Dr. Gunda Herberth
Contact
Dr. Gunda Herberth
Scientist, Platform Coordinator of
Cohorts
and Lead (PI) of the LINA study
Helmholtz Centre for
Environmental Research – UFZ
Department of Environmental Immunology
Permoserstr. 15
04318 Leipzig, Germany
Phone: +49 341 6025-1547
Email
Research Interests
• Influence of environmental exposures on the modulation of immune responses and the development of allergic diseases in prospective birth cohort studies
• Regulation of immune cell activity by environmental contaminants with focus on mucosal-associated invariant T cells (MAIT cells)
• Impact of disturbed T cell function (e.g. regulatory T cells, MAIT cells) on the development of health outcomes
Curriculum vitae / Scientific career
2020 - 2023
Deputy Head of the Department of Environmental Immunology at the Helmholtz Centre for Environmental Research - UFZ
2018 - 2020
Acting Head of the Department Environmental Immunology
since 2018
Principle Investigator (PI) of the LINA study (LINA – Impact of prenatal lifestyle factors and environmental exposure on newborns allergy risk; prospective mother-child-cohort) and of the LISA cohort study (Multicenter prospective German cohort on lifestyle factors, immune system development and allergy)
since 2008
Head of the research group “Environmental immune cell regulation” at the Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology and Core Facility Studies
since 2004
Senior Scientist at the Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology and Core Facility Studies (Dr. Irina Lehmann), responsible for the coordination of blood sampling and analysis of immune parameters in the prospective birth cohort studies of the department
Research interest: modulation of immune responses by environmental factors and the impact on allergic outcomes in birth cohort studies
2001 – 2003
Postdoc at the company “metaGen Pharmaceuticals”, Department of Cell Biology, Berlin. Project leader, responsible for validation of new tumour targets at cellular level
2001
Postdoc at the Institute „Deutsches Rheuma-Forschungszentrum”, Berlin. Topic: „Characterisation of autoantigen-specific T cells”
1997 - 2001
PhD Student at the Department of Dermatology, University Hospital Charité and Technical University, Berlin
PhD thesis: „Analysis of tumour-specific T cells in melanoma patients with immune therapy“, degree: Dr.rer.nat.
1996 - 1997
Scientific assistant at the University Hospital Charité, Berlin. Topic: „Generation of reactive oxygen species in tumour cells after treatment with cytokines“
1993
Awarded a Fellowship of the German academic exchange service (DAAD) to study genetics at University of Turku and Oulu, Finnland
Diploma thesis: „Catalase, myeloperoxidase and hydrogen peroxide activity in cystic fibrosis“
1990 - 1996
Student of Biology, University of Mainz and Tuebingen, Germany
Publications
Index:
- 2025 (3)
- 2024 (10)
- 2023 (12)
- 2022 (13)
- 2021 (9)
- 2020 (10)
- 2019 (9)
- 2017 (4)
- 2016 (6)
- 2015 (4)
- 2014 (5)
- 2013 (4)
- 2012 (11)
- 2011 (3)
- 2010 (11)
- 2009 (3)
- 2008 (4)
- 2007 (4)
- 2006 (3)
- 2005 (3)
- 2004 (1)
- 2003 (1)
- 2001 (1)
- 2000 (5)
You could use our publication index for further requests.
2025 (3)
- Gómez-Olarte, S., Röder, S., Rolle-Kampczyk, U., Sack, U., von Bergen, M., Borte, M., Zenclussen, A.C., Herberth, G. (2025):
Prenatal exposure to mixtures of phthalates and bisphenol A and eczema risk: findings in atopic and non-atopic children from the LiNA birth cohort
Environ. Res. 278 , art. 121667 10.1016/j.envres.2025.121667 - Meijer, M., Klein, M., Camaraschi, D., Clark, S.L., Cosin-Tomas, M., Koen, N., Lu, X., Mulder, R.H., Röder, S.W., Zhang, Y., Zilich, L., Bustamente, M., Deuschle, M., Felix, J.F., Gonzáles, J.R., Gražulevičiene, R., Streit, F., Wright, J., Carracedo, A., Cecil, C.A.M., Corpeleijn, E., Hartman, C., Herberth, G., Huels, A., Relton, C., Snieder, H., Stein, D.J., Sunyer, J., Witt, S.H., Zar, H.J., Zenclussen, A.C., Franke, B., Copeland, W., Aberg, K.A., van den Oort, E.J.C.G. (2025):
Cell type-specific methylome-wide association studies of childhood ADHD symptoms
medRxiv 10.1101/2025.04.16.25325956 - Neumann, A., Sammallahti, S., Cosin-Tomas, M., Reese, S.E., Suderman, M., Alemany, S., Almqvist, C., Andrusaityte, S., Arshad, S.H., Bakermans-Kranenburg, M.J., Beilin, L., Breton, C., Bustamante, M., Czamara, D., Dabelea, D., Eng, C., Eskenazi, B., Fuemmeler, B.F., Gilliland, F.D., Grazuleviciene, R., Håberg, S.E., Herberth, G., Holland, N., Hough, A., Hu, D., Huen, K., Hüls, A., Jarvelin, M.-R., Jin, J., Julvez, J., Koletzko, B.V., Koppelman, G.H., Kull, I., Lu, X., Maitre, L., Mason, D., Melén, E., Merid, S.K., Molloy, P.L., Mori, T.A., Mulder, R.H., Page, C.M., Richmond, R.C., Röder, S., Ross, J.P., Schellhas, L., Sebert, S., Sheppard, D., Snieder, H., Starling, A.P., Stein, D.J., Tindula, G., van IJzendoorn, M.H., Vonk, J., Walton, E., Witonsky, J., Xu, C.-J., Yang, I.V., Yousefi, P.D., Zar, H.J., Zenclussen, A.C., Zhang, H., Tiemeier, H., London, S.J., Felix, J.F., Cecil, C. (2025):
Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium
Genome Med. 17 , art. 39 10.1186/s13073-025-01451-7
2024 (10)
- Braun, G., Herberth, G., Krauss, M., König, M., Wojtysiak, N., Zenclussen, A.C., Escher, B.I. (2024):
Neurotoxic mixture effects of chemicals extracted from blood of pregnant women
Science 386 (6719), 301 - 309 10.1126/science.adq0336 - Choudhary, P., Monasso, G.S., Karhunen, V., Ronkainen, J., Mancano, G., Howe, C.G., Röder, S., Zenclussen, A.C., Herberth, G., Sebert, S., et al. (2024):
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Mol. Psychiatr. 29 , 348 - 358 10.1038/s41380-023-02331-5 - Eijkemans, M., Mommers, M., Harskamp-van Ginkel, M.W., Vrijkotte, T.G.M., Ludvigsson, J., Faresjö, Å., Bergström, A., Herberth, G., Standl, M., et al. (2024):
Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis
BMJ Open Respir. Res. 11 , e001630 10.1136/bmjresp-2023-001630 - Fischer, F., Pierzchalski, A., Riesbeck, S., Aldehoff, A.S., Castañeda-Monsalve, V., Haange, S.-B., von Bergen, M., Rolle-Kampczyk, U.E., Jehmlich, N., Zenclussen, A.C., Herberth, G. (2024):
An in vitro model system for testing chemical effects on microbiome-immune interactions - examples with BPX and PFAS mixtures
Front. Immunol. 15 , art. 1298971 10.3389/fimmu.2024.1298971 - Huber, C., Brack, W., Röder, S., von Bergen, M., Rolle-Kampczyk, U., Zenclussen, A.C., Krauss, M., Herberth, G. (2024):
