Dr. Nico Jehmlich

Funktion: Leiter der Mikrobiom Biologie Gruppe


Helmholtz-Zentrum für Umweltforschung - UFZ
Department Molekulare Systembiologie
Permoserstr. 15, 04318 Leipzig
Telefon: +49 341 235 4767
Nico Jehmlich

Social Network

SI Promotion

Research Interests

  • Qualitative and quantitative microbial proteomics | Metaproteomics
  • Microbiome biology of terrestrial and aquifer communities
  • Identification of microbial key players using protein-stable isotope probing
Research Interest

Education and Background

since 2013 Head of the Microbiome Biology group
Helmholtz-Centre for Environmental Research, Leipzig
2009 - 2013 PostDoc, Functional Genomics
University Medicine Greifswald
2010 - 2011 PostDoc Fellow, Department of Biochemistry
Vanderbilt University, Nashville, USA
2006 - 2009 PhD study, Department of Proteomics
Helmholtz-Centre for Environmental Research, Leipzig
2001 - 2006 Dipl. Biology
University of Leipzig


2017 (10)

  • Bastida, F., Torres, I.F., Andrés-Abellán, M., Baldrian, P., López-Mondéjar, R., Větrovský, T., Richnow, H.H., Starke, R., Ondoño, S., García, C., López-Serrano, F., Jehmlich, N., (2017):
    Differential sensitivity of total and active soil microbial communities to drought and forest management
    Glob. Change Biol. 23 (10), 4185 - 4203
    Volltext (URL)
  • Chupani, L., Zusková, É., Niksirat, H., Panáček, A., Lünsmann, V., Haange, S.-B., von Bergen, M., Jehmlich, N., (2017):
    Effects of chronic dietary exposure of zinc oxide nanoparticles on the serum protein profile of juvenile common carp (Cyprinus carpio L.)
    Sci. Total Environ. 579 , 1504 - 1511
    Volltext (URL)
  • Ebenau-Jehle, C., Mergelsberg, M., Fischer, S., Brüls, T., Jehmlich, N., von Bergen, M., Boll, M., (2017):
    An unusual strategy for the anoxic biodegradation of phthalate
    ISME J. 11 (1), 224 - 236
    Volltext (URL)
  • Kadisch, M., Julsing, M.K., Schrewe, M., Jehmlich, N., Scheer, B., von Bergen, M., Schmid, A., Bühler, B., (2017):
    Maximization of cell viability rather than biocatalyst activity improves whole-cell ω-oxyfunctionalization performance
    Biotechnol. Bioeng. 114 (4), 874 - 884
    Volltext (URL)
  • Kiebist, J., Schmidtke, K.-U., Zimmermann, J., Kellner, H., Jehmlich, N., Ullrich, R., Zänder, D., Hofrichter, M., Scheibner, K., (2017):
    A peroxygenase from Chaetomium globosum catalyzes the selective oxygenation of testosterone
    ChemBioChem 18 (6), 563 - 569
    Volltext (URL)
  • Oberbach, A., Haange, S.-B., Schlichting, N., Heinrich, M., Lehmann, S., Till, H., Hugenholtz, F., Kullnick, Y., Smidt, H., Frank, K., Seifert, J., Jehmlich, N., von Bergen, M., (2017):
    Metabolic in vivo labeling highlights differences of metabolically active microbes from the mucosal gastrointestinal microbiome between high-fat and normal chow diet
    J. Proteome Res. 16 (4), 1593 - 1604
    Volltext (URL)
  • Pinaud, L., Ferrari, M.L., Friedman, R., Jehmlich, N., von Bergen, M., Phalipon, A., Sansonetti, P.J., Campbell-Valois, F.-X., (2017):
    Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome
    PLOS One 12 (10), art. e0186920
    Volltext (URL)
  • Starke, R., Bastida, F., Abadía, J., García, C., Nicolás, E., Jehmlich, N., (2017):
    Ecological and functional adaptations to water management in a semiarid agroecosystem: a soil metaproteomics approach
    Sci. Rep. 7 , art. 10221
    Volltext (URL)
  • Starke, R., Müller, M., Gaspar, M., Marz, M., Küsel, K., Totsche, K.U., von Bergen, M., Jehmlich, N., (2017):
    Candidate Brocadiales dominates C, N and S cycling in anoxic groundwater of a pristine limestone-fracture aquifer
    J. Proteomics 152 , 153 - 160
    Volltext (URL)
  • Taubert, M., Grob, C., Howar, A.M., Burns, O.J., Pratscher, J., Jehmlich, N., von Bergen, M., Richnow, H.H., Chen, Y., Murrell, J.C., (2017):
    Methylamine as a nitrogen source for microorganisms from a coastal marine environment
    Environ. Microbiol. 19 (6), 2246 - 2257
    Volltext (URL)

