Dr. Kristin Junge
Kontakt
Dr. troph. Kristin Junge
Wissenschaftlerin, Themenkoordinatorin für
Ernährungsassoziierte Veränderungen in Immunsystem und Stoffwechsel
Helmholtz-Zentrum für
Umweltforschung – UFZ
Department Umweltimmunologie
Permoserstr. 15
04318 Leipzig
E-Mail
Forschungsinteressen
- Perinatal exposure to lifestyle and environmental factors and overweight/allergy development in infancy: Impact of nutritional compounds (e.g. vitamin D) and epigenetics
- Research questions are addressed in a translational setting combining data from human epidemiological cohort studies with mechanistic investigations via disease associated stem cell culture models (adipocyte differentiation from mesenchymal stem cells, eosinophil/basophil progenitor cell differentiation/hematopoietic stem cells (Stem cells in Allergy and Obesity)
- Influence of nutritional compounds on atherogenesis and lipid metabolism
Lebenslauf
since 12/2022
Professor for Nutritional Science at AKAD University Stuttgart, School of Health & Social Sciences
since 12/2022
Cooperating scientist at Helmholtz Centre for Environmental Research – UFZ Leipzig, Department of Environmental Immunology
12/2022
Opening of postdoctoral lecture qualification (Habilitationsverfahren) at Martin Luther University Halle-Wittenberg
since 10/2018
Teaching activity: Bachelor/Master student lectures “Nutritional Sciences”, Martin Luther University, Institute for Agricultural and Nutritional Sciences, Halle/Saale
01/2010 – 06/2010
Postdoc at McMaster University, Hamilton, ON, Canada
Department of Medicine, Division of Clinical Immunology and Allergy
since 06/2009
Scientist at the Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology
06/2006 - 06/2009
PhD-student/Scientist, Martin Luther University Halle-Wittenberg, Department of Human Nutrition
PhD thesis:
“Influence of lupin protein (L. angustifolius) on lipid metabolism and atherogenesis”
10/2001 - 06/2006
Student of Nutritional Sciences, Martin Luther University Halle-Wittenberg, Faculty of Natural Sciences III, Institute for Agricultural and Nutritional Sciences
Diploma thesis:
“Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAs in rats”
Auszeichnungen
07/2014
Participation in 64th Nobel Laureate Meeting (Physiology/Medicine) after nomination by Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V. and qualification as highly-talented young researcher by the scientific review panel of the Council for the Lindau Nobel Laureate Meetings
01/2010
Luther-Award of Martin Luther University Halle-Wittenberg
12/2009
Postdoctoral fellowship/ research grant of the German academic exchange service (DAAD)
07/2007
Award of the society for the support of agricultural and nutritional sciences at the Martin Luther University Halle-Wittenberg e.V.
Publikationen
Inhalt:
- 2023 (2)
- 2022 (3)
- 2021 (3)
- 2020 (1)
- 2018 (2)
- 2017 (1)
- 2016 (3)
- 2014 (2)
- 2013 (5)
- 2012 (6)
- 2011 (1)
- 2010 (4)
- 2008 (2)
- 2007 (1)
Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.
2023 (2)
- Buchenauer, L., Haange, S.-B., Bauer, M., Rolle-Kampczyk, U.E., Wagner, M., Stucke, J., Elter, E., Fink, B., Vass, M., von Bergen, M., Schulz, A., Zenclussen, A.C., Junge, K.M., Stangl, G.I., Polte, T. (2023):
Maternal exposure of mice to glyphosate induces depression- and anxiety-like behavior in the offspring via alterations of the gut-brain axis
Sci. Total Environ. 905 , art. 167034
Volltext (DOI) - Junge, K.M., Zenclussen, A.C., Desoye, G. (2023):
(Über‑)Ernährung und Einfluss auf die Funktion der Plazenta
Diabetologie 19 (6), 747 - 757
Volltext (DOI)
2022 (3)
- Buchenauer, L., Junge, K.M., Haange, S.-B., Simon, J.C., von Bergen, M., Hoh, A.-L., Aust, G., Zenclussen, A.C., Stangl, G.I., Polte, T. (2022):
Glyphosate differentially affects the allergic immune response across generations in mice
Sci. Total Environ. 850 , art. 157973
Volltext (DOI) - Junge, K.M., Buchenauer, L., Strunz, S., Seiwert, B., Thürmann, L., Rolle-Kampczyk, U.E., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Zenclussen, A.C., Schöneberg, T., Stangl, G.I., Herberth, G., Lehmann, I., Reemtsma, T., Polte, T. (2022):
Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study
Sci. Total Environ. 814 , art. 152676
Volltext (DOI) - Schütte, O., Bachmann, L., Shivappa, N., Hebert, J.R., Felix, J.F., Röder, S.W., Sack, U., Borte, M., Kiess, W., Zenclussen, A.C., Stangl, G.I., Herberth, G., Junge, K.M. (2022):
Pro-inflammatory diet pictured in children with atopic dermatitis or food allergy: nutritional data of the LiNA cohort
Front. Nutr. 9 , art. 868872
Volltext (DOI)
2021 (3)
- Junge, K.M., Buchenauer, L., Elter, E., Butter, K., Kohajda, T., Herberth, G., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Rolle-Kampczyk, U.E., Lehmann, I., Gminski, R., Ohlmeyer, M., Polte, T. (2021):