Pesticide residues and polyphenols in urine – A combined LC-HRMS screening to reveal intake patterns
Environ. Int. 191 , art. 108981 10.1016/j.envint.2024.108981 - Krause, J.L., Engelmann, B., Schaepe, S.S., Rolle-Kampczyk, U., Jehmlich, N., Chang, H.-D., Slanina, U., Hoffmann, M., Lehmann, J., Zenclussen, A.C., Herberth, G., von Bergen, M., Haange, S.-B. (2024):
DSS treatment does not affect murine colonic microbiota in absence of the host
Gut Microbes 16 (1), art. 2297831 10.1080/19490976.2023.2297831 - Li, S., Spitz, N., Ghantous, A., Abrishamcar, S., Reimann, B., Marques, I., Silver, M.J., Aguilar-Lacasaña, S., Kitaba, N., Rezwan, F.I., Röder, S., Sirignano, L., Tuhkanen, J., Mancano, G., Sharp, G.C., Metayer, C., Morimoto, L., Stein, D.J., Zar, H.J., Alfano, R., Nawrot, T., Wang, C., Kajantie, E., Keikkala, E., Mustaniemi, S., Ronkainen, J., Sebert, S., Silva, W., Vääräsmäki, M., Jaddoe, V.W.V., Bernstein, R.M., Prentice, A.M., Cosin-Tomas, M., Dwyer, T., Håberg, S.E., Herceg, Z., Magnus, M.C., Munthe-Kaas, M.C., Page, C.M., Völker, M., Gilles, M., Send, T., Witt, S., Zillich, L., Gagliardi, L., Richiardi, L., Czamara, D., Räikkönen, K., Chatzi, L., Vafeiadi, M., Arshad, S.H., Ewart, S., Plusquin, M., Felix, J.F., Moore, S.E., Vrijheid, M., Holloway, J.W., Karmaus, W., Herberth, G., Zenclussen, A., Streit, F., Lahti, J., Hüls, A., Hoang, T.T., London, S.J., Wiemels, J.L. (2024):
A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation
Commun. Biol. 7 , art. 66 10.1038/s42003-023-05698-x - Maddalon, A., Pierzchalski, A., Krause, J.L., Bauer, M., Finckh, S., Brack, W., Zenclussen, A.C., Marinovich, M., Corsini, E., Krauss, M., Herberth, G. (2024):
Impact of chemical mixtures from wastewater treatment plant effluents on human immune cell activation: An effect-based analysis
Sci. Total Environ. 906 , art. 167495 10.1016/j.scitotenv.2023.167495 - Pierzchalski, A., Zenclussen, A.C., Herberth, G. (2024):
A comprehensive battery of flow cytometric immunoassays for the in vitro testing of chemical effects in human blood cells
Front. Immunol. 14 , art. 1327960 10.3389/fimmu.2023.1327960 - Wang, S., Casey, E., Sordillo, J., Aguilar-Lacasaña, S., Morales Berstein, F., Biedrzycki, R.J., Brescianini, S., Chen, S., Hough, A., Isaevska, E., Kim, W.J., Lecorguillé, M., Shaobo Li, S., Page, C.M., Park, J., Röder, S., Salontaji, K., Santorelli, G., Sun, Y., Won, S., Zillich, E., Zillich, L., Annesi-Maesano, I., Arshad, S.H., Bustamante, M., Cecil, C.A.M., Elliott, H.R., Ewart, S., Felix, J.F., Gagliardi, L., Håberg, S.E., Herberth, G., Heude, B., Holloway, J.W., Huels, A., Karmaus, W., Koppelman, G.H., London, S.J., Mumford, S.L., Nisticò, L., Popovic, M., Rusconi, F., Schisterman, E.F., Stein, D.J., Send, T., Tiemeier, H., Vonk, J.M., Vrijheid, M., Wiemels, J.L., Witt, S.H., Wright, J., Yeung, E.H., Zar, H.J., Zenclussen, A.C., Zhang, H., Chavarro, J.E., Hivert, M.-F. (2024):
Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium
Sci. Adv. 10 (48), eadr2084 10.1126/sciadv.adr2084
2023 (12)
- Kadalayil, L., Alam, M., White, C.H., Ghantous, A., Walton, E., Gruzieva, O., Merid, S.K., Kumar, A., Roy, R., Solomon, O., Huen, K., Eskenazi, B., Rzehak, P., Grote, V., Langhendries, J.-P., Verduci, E., Ferre, N., Gruszfeld, D., Gao, L., Guan, W., Zeng, X., Schisterman, E.F., Dou, J., Bakulski, K.M., Feinberg, J.I., Soomro, M.H., Pesce, G., Baiz, N., Isaevska, E., Plusquin, M., Vafeiadi, M., Roumeliotaki, T., Langie, S.A.S., Standaert, A., Allard, C., Perron, P., Bouchard, L., van Meel, E.R., Felix, J.F., Jaddoe, V.W.V., Yousefi, P.D., Ramlau‑Hansen, C.H., Relton, C.L., Tobi, E.W., Starling, A.P., Yang, I.V., Llambrich, M., Santorelli, G., Lepeule, J., Salas, L.A., Bustamante, M., Ewart, S.L., Zhang, H., Karmaus, W., Röder, S., Zenclussen, A.C., Jin, J., Nystad, W., Page, C.M., Magnus, M., Jima, D.D., Hoyo, C., Maguire, R.L., Kvist, T., Czamara, D., Räikkönen, K., Gong, T., Ullemar, V., Rifas‐Shiman, S.L., Oken, E., Almqvist, C., Karlsson, R., Lahti, J., Murphy, S.K., Håberg, S.E., London, S., Herberth, G., Arshad, H., Sunyer, J., Grazuleviciene, R., Dabelea, D., Steegers‑Theunissen, R.P.M., Nohr, E.A., Sørensen, T.I.A., Duijts, L., Hivert, M.-F., Nelen, V., Popovic, M., Kogevinas, M., Nawrot, T.S., Herceg, Z., Annesi-Maesano, I., Fallin, M.D., Yeung, E., Breton, C.V., Koletzko, B., Holland, N., Melén, E., Sharp, G.C., Silver, M.J., Rezwan, F.I., Holloway, J.H. (2023):
Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude
Clin. Epigenetics 15 , art. 148 10.1186/s13148-023-01542-5 - Kilanowski, A., Thiering, E., Wang, G., Kumar, A., Kress, S., Flexeder, C., Bauer, C.-P., Berdel, D., von Berg, A., Bergström, A., Gappa, M., Heinrich, J., Herberth, G., Koletzko, S., Kull, I., Melen, E., Schikowski, T., Peters, A., Standl, M. (2023):
Allergic disease trajectories up to adolescence: Characteristics, early-life, and genetic determinants
Allergy 78 (3), 836 - 850 10.1111/all.15511 - Kotsakis Ruehlmann, A., Sammallahti, S., Cortés Hidalgo, A.P., Bakulski, K.M., Binder, E.B., Campbell, M.L., Caramaschi, D., Cecil, C., Colicino, E., Cruceanu, C., Czamara, D., Dieckmann, L., Dou, J., Felix, J.F., Frank, J., Håberg, S.E., Herberth, G., Hoang, T.T., Houtepen, L.C., Hüls, A., Koen, N., London, S.J., Magnus, M.C., Mancano, G., Mulder, R.H., Page, C.M., Räikkönen, K., Röder, S., Schmidt, R.J., Send, T.S., Sharp, G., Stein, D.J., Streit, F., Tuhkanen, J., Witt, S.H., Zar, H.J., Zenclussen, A.C., Zhang, Y., Zillich, L., Wright, R., Lahti, J., Brunst, K.J. (2023):
Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation
Mol. Psychiatr. 28 , 5090 - 5100 10.1038/s41380-023-02010-5 - Krause, J.L., Pierzchalski, A., Chang, H.D., Zenclussen, A.C., Bauer, M., Herberth, G. (2023):
Bisphenols, but not phthalate esters, modulate gene expression in activated human MAIT cells in vitro
Toxicol. Rep. 10 , 348 - 356 10.1016/j.toxrep.2023.02.017 - Maddalon, A., Pierzchalski, A., Kretschmer, T., Bauer, M., Zenclussen, A.C., Marinovich, M., Corsini, E., Herberth, G. (2023):
Mixtures of per- and poly-fluoroalkyl substances (PFAS) reduce the in vitro activation of human T cells and basophils