2016 (20)

  • Bastida, F., Jehmlich, N., (2016):
    It's all about functionality: How can metaproteomics help us to discuss the attributes of ecological relevance in soil?
    J. Proteomics 144 , 159 - 161
    Volltext (URL)
  • Bastida, F., Jehmlich, N., Lima, K., Morris, B.E.L., Richnow, H.H., Hernández, T., von Bergen, M., García, C., (2016):
    The ecological and physiological responses of the microbial community from a semiarid soil to hydrocarbon contamination and its bioremediation using compost amendment
    J. Proteomics 135 , 162 - 169
    Volltext (URL)
  • Bastida, F., Torres, I.F., Moreno, J.L., Baldrian, P., Ondoño, S., Ruiz-Navarro, A., Hernández, T., Richnow, H.H., Starke, R., García, C., Jehmlich, N., (2016):
    The active microbial diversity drives ecosystem multifunctionality and is physiologically related to carbon availability in Mediterranean semi-arid soils
    Mol. Ecol. 25 (18), 4660 - 4673
    Volltext (URL)
  • Dey, P., Gola, D., Mishra, A., Malik, A., Kumar, P., Singh, D.K., Patel, N., von Bergen, M., Jehmlich, N., (2016):
    Comparative performance evaluation of multi-metal resistant fungal strains for simultaneous removal of multiple hazardous metals
    J. Hazard. Mater. 318 , 679 - 685
    Volltext (URL)
  • Goris, T., Schiffmann, C.L., Gadkari, J., Adrian, L., von Bergen, M., Diekert, G., Jehmlich, N., (2016):
    Proteomic data set of the organohalide-respiring Epsilonproteobacterium Sulfurospirillum multivorans adapted to tetrachloroethene and other energy substrates
    Data in Brief 8 , 637 - 642
    Volltext (URL)
  • Haange, S.-B., Jehmlich, N., (2016):
    Proteomic interrogation of the gut microbiota: potential clinical impact
    Expert Rev. Proteomics 13 (6), 535 - 537
    Volltext (URL)
  • Herbst, F.-A., Lünsmann, V., Kjeldal, H., Jehmlich, N., Tholey, A., von Bergen, M., Nielsen, J.L., Hettich, R.L., Seifert, J., Nielsen, P.H., (2016):
    Enhancing metaproteomics—The value of models and defined environmental microbial systems
    Proteomics 16 (5), 783 - 798
    Volltext (URL)
  • Jehmlich, N., Vogt, C., Lünsmann, V., Richnow, H.H., von Bergen, M., (2016):
    Protein-SIP in environmental studies
    Curr. Opin. Biotechnol. 41 , 26 - 33
    Volltext (URL)
  • Lünsmann, V., Kappelmeyer, U., Benndorf, R., Martínez-Lavanchy, P.M., Taubert, A., Adrian, L., Duarte, M., Pieper, D.H., von Bergen, M., Müller, J.A., Heipieper, H.J., Jehmlich, N., (2016):
    In situ protein-SIP highlights Burkholderiaceae as key players degrading toluene by para ring hydroxylation in a constructed wetland model
    Environ. Microbiol. 18 (4), 1176 - 1186
    Volltext (URL)
  • Lünsmann, V., Kappelmeyer, U., Taubert, A., Nijenhuis, I., von Bergen, M., Heipieper, H.J., Müller, J.A., Jehmlich, N., (2016):
    Aerobic toluene degraders in the rhizosphere of a constructed wetland model show diurnal polyhydroxyalkanoate metabolism
    Appl. Environ. Microb. 82 (14), 4126 - 4132
    Volltext (URL)
  • Malik, A.A., Chowdhury, S., Schlager, V., Oliver, A., Puissant, J., Vazquez, P.G.M., Jehmlich, N., von Bergen, M., Griffiths, R.I., Gleixner, G., (2016):
    Soil fungal:bacterial ratios are linked to altered carbon cycling
    Front. Microbiol. 7 , art. 1247
    Volltext (URL)
  • Men, Y., Han, P., Helbling, D.E., Jehmlich, N., Herbold, C., Gulde, R., Onnis-Hayden, A., Gu, A.Z., Johnson, D.R., Wagner, M., Fenner, K., (2016):