Wood emissions and asthma development: Results from an experimental mouse model and a prospective cohort study
Environ. Int. 151 , art. 106449
Volltext (DOI) - Schaffert, A., Krieg, L., Weiner, J., Schlichting, R., Ueberham, E., Karkossa, I., Bauer, M., Landgraf, K., Junge, K.M., Wabitsch, M., Lehmann, J., Escher, B.I., Zenclussen, A.C., Körner, A., Blüher, M., Heiker, J.T., von Bergen, M., Schubert, K. (2021):
Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation
Environ. Int. 156 , art. 106730
Volltext (DOI) - Schaffert, A., Krieg, L., Weinert, J., Schlichting, R., Ueberham, E., Karkossa, I., Bauer, M., Junge, K., Wabitsch, M., Lehmann, J., Escher, B.I., Zenclussen, A.C., Körner, A., Blüher, M., Heiker, J.T., von Bergen, M., Schubert, K. (2021):
Emerging substitutes of BPA cause inflammation-like state and impaired insulin sensitivity in differentiating human adipocytes
Toxicol. Lett. 350 (Suppl.), S130
Volltext (DOI)
2020 (1)
- Leppert, B., Strunz, S., Seiwert, B., Schlittenbauer, L., Schlichting, R., Pfeifer, C., Röder, S., Bauer, M., Borte, M., Stangl, G.I., Schöneberg, T., Schulz, A., Karkossa, I., Rolle-Kampczyk, U.E., Thürmann, L., von Bergen, M., Escher, B.I., Junge, K.M., Reemtsma, T., Lehmann, I., Polte, T. (2020):
Maternal paraben exposure triggers childhood overweight development
Nat. Commun. 11 , art. 561
Volltext (DOI)
2018 (2)
- Junge, K.M., Leppert, B., Jahreis, S., Wissenbach, D.K., Feltens, R., Grützmann, K., Thürmann, L., Bauer, T., Ishaque, N., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Schulz, A., Borte, M., Landgraf, K., Körner, A., Kiess, W., von Bergen, M., Stangl, G.I., Trump, S., Eils, R., Polte, T., Lehmann, I. (2018):
MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development
Clin. Epigenetics 10 , art. 58
Volltext (DOI) - Leppert, B., Junge, K.M., Röder, S., Borte, M., Stangl, G.I., Wright, R.J., Hilbert, A., Lehmann, I., Trump, S. (2018):
Early maternal perceived stress and children’s BMI: longitudinal impact and influencing factors
BMC Public Health 18 , art. 1211
Volltext (DOI)
2017 (1)
- Englich, B., Herberth, G., Rolle-Kampczyk, U., Trump, S., Röder, S., Borte, M., Stangl, G.I., von Bergen, M., Lehmann, I., Junge, K.M. (2017):
Maternal cytokine status may prime the metabolic profile and increase risk of obesity in children
Int. J. Obes. 41 (9), 1440 - 1446
Volltext (DOI)
2016 (3)
- Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J.-P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K.M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R., Lehmann, I. (2016):
Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
Mol. Syst. Biol. 12 (3), art. 861
Volltext (DOI) - Hörnig, F., Kohajda, T., Röder, S., Herberth, G., von Bergen, M., Borte, M., Diez, U., Rolle-Kampczyk, U., Simon, J.-C., Denburg, J.A., Lehmann, I., Junge, K.M. (2016):
The LINA study: higher sensitivity of infant compared to maternal eosinophil/basophil progenitors to indoor chemical exposures
J. Environ. Public Health 2016 , art. 5293932
Volltext (DOI) - Junge, K.M., Bauer, T., Geissler, S., Hirche, F., Thürmann, L., Bauer, M., Trump, S., Bieg, M., Weichenhan, D., Gu, L., Mallm, J.-P., Ishaque, N., Mücke, O., Röder, S., Herberth, G., Diez, U., Borte, M., Rippe, K., Plass, C., Hermann, C., Stangl, G.I., Eils, R., Lehmann, I. (2016):
Increased vitamin D levels at birth and in early infancy increase offspring allergy risk—evidence for involvement of epigenetic mechanisms. Letter to the editor
J. Allergy Clin. Immunol. 137 (2), 610 - 613
Volltext (DOI)
2014 (2)
- Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I. (2014):
Prenatal VOC exposure and redecoration are related to wheezing in early infancy
Environ. Int. 73 , 393 - 401
Volltext (DOI) - Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I. (2014):
The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
Clin. Immunol. 152 (1-2), 68 - 76
Volltext (DOI)
2013 (5)
- Jäger, N., Schlesner, M., Jones, D.T.W., Raffel, S., Mallm, J.-P., Junge, K.M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., Northcott, P.A., Korshunov, A., Drews, R.M., Koster, J., Versteeg, R., Richter, J., Hummel, M., Mack, S.C., Taylor, M.D., Witt, H., Swartman, B., Schulte-Bockholt, D., Sultan, M., Yaspo, M.-L., Lehrach, H., Hutter, B., Brors, B., Wolf, S., Plass, C., Siebert, R., Trumpp, A., Rippe, K., Lehmann, I., Lichter, P., Pfister, S.M., Eils, R. (2013):
Hypermutation of the inactive X chromosome is a frequent event in cancer
Cell 155 (3), 567 - 581
Volltext (DOI) - Junge, K.M., Lehmann, I., Borte, M. (2013):
Can vitamin D intake during pregnancy affect the risk of allergy in children?