Chemosphere 336 , art. 139204 10.1016/j.chemosphere.2023.139204 - Musiol, S., Harris, C.P., Karlina, R., Gostner, J.M., Rathkolb, B., Schnautz, B., Schneider, E., Mair, L., Elorduy Vergara, E., Flexeder, C., Koletzko, S., Bauer, C.-P., Schikowski, T., Berdel, D., von Berg, A., Herberth, G., Rozman, J., Hrabe de Angelis, M., Standl, M., Schmidt-Weber, C.B.., Ussar, S., Alessandrini, F. (2023):
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice
Allergy 78 (5), 1218 - 1233 10.1111/all.15589 - Pfannes, R., Pierzchalski, A., Maddalon, A., Simion, A., Zouboulis, C.C., Behre, G., Zenclussen, A.C., Westphal, S., Fest, S., Herberth, G. (2023):
Characterization of post-vaccination SARS-CoV-2 T cell subtypes in patients with different hematologic malignancies and treatments
Front. Immunol. 14 , art. 1087996 10.3389/fimmu.2023.1087996 - Pierzchalski, A., Zenclussen, A.C., Herberth, G. (2023):
OMIP-94: Twenty-four-color (thirty-marker) panel for deep immunophenotyping of immune cells in human peripheral blood
Cytom. Part A 103 (9), 695 - 702 10.1002/cyto.a.24766 - Thiering, E., Markevych, I., Kress, S., Astell-Burt, T., Feng, X., Altug, H., Koletzko, S., Bauer, C.-P., von Berg, A., Berdel, D., Herberth, G., Schikowski, T., Heinrich, J., Standl, M. (2023):
Gene-environment interaction in the association of residential greenness and 25(OH) vitamin D
Environ. Pollut. 327 , art. 121519 10.1016/j.envpol.2023.121519 - Thürmann, L., Bauer, M., Ferland, M., Messingschlager, M., Schikowski, T., von Berg, A., Heinrich, J., Herberth, G., Lehmann, I., Standl, M., Trump, S. (2023):
Undiagnosed pediatric elevated blood pressure is characterized by induction of proinflammatory and cytotoxic mediators
Hypertension 80 (11), 2425 - 2436 10.1161/HYPERTENSIONAHA.123.21489 - Thürmann, L., Klös, M., Mackowiak, S.D., Bieg, M., Bauer, T., Ishaque, N., Messingschlager, M., Herrmann, C., Röder, S., Bauer, M., Schäuble, S., Faessler, E., Hahn, U., Weichenhan, D., Mücke, O., Plass, C., Borte, M., von Mutius, E., Stangl, G.I., Lauener, R., Karvonen, A.M., Divaret-Chauveau, A., Riedler, J., Heinrich, J., Standl, M., von Berg, A., Schaaf, B., Herberth, G., Kabesch, M., Eils, R., Trump, S., Lehmann, I. (2023):
Global hypomethylation in childhood asthma identified by genome-wide DNA-methylation sequencing preferentially affects enhancer regions
Allergy 78 (6), 1489 - 1506 10.1111/all.15658 - Wang, M., Flexeder, C., Kilanowski, A., Kress, S., Herberth, G., Schikowski, T., Peters, A., Standl, M. (2023):
Changes in sleep duration and sleep difficulties from adolescence to young adulthood and the risk of obesity: Bidirectional evidence in the GINIplus and LISA studies
Sleep Med. 101 , 401 - 410 10.1016/j.sleep.2022.11.031
2022 (13)
- Amici, F., Röder, S., Kiess, W., Borte, M., Zenclussen, A.C., Widdig, A., Herberth, G. (2022):
Maternal stress, child behavior and the promotive role of older siblings
BMC Public Health 22 , art. 863 10.1186/s12889-022-13261-2 - Greimel, E., Adams, L., Zsigo, C., Berdel, D., von Berg, A., Koletzko, S., Bauer, C.-P., Schikowski, T., Herberth, G., Heinrich, J., Schulte-Körne, G., Standl, M. (2022):
Psychopathological symptoms as precursors of depressive symptoms in adolescence: a prospective analysis of the GINIplus and LISA birth cohort studies
Soc. Psychiatry Psychiatr. Epidemiol. 57 (8), 1627 - 1639 10.1007/s00127-022-02267-1 - Junge, K.M., Buchenauer, L., Strunz, S., Seiwert, B., Thürmann, L., Rolle-Kampczyk, U.E., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Zenclussen, A.C., Schöneberg, T., Stangl, G.I., Herberth, G., Lehmann, I., Reemtsma, T., Polte, T. (2022):
Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study
Sci. Total Environ. 814 , art. 152676 10.1016/j.scitotenv.2021.152676 - Kempf, E., Landgraf, K., Stein, R., Hanschkow, M., Hilbert, A., Abou Jamra, R., Boczki, P., Herberth, G., Kühnapfel, A., Tseng, Y.-H., Stäubert, C., Schöneberg, T., Kühnen, P., Rayner, N.W., Zeggini, E., Kiess, W., Blüher, M., Körner, A. (2022):
Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity
Nat. Metab. 4 , 1697 - 1712 10.1038/s42255-022-00703-9 - Krause, J.L., Engelmann, B., Nunes da Rocha, U., Pierzchalski, A., Chang, H.D., Zenclussen, A.C., von Bergen, M., Rolle-Kampczyk, U., Herberth, G. (2022):
MAIT cell activation is reduced by direct and microbiota-mediated exposure to bisphenols
Environ. Int. 158 , art. 106985 10.1016/j.envint.2021.106985 - Marb, A., Libuda, L., Standl, M., Koletzko, S., Bauer, C.-P., Schikowski, T., Berdel, D., von Berg, A., Herberth, G., Bühlmeier, J., Harris, C.P. (2022):
Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies
Eur. J. Clin. Nutr. 76 , 1478 - 1485 10.1038/s41430-022-01125-2 - Markevych, I., Astell-Burt, T., Altug, H., Triebner, K., Standl, M., Flexeder, C., Heinrich, J., Schikowski, T., Koletzko, S., Herberth, G., Bauer, C.-P., von Berg, A., Berdel, D., Feng, X. (2022):
Residential green space and age at menarche in German and Australian adolescent girls: A longitudinal study
Int. J. Hyg. Environ. Health. 240 , art. 113917 10.1016/j.ijheh.2021.113917 - Meijer, M., Klein, M., Caramaschi, D., Mulder, R., Cosin, M., Lu, X., Zhang, Y., Röder, S., Zilich, L., Huels, A., Hartman, C., Snieder, H., Bustamante, M., Herberth, G., Franke, B., Copeland, B., Aberg, K., van den Oord, E. (2022):
Meta-analysis of cell type-sSpecific DNA methylation of childhood attention-deficit/hyperactivity disorder symptoms
Biol. Psychiatry 91 (9 (Suppl.)), S111 - S112 10.1016/j.biopsych.2022.02.294 - Röder, S., Herberth, G., Zenclussen, A.C., Bauer, M. (2022):
EpiVisR: exploratory data analysis and visualization in epigenome-wide association analyses
BMC Bioinformatics 23 , art. 292 10.1186/s12859-022-04836-2 - Sammallahti, S., Koopman‑Verhoeff, M.E., Binter, A.-C., Mulder, R.H., Cabré‑Riera, A., Kvist, T., Malmberg, A.L.K., Pesce, G., Plancoulaine, S., Heiss, J.A., Rifas‐Shiman, S.L., Röder, S.W., Starling, A.P., Wilson, R., Guerlich, K., Haftorn, K.L., Page, C.M., Luik, A.I., Tiemeier, H., Felix, J.F., Raikkonen, K., Lahti, J., Relton, C.L., Sharp, G.C., Waldenberger, M., Grote, V., Heude, B., Annesi-Maesano, I., Hivert, M.-F., Zenclussen, A.C., Herberth, G., Dabelea, D., Grazuleviciene, R., Vafeiadi, M., Håberg, S.E., London, S.J., Guxens, M., Richmond, R.C., Cecil, C.A.M. (2022):
Longitudinal associations of DNA methylation and sleep in children: a meta‑analysis
Clin. Epigenetics 14 , art. 83 10.1186/s13148-022-01298-4 - Schicketanz, J., Röder, S., Herberth, G., Kabisch, S., Lakes, T. (2022):
On foot or by car: what determines children’s active school travel?
