Dr. Kristin Junge

Kontakt

Dr. Kristin Junge

Wissenschaftler

Department Umweltimmunologie
Helmholtz-Zentrum für Umweltforschung – UFZ
Permoserstr. 15
04318 Leipzig


Tel.: +49 341 235-1547
Fax: +49 341 235-1787

Kristin M. Junge

Research Interests


• Influence of environmental exposures on phenotype and function of allergy relevant hematopoietic stem cells (Eo/B progenitor cells) Webseite Stammzellen in Allergie und Adipositas 

• Investigations of maternal, newborn and infant vitamin D status on epigenetics and allergy development in the German LINA cohort study

• Influence of environmental exposures on phenotype and function of adipocyte derived mesenchymal stem cells Webseite Stammzellen in Allergie und Adipositas

• Influence of nutritional compounds on epigenetics and overweight development in the German LINA cohort study

• Influence of nutritional compounds on lipid metabolism and atherogenesis


Curriculum vitae / Scientific career

10/2001 - 06/2006

Student of Nutritional Sciences, Martin-Luther-University Halle-Wittenberg, Faculty of Natural Sciences III, Institute for Agricultural and Nutritional Sciences

Diploma thesis:
“Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAs in rats”

06/2006 - 12/2008

PhD-student, Martin-Luther-University Halle-Wittenberg, Department of Human Nutrition (Prof. Dr. G.I. Stangl)

PhD thesis:
“Influence of lupin protein (L. angustifolius) on lipid metabolism and atherogenesis”

05/2009 - 06/2009

Scientist, Martin-Luther University Halle-Wittenberg, Department of Human Nutrition (Prof. Dr. G.I. Stangl)

06/2009 - 12/2009

Postdoc at the Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology (Dr. Irina Lehmann)

01/2010 – 06/2010

Postdoc at McMaster University, Hamilton, ON, Canada
Department of Medicine, Division of Clinical Immunology and Allergy (Prof. J.A. Denburg)

since 07/2010

Scientist at the Helmholtz Centre for Environmental Research – UFZ, Department of Environmental Immunology (Dr. Irina Lehmann)

06/2014 - 07/2014

Participation in 64th Nobel Laureate Meeting (Physiology/Medicine) after nomination by Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V. and qualification as highly-talented young researcher by the scientific review panel of the Council for the Lindau Nobel Laureate Meetings

Awards

07/2007

Award of the society for the support of agricultural and nutritional sciences at the Martin-Luther-University Halle-Wittenberg e.V.

12/2009

Postdoctoral fellowship/ research grant of the German academic exchange service (DAAD)

01/2010

Luther-Award of Martin-Luther-University Halle-Wittenberg


Publications

Inhalt:

2018 (2)
2017 (1)
2016 (3)
2014 (2)
2013 (5)
2012 (6)
2011 (1)
2010 (4)
2008 (2)
2007 (1)

Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.

2018 (2)

  • Junge, K.M., Leppert, B., Jahreis, S., Wissenbach, D.K., Feltens, R., Grützmann, K., Thürmann, L., Bauer, T., Ishaque, N., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Schulz, A., Borte, M., Landgraf, K., Körner, A., Kiess, W., von Bergen, M., Stangl, G.I., Trump, S., Eils, R., Polte, T., Lehmann, I., (2018):
    MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development
    Clin. Epigenetics 10 , art. 58
    Volltext (URL)
  • Leppert, B., Junge, K.M., Röder, S., Borte, M., Stangl, G.I., Wright, R.J., Hilbert, A., Lehmann, I., Trump, S., (2018):
    Early maternal perceived stress and children’s BMI: longitudinal impact and influencing factors
    BMC Public Health 18 , art. 1211
    Volltext (URL)
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2017 (1)

  • Englich, B., Herberth, G., Rolle-Kampczyk, U., Trump, S., Röder, S., Borte, M., Stangl, G.I., von Bergen, M., Lehmann, I., Junge, K.M., (2017):
    Maternal cytokine status may prime the metabolic profile and increase risk of obesity in children
    Int. J. Obes. 41 (9), 1440 - 1446
    Volltext (URL)
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2016 (3)

  • Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J.-P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K.M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R., Lehmann, I., (2016):
    Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
    Mol. Syst. Biol. 12 (3), art. 861
    Volltext (URL)
  • Hörnig, F., Kohajda, T., Röder, S., Herberth, G., von Bergen, M., Borte, M., Diez, U., Rolle-Kampczyk, U., Simon, J.-C., Denburg, J.A., Lehmann, I., Junge, K.M., (2016):
    The LINA study: higher sensitivity of infant compared to maternal eosinophil/basophil progenitors to indoor chemical exposures
    J. Environ. Public Health 2016 , art. 5293932
    Volltext (URL)
  • Junge, K.M., Bauer, T., Geissler, S., Hirche, F., Thürmann, L., Bauer, M., Trump, S., Bieg, M., Weichenhan, D., Gu, L., Mallm, J.-P., Ishaque, N., Mücke, O., Röder, S., Herberth, G., Diez, U., Borte, M., Rippe, K., Plass, C., Hermann, C., Stangl, G.I., Eils, R., Lehmann, I., (2016):
    Increased vitamin D levels at birth and in early infancy increase offspring allergy risk—evidence for involvement of epigenetic mechanisms. Letter to the editor
    J. Allergy Clin. Immunol. 137 (2), 610 - 613
    Volltext (URL)
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2014 (2)

  • Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I., (2014):
    Prenatal VOC exposure and redecoration are related to wheezing in early infancy
    Environ. Int. 73 , 393 - 401
    Volltext (URL)
  • Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I., (2014):
    The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
    Clin. Immunol. 152 (1-2), 68 - 76
    Volltext (URL)
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2013 (5)

