Dr. Nico Jehmlich

Funktion: Leiter der Mikrobiellen Ökologie Gruppe

Contact



Helmholtz-Zentrum für Umweltforschung - UFZ
Department Molekulare Systembiologie
Permoserstr. 15, 04318 Leipzig
Telefon: +49 341 235 4767
nico.jehmlich@ufz.de
Nico Jehmlich

Social Network



Research Interests


  • Qualitative and quantitative microbial proteomics | metaproteomics
  • Microbial ecology of terrestrial and aquifer communities
  • Identification of microbial key players using protein-stable isotope probing

Education and Background


since 2013 Head of the Microbial Ecology group
Helmholtz-Centre for Environmental Research, Leipzig
2009 - 2013 PostDoc, Functional Genomics
University Medicine Greifswald
2010 - 2011 PostDoc Fellow, Department of Biochemistry
Vanderbilt University, Nashville, USA
2006 - 2009 PhD study, Department of Proteomics
Helmholtz-Centre for Environmental Research, Leipzig
2001 - 2006 Dipl. Biology
University of Leipzig

Publications


2016 (11)

  • Bastida, F., Jehmlich, N., Lima, K., Morris, B.E.L., Richnow, H.H., Hernández, T., von Bergen, M., García, C., (2016):
    The ecological and physiological responses of the microbial community from a semiarid soil to hydrocarbon contamination and its bioremediation using compost amendment
    J. Proteomics 135 , 162 - 169
    Volltext (URL)
  • Haange, S.-B., Jehmlich, N., (2016):
    Proteomic interrogation of the gut microbiota: potential clinical impact
    Expert Rev. Proteomics 13 (6), 535 - 537
    Volltext (URL)
  • Herbst, F.-A., Lünsmann, V., Kjeldal, H., Jehmlich, N., Tholey, A., von Bergen, M., Nielsen, J.L., Hettich, R.L., Seifert, J., Nielsen, P.H., (2016):
    Enhancing metaproteomics—The value of models and defined environmental microbial systems
    Proteomics 16 (5), 783 - 798
    Volltext (URL)
  • Jehmlich, N., Vogt, C., Lünsmann, V., Richnow, H.H., von Bergen, M., (2016):
    Protein-SIP in environmental studies
    Curr. Opin. Biotechnol. 41 , 26 - 33
    Volltext (URL)
  • Lünsmann, V., Kappelmeyer, U., Benndorf, R., Martínez-Lavanchy, P.M., Taubert, A., Adrian, L., Duarte, M., Pieper, D.H., von Bergen, M., Müller, J.A., Heipieper, H.J., Jehmlich, N., (2016):
    In situ protein-SIP highlights Burkholderiaceae as key players degrading toluene by para ring hydroxylation in a constructed wetland model
    Environ. Microbiol. 18 (4), 1176 - 1186
    Volltext (URL)
  • Lünsmann, V., Kappelmeyer, U., Taubert, A., Nijenhuis, I., von Bergen, M., Heipieper, H.J., Müller, J.A., Jehmlich, N., (2016):
    Aerobic toluene degraders in the rhizosphere of a constructed wetland model show diurnal polyhydroxyalkanoate metabolism
    Appl. Environ. Microb. 82 (14), 4126 - 4132
    Volltext (URL)
  • Men, Y., Han, P., Helbling, D.E., Jehmlich, N., Herbold, C., Gulde, R., Onnis-Hayden, A., Gu, A.Z., Johnson, D.R., Wagner, M., Fenner, K., (2016):
    Biotransformation of two pharmaceuticals by the ammonia-oxidizing archaeon Nitrososphaera gargensis
    Environ. Sci. Technol. 50 (9), 4682 - 4692
    Volltext (URL)
  • Oberbach, A., Adams, V., Schlichting, N., Heinrich, M., Kullnick, Y., Lehmann, S., Lehmann, S., Feder, S., Correia, J.C., Mohr, F.-W., Völker, U., Jehmlich, N., (2016):
    Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins
    Clin. Chim. Acta 453 , 114 - 122
    Volltext (URL)
  • Schaubeck, M., Clavel, T., Calasan, J., Lagkouvardos, I., Haange, S.B., Jehmlich, N., Basic, M., Dupont, A., Hornef, M., von Bergen, M., Bleich, A., Haller, D., (2016):
    Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence
    Gut 65 , 225 - 237
    Volltext (URL)
  • Starke, R., Keller, A., Jehmlich, N., Vogt, C., Richnow, H.H., Kleinsteuber, S., von Bergen, M., Seifert, J., (2016):
    Pulsed 13C2-acetate protein-SIP unveils Epsilonproteobacteria as dominant acetate utilizers in a sulfate-reducing microbial community mineralizing benzene
    Microb. Ecol. 71 (4), 901 - 911
    Volltext (URL)
  • Starke, R., Kermer, R., Ullmann-Zeunert, L., Baldwin, I.T., Seifert, J., Bastida, F., von Bergen, M., Jehmlich, N., (2016):
    Bacteria dominate the short-term assimilation of plant-derived N in soil
    Soil Biol. Biochem. 96 , 30 - 38
    Volltext (URL)