Child. Geogr. 20 (2), 174 - 188 10.1080/14733285.2021.1921698 - Schütte, O., Bachmann, L., Shivappa, N., Hebert, J.R., Felix, J.F., Röder, S.W., Sack, U., Borte, M., Kiess, W., Zenclussen, A.C., Stangl, G.I., Herberth, G., Junge, K.M. (2022):
Pro-inflammatory diet pictured in children with atopic dermatitis or food allergy: nutritional data of the LiNA cohort
Front. Nutr. 9 , art. 868872 10.3389/fnut.2022.868872 - Wang, J., Tischer, C., Standl, M., Weidinger, S., von Berg, A., Herberth, G., Yew, Y.W., Heinrich, J., Schmitt, J., Apfelbacher, C. (2022):
Lifetime prevalence and determinants of hand eczema in an adolescent population in Germany: 15-year follow-up of the LISA cohort study
J. Eur. Acad. Dermatol. Venereol. 36 (4), 547 - 556 10.1111/jdv.17814
2021 (9)
- Harris, C.P., Fuertes, E., Koletzko, S., von Berg, A., Berdel, D., Schikowski, T., Herberth, G., Bauer, C.-P., Schulz, H., Jarvis, D., Standl, M. (2021):
Modification of the association of dietary PUFA with lung function by FADS gene variants in adolescents: results from the GINIplus and LISA birth cohorts
Thorax 76 (Suppl. 1), A51 10.1136/thorax-2020-BTSabstracts.89 - Hyytiäinen, H., Kirjavainen, P.V., Täubel, M., Tuoresmäki, P., Casas, L., Heinrich, J., Herberth, G., Strandl, M., Renz, H., Piippo-Savolainen, E., Hyvärinen, A., Pekkanen, J., Karvonen, A.M. (2021):
Microbial diversity in homes and the risk of allergic rhinitis and inhalant atopy in two European birth cohorts
Environ. Res. 196 , art. 110835 10.1016/j.envres.2021.110835 - Junge, K.M., Buchenauer, L., Elter, E., Butter, K., Kohajda, T., Herberth, G., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Rolle-Kampczyk, U.E., Lehmann, I., Gminski, R., Ohlmeyer, M., Polte, T. (2021):
Wood emissions and asthma development: Results from an experimental mouse model and a prospective cohort study
Environ. Int. 151 , art. 106449 10.1016/j.envint.2021.106449 - Kasmanas, J.C., Bartholomäus, A., Borim Corrêa, F., Tal, T., Jehmlich, N., Herberth, G., von Bergen, M., Stadler, P.F., de Carvalho, A.C.P.L.F., Nunes da Rocha, U. (2021):
HumanMetagenomeDB: a public repository of curated and standardized metadata for human metagenomes
Nucleic Acids Res. 49 (D1), D743 - D750 10.1093/nar/gkaa1031 - Kilanowski, A., Thiering, E., Kress, S., Wang, G., Kumar, A., Schikowski, T., Berdel, D., von Berg, A., Bauer, C., Koletzko, S., Heinrich, J., Herberth, G., Melén, E., Peters, A., Standl, M. (2021):
Developmental clusters of allergic diseases: Early-life risk factors, characteristics and genetic effects
Allergy 76 (S110), 406 - 407 10.1111/all.15095 - Luo, M., Meehan, A.J., Walton, E., Röder, S., Herberth, G., Zenclussen, A.C., Cosín-Tomás, M., Sunyer, J., Mulder, R.H., Cortes Hidalgo, A.P., Bakermans-Kranenburg, M.J., Felix, J.F., Relton, C., Suderman, M., Pappa, I., Kok, R., Tiemeier, H., van IJzendoorn, M.H., Barker, E.D., Cecil, C.A.M. (2021):
Neonatal DNA methylation and childhood low prosocial behavior: An epigenome-wide association meta-analysis
Am. J. Med. Genet. B 186 (4), 228 - 241 10.1002/ajmg.b.32862 - Mäki, J.M., Kirjavainen, P.V., Täubel, M., Piippo-Savolainen, E., Backman, K., Hyvärinen, A., Tuoresmäki, P., Jayaprakash, B., Heinrich, J., Herberth, G., Standl, M., Pekkanen, J., Karvonen, A.M. (2021):
Associations between dog keeping and indoor dust microbiota
Sci. Rep. 11 , art. 5341 10.1038/s41598-021-84790-w - Pinart, M., Jeran, S., Boeing, H., Stelmach-Mardas, M., Standl, M., Schulz, H., Harris, C., von Berg, A., Herberth, G., Koletzko, S., Linseisen, J., Breuninger, T.A., Nöthlings, U., Barbaresko, J., Benda, S., Lachat, C., Yang, C., Gasparini, P., Robino, A., Rojo-Martínez, G., Castaño, L., Guillaume, M., Donneau, A.-F., Hoge, A., Gillain, N., Avraam, D., Burton, P.R., Bouwman, J., Pischon, T., Nimptsch, K. (2021):
Dietary macronutrient composition in relation to circulating HDL and non-HDL cholesterol: A federated individual-level analysis of Cross-sectional data from adolescents and adults in 8 European studies
J. Nutr. 151 (8), 2317 - 2329 10.1093/jn/nxab077 - Thürmann, L., Herberth, G., Seiwert, B., Schlittenbauer, L., Rolle-Kampczyk, U., Röder, S., Sack, U., Borte, M., von Bergen, M., Trump, S., Reemtsma, T., Lehmann, I. (2021):
Prenatal paraben exposure and atopic dermatitis-related outcomes among children
Allergy 76 (10), 3122 - 3132 10.1111/all.14890
2020 (10)
- Feng, X., Flexeder, C., Markevych, I., Standl, M., Heinrich, J., Schikowski, T., Koletzko, S., Herberth, G., Bauer, C.-P., von Berg, A., Berdel, D., Astell-Burt, T. (2020):
Impact of residential green space on sleep quality and sufficiency in children and adolescents residing in Australia and Germany
Int. J. Environ. Res. Public Health 17 (13), art. 4894 10.3390/ijerph17134894 - Fritz-Wallace, K., Engelmann, B., Krause, J.L., Schäpe, S.S., Pöppe, J., Herberth, G., Rösler, U., Jehmlich, N., von Bergen, M., Rolle-Kampczyk, U. (2020):
Quantification of glyphosate and AMPA from microbiome reactor fluids
Rapid Commun. Mass Spectrom. 34 (7), e8668 10.1002/rcm.8668 - Krause, J.L., Haange, S.-B., Schäpe, S.S., Engelmann, B., Rolle-Kampczyk, U., Fritz-Wallace, K., Wang, Z., Jehmlich, N., Türkowsky, D., Schubert, K., Pöppe, J., Bote, K., Rösler, U., Herberth, G., von Bergen, M. (2020):
The glyphosate formulation Roundup® LB plus influences the global metabolome of pig gut microbiota in vitro
Sci. Total Environ. 745 , art. 140932 10.1016/j.scitotenv.2020.140932 - Krause, J.L., Schaepe, S.S., Fritz-Wallace, K., Engelmann, B., Rolle-Kampczyk, U., Kleinsteuber, S., Schattenberg, F., Liu, Z., Müller, S., Jehmlich, N., von Bergen, M., Herberth, G. (2020):
Following the community development of SIHUMIx – a new intestinal in vitro model for bioreactor use
Gut Microbes 11 (4), 1116 - 1129 10.1080/19490976.2019.1702431 - Krause, J.L., Schäpe, S.S., Schattenberg, F., Müller, S., Ackermann, G., Rolle-Kampczyk, U.E., Jehmlich, N., Pierzchalski, A., von Bergen, M., Herberth, G. (2020):
The activation of mucosal-associated invariant T (MAIT) cells is affected by microbial diversity and riboflavin utilization in vitro
Front. Microbiol. 11 , art. 755 10.3389/fmicb.2020.00755 - Markevych, I., Ludwig, R., Baumbach, C., Standl, M., Heinrich, J., Herberth, G., de Hoogh, K., Pritsch, K., Weikl, F. (2020):
Residing near allergenic trees can increase risk of allergies later in life: LISA Leipzig study