    Biotransformation of two pharmaceuticals by the ammonia-oxidizing archaeon Nitrososphaera gargensis
    Environ. Sci. Technol. 50 (9), 4682 - 4692
    Volltext (URL)
  • Oberbach, A., Adams, V., Schlichting, N., Heinrich, M., Kullnick, Y., Lehmann, S., Lehmann, S., Feder, S., Correia, J.C., Mohr, F.-W., Völker, U., Jehmlich, N., (2016):
    Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins
    Clin. Chim. Acta 453 , 114 - 122
    Volltext (URL)
  • Schaubeck, M., Clavel, T., Calasan, J., Lagkouvardos, I., Haange, S.B., Jehmlich, N., Basic, M., Dupont, A., Hornef, M., von Bergen, M., Bleich, A., Haller, D., (2016):
    Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence
    Gut 65 , 225 - 237
    Volltext (URL)
  • Schiffmann, C.L., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen, M., Jehmlich, N., (2016):
    Proteomic dataset of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    Data in Brief 7 , 253 - 256
    Volltext (URL)
  • Starke, R., Keller, A., Jehmlich, N., Vogt, C., Richnow, H.H., Kleinsteuber, S., von Bergen, M., Seifert, J., (2016):
    Pulsed 13C2-acetate protein-SIP unveils Epsilonproteobacteria as dominant acetate utilizers in a sulfate-reducing microbial community mineralizing benzene
    Microb. Ecol. 71 (4), 901 - 911
    Volltext (URL)
  • Starke, R., Kermer, R., Ullmann-Zeunert, L., Baldwin, I.T., Seifert, J., Bastida, F., von Bergen, M., Jehmlich, N., (2016):
    Bacteria dominate the short-term assimilation of plant-derived N in soil
    Soil Biol. Biochem. 96 , 30 - 38
    Volltext (URL)
  • Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., Berndt, S.I., Bidlingmaier, M., Broer, L., Cappola, A., Ceda, G.P., Chanock, S., Chen, M.-H., Chen, T.C., Chen, Y.-D.I., Chung, J., Del Greco Miglianico, F., Eriksson, J., Ferrucci, L., Friedrich, N., Gnewuch, C., Goodarzi, M.O., Grarup, N., Guo, T., Hammer, E., Hayes, R.B., Hicks, A.A., Hofman, A., Houwing-Duistermaat, J.J., Hu, F., Hunter, D.J., Husemoen, L.L., Isaacs, A., Jacobs, K.B., Janssen, J.A.M.J.L., Jansson, J.-O., Jehmlich, N., Johnson, S., Juul, A., Karlsson, M., Kilpelainen, T.O., Kovacs, P., Kraft, P., Li, C., Linneberg, A., Liu, Y., Loos, R.J.F., Lorentzon, M., Lu, Y., Maggio, M., Magi, R., Meigs, J., Mellström, D., Nauck, M., Newman, A.B., Pollak, M.N., Pramstaller, P.P., Prokopenko, I., Psaty, B.M., Reincke, M., Rimm, R.B., Rotter, J.I., Saint Pierre, A., Schurmann, C., Seshadri, S., Sjögren, K., Slagboom, P.E., Strickler, H.D., Stumvoll, M., Suh, Y., Sun, Q., Zhang, C., Svensson, J., Tanaka, T., Tare, A., Tönjes, A., Uh, H.-W., van Duijn, C., van Heemst, D., Vandenput, L., Vasan, R.S., Völker, U., Willems, S.M., Ohlsson, C., Wallaschofski, H., Kaplan, R.C., (2016):
    Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
    Aging Cell 15 (5), 811 - 824
    Volltext (URL)
  • Tiedt, O., Mergelsberg, M., Boll, K., Müller, M., Adrian, L., Jehmlich, N., von Bergen, M., Boll, M., (2016):
    ATP-dependent C–F bond cleavage allows the complete degradation of 4-fluoroaromatics without oxygen
    mBio 7 (4), e00990-16
    Volltext (URL)
  • Warnke, M., Jung, T., Dermer, J., Hipp, K., Jehmlich, N., von Bergen, M., Ferlaino, S., Fries, A., Müller, M., Boll, M., (2016):
    25-hydroxyvitamin D3 synthesis by enzymatic steroid side-chain hydroxylation with water
    Angew. Chem.-Int. Edit. 55 (5), 1881 - 1884
    Volltext (URL)

2015 (11)