2015 (11)

  • Bastida, F., García, C., von Bergen, M., Moreno, J.L., Richnow, H.H., Jehmlich, N., (2015):
    Deforestation fosters bacterial diversity and the cyanobacterial community responsible for carbon fixation processes under semiarid climate: a metaproteomics study
    Appl. Soil Ecol. 93 , 65 - 67
    Volltext (URL)
  • Daims, H., Lebedeva, E.V., Pjevac, P., Han, P., Herbold, C., Albertsen, M., Jehmlich, N., Palatinszky, M., Vierheilig, J., Bulaev, A., Kirkegaard, R.H., von Bergen, M., Rattei, T., Bendinger, B., Nielsen, P.H., Wagner, M., (2015):
    Complete nitrification by Nitrospira bacteria
    Nature 528 (7583), 504 - 509
    Volltext (URL)
  • Goris, T., Schiffmann, C.L., Gadkari, J., Schubert, T., Seifert, J., Jehmlich, N., von Bergen, M., Diekert, G., (2015):
    Proteomics of the organohalide-respiring Epsilonproteobacterium Sulfurospirillum multivorans adapted to tetrachloroethene and other energy substrates
    Sci. Rep. 5 , art. 13794
    Volltext (URL)
  • Grob, C., Taubert, M., Howat, A.M., Burns, O.J., Dixon, J.L., Richnow, H.H., Jehmlich, N., von Bergen, M., Chen, Y., Murrell, J.C., (2015):
    Combining metagenomics with metaproteomics and stable isotope probing reveals metabolic pathways used by a naturally occurring marine methylotroph
    Environ. Microbiol. 17 (10), 4007 - 4018
    Volltext (URL)
  • Hartwig, S., Thomas, C., Krumova, N., Quitzke, V., Türkowsky, D., Jehmlich, N., Adrian, L., Sawers, R.G., (2015):
    Heterologous complementation studies in Escherichia coli with the Hyp accessory protein machinery from Chloroflexi provide insight into [NiFe]-hydrogenase large subunit recognition by the HypC protein family
    Microbiology-(UK) 161 (11), 2204 - 2219
    Volltext (URL)
  • Kümmel, S., Herbst, F.-A., Bahr, A., Duarte, M., Pieper, D.H., Jehmlich, N., Seifert, J., von Bergen, M., Bombach, P., Richnow, H.H., Vogt, C., (2015):
    Anaerobic naphthalene degradation by sulfate-reducing Desulfobacteraceae from various anoxic aquifers
    FEMS Microbiol. Ecol. 91 (3), fiv006
    Volltext (URL)
  • Palatinszky, M., Herbold, C., Jehmlich, N., Pogoda, M., Han, P., von Bergen, M., Lagkouvardos, I., Karst, S.M., Galushko, A., Koch, H., Berry, D., Daims, H., Wagner, M., (2015):
    Cyanate as an energy source for nitrifiers
    Nature 524 , 105 - 108
    Volltext (URL)
  • Pöritz, M., Schiffmann, C.L., Hause, G., Heinemann, U., Seifert, J., Jehmlich, N., von Bergen, M., Nijenhuis, I., Lechner, U., (2015):
    Dehalococcoides mccartyi strain DCMB5 respires a broad spectrum of chlorinated aromatic compounds
    Appl. Environ. Microb. 81 (2), 587 - 596
    Volltext (URL)
  • Sachsenberg, T., Herbst, F.-A., Taubert, M., Kermer, R., Jehmlich, N., von Bergen, M., Seifert, J., Kohlbacher, O., (2015):
    MetaProSIP: Automated inference of stable isotope incorporation rates in proteins for functional metaproteomics
    J. Proteome Res. 14 (2), 619 - 627
    Volltext (URL)
  • Schaubeck, M., Clavel, T., Lagkouvardos, M., Calasan, J., Haange, S.B., Jehmlich, N., von Bergen, M., Basic, M., Bleich, A., Haller, D., (2015):
    Transmissive Crohn's disease-like ileitis is caused by functional dysbiosis in the intestinal microbiota independent of inflammation-driven Paneth cell failure
    J. Crohns Colitis 9 (Suppl. 1), S1 - S1
    Volltext (URL)
  • Seyhan, D., Jehmlich, N., von Bergen, M., Fersch, J., Rother, M., (2015):
    Selenocysteine-independent suppression of UGA codons in the archaeon Methanococcus maripaludis
    Biochim. Biophys. Acta-Gen. Subj. 1850 , 2385 - 2392
    Volltext (URL)