Environ. Res. 191 , art. 110132 10.1016/j.envres.2020.110132 - Mendler, A., Geier, F., Haange, S.-B., Pierzchalski, A., Krause, J.L., Nijenhuis, I., Froment, J., Jehmlich, N., Berger, U., Ackermann, G., Rolle-Kampczyk, U., von Bergen, M., Herberth, G. (2020):
Mucosal-associated invariant T-Cell (MAIT) activation is altered by chlorpyrifos- and glyphosate-treated commensal gut bacteria
J. Immunotoxicol. 17 (1), 10 - 20 10.1080/1547691X.2019.1706672 - Mendler, A., Pierzchalski, A., Bauer, M., Röder, S., Sattler, A., Standl, M., Borte, M., von Bergen, M., Rolle-Kampczyk, U., Herberth, G. (2020):
MAIT cell activation in adolescents is impacted by bile acid concentrations and body weight
Clin. Exp. Immunol. 200 (2), 199 - 213 10.1111/cei.13423 - Schäpe, S.S., Krause, J.L., Masanetz, R.K., Riesbeck, S., Starke, R., Rolle-Kampczyk, U., Eberlein, C., Heipieper, H.J., Herberth, G., von Bergen, M., Jehmlich, N. (2020):
Environmentally relevant concentration of bisphenol S shows slight effects on SIHUMIx
Microorganisms 8 (9), art. 1436 10.3390/microorganisms8091436 - Thyssen, J.P., Ahluwalia, T.S., Paternoster, L., Ballardini, N., Bergström, A., Melén, E., Chawes, B.L., Stokholm, J., Hourihane, J.O., O'Sullivan, D.M., Bager, P., Melbye, M., Bustamante, M., Torrent, M., Esplugues, A., Duijts, L., Hu, C., Elbert, N.J., Pasmans, S.G.M.A., Nijsten, T.E.C., von Berg, A., Standl, M., Schikowski, T., Herberth, G., Heinrich, J., Lee, Y.-A., Marenholz, I., Lau, S., Curtin, J.A., Simpson, A., Custovic, A., Pennell, C.E., Wang, C.A., Holt, P.G., Bisgaard, H., Bønnelykke, K. (2020):
Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis. Letter to the editor
Allergy 75 (6), 1481 - 1485 10.1111/all.14162
2019 (9)
- Bauer, M., Hackermüller, J., Schor, J., Schreiber, S., Fink, B., Pierzchalski, A., Herberth, G. (2019):
Specific induction of the unique GPR15 expression in heterogeneous blood lymphocytes by tobacco smoking
Biomarkers 24 (3), 217 - 224 10.1080/1354750X.2018.1539769 - Klös, M., Thürmann, L., Bauer, M., Heinrich, J., Standl, M., von Berg, A., Schaaf, B., Weichenhan, D., Mücke, O., Plass, C., Röder, S., Herberth, G., Sack, U., Borte, M., Stangl, G.I., Eils, R., Trump, S., Lehmann, I. (2019):
Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze
Allergy 74 (10), 2002 - 2006 10.1111/all.13837 - Mäki, J., Kirjavainen, P., Täubel, M., Remes, S., Hyvärinen, A., Heinrich, J., Herberth, G., Standl, M., Pekkanen, J., Karvonen, A. (2019):
Influence of dog keeping on indoor dust microbiota
Allergy 74 (Suppl. 106), 849 - 849 10.1111/all.13961 - Markevych, I., Feng, X., Astell-Burt, T., Standl, M., Sugiri, D., Schikowski, T., Koletzko, S., Herberth, G., Bauer, C.-P., von Berg, A., Berdel, D., Heinrich, J. (2019):
Residential and school greenspace and academic performance: Evidence from the GINIplus and LISA longitudinal studies of German adolescents
Environ. Pollut. 245 , 71 - 76 10.1016/j.envpol.2018.10.053 - Ordiz, M.I., Semba, R.D., Moaddel, R., Rolle-Kampczyk, U., von Bergen, M., Herberth, G., Khadeer, M., Röder, S., Manary, M.J. (2019):
Serum amino acid concentrations in infants from Malawi are associated with linear growth
Curr. Dev. Nutr. 3 (10), nzz100 10.1093/cdn/nzz100 - Sattler, A., Thiel, L.G., Ruhm, A.H., Souidi, N., Seifert, M., Herberth, G., Kotsch, K. (2019):
The TL1A-DR3 axis selectively drives effector functions in human MAIT cells
J. Immunol. 203 (11), 2970 - 2978 10.4049/jimmunol.1900465 - Schäpe, S.S., Krause, J.L., Engelmann, B., Fritz-Wallace, K., Schattenberg, F., Liu, Z., Müller, S., Jehmlich, N., Rolle-Kampczyk, U., Herberth, G., von Bergen, M. (2019):
The simplified human intestinal microbiota (SIHUMIx) shows high structural and functional resistance against changing transit times in in vitro bioreactors
Microorganisms 7 (12), art. 641 10.3390/microorganisms7120641 - Thürmann, L., Herberth, G., Rolle-Kampczyk, U., Röder, S., Borte, M., von Bergen, M., Lehmann, I., Trump, S. (2019):
Elevated gestational IL-13 during fetal development is associated with hyperactivity and inattention in eight-year-old children
Front. Immunol. 10 , art. 1658 10.3389/fimmu.2019.01658 - Yang, B.-Y., Markevych, I., Harris, C., Standl, M., Schikowski, T., Koletzko, S., Herberth, G., Bauer, C.-P., von Berg, A., Berdel, D., Dong, G.-H., Heinrich, J. (2019):
High-sensitivity C-reactive protein and allergic endpoints in German adolescents
Int. Arch. Allergy Immunol. 179 , 152 - 157 10.1159/000497320
2017 (4)
- Englich, B., Herberth, G., Rolle-Kampczyk, U., Trump, S., Röder, S., Borte, M., Stangl, G.I., von Bergen, M., Lehmann, I., Junge, K.M. (2017):
Maternal cytokine status may prime the metabolic profile and increase risk of obesity in children
Int. J. Obes. 41 (9), 1440 - 1446 10.1038/ijo.2017.113 - Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F. (2017):
From the exposome to mechanistic understanding of chemical-induced adverse effects
Environ. Int. 99 , 97 - 106 10.1016/j.envint.2016.11.029 - Herberth, G., Pierzchalski, A., Feltens, R., Bauer, M., Röder, S., Olek, S., Hinz, D., Borte, M., von Bergen, M., Lehmann, I. (2017):
Prenatal phthalate exposure associates with low regulatory T-cell numbers and atopic dermatitis in early childhood: Results from the LINA mother-child study. Letter to the editor
J. Allergy Clin. Immunol. 139 (4), 1376 - 1379.e8 10.1016/j.jaci.2016.09.034 - Winter, M., Thürmann, L., Gu, Z., Schüürmann, G., Herberth, G., Hinz, D., von Bergen, M., Harms, H., Olek, S., Röder, S., Borte, M., Eils, R., Lehmann, I., Trump, S. (2017):
The benzene metabolite 1,4-benzoquinone reduces regulatory T-cell function: A potential mechanism for tobacco smoke–associated atopic dermatitis
J. Allergy Clin. Immunol. 140 (2), 603 - 605 10.1016/j.jaci.2017.01.034
2016 (6)
- Bauer, M., Fink, B., Thürmann, L., Eszlinger, M., Herberth, G., Lehmann, I. (2016):
Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation
Clin. Epigenetics 8 , art. 83 10.1186/s13148-016-0249-7 - Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J.-P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K.M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R., Lehmann, I. (2016):
Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
Mol. Syst. Biol. 12 (3), art. 861 10.15252/msb.20156520 - Hörnig, F., Kohajda, T., Röder, S., Herberth, G., von Bergen, M., Borte, M., Diez, U., Rolle-Kampczyk, U., Simon, J.-C., Denburg, J.A., Lehmann, I., Junge, K.M. (2016):