  • Jäger, N., Schlesner, M., Jones, D.T.W., Raffel, S., Mallm, J.-P., Junge, K.M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., Northcott, P.A., Korshunov, A., Drews, R.M., Koster, J., Versteeg, R., Richter, J., Hummel, M., Mack, S.C., Taylor, M.D., Witt, H., Swartman, B., Schulte-Bockholt, D., Sultan, M., Yaspo, M.-L., Lehrach, H., Hutter, B., Brors, B., Wolf, S., Plass, C., Siebert, R., Trumpp, A., Rippe, K., Lehmann, I., Lichter, P., Pfister, S.M., Eils, R., (2013):
    Hypermutation of the inactive X chromosome is a frequent event in cancer
    Cell 155 (3), 567 - 581
    Volltext (URL)
  • Junge, K.M., Lehmann, I., Borte, M., (2013):
    Can vitamin D intake during pregnancy affect the risk of allergy in children?
    Expert Rev. Clin. Immunol. 9 (8), 699 - 701
    Volltext (URL)
  • Querfeld, U., Keil, T., Beyer, K., Stock, P., Pilz, S., März, W., Weisse, K., Lehmann, I., (2013):
    Vitamin D in early life: good or bad for food allergies?
    Allergy 68 (8), 1081 - 1083
    Volltext (URL)
  • Weisse, K., Herberth, G., Röder, S., Borte, M., Heroux, D., Denburg, J., Lehmann, I., (2013):
    Eosinophil/basophil (Eo/B) progenitors in cord blood (CB) predict respiratory outcomes in early infancy
    Allergy 68 (Suppl. 97), 53 - 53
    Volltext (URL)
  • Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I., (2013):
    Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
    Allergy 68 (2), 220 - 228
    Volltext (URL)
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2012 (6)

  • Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I., (2012):
    Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
    Allergy 67 (Suppl. 96), 574 - 574
    Volltext (URL)
  • Lehmann, I., Weiße, K., (2012):
    Rauchen beeinflusst allergierelevante Stammzellen
    Pneumologie 66 (12), 702
  • Weisse, K., Herberth, G., Roeder, S., Borte, M., Heroux, D., Denburg, J.A., Lehmann, I., (2012):
    Cord blood (CB) eosinophil/basophil (Eo/B) progenitors predict respiratory outcomes until the age of two
    J. Allergy Clin. Immunol. 129 (2, Suppl.), AB118 - AB118
    Volltext (URL)
  • Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J., (2012):
    The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
    Clin. Exp. Allergy 42 (9), 1337 - 1346
    Volltext (URL)
  • Weisse, K., Winkler, S., Stangl, G., Hirche, F., Herberth, G., Hinz, D., Röder, S., Borte, M., Richter, T., Lehmann, I., (2012):
    Maternal and newborn vitamin D status and its impact on atopy development in the German LINA cohort study
    Allergy 67 (Suppl. 96), 201 - 201
    Volltext (URL)
  • Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I., (2012):
    Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
    J. Reprod. Immunol. 94 (1), 53 - 54
    Volltext (URL)
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2011 (1)

  • Weisse, K., Lehmann, I., Herberth, G., Kohajda, T., Röder, S., Borte, M., Heroux, A., Denburg, J., (2011):
    Circulating eosinophil/basophil (Eo/B) progenitors at one year of age positively correlate with atopic eczema and indoor chemical exposure in the LINA Study
    J. Allergy Clin. Immunol. 127 (2), AB146 - AB146
    Volltext (URL)
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2010 (4)

  • Brandsch, C., Kappis, D., Weisse, K., Stangl, G.I., (2010):
    Effects of untreated and thermally treated lupin protein on plasma and liver lipids of rats fed a hypercholesterolemic high fat or high carbohydrate diet
    Plant Food Hum. Nutr. 65 (4), 410 - 416
    Volltext (URL)
  • Brandsch, C., Schmidt, T., Behn, D., Weisse, K., Mueller, A.S., Stangl, G.I., (2010):
    Glutathione deficiency down-regulates hepatic lipogenesis in rats
    Lipids Health Dis. 9 , art. 50
    Volltext (URL)
  • Weisse, K., Brandsch, C., Hirche, F., Eder, K., Stangl, G.I., (2010):
    Lupin protein isolate and cysteine-supplemented casein reduce calcification of atherosclerotic lesions in apoE-deficient mice
    Br. J. Nutr. 103 (2), 180 - 188
    Volltext (URL)
  • Weisse, K., Brandsch, C., Zernsdorf, B., Nkengfack Nembongwe, G.S., Hofmann, K., Eder, K., Stangl, G., (2010):
    Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults
    Eur. J. Nutr. 49 (2), 65 - 71
    Volltext (URL)
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2008 (2)

  • Bettzieche, A., Brandsch, C., Schmidt, M., Weisse, K., Eder, K., Stangl, G.I., (2008):
    Differing effect of protein isolates from different cultivars of blue lupin on plasma lipoproteins of hypercholesterolemic rats
    Biosci. Biotechnol. Biochem. 72 (12), 3114 - 3121
    Volltext (URL)
  • Bettzieche, A., Brandsch, C., Weisse, K., Hirche, F., Eder, K., Stangl, G.I., (2008):
    Lupin protein influences the expression of hepatic genes involved in fatty acid synthesis and triacylglycerol hydrolysis of adult rats
    Br. J. Nutr. 99 (5), 952 - 962
    Volltext (URL)
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2007 (1)

  • Stangl, G.I., Weisse, K., Dinger, C., Hirche, F., Brandsch, C., Eder, K., (2007):
    Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAs in rats
    Exp. Biol. Med. 232 (1), 81 - 87
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