Expert Rev. Clin. Immunol. 9 (8), 699 - 701
Volltext (DOI) - Querfeld, U., Keil, T., Beyer, K., Stock, P., Pilz, S., März, W., Weisse, K., Lehmann, I. (2013):
Vitamin D in early life: good or bad for food allergies?
Allergy 68 (8), 1081 - 1083
Volltext (DOI) - Weisse, K., Herberth, G., Röder, S., Borte, M., Heroux, D., Denburg, J., Lehmann, I. (2013):
Eosinophil/basophil (Eo/B) progenitors in cord blood (CB) predict respiratory outcomes in early infancy
Allergy 68 (Suppl. 97), 53 - 53
Volltext (DOI) - Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I. (2013):
Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
Allergy 68 (2), 220 - 228
Volltext (DOI)
2012 (6)
- Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I. (2012):
Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
Allergy 67 (Suppl. 96), 574 - 574
Volltext (DOI) - Lehmann, I., Weiße, K. (2012):
Rauchen beeinflusst allergierelevante Stammzellen
Pneumologie 66 (12), 702 - Weisse, K., Herberth, G., Roeder, S., Borte, M., Heroux, D., Denburg, J.A., Lehmann, I. (2012):
Cord blood (CB) eosinophil/basophil (Eo/B) progenitors predict respiratory outcomes until the age of two
J. Allergy Clin. Immunol. 129 (2, Suppl.), AB118 - AB118
Volltext (DOI) - Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J. (2012):
The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
Clin. Exp. Allergy 42 (9), 1337 - 1346
Volltext (DOI) - Weisse, K., Winkler, S., Stangl, G., Hirche, F., Herberth, G., Hinz, D., Röder, S., Borte, M., Richter, T., Lehmann, I. (2012):
Maternal and newborn vitamin D status and its impact on atopy development in the German LINA cohort study
Allergy 67 (Suppl. 96), 201 - 201
Volltext (DOI) - Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I. (2012):
Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
J. Reprod. Immunol. 94 (1), 53 - 54
Volltext (DOI)
2011 (1)
- Weisse, K., Lehmann, I., Herberth, G., Kohajda, T., Röder, S., Borte, M., Heroux, A., Denburg, J. (2011):
Circulating eosinophil/basophil (Eo/B) progenitors at one year of age positively correlate with atopic eczema and indoor chemical exposure in the LINA Study
J. Allergy Clin. Immunol. 127 (2), AB146 - AB146
Volltext (DOI)
2010 (4)
- Brandsch, C., Kappis, D., Weisse, K., Stangl, G.I. (2010):
Effects of untreated and thermally treated lupin protein on plasma and liver lipids of rats fed a hypercholesterolemic high fat or high carbohydrate diet
Plant Food Hum. Nutr. 65 (4), 410 - 416
Volltext (DOI) - Brandsch, C., Schmidt, T., Behn, D., Weisse, K., Mueller, A.S., Stangl, G.I. (2010):
Glutathione deficiency down-regulates hepatic lipogenesis in rats
Lipids Health Dis. 9 , art. 50
Volltext (DOI) - Weisse, K., Brandsch, C., Hirche, F., Eder, K., Stangl, G.I. (2010):
Lupin protein isolate and cysteine-supplemented casein reduce calcification of atherosclerotic lesions in apoE-deficient mice
Br. J. Nutr. 103 (2), 180 - 188
Volltext (DOI) - Weisse, K., Brandsch, C., Zernsdorf, B., Nkengfack Nembongwe, G.S., Hofmann, K., Eder, K., Stangl, G. (2010):
Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults
Eur. J. Nutr. 49 (2), 65 - 71
Volltext (DOI)
2008 (2)
- Bettzieche, A., Brandsch, C., Schmidt, M., Weisse, K., Eder, K., Stangl, G.I. (2008):
Differing effect of protein isolates from different cultivars of blue lupin on plasma lipoproteins of hypercholesterolemic rats
Biosci. Biotechnol. Biochem. 72 (12), 3114 - 3121
Volltext (DOI) - Bettzieche, A., Brandsch, C., Weisse, K., Hirche, F., Eder, K., Stangl, G.I. (2008):
Lupin protein influences the expression of hepatic genes involved in fatty acid synthesis and triacylglycerol hydrolysis of adult rats
Br. J. Nutr. 99 (5), 952 - 962
Volltext (DOI)
2007 (1)
- Stangl, G.I., Weisse, K., Dinger, C., Hirche, F., Brandsch, C., Eder, K. (2007):
Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAs in rats
Exp. Biol. Med. 232 (1), 81 - 87