The LINA study: higher sensitivity of infant compared to maternal eosinophil/basophil progenitors to indoor chemical exposures
J. Environ. Public Health 2016 , art. 5293932 10.1155/2016/5293932 - Junge, K.M., Bauer, T., Geissler, S., Hirche, F., Thürmann, L., Bauer, M., Trump, S., Bieg, M., Weichenhan, D., Gu, L., Mallm, J.-P., Ishaque, N., Mücke, O., Röder, S., Herberth, G., Diez, U., Borte, M., Rippe, K., Plass, C., Hermann, C., Stangl, G.I., Eils, R., Lehmann, I. (2016):
Increased vitamin D levels at birth and in early infancy increase offspring allergy risk—evidence for involvement of epigenetic mechanisms. Letter to the editor
J. Allergy Clin. Immunol. 137 (2), 610 - 613 10.1016/j.jaci.2015.06.040 - Schreier, M., Schwartze, J.T., Landgraf, K., Scheuermann, K., Erbs, S., Herberth, G., Pospisilik, J.A., Kratzsch, J., Kiess, W., Körner, A. (2016):
Osteopontin is BMI-independently related to early endothelial dysfunction in children
J. Clin. Endocrinol. Metab. 101 (11), 4164 - 4169 10.1210/jc.2016-2238 - Trump, S., Bieg, M., Gu, Z., Thürmann, L., Bauer, T., Bauer, M., Ishaque, N., Röder, S., Gu, L., Herberth, G., Lawerenz, C., Borte, M., Schlesner, M., Plass, C., Diessl, N., Eszlinger, M., Mücke, O., Elvers, H.-D., Wissenbach, D.K., von Bergen, M., Herrmann, C., Weichenhan, D., Wright, R.J., Lehmann, I., Eils, R. (2016):
Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation
Sci. Rep. 6 , art. 28616 10.1038/srep28616
2015 (4)
- Bauer, M., Linsel, G., Fink, B., Offenberg, K., Hahn, A.M., Sack, U., Knaack, H., Eszlinger, M., Herberth, G. (2015):
A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood
Clin. Epigenetics 7 , art. 81 10.1186/s13148-015-0113-1 - Bauer, M., Linsel, G., Offenberg, K., Sack, U., Knaak, H., Herberth, G. (2015):
Tobacco smoking induces specifically the expansion of a subpopulation of T cells expressing the homing and HIV co-receptor GPR15
Toxicol. Lett. 238 (2, Suppl.), S105 10.1016/j.toxlet.2015.08.344 - Herberth, G., Offenberg, K., Rolle-Kampczyk, U., Bauer, M., Otto, W., Röder, S., Grützmann, K., Sack, E., Simon, J.-C., Borte, M., von Bergen, M., Lehmann, I. (2015):
Endogenous metabolites and inflammasome activity in early childhood and links to respiratory diseases
J. Allergy Clin. Immunol. 136 (2), 495 - 497 10.1016/j.jaci.2015.01.022 - Klümper, C., Krämer, U., Lehmann, I., von Berg, A., Berdel, D., Herberth, G., Beckmann, C., Link, E., Heinrich, J., Hoffmann, B., Schins, R.P.F. (2015):
Air pollution and cytokine responsiveness in asthmatic and non-asthmatic children
Environ. Res. 138 , 381 - 390 10.1016/j.envres.2015.02.034
2014 (5)
- Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I. (2014):
Prenatal VOC exposure and redecoration are related to wheezing in early infancy
Environ. Int. 73 , 393 - 401 10.1016/j.envint.2014.08.013 - Gasch, M., Goroll, T., Bauer, M., Hinz, D., Schütze, N., Polte, T., Kesper, D., Simon, J.-C., Hackermüller, J., Lehmann, I., Herberth, G. (2014):
Generation of IL-8 and IL-9 producing CD4+ T cells is affected by Th17 polarizing conditions and AHR ligands
Mediat. Inflamm. 2014 , art. 182549 10.1155/2014/182549 - Herberth, G. (2014):
LARS, LISA und LINA – was lehren die Leipziger Allergierisiko-Studien?
Allergologie 37 (4), 157 - 157 10.5414/ALX01666 - Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Sack, U., Borte, M., Lehmann, I. (2014):
Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
J. Allergy Clin. Immunol. 133 (2), 543 - 550.e4 10.1016/j.jaci.2013.06.036 - Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I. (2014):
The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
Clin. Immunol. 152 (1-2), 68 - 76 10.1016/j.clim.2014.02.013
2013 (4)
- Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen-Tomm, M., Sack, U., Borte, M., Lehmann, I. (2013):
Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and with low Treg numbers
Allergy 68 (Suppl. 97), 628 - 628 10.1111/all.12252 - Herberth, G., Herzog, T., Hinz, D., Röder, S., Schilde, M., Sack, U., Diez, U., Borte, M., Lehmann, I. (2013):
Renovation activities during pregnancy induce a Th2 shift in fetal but not in maternal immune system
Int. J. Hyg. Environ. Health. 216 (3), 309 - 316 10.1016/j.ijheh.2012.06.002 - Weisse, K., Herberth, G., Röder, S., Borte, M., Heroux, D., Denburg, J., Lehmann, I. (2013):
Eosinophil/basophil (Eo/B) progenitors in cord blood (CB) predict respiratory outcomes in early infancy
Allergy 68 (Suppl. 97), 53 - 53 10.1111/all.12247 - Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I. (2013):
Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
Allergy 68 (2), 220 - 228 10.1111/all.12081
2012 (11)
- Herberth, G., Hinz, D., Bauer, M., Röder, S., Olek, S., Huehn, J., Sack, U., Borte, M., Simon, J., Lehmann, I. (2012):
Exposures during pregnancy modulate foetal regulatory T-cell development with consequences for the allergy risk of the child
Allergy 67 (Suppl. 96), 65 - 65 10.1111/all.12033 - Herberth, G., Hinz, D., Bauer, M., Röder, S., Olek, S., Hühn, J., Sack, U., Borte, M., Simon, J.C., Lehmann, I. (2012):
Environmental exposure during pregnancy modulates fetal Treg development with consequences for the allergy risk of the child
J. Immunol. 188 (Suppl.), 175.10 - Herberth, G., Hinz, D., Bauer, M., Röder, S., Olek, S., Hühn, J., Sack, U., Borte, M., Simon, J.C., Lehmann, I. (2012):
Environmental exposure during pregnancy modulates fetal Treg development with consequences for the allergy risk of the child
J. Reprod. Immunol. 94 (1), 54 - 54 10.1016/j.jri.2012.03.336 - Hinz, D., Bauer, M., Röder, S., Olek, S., Huehn, J., Sack, U., Borte, M., Simon, J.C., Herberth, G., Lehmann, I. (2012):
Lower treg number in cord blood is associated with significant increased risk against atopic dermatitis up to the second year of life
Eur. J. Epidemiol. 27 (Suppl. 1), S104 10.1007/s10654-012-9722-6 - Hinz, D., Bauer, M., Röder, S., Olek, S., Huehn, J., Sack, U., Borte, M., Simon, J.C., Lehmann, I., Herberth, G. (2012):
Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year
Allergy 67 (3), 380 - 389 10.1111/j.1398-9995.2011.02767.x - Landgraf, K., Friebe, D., Ullrich, T., Kratzsch, J., Dittrich, K., Herberth, G., Adams, V., Kiess, W., Erbs, S., Körner, A. (2012):
Chemerin as a mediator between obesity and vascular inflammation in children
J. Clin. Endocrinol. Metab. 97 (4), E556 - E564 10.1210/jc.2011-2937 - Lehmann, I., Herberth, G. (2012):
Cord blood immune status: predicting health or allergy?
