde ihnen für Ihre Arbeiten über "Stable isotope labelling and mass spectrometric analysis of peptides allows tracking of isotopic flux in microbial communities" von der Jury verliehen.

                                          

aktuelle Publikationen

2015 (4)

  • Jouy, F., Müller, S.A., Wagner, J., Otto, W., von Bergen, M., Tomm, J.M. (2015):
    Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance
    Proteomics 15 (1), 25 - 33
    Volltext (URL)
  • Kalkhof, S., Dautel, F., Loguercio, S., Baumann, S., Trump, S., Jungnickel, H., Otto, W., Rudzok, S., Potratz, S., Luch, A., Lehmann, I., Beyer, A., von Bergen, M. (2015):
    Pathway and time-resolved benzo[a]pyrene toxicity on Hepa1c1c7 cells at toxic and subtoxic exposure
    J. Proteome Res. 14 (1), 164 - 182
    Volltext (URL)
  • Pöritz, M., Schiffmann, C.L., Hause, G., Heinemann, U., Seifert, J., Jehmlich, N., von Bergen, M., Nijenhuis, I., Lechner, U. (2015):
    Dehalococcoides mccartyi strain DCMB5 respires a broad spectrum of chlorinated aromatic compounds
    Appl. Environ. Microb. 81 (2), 587 - 596
    Volltext (URL)
  • Sachsenberg, T., Herbst, F.-A., Taubert, M., Kermer, R., Jehmlich, N., von Bergen, M., Seifert, J., Kohlbacher, O. (2015):
    MetaProSIP: Automated inference of stable isotope incorporation rates in proteins for functional metaproteomics
    J. Proteome Res. 14 (2), 619 - 627
    Volltext (URL)

2014 (18)