  • Bastida, F., García, C., von Bergen, M., Moreno, J.L., Richnow, H.H., Jehmlich, N., (2015):
    Deforestation fosters bacterial diversity and the cyanobacterial community responsible for carbon fixation processes under semiarid climate: a metaproteomics study
    Appl. Soil Ecol. 93 , 65 - 67
    Volltext (URL)
  • Daims, H., Lebedeva, E.V., Pjevac, P., Han, P., Herbold, C., Albertsen, M., Jehmlich, N., Palatinszky, M., Vierheilig, J., Bulaev, A., Kirkegaard, R.H., von Bergen, M., Rattei, T., Bendinger, B., Nielsen, P.H., Wagner, M., (2015):
    Complete nitrification by Nitrospira bacteria
    Nature 528 (7583), 504 - 509
    Volltext (URL)
  • Goris, T., Schiffmann, C.L., Gadkari, J., Schubert, T., Seifert, J., Jehmlich, N., von Bergen, M., Diekert, G., (2015):
    Proteomics of the organohalide-respiring Epsilonproteobacterium Sulfurospirillum multivorans adapted to tetrachloroethene and other energy substrates
    Sci. Rep. 5 , art. 13794
    Volltext (URL)
  • Grob, C., Taubert, M., Howat, A.M., Burns, O.J., Dixon, J.L., Richnow, H.H., Jehmlich, N., von Bergen, M., Chen, Y., Murrell, J.C., (2015):
    Combining metagenomics with metaproteomics and stable isotope probing reveals metabolic pathways used by a naturally occurring marine methylotroph
    Environ. Microbiol. 17 (10), 4007 - 4018
    Volltext (URL)
  • Hartwig, S., Thomas, C., Krumova, N., Quitzke, V., Türkowsky, D., Jehmlich, N., Adrian, L., Sawers, R.G., (2015):
    Heterologous complementation studies in Escherichia coli with the Hyp accessory protein machinery from Chloroflexi provide insight into [NiFe]-hydrogenase large subunit recognition by the HypC protein family
    Microbiology-(UK) 161 (11), 2204 - 2219
    Volltext (URL)
  • Kümmel, S., Herbst, F.-A., Bahr, A., Duarte, M., Pieper, D.H., Jehmlich, N., Seifert, J., von Bergen, M., Bombach, P., Richnow, H.H., Vogt, C., (2015):
    Anaerobic naphthalene degradation by sulfate-reducing Desulfobacteraceae from various anoxic aquifers
    FEMS Microbiol. Ecol. 91 (3), fiv006
    Volltext (URL)
  • Palatinszky, M., Herbold, C., Jehmlich, N., Pogoda, M., Han, P., von Bergen, M., Lagkouvardos, I., Karst, S.M., Galushko, A., Koch, H., Berry, D., Daims, H., Wagner, M., (2015):
    Cyanate as an energy source for nitrifiers
    Nature 524 , 105 - 108
    Volltext (URL)
  • Pöritz, M., Schiffmann, C.L., Hause, G., Heinemann, U., Seifert, J., Jehmlich, N., von Bergen, M., Nijenhuis, I., Lechner, U., (2015):
    Dehalococcoides mccartyi strain DCMB5 respires a broad spectrum of chlorinated aromatic compounds
    Appl. Environ. Microb. 81 (2), 587 - 596
    Volltext (URL)
  • Sachsenberg, T., Herbst, F.-A., Taubert, M., Kermer, R., Jehmlich, N., von Bergen, M., Seifert, J., Kohlbacher, O., (2015):
    MetaProSIP: Automated inference of stable isotope incorporation rates in proteins for functional metaproteomics
    J. Proteome Res. 14 (2), 619 - 627
    Volltext (URL)
  • Schaubeck, M., Clavel, T., Lagkouvardos, M., Calasan, J., Haange, S.B., Jehmlich, N., von Bergen, M., Basic, M., Bleich, A., Haller, D., (2015):
    Transmissive Crohn's disease-like ileitis is caused by functional dysbiosis in the intestinal microbiota independent of inflammation-driven Paneth cell failure
    J. Crohns Colitis 9 (Suppl. 1), S1 - S1
    Volltext (URL)
  • Seyhan, D., Jehmlich, N., von Bergen, M., Fersch, J., Rother, M., (2015):
    Selenocysteine-independent suppression of UGA codons in the archaeon Methanococcus maripaludis
    Biochim. Biophys. Acta-Gen. Subj. 1850 , 2385 - 2392
    Volltext (URL)