Prof. Ana Zenclussen


Prof. Ana Zenclussen

Head of the Department Environmental Immunology and Theme Coordinator of
Perinatal exposure of chemicals having pregnancy/birth effects

Helmholtz-Centre for
Environmental Research – UFZ
Department of Environmental Immunology
Permoserstr. 15
04318 Leipzig, Germany

Phone: +49 341 6025-1265

Prof. Ana Zenclussen, Leiterin des Departments Umweltimmunologie
Photo: André Künzelmann/UFZ

Curriculum vitae / Scientific career

since July 2020

W3 Professorship at the Medical Faculty of the Leipzig University and Head of the Department of Environmental Immunology at the Helmholtz Centre for Environmental Research - UFZ in Leipzig

May 2007 - July 2020

W2 Professorship Otto von Guericke University Magdeburg, Medical Faculty (Experimental Gynecology and Obstetrics with focus on Immunology)


Habilitation and authorisation to teach. Charité, University Medicine Berlin

2003 - May 2007

Teamleader and scientist at the Institute of Medical Immunology (Prof. Dr. Hans-Dieter Volk), Charité, Humboldt University of Berlin.

2001 - 2003

Postdoc and Alexander von Humboldt Scholarship holder, Charité, Humboldt University of Berlin


DAAD scholarship at BMFZ, Charité, Humboldt University of Berlin

1996 - 2001

PhD, (Dr.rer.nat.) at the University of Buenos Aires, Department of Immunology, Head: Prof. Dr. Ricardo Margni. Graduation with „excellent“ (10).

1990 - 1996

Study of Biochemistry at the „Universidad Nacional del Litoral“, Santa Fe, Argentina


  • The American Association of Immunologists (AAI)
  • Deutsche Gesellschaft für Immunologie (DGfI)
  • Society for Reproduction and Fertility (SRF)
  • European Mast Cell and Basophil Research Network (EMBRN)
  • EU COST Action BM1007 "Mast cells and basophils"
  • European Society for Reproductive Immunology (ESRI)
  • Deutsche Allianz Klimwandel und Gesundheit (KLUG)


Own third-party funded projects

2024 - 2027

ENDOMIX: Understanding how endocrine disruptors and chemical mixtures of concern target the immune system to trigger or perpetuate disease

2023 - 2026

LE-REP: Interdisciplinary Leipzig Reproductive Health Research Center (BMBF)

2021 - 2025

Virological and immunological determinants of COVID-19 pathogenesis – lessons to get prepared for future pandemics

2020 - 2025

Influence of endocrine disruptors on reproductive processes mediated by immune cells of the innate immune system. Deutsche Forschungsgemeinschaft, ZE 526/16-1

2019 - 2020

The influence of the herbicide glyphosate on carcinogenesis in the inflammatory microenvironment of HPV infected epithelial cells of the female genital tract. Else Kröner-Fresenius-Stiftung (Else Kröner Forschungskolleg MD, 2. Förderperiode, TP2)

2018 - 2021

Cold shock proteins in reproduction: relevance of the expression of trophoblast-specific YB-1 for embryonic development. Deutsche Forschungsgemeinschaft, ZE 526/14-1


Interdisciplinary Autumn School for Reproductive Sciences and related Research Fields. Volkswagen Stiftung Az: 93 324

2017 - 2019

Influence of mast cells and their mediators on the growth and development of ovarial tumours. Wilhelm-Sander-Stiftung Förderkennzeichen 2016.146.1

2016 - 2018

Influence of environmental estrogens on endocrine factors that modulate the immune response during pregnancy. BMBF AZ ARGWTZ-56

2015 - 2018

Unraveling the molecular mechanisms of B-cell associated IL-10 protective effects in pre-term delivery. Else Kröner-Fresenius-Stiftung. Az. 2014_A121

2015 - 2022

Investigation of the protective HO-1-associated mechanisms during implantation, placentation and fetal growth in the mouse model and on the basis of in vitro models. Involvement of carbon monoxide in the preparation of an optimal uterine micromillieus for murine pregnancy. Deutsche Forschungsgemeinschaft, ZE 526/12-1

2015 - 2016

Uterine inflammatory microenvironment after chlamydia infection as a risk for cervical carcinoma: role of hemoxygenase-1 and therapeutic perspectives in a mouse model. Else Kröner-Fresenius-Stiftung (Else Kröner Forschungskolleg MD, TP3)


Round table dicussion: "Female reproductive Biology and Immunology" from German-speaking countries with the aim of initiating or intensifying scientific cooperations. Deutsche Forschungsgemeinschaft, ZE 526/10-1

2012 - 2015

Mast cells as critical regulators of tissue remodelling during implantation and placentation mechanisms of activation and mediators. Deutsche Forschungsgemeinschaft, ZE 526/6-2 (SPP 1394)


Interdisciplinary Autumn School for Reproductive Sciences and immunology. Deutsche Forschungsgemeinschaft, ZE 526/8-1

2010 - 2012

Human chorionic gonadotropin and luteinizing hormone as chemoattractors of regulatory T cells in pregnancy. Deutsche Forschungsgemeinschaft, ZE 526/7-1

2009 - 2012

Expressions regulation of Y-P30 in maternal T cells and its influence on the neuritogenesis of thalamic/cortical neurons. Deutsche Forschungsgemeinschaft,SFB 854 TP7

2009 - 2012

Mast cells as novel regulators of tolerance at the fetal-meternal interface: their role in pregnancy success as „Treg-helpers“ an study of their therapeutic potential in spontaneous abortions. Deutsche Forschungsgemeinschaft, ZE 526/6-1 (SPP 1394)

2008 - 2009

Characterization of new tolerance mechanisms in two different in vivo models. DAAD D/07/09571

2008 - 2009

Participation of mast cells in regulatory T cells (Treg)-induced tolerance at the fetal-maternal interface: Consequences of mast cells or mast cell-related genes absence in pregnancy outcome. Fritz-Thyssen Stiftung Az.

2008 - 2009

Continuation proposal: Reprogramming of tolerance in murine models of immunological pregnancy complications using regulatory T cells II. Deutsche Forschungsgemeinschaft, ZE 526/4-2 

2007 - 2009

Study of the therapeutic potential of CO during implantation in a mouse model of spontaneous abortion. GEMI Fund, Karolinska/Harvard, 018/07

2006 - 2009

Study of the therapeutic potential of HO-1 and its metabolite CO in avoiding immunological fetal rejection in murine models of pregnancy complications. Deutsche Forschungsgemeinschaft, ZE 526/5-1

2005 - 2008

Reprogramming of tolerance in murine models of immunological pregnancy complications using regulatory T cells. Deutsche Forschungsgemeinschaft, ZE 526/4-1