Allergy 67 (4), 445 - 448 10.1111/j.1398-9995.2012.02800.x - Weisse, K., Herberth, G., Roeder, S., Borte, M., Heroux, D., Denburg, J.A., Lehmann, I. (2012):
Cord blood (CB) eosinophil/basophil (Eo/B) progenitors predict respiratory outcomes until the age of two
J. Allergy Clin. Immunol. 129 (2, Suppl.), AB118 - AB118 10.1016/j.jaci.2011.12.570 - Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J. (2012):
The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
Clin. Exp. Allergy 42 (9), 1337 - 1346 10.1111/j.1365-2222.2012.04024.x - Weisse, K., Winkler, S., Stangl, G., Hirche, F., Herberth, G., Hinz, D., Röder, S., Borte, M., Richter, T., Lehmann, I. (2012):
Maternal and newborn vitamin D status and its impact on atopy development in the German LINA cohort study
Allergy 67 (Suppl. 96), 201 - 201 10.1111/all.12035 - Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I. (2012):
Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
J. Reprod. Immunol. 94 (1), 53 - 54 10.1016/j.jri.2012.03.335
2011 (3)
- Herberth, G., Hinz, D., Röder, S., Schlink, U., Sack, U., Diez, U., Borte, M., Lehmann, I. (2011):
Maternal immune status in pregnancy: relation to offspring's immunity and allergy risk
Allergy 66 (s94), 187 10.1111/j.1398-9995.2011.02606.x - Herberth, G., Hinz, D., Röder, S., Schlink, U., Sack, U., Diez, U., Borte, M., Lehmann, I. (2011):
Maternal immune status in pregnancy is related to offspring's immune responses and atopy risk
Allergy 66 (8), 1065 - 1074 10.1111/j.1398-9995.2011.02587.x - Weisse, K., Lehmann, I., Herberth, G., Kohajda, T., Röder, S., Borte, M., Heroux, A., Denburg, J. (2011):
Circulating eosinophil/basophil (Eo/B) progenitors at one year of age positively correlate with atopic eczema and indoor chemical exposure in the LINA Study
J. Allergy Clin. Immunol. 127 (2), AB146 - AB146 10.1016/j.jaci.2010.12.581
2010 (11)
- Feltens, R., Mögel, I., Röder-Stolinski, C., Simon, J.-C., Herberth, G., Lehmann, I. (2010):
Chlorobenzene induces oxidative stress in human lung epithelial cells in vitro
Toxicol. Appl. Pharmacol. 242 (1), 100 - 108 10.1016/j.taap.2009.09.020 - Herberth, G., Daegelmann, C., Röder, S., Behrendt, H., Krämer, U., Borte, M., Heinrich, J., Herbarth, O., Lehmann, I. (2010):
IL-17E but not IL-17A is associated with allergic sensitization: results from the LISA study
Pediatr. Allergy Immunol. 21 (7), 1086 - 1090 10.1111/j.1399-3038.2010.01033.x - Herberth, G., Heinrich, J., Röder, S., Figl, A., Weiss, M., Diez, U., Borte, M., Herbarth, O., Lehmann, I. (2010):
Reduced IFN-y- and enhanced IL-4-producing CD4+ cord blood T cells are associated with a higher risk for atopic dermatitis during the first 2 yr of life
Pediatr. Allergy Immunol. 21 (1, Part-I), 5 - 13 10.1111/j.1399-3038.2009.00890.x - Herberth, G., Hinz, D., Röder, S., Schlink, U., Diez, U., Borte, M., Lehmann, I. (2010):
Innate versus adaptive immune response in newborns and their mothers: results from the LINA birth cohort study
Allergy 65 (S92), 645 - 646 10.1111/j.1398-9995.2010.02393.x - Herberth, G., Röder, S., Bockelbrink, T., Schäfer, T., Borte, M., Herbarth, O., Krämer, U., Behrendt, H., Sausenthaler, S., Heinrich, J., Lehmann, I. (2010):
Psychosozialer Stress im Kindesalter und allergische Sensibilisierung. Stressful life events in childhood and allergic sensitisation
Allergologie 33 (2), 55 - 65 10.5414/ALP34003 - Hinz, D., Simon, J.C., Maier-Simon, C., Milkova, L., Röder, S., Sack, U., Borte, M., Lehmann, I., Herberth, G. (2010):
Reduced maternal regulatory T cell numbers and increased T helper type 2 cytokine production are associated with elevated levels of immunoglobulin E in cord blood
Clin. Exp. Allergy 40 (3), 419 - 426 10.1111/j.1365-2222.2009.03434.X - Hinz, D., Simon, J., Maier-Simon, C., Milkova, L., Röder, S., Sack, U., Borte, M., Lehmann, I., Herberth, G. (2010):
The impact of maternal CD4 + CD25high T cell numbers and Th2 cytokine production during pregnancy on IgE in cord blood
Allergy 65 (S92), 315 /10.1111/j.1398-9995.2010.02393.x - Lehmann, I., Herzog, T., Hinz, D., Röder, S., Sack, U., Diez, U., Borte, M., Herberth, G. (2010):
Renovation activities during pregnancy induce a Th2 shift in the fetal but not in the maternal immune system
Allergy 65 (S92), 306 - 307 10.1111/j.1398-9995.2010.02393.x - Mögel, I., Feltens, R., Simon, J., Röder-Stolinski, C., Herberth, G., Lehmann, I. (2010):
The chlorobenzene induced inflammatory response in lung epithelial cells can be prevented by antioxidants
Allergy 65 (S92), 86 - 87 10.1111/j.1398-9995.2010.02391.x - Rzehak, P., Scherag, A., Grallert, H., Sausenthaler, S., Koletzko, S., Bauer, C.P., Schaaf, B., von Berg, A., Berdel, D., Borte, M., Herbarth, O., Krämer, U., Illig, T., Wichmann, H.-E., Hebebrand, J., Heinrich, J., Schoetzau, A., Popescu, M., Mosetter, M., Schindler, J., Franke, K., Laubereau, B., Thaqi, A., Zirngibl, A., Zutavern, A., Filipiak, B., Gehring, U., Albrecht, B., Baumgart, A., Bollrath, C., Büttner, S., Diekamp, S., Gross, I., Jakob, T., Klemke, K.K., Kurpiun, K.S., Möllermann, M., Neusüss, J., Varhelyi, A., Zorn, C., Reinhard, D., Weigand, H., Antonie, I., Bäumler-Merl, B., Tasch, C., Göhlert, R., Sönnichsen, C., Grübl, A., Bartels, P., Brockow, I., Hoffmann, U., Lötzbeyer, F., Mayrl, R., Negele, K., Schill, E.M., Wolf, B., Link, E., Sugiri, D., Ranft, U., Bolte, G., Belcredi, P., Jacob, B., Höhnke, A., Schulz, R., Sierig, G., Mirow, K., Gebauer, C., Schulze, B., Hainich, J., Sack, U., Emmrich, F., Scholten, C., Diez, U., Rehwagen, M., Schlink, U., Franck, U., Jorks, A., Röder, S., Lehmann, I., Herberth, G., Daegelmann, C., Weiss, M., Albert, M., Fahlbusch, B., Bischof, W., Koch, A., Schins, R., Ring, J., Grosch, J., Weidinger, S. (2010):
Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years
Obes. Facts 3 (3), 173 - 180 10.1159/000314612 - Rzehak, P., Thijs, C., Standl, M., Mommers, M., Glaeser, C., Jansen, E., Klopp, N., Koppelman, G.H., Singmann, P., Postma, D.S., Sausenthaler, S., Dagnelie, P.C., van den Brandt, P.A., Koletzko, B., Heinrich, J., Wichmann, H.-E., Schoetzau, A., Franke, K., Laubereau, B., Schaaf, B., Borte, M., Schulz, R., Sierig, G., Sack, U., Emmrich, F., von Berg, A., Bollrath, C., Herbarth, O., Diez, U., Lehmann, I., Herberth, G. (2010):
Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life
PLoS One 5 (10), e13261 10.1371/journal.pone.0013261
2009 (3)
- Herberth, G., Daegelmann, C., Röder, S., Behrendt, H., Kraemer, U., Borte, M., Heinrich, J., Herbarth, O., Lehmann, I. (2009):
IL-17E but not IL-17A is associated with allergic sensitisation: results from the LISA study
Allergy 64 (Suppl. 90), 50 - 50 10.1111/j.1398-9995.2009.02074.x - Herberth, G., Gubelt, R., Röder, S., Krämer, U., Schins, R., Diez, U., Borte, M., Heinrich, J., Wichmann, H.-E., Herbarth, O., Lehmann, I. (2009):
Increase of inflammatory markers after indoor renovation activities: The LISA birth cohort study.
