Dr. Kristin Junge
Contact
Dr. troph. Kristin Junge
Scientist, Theme Coordinator of
Nutritional immunology and metabolism
Helmholtz-Centre for
Environmental Research – UFZ
Department Environmental Immunology
Permoserstr. 15
04318 Leipzig, Germany
Phone: +49 341 235-1550
Email
Research Interests
- Perinatal exposure to lifestyle and environmental factors and overweight/allergy development in infancy: Impact of nutritional compounds (e.g. vitamin D) and epigenetics
- Research questions are addressed in a translational setting combining data from human epidemiological cohort studies with mechanistic investigations via disease associated stem cell culture models (adipocyte differentiation from mesenchymal stem cells, eosinophil/basophil progenitor cell differentiation/hematopoietic stem cells (Stem cells in Allergy and Obesity)
- Influence of nutritional compounds on atherogenesis and lipid metabolism
Curriculum vitae / Scientific career
since 12/2022
Professor for Nutritional Science at AKAD University Stuttgart, School of Health & Social Sciences
since 12/2022
Cooperating scientist at Helmholtz Centre for Environmental Research – UFZ Leipzig, Department of Environmental Immunology
12/2022
Opening of postdoctoral lecture qualification (Habilitationsverfahren) at Martin Luther University Halle-Wittenberg
since 10/2018
Teaching activity: Bachelor/Master student lectures “Nutritional Sciences”, Martin Luther University, Institute for Agricultural and Nutritional Sciences, Halle/Saale
01/2010 – 06/2010
Postdoc at McMaster University, Hamilton, ON, Canada
Department of Medicine, Division of Clinical Immunology and Allergy
since 06/2009
Scientist at the Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology
06/2006 - 06/2009
PhD-student/Scientist, Martin Luther University Halle-Wittenberg, Department of Human Nutrition
PhD thesis:
“Influence of lupin protein (L. angustifolius) on lipid metabolism and atherogenesis”
10/2001 - 06/2006
Student of Nutritional Sciences, Martin Luther University Halle-Wittenberg, Faculty of Natural Sciences III, Institute for Agricultural and Nutritional Sciences
Diploma thesis:
“Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAs in rats”
Awards / Grants
07/2014
Participation in 64th Nobel Laureate Meeting (Physiology/Medicine) after nomination by Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V. and qualification as highly-talented young researcher by the scientific review panel of the Council for the Lindau Nobel Laureate Meetings
01/2010
Luther-Award of Martin Luther University Halle-Wittenberg
12/2009
Postdoctoral fellowship/ research grant of the German academic exchange service (DAAD)
07/2007
Award of the society for the support of agricultural and nutritional sciences at the Martin Luther University Halle-Wittenberg e.V.
Publications
Index:
2022 (3)2021 (3)
2020 (1)
2018 (2)
2017 (1)
2016 (3)
2014 (2)
2013 (5)
2012 (6)
2011 (1)
2010 (4)
2008 (2)
2007 (1)
You could use our publication index for further requests.
2022 (3)
- Buchenauer, L., Junge, K.M., Haange, S.-B., Simon, J.C., von Bergen, M., Hoh, A.-L., Aust, G., Zenclussen, A.C., Stangl, G.I., Polte, T. (2022):
Glyphosate differentially affects the allergic immune response across generations in mice
Sci. Total Environ. 850 , art. 157973
full text (doi) - Junge, K.M., Buchenauer, L., Strunz, S., Seiwert, B., Thürmann, L., Rolle-Kampczyk, U.E., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Zenclussen, A.C., Schöneberg, T., Stangl, G.I., Herberth, G., Lehmann, I., Reemtsma, T., Polte, T. (2022):
Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study
Sci. Total Environ. 814 , art. 152676
full text (doi) - Schütte, O., Bachmann, L., Shivappa, N., Hebert, J.R., Felix, J.F., Röder, S.W., Sack, U., Borte, M., Kiess, W., Zenclussen, A.C., Stangl, G.I., Herberth, G., Junge, K.M. (2022):
Pro-inflammatory diet pictured in children with atopic dermatitis or food allergy: nutritional data of the LiNA cohort
Front. Nutr. 9 , art. 868872
full text (doi)
2021 (3)
- Junge, K.M., Buchenauer, L., Elter, E., Butter, K., Kohajda, T., Herberth, G., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Rolle-Kampczyk, U.E., Lehmann, I., Gminski, R., Ohlmeyer, M., Polte, T. (2021):
Wood emissions and asthma development: Results from an experimental mouse model and a prospective cohort study
Environ. Int. 151 , art. 106449