  • Bastida, F., Jehmlich, N., Ondoño, S., von Bergen, M., García, C., Moreno, J.L. (2014):
    Characterization of the microbial community in biological soil crusts dominated by Fulgensia desertorum (Tomin) Poelt and Squamarina cartilaginea (With.) P. James and in the underlying soil
    Soil Biol. Biochem. 76 , 70 - 79
    Volltext (URL)
  • Bozinovski, D., Taubert, M., Kleinsteuber, S., Richnow, H.-H., von Bergen, M., Vogt, C., Seifert, J. (2014):
    Metaproteogenomic analysis of a sulfate-reducing enrichment culture reveals genomic organization of key enzymes in the m-xylene degradation pathway and metabolic activity of proteobacteria
    Syst. Appl. Microbiol. 37 (7), 488 - 501
    Volltext (URL)
  • Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I. (2014):
    Prenatal VOC exposure and redecoration are related to wheezing in early infancy
    Environ. Int. 73 , 393 - 401
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Sack, U., Borte, M., Lehmann, I. (2014):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
    J. Allergy Clin. Immunol. 133 (2), 543 - 550.e4
    Volltext (URL)
  • Imhasly, S., Naegeli, H., Baumann, S., von Bergen, M., Luch, A., Jungnickel, H., Potratz, S., Gerspach, C. (2014):
    Metabolomic biomarkers correlating with hepatic lipidosis in dairy cows
    BMC Vet. Res. 10 , art. 122
    Volltext (URL)
  • Jungandreas, A., Schellenberger Costa, B., Jakob, T., von Bergen, M., Baumann, S., Wilhelm, C. (2014):
    The acclimation of Phaeodactylum tricornutum to blue and red light does not influence the photosynthetic light reaction but strongly disturbs the carbon allocation pattern
    PLOS One 9 (8), e99727
    Volltext (URL)
  • Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I. (2014):
    The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
    Clin. Immunol. 152 (1-2), 68 - 76
    Volltext (URL)
  • Jungnickel, H., Luch, A., Potratz, S., von Bergen, M., Baumann, S., Tarnow, P. (2014):
    Identification of lipidomic biomarkers for coexposure to subtoxic doses of benzo[a]pyrene and cadmium: the toxicological cascade biomarker approach
    Environ. Sci. Technol. 48 (17), 10423 - 10431
    Volltext (URL)
  • Kalkhof, S., Förster, Y., Schmidt, J., Schulz, M.C., Baumann, S., Weißflog, A., Gao, W., Hempel, U., Eckelt, U., Rammelt, S., von Bergen, M. (2014):
    Proteomics and metabolomics for in situ monitoring of wound healing
    Biomed Res. Int. 2014 , art. 934848
    Volltext (URL)
  • Kleindienst, S., Herbst, F.-A., Stagars, M., von Netzer, F., von Bergen, M., Seifert, J., Peplies, J., Amann, R., Musat, F., Lueders, T., Knittel, K. (2014):
    Diverse sulfate-reducing bacteria of the Desulfosarcina/Desulfococcus clade are the key alkane degraders at marine seeps
    ISME J. 8 , 2029 - 2044
    Volltext (URL)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U. (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part II. Mimicking environmental conditions during cultivation in retentostats
    Syst. Appl. Microbiol. 37 (4), 287 - 295
    Volltext (URL)
  • Marozava, S., Röling, W.F.M., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U. (2014):
    Physiology of Geobacter metallireducens under excess and limitation of electron donors. Part I. Batch cultivation with excess of carbon sources
    Syst. Appl. Microbiol. 37 (4), 277 - 286
    Volltext (URL)
  • Mussotter, F., Haase, A., Tomm, J.M., El Ali, Z., Kerdine-Römer, S., Pallardy, M., von Bergen, M., Luch, A. (2014):
    A proteomics approach to elucidate the role of Nrf2 in primary bone-marrow-derived dendritic cells of mice upon activation by contact allergens
    Toxicol. Lett. 229 (Suppl.), S203
    Volltext (URL)
  • Oberbach, A., Schlichting, N., Neuhaus, J., Kullnick, Y., Lehmann, S., Heinrich, M., Dietrich, A., Mohr, F.W., von Bergen, M., Baumann, S. (2014):
    Establishing a reliable multiple reaction monitoring-based method for the quantification of obesity-associated comorbidities in serum and adipose tissue requires intensive clinical validation
    J. Proteome Res. 13 (12), 5784 - 5800
    Volltext (URL)
  • Rösch, C., Kohajda, T., Röder, S., von Bergen, M., Schlink, U. (2014):
    Relationship between sources and patterns of VOCs in indoor air
    Atmos. Pollut. Res. 5 (1), 129 - 137
    Volltext (URL)
  • Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J. (2014):
    Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
    Anal. Bioanal. Chem. 406 (1), 283 - 291
    Volltext (URL)
  • Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M. (2014):
    Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    J. Proteomics 98 , 59 - 64
    Volltext (URL)
  • Uhlmann, K., Gibb, S., Kalkhof, S., Arroyo-Abad, U., Schulz, C., Hoffmann, B., Stubbins, F., Carpenter, S., Beer, M., von Bergen, M., Feltens, R. (2014):
    Species determination of Culicoides biting midges via peptide profiling using matrix-assisted laser desorption ionization mass spectrometry
    Parasites Vectors 7 , 392
    Volltext (URL)

2013 (27)