Pediatr. Allergy Immunol. 20 (6), 563 - 570 10.1111/j.1399-3038.2008.00819.x - Herberth, G., Hinz, D., Röder, S., Diez, U., Borte, M., Lehmann, I. (2009):
Innate versus adaptive immune response in pregnant women and corresponding cord bloods
Cytom. Part A 75A (8), 717 - 718 10.1002/cyto.a.20752
2008 (4)
- Dägelmann, C., Herberth, G., Röder, S., Herbarth, O., Giese, T., Krämer, U., Behrendt, H., Borte, M., Heinrich, J., Emmrich, F., Lehmann, I. (2008):
Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children
Clin. Exp. Allergy 38 (3), 438 - 448 10.1111/j.1365-2222.2007.02913.x - Herberth, G., Gubelt, R., Röder, S., Krämer, U., Schins, R., Diez, U., Borte, M., Heinrich, J., Wichmann, H., Herbarth, O., Lehmann, I. (2008):
Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study
Allergy 63 (Suppl. 88), 471 10.1111/j.1398-9995.2008.01760.x - Herberth, G., Weber, A., Röder, S., Elvers, H.-D., Krämer, U., Schins, R.P.F., Diez, U., Borte, M., Heinrich, J., Schäfer, T., Herbarth, O., Lehmann, I. (2008):
Relation between stressful life events, neuropeptides and cytokines: results from the LISA birth cohort study
Pediatr. Allergy Immunol. 19 (8), 722 - 729 10.1111/j.1399-3038.2008.00727.x - Lehmann, I., Gubelt, R., Röder, S., Krämer, U., Schins, R., Borte, M., Diez, U., Heinrich, J., Behrendt, H., Herbarth, O., Herberth, G. (2008):
Sex-dependent differences in the impact of environmental tobacco smoke to inflammatory response and allergic sensitisation in children - results from the LISAplus study
Allergy 63 (Suppl. 88), 315 10.1111/j.1398-9995.2008.01760.x
2007 (4)
- Dägelmann, C., Herberth, G., Röder, S., Herbarth, O., Giese, T., Krämer, U., Behrendt, H., Borte, M., Lehmann, I. (2007):
Association between SOCS1 and SOCS3 expression, T-cell regulation and development of allergic manifestations in children
Allergy 62 (Suppl. 83), 461 - 462 10.1111/j.1398-9995.2007.01407.x - Herberth, G., Diez, U., Borte, M., Rehwagen, M., Röder, S., Herbarth, O., Lehmann, I. (2007):
Priming of the fetal immune system by chemical exposure increases the risk for allergy development later in children's life
Am. J. Reprod. Immunol. 58 (3), 196 - 197 10.1111/j.1600-0897.2007.00509.x - Herberth, G., Weber, A., Lehmann, I., Röder, S., Herbarth, O., Krämer, U., Borte, M., Diez, U., Heinrich, J. (2007):
Letter to the Editor. The stress of relocation and neuropeptides: an epidemiological study in children
J. Psychosomat. Res. 63 (4), 451 - 452 10.1016/j.jpsychores.2007.06.012 - Herberth, G., Weber, A., Röder, S., Elvers, H., Krämer, U., Schins, R., Diez, U., Borte, M., Zutavern, A., Schäfer, T., Herbarth, O., Lehmann, I. (2007):
Relation between stressful life events, expression of neuropeptides and immune regulation in children
Allergy 62 (Suppl. 83), 404 10.1111/j.1398-9995.2007.01407.x
2006 (3)
- Herberth, G., Dägelmann, C., Weber, A., Röder, S., Giese, T., Krämer, U., Schins, R.P.F., Behrendt, H., Borte, M., Lehmann, I. (2006):
Association of neuropeptides with Th1/Th2 balance and allergic sensitization in children
Clin. Exp. Allergy 36 (11), 1408 - 1416 10.1111/j.1365-2222.2006.02576.x - Herberth, G., Dägelmann, C., Weber, A., Röder, S., Giese, T., Krämer, U., Schins, R.P.F., Behrendt, H., Borte, M., Lehmann, I. (2006):
Association between neuropeptides, Th1/Th2 polarization and allergy risk in children
Cell Prolif. 39 (5), 365 10.1111/j.1365-2184.2006.00393.x - Trefzer, U., Chen, Y., Herberth, G., Hofmann, M.A., Kiecker, F., Guo, Y., Sterry, W. (2006):
The monoclonal antibody SM5-1 recognizes a fibronectin variant which is widely expressed in melanoma
BMC Cancer 6 , art. 8 10.1186/1471-2407-6-8
2005 (3)
- Herberth, G., Stein, A., Glienke, J., Taudien, S., Klaman, I., Herr, A., Thierauch, K.-H., Sommer, A. (2005):
Human latrophilin-2 is expressed in the cytotrophoblast and syncytiotrophoblast of placenta and in endothelial cells
American Journal of Biochemistry and Biotechnology 1 (3), 136 - 145 10.3844/ajbbsp.2005.135.144 - Reinke, S., Königer, P., Herberth, G., Audring, H., Wang, H., Ma, J., Guo, Y., Sterry, W., Trefzer, U. (2005):
Differential expression of MART-1, tyrosinase, and SM5-1 in primary and metastatic melanoma
Am. J. Dermatopathol. 27 (5), 401 - 406 10.1097/01.dad.0000180076.17932.ee - Trefzer, U., Herberth, G., Wohlan, K., Milling, A., Thiemann, M., Sharav, T., Sparbier, K., Sterry, W., Walden, P. (2005):
Tumour-dentritic hybrid cell vaccination for the treatment of patients with malignant melanoma: immunological effects and clinical results
Vaccine 23 (17-18), 2367 - 2373 10.1016/j.vaccine.2005.01.081
2004 (1)
- Trefzer, U., Herberth, G., Wohlan, K., Milling, A., Thiemann, M., Sherev, T., Sparbier, K., Sterry, W., Walden, P. (2004):
Vaccination with hybrids of tumor and dendritic cells induces tumor-specific T-cell and clinical responses in melanoma stage III and IV patients
Int. J. Cancer 110 (5), 730 - 740 10.1002/ijc.20191
2003 (1)
- Riemekasten, G., Langnickel, D., Ebling, F.M., Karpouzas, G., Kalsi, J., Herberth, G., Tsao, B.P., Henklein, P., Langer, S., Burmester, G.R., Radbruch, A., Hiepe, F., Hahn, B.H. (2003):
Identification and characterization of SmD183-119-reactive T cells that provide T cell help for pathogenic anti-double-stranded DNA antibodies
Arthritis Rheum. 48 (2), 475 - 485 10.1002/art.10762
2001 (1)
- Tumenjargal, S., Linnemann, T., Gellrich, S., Muche, M., Demine, R., Audring, H., Sparbier, K., Lukowsky, A., Herberth, G., Trefzer, U., Sterry, W., Walden, P. (2001):
T cell responses in cancer patients induced by tumour epitope-specific immune therapy
Cancer Gene Ther. 8 (11), 910
2000 (5)
- Herberth, G., Sterry, W., Walden, P., Trefzer, U. (2000):
Hybrid cell vaccination of patients with metastatic melanoma leads to the expansion of highly active antigen specific cytotoxic T lymphocytes
J. Invest. Dermatol. 115 (3), 588 10.1046/j.1523-1747.2000.115003527.x - Trefzer, U., Herberth, G., Sterry, W. (2000):
Presence of antigen-specific cytotoxic T lymphocytes (CTL) in metastasis of untreated melanoma patients
J. Invest. Dermatol. 115 (3), 563 10.1046/j.1523-1747.2000.115003527.x - Trefzer, U., Herberth, G., Sterry, W., Walden, P. (2000):
The hybrid cell vaccination approach to cancer immunotherapy
In: Walden, P., Sterry, W., Hennekes, H. (eds.)
Therapeutic vaccination strategies
Ernst Schering Research Foundation Workshop 30
Springer, Berlin, Heidelberg, p. 155 - 166 10.1007/978-3-662-04183-3_10 - Trefzer, U., Rietz, N., Chen, Y.W., Audring, H., Herberth, G., Siegel, P., Reinke, S., Königer, P., Wu, S.G., Ma, J., Liu, Y.J., Wang, H., Sterry, W., Cuo, Y.J. (2000):
SM5-1: a new monoclonal antibody which is highly sensitive and specific for melanocytic lesions
Arch. Dermatol. Res. 292 (12), 583 - 589 10.1007/s004030000186 - Trefzer, U., Weingart, G., Chen, Y.W., Herberth, G., Adrian, K., Winter, H., Audring, H., Guo, Y.J., Sterry, W., Walden, P. (2000):
Hybrid cell vaccination for cancer immune therapy: First clinical trial with metastatic melanoma
Int. J. Cancer 85 (5), 618 - 626 10.1002/(SICI)1097-0215(20000301)85:5<618::AID-IJC4>3.0.CO;2-Z