2014 (6)

  • Bastida, F., Jehmlich, N., Ondoño, S., von Bergen, M., García, C., Moreno, J.L., (2014):
    Characterization of the microbial community in biological soil crusts dominated by Fulgensia desertorum (Tomin) Poelt and Squamarina cartilaginea (With.) P. James and in the underlying soil
    Soil Biol. Biochem. 76 , 70 - 79
    Volltext (URL)
  • Oberbach, A., Neuhaus, J., Jehmlich, N., Schlichting, N., Heinrich, M., Kullnick, Y., Mohr, F.-W., Kugler, J., Baumann, S., Völker, U., Adams, V., (2014):
    A global proteome approach in uric acid stimulated human aortic endothelial cells revealed regulation of multiple major cellular pathways
    Int. J. Cardiol. 176 (3), 746 - 752
    Volltext (URL)
  • Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J., (2014):
    Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
    Anal. Bioanal. Chem. 406 (1), 283 - 291
    Volltext (URL)
  • Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M., (2014):
    Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    J. Proteomics 98 , 59 - 64
    Volltext (URL)
  • Stegmaier, P., Jehmlich, N., Golatowski, C., Gesell Salazar, M., Völker, U., Henke, M., (2014):
    Identification of differences in the whole saliva baseline proteome profile that are associated with development of oral mucositis in head and neck cancer patients during treatment with IMRT
    Int. J. Radiat. Oncol. Biol. Phys. 90 (Suppl. 1), S547
    Volltext (URL)
  • Stegmaier, P., Jehmlich, N., Golatowski, C., Gesell Salazar, M., Völker, U., Henke, M., (2014):
    Identification of differences in the whole saliva baseline proteome profile that are associated with development of oral mucositis in head and neck cancer patients during treatment with IMRT
    Strahlenther. Onkol. 190 (Suppl. 1), 142
    Volltext (URL)

2013 (2)

  • Herbst, F.-A., Taubert, M., Jehmlich, N., Behr, T., Schmidt, F., von Bergen, M., Seifert, J., (2013):
    Sulfur-34S stable isotope labeling of amino acids for quantification (SULAQ34) of proteomic changes in Pseudomonas fluorescens during naphthalene degradation
    Mol. Cell. Proteomics 12 (8), 2060 - 2069
    Volltext (URL)
  • von Bergen, M., Jehmlich, N., Taubert, M., Vogt, C., Bastida, F., Herbst, F.-A., Schmidt, F., Richnow, H.-H., Seifert, J., (2013):
    Insights from quantitative metaproteomics and protein-stable isotope probing into microbial ecology
    ISME J. 7 (10), 1877 - 1885
    Volltext (URL)

2012 (2)

  • Jehmlich, N., Kopinke, F.-D., Lenhard, S., Vogt, C., Herbst, F.-A., Seifert, J., Lissner, U., Völker, U., Schmidt, F., von Bergen, M., (2012):
    Sulfur-36S stable isotope labeling of amino acids for quantification (SULAQ)
    Proteomics 12 (1), 37 - 42
    Volltext (URL)
  • Seifert, J., Taubert, M., Jehmlich, N., Schmidt, F., Völker, U., Vogt, C., Richnow, H.H., von Bergen, M., (2012):
    Protein-based stable isotope probing (protein-SIP) in functional metaproteomics
    Mass Spectrom. Rev. 31 (6), 683 - 697
    Volltext (URL)

2011 (3)

  • Goodman, V., Müller, A., Gröger-Arndt, H., Schlosser, D., Jehmlich, N., Treudler, R., Lehmann, I., Simon, J.-C., von Bergen, M., (2011):
    Identification of spore specific allergen candidates from Penicillium chrysogenum
    Journal of Integrated OMICS 1 (2), 272 - 279
    Volltext (URL)
  • Jehmlich, N., Seifert, J., Taubert, M., Schmidt, F., Vogt, C., Richnow, H.H., von Bergen, M., (2011):
    Protein stable isotope probing
    In: Murrell, J.C., Whiteley, A.S., (eds.)
    Stable isotope probing and related technologies
    ASM Press, Washington, DC, p. 71 - 93
  • Taubert, M., Jehmlich, N., Vogt, C., Richnow, H.H., Schmidt, F., von Bergen, M., Seifert, J., (2011):
    Time resolved protein-based stable isotope probing (Protein-SIP) analysis allows quantification of induced proteins in substrate shift experiments
    Proteomics 11 (11), 2265 - 2274
    Volltext (URL)