  • Blumert, C., Kalkhof, S., Brocke-Heidrich, K., Kohajda, T., von Bergen, M., Horn, F. (2013):
    Analysis of the STAT3 interactome using in-situ biotinylation and SILAC
    J. Proteomics 94 , 370 - 386
    Volltext (URL)
  • Bodelier, P.L.E., Meima-Franke, M., Hordijk, C.A., Steenbergh, A.K., Hefting, M.E., Bodrossy, L., von Bergen, M., Seifert, J. (2013):
    Microbial minorities modulate methane consumption through niche partitioning
    ISME J. 7 , 2214 - 2228
    Volltext (URL)
  • Boll, K., Reiche, K., Kasack, K., Mörbt, N., Kretzschmar, A.K., Tomm, J.M., Verhaegh, G., Schalken, J., von Bergen, M., Horn, F., Hackermüller, J. (2013):
    MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma
    Oncogene 32 , 277 - 285
    Volltext (URL)
  • Eberlein, C., Estelmann, S., Seifert, J., von Bergen, M., Müller, M., Meckenstock, R.U., Boll, M. (2013):
    Identification and characterization of 2-naphthoyl-coenzyme A reductase, the prototype of a novel class of dearomatizing reductases
    Mol. Microbiol. 88 (5), 1032 - 1039
    Volltext (URL)
  • Ferrer, M., Ruiz, A., Lanza, F., Haange, S.-B., Oberbach, A., Till, H., Bargiela, R., Campoy, C., Segura, M.T., Richter, M., von Bergen, M., Seifert, J., Suarez, A. (2013):
    Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure
    Environ. Microbiol. 15 (1), 211 - 226
    Volltext (URL)
  • Guazzaroni, M.-E., Herbst, F.-A., Lores, I., Tamames, J., Peláez, A.I., López-Cortés, N., Alcaide, M., del Pozo, M.V., Vieites, J.M., von Bergen, M., Gallego, J.L.R., Bargiela, R., López-López, A., Pieper, D.H., Rosselló-Móra, R., Sánchez, J., Seifert, J., Ferrer, M. (2013):
    Metaproteogenomic insights beyond bacterial response to naphthalene exposure and bio-stimulation
    ISME J. 7 , 122 - 136
    Volltext (URL)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen-Tomm, M., Sack, U., Borte, M., Lehmann, I. (2013):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and with low Treg numbers
    Allergy 68 (Suppl. 97), 628 - 628
    Volltext (URL)
  • Herbst, F.-A., Bahr, A., Duarte, M., Pieper, D.H., Richnow, H.-H., von Bergen, M., Seifert, J., Bombach, P. (2013):
    Elucidation of in situ polycyclic aromatic hydrocarbon degradation by functional metaproteomics (protein-SIP)
    Proteomics 13 (18-19), 2910 - 2920
    Volltext (URL)
  • Herbst, F.-A., Taubert, M., Jehmlich, N., Behr, T., Schmidt, F., von Bergen, M., Seifert, J. (2013):
    Sulfur-34S stable isotope labeling of amino acids for quantification (SULAQ34) of proteomic changes in Pseudomonas fluorescens during naphthalene degradation
    Mol. Cell. Proteomics 12 (8), 2060 - 2069
    Volltext (URL)
  • Jahn, M., Seifert, J., von Bergen, M., Schmid, A., Bühler, B., Müller, S. (2013):
    Subpopulation-proteomics in prokaryotic populations
    Curr. Opin. Biotechnol. 24 (1), 79 - 87
    Volltext (URL)
  • Jechalke, S., Franchini, A., Bastida, F., Bombach, P., Rosell, M., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H. (2013):
    Analysis of structure, function, and activity of a benzene-degrading microbial community
    FEMS Microbiol.Ecol. 85 (1), 14 - 26
    Volltext (URL)
  • Kliemt, S., Lange, C., Otto, W., Hintze, V., Möller, S., von Bergen, M., Hempel, U., Kalkhof, S. (2013):
    Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells
    J. Proteome Res. 12 (1), 378 - 389
    Volltext (URL)
  • Kung, J.W., Seifert, J., von Bergen, M., Boll, M. (2013):
    Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus
    J. Bacteriol. 195 (14), 3193 - 3200
    Volltext (URL)
  • Leibeling, S., Maeß, M.B., Centler, F., Kleinsteuber, S., von Bergen, M., Thullner, M., Harms, H., Müller, R.H. (2013):
    Posttranslational oxidative modification of (R)-2-(2,4-dichlorophenoxy)propionate/α-ketoglutarate-dependent dioxygenases (RdpA) leads to improved degradation of 2,4-dichlorophenoxyacetate (2,4-D)
    Eng. Life Sci. 13 (3), 278 - 291
    Volltext (URL)
  • Markle, J.G.M., Frank, D.N., Mortin-Toth, S., Robertson, C.E., Feazel, L.M. , Rolle-Kampczyk, U., von Bergen, M., McCoy, C.D., Macpherson, A.J., Danska, J.S. (2013):
    Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
    Science 339 (6123 ), 1084 - 1088
    Volltext (URL)