full text (doi) - Schaffert, A., Krieg, L., Weiner, J., Schlichting, R., Ueberham, E., Karkossa, I., Bauer, M., Landgraf, K., Junge, K.M., Wabitsch, M., Lehmann, J., Escher, B.I., Zenclussen, A.C., Körner, A., Blüher, M., Heiker, J.T., von Bergen, M., Schubert, K. (2021):
Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation
Environ. Int. 156 , art. 106730
full text (doi) - Schaffert, A., Krieg, L., Weinert, J., Schlichting, R., Ueberham, E., Karkossa, I., Bauer, M., Junge, K., Wabitsch, M., Lehmann, J., Escher, B.I., Zenclussen, A.C., Körner, A., Blüher, M., Heiker, J.T., von Bergen, M., Schubert, K. (2021):
Emerging substitutes of BPA cause inflammation-like state and impaired insulin sensitivity in differentiating human adipocytes
Toxicol. Lett. 350 (Suppl.), S130
full text (doi)
2020 (1)
- Leppert, B., Strunz, S., Seiwert, B., Schlittenbauer, L., Schlichting, R., Pfeifer, C., Röder, S., Bauer, M., Borte, M., Stangl, G.I., Schöneberg, T., Schulz, A., Karkossa, I., Rolle-Kampczyk, U.E., Thürmann, L., von Bergen, M., Escher, B.I., Junge, K.M., Reemtsma, T., Lehmann, I., Polte, T. (2020):
Maternal paraben exposure triggers childhood overweight development
Nat. Commun. 11 , art. 561
full text (doi)
2018 (2)
- Junge, K.M., Leppert, B., Jahreis, S., Wissenbach, D.K., Feltens, R., Grützmann, K., Thürmann, L., Bauer, T., Ishaque, N., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Schulz, A., Borte, M., Landgraf, K., Körner, A., Kiess, W., von Bergen, M., Stangl, G.I., Trump, S., Eils, R., Polte, T., Lehmann, I. (2018):
MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development
Clin. Epigenetics 10 , art. 58
full text (doi) - Leppert, B., Junge, K.M., Röder, S., Borte, M., Stangl, G.I., Wright, R.J., Hilbert, A., Lehmann, I., Trump, S. (2018):
Early maternal perceived stress and children’s BMI: longitudinal impact and influencing factors
BMC Public Health 18 , art. 1211
full text (doi)
2017 (1)
- Englich, B., Herberth, G., Rolle-Kampczyk, U., Trump, S., Röder, S., Borte, M., Stangl, G.I., von Bergen, M., Lehmann, I., Junge, K.M. (2017):
Maternal cytokine status may prime the metabolic profile and increase risk of obesity in children
Int. J. Obes. 41 (9), 1440 - 1446
full text (doi)
2016 (3)
- Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J.-P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K.M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R., Lehmann, I. (2016):
Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
Mol. Syst. Biol. 12 (3), art. 861
full text (doi) - Hörnig, F., Kohajda, T., Röder, S., Herberth, G., von Bergen, M., Borte, M., Diez, U., Rolle-Kampczyk, U., Simon, J.-C., Denburg, J.A., Lehmann, I., Junge, K.M. (2016):
The LINA study: higher sensitivity of infant compared to maternal eosinophil/basophil progenitors to indoor chemical exposures
J. Environ. Public Health 2016 , art. 5293932
full text (doi) - Junge, K.M., Bauer, T., Geissler, S., Hirche, F., Thürmann, L., Bauer, M., Trump, S., Bieg, M., Weichenhan, D., Gu, L., Mallm, J.-P., Ishaque, N., Mücke, O., Röder, S., Herberth, G., Diez, U., Borte, M., Rippe, K., Plass, C., Hermann, C., Stangl, G.I., Eils, R., Lehmann, I. (2016):
Increased vitamin D levels at birth and in early infancy increase offspring allergy risk—evidence for involvement of epigenetic mechanisms. Letter to the editor
J. Allergy Clin. Immunol. 137 (2), 610 - 613
full text (doi)
2014 (2)
- Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I. (2014):
Prenatal VOC exposure and redecoration are related to wheezing in early infancy
Environ. Int. 73 , 393 - 401
full text (doi) - Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I. (2014):
The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
Clin. Immunol. 152 (1-2), 68 - 76
full text (doi)
2013 (5)
- Jäger, N., Schlesner, M., Jones, D.T.W., Raffel, S., Mallm, J.-P., Junge, K.M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., Northcott, P.A., Korshunov, A., Drews, R.M., Koster, J., Versteeg, R., Richter, J., Hummel, M., Mack, S.C., Taylor, M.D., Witt, H., Swartman, B., Schulte-Bockholt, D., Sultan, M., Yaspo, M.-L., Lehrach, H., Hutter, B., Brors, B., Wolf, S., Plass, C., Siebert, R., Trumpp, A., Rippe, K., Lehmann, I., Lichter, P., Pfister, S.M., Eils, R. (2013):
Hypermutation of the inactive X chromosome is a frequent event in cancer
Cell 155 (3), 567 - 581
full text (doi) - Junge, K.M., Lehmann, I., Borte, M. (2013):
Can vitamin D intake during pregnancy affect the risk of allergy in children?