  • Müller, S.A., Findeiß, S., Pernitzsch, S.R., Wissenbach, D.K., Stadler, P.F., Hofacker, I.L., von Bergen, M., Kalkhof, S. (2013):
    Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics
    J. Proteomics 86 , 27 - 42
    Volltext (URL)
  • Murugaiyan, J., Rockstroh, M., Wagner, J., Baumann, S., Schorsch, K., Trump, S., Lehmann, I., von Bergen, M., Tomm, J.M. (2013):
    Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism
    Toxicol. Appl. Pharmacol. 269 (3), 307 - 316
    Volltext (URL)
  • Murugaiyan, J., Weise, C., von Bergen, M., Roesler, U. (2013):
    Two-dimensional proteome reference map of Prototheca zopfii revealed reduced metabolism and enhanced signal transduction as adaptation to an infectious life style
    Proteomics 13 (17), 2664 - 2669
    Volltext (URL)
  • Murugesan, K., Baumann, S., Wissenbach, D.K., Kliemt, S., Kalkhof, S., Otto, W., Mögel, I., Kohajda, T., von Bergen, M., Tomm, J.M. (2013):
    Subtoxic and toxic concentrations of benzene and toluene induce Nrf-2 mediated anti-oxidative stress response and affect the central carbon metabolism in lung epithelial cells A549
    Proteomics 13 (21), 3211 - 3221
    Volltext (URL)
  • Pérez-Cobas, A.E., Gosalbes, M.J., Friedrichs, A., Knecht, H., Artacho, A., Eismann, K., Otto, W., Rojo, D., Bargiela, R., von Bergen, M., Neulinger, S.C., Däumer, C., Heinsen, F.A., Latorre, A., Barbas, C., Seifert, J., Martins dos Santos, V., Ott, S.J., Ferrer, M., Moya, A. (2013):
    Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
    Gut 62 , 1591 - 1601
    Volltext (URL)
  • Seifert, J., Herbst, F.-A., Nielsen, P.H., Planes, F.J., Ferrer, M., von Bergen, M. (2013):
    Bioinformatic progress and applications in metaproteogenomics for bridging the gap between genomic sequences and metabolic functions in microbial communities
    Proteomics 13 (18-19), 2786 - 2804
    Volltext (URL)
  • Siegert, M., Taubert, M., Seifert, J., von Bergen-Tomm, M., Basen, M., Bastida, F., Gehre, M., Richnow, H.-H., Krüger, M. (2013):
    The nitrogen cycle in anaerobic methanotrophic mats of the Black Sea is linked to sulfate reduction and biomass decomposition
    FEMS Microbiol.Ecol. 86 (2), 231 - 245
    Volltext (URL)
  • Taubert, M., von Bergen-Tomm, M., Seifert, J. (2013):
    Limitations in detection of 15N incorporation by mass spectrometry in protein-based stable isotope probing (protein-SIP)
    Anal. Bioanal. Chem. 405 (12), 3989 - 3996
    Volltext (URL)
  • Tomm, J.M., Krause, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M. (2013):
    Pyruvate kinase and phosphopyruvate hydratase as novel IgE reactive proteins in prawn
    J. Invest. Allergol. Clin. Immunol. 23 (6), 443 - 445
  • Tomm, J.M., van Do, T., Jende, C., Simon, J.C., Treudler, R., von Bergen, M., Averbeck, M. (2013):
    Identification of new potential allergens from Nile perch (Lates niloticus) and Cod (Gadus morhua)
    J. Invest. Allergol. Clin. Immunol. 23 (3), 159 - 167
  • von Bergen, M., Jehmlich, N., Taubert, M., Vogt, C., Bastida, F., Herbst, F.-A., Schmidt, F., Richnow, H.-H., Seifert, J. (2013):
    Insights from quantitative metaproteomics and protein-stable isotope probing into microbial ecology
    ISME J. 7 (10), 1877 - 1885
    Volltext (URL)
  • Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I. (2013):
    Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
    Allergy 68 (2), 220 - 228
    Volltext (URL)

2012 (25)

  • Baumgarten, T., Sperling, S., Seifert, J., von Bergen, M., Steiniger, F., Wick, L.Y., Heipieper, H.J. (2012):
    Membrane vesicle formation as a multiple-stress response mechanism enhances Pseudomonas putida DOT-T1E cell surface hydrophobicity and biofilm formation
    Appl. Environ. Microb. 78 (17), 6217 - 6224
    Volltext (URL)
  • Bönisch, U., Böhme, A., Kohajda, T., Mögel, I., Schütze, N., von Bergen, M., Simon, J.C., Lehmann, I., Polte, T. (2012):
    Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model
    PLoS One 7 (7), e39817
    Volltext (URL)
  • Bozinovski, D., Herrmann, S., Richnow, H.-H., von Bergen, M., Seifert, J., Vogt, C. (2012):
    Functional analysis of an anaerobic m-xylene-degrading enrichment culture using protein-based stable isotope probing
    FEMS Microbiol.Ecol. 81 (1), 134 - 144
    Volltext (URL)
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