Expert Rev. Clin. Immunol. 9 (8), 699 - 701
full text (doi) - Querfeld, U., Keil, T., Beyer, K., Stock, P., Pilz, S., März, W., Weisse, K., Lehmann, I. (2013):
Vitamin D in early life: good or bad for food allergies?
Allergy 68 (8), 1081 - 1083
full text (doi) - Weisse, K., Herberth, G., Röder, S., Borte, M., Heroux, D., Denburg, J., Lehmann, I. (2013):
Eosinophil/basophil (Eo/B) progenitors in cord blood (CB) predict respiratory outcomes in early infancy
Allergy 68 (Suppl. 97), 53 - 53
full text (doi) - Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I. (2013):
Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
Allergy 68 (2), 220 - 228
full text (doi)
2012 (6)
- Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I. (2012):
Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
Allergy 67 (Suppl. 96), 574 - 574
full text (doi) - Lehmann, I., Weiße, K. (2012):
Rauchen beeinflusst allergierelevante Stammzellen
Pneumologie 66 (12), 702 - Weisse, K., Herberth, G., Roeder, S., Borte, M., Heroux, D., Denburg, J.A., Lehmann, I. (2012):
Cord blood (CB) eosinophil/basophil (Eo/B) progenitors predict respiratory outcomes until the age of two
J. Allergy Clin. Immunol. 129 (2, Suppl.), AB118 - AB118
full text (doi) - Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J. (2012):
The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
Clin. Exp. Allergy 42 (9), 1337 - 1346
full text (doi) - Weisse, K., Winkler, S., Stangl, G., Hirche, F., Herberth, G., Hinz, D., Röder, S., Borte, M., Richter, T., Lehmann, I. (2012):
Maternal and newborn vitamin D status and its impact on atopy development in the German LINA cohort study
Allergy 67 (Suppl. 96), 201 - 201
full text (doi) - Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I. (2012):
Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
J. Reprod. Immunol. 94 (1), 53 - 54
full text (doi)
2011 (1)
- Weisse, K., Lehmann, I., Herberth, G., Kohajda, T., Röder, S., Borte, M., Heroux, A., Denburg, J. (2011):
Circulating eosinophil/basophil (Eo/B) progenitors at one year of age positively correlate with atopic eczema and indoor chemical exposure in the LINA Study
J. Allergy Clin. Immunol. 127 (2), AB146 - AB146
full text (doi)
2010 (4)
- Brandsch, C., Kappis, D., Weisse, K., Stangl, G.I. (2010):
Effects of untreated and thermally treated lupin protein on plasma and liver lipids of rats fed a hypercholesterolemic high fat or high carbohydrate diet
Plant Food Hum. Nutr. 65 (4), 410 - 416
full text (doi) - Brandsch, C., Schmidt, T., Behn, D., Weisse, K., Mueller, A.S., Stangl, G.I. (2010):
Glutathione deficiency down-regulates hepatic lipogenesis in rats
Lipids Health Dis. 9 , art. 50
full text (doi) - Weisse, K., Brandsch, C., Hirche, F., Eder, K., Stangl, G.I. (2010):
Lupin protein isolate and cysteine-supplemented casein reduce calcification of atherosclerotic lesions in apoE-deficient mice
Br. J. Nutr. 103 (2), 180 - 188
full text (doi) - Weisse, K., Brandsch, C., Zernsdorf, B., Nkengfack Nembongwe, G.S., Hofmann, K., Eder, K., Stangl, G. (2010):
Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults
Eur. J. Nutr. 49 (2), 65 - 71
full text (doi)
2008 (2)
- Bettzieche, A., Brandsch, C., Schmidt, M., Weisse, K., Eder, K., Stangl, G.I. (2008):
Differing effect of protein isolates from different cultivars of blue lupin on plasma lipoproteins of hypercholesterolemic rats
Biosci. Biotechnol. Biochem. 72 (12), 3114 - 3121
full text (doi) - Bettzieche, A., Brandsch, C., Weisse, K., Hirche, F., Eder, K., Stangl, G.I. (2008):
Lupin protein influences the expression of hepatic genes involved in fatty acid synthesis and triacylglycerol hydrolysis of adult rats
Br. J. Nutr. 99 (5), 952 - 962
full text (doi)
2007 (1)
- Stangl, G.I., Weisse, K., Dinger, C., Hirche, F., Brandsch, C., Eder, K. (2007):
Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAs in rats
Exp. Biol. Med. 232 (1), 81 - 87