Lorenz Adrian

Prof. Dr. rer nat

Senior Scientist

Phone +49 (0) 341 235 1435
Fax +49 (0) 341 235 1443

Working group Geobiochemistry
Department Isotope Biogeochemistry
Helmholtz Centre for Environmental Research - UFZ
Permoserstraße 15, 04318 Leipzig, Germany


Curriculum Vitae

2017 - now Professorship for Geobiotechnology at TU Berlin
2013 - now Senior Scientist at UFZ Leipzig, working group Functional Genomics, since 2017 Geobiochemistry
2008 - 2013 Head of an ERC group, Department Isotope Biogeochemistry
2008 - 2010 Guest Professor for Applied Biochemistry, TU Berlin
2007 Postdoc Rensselaer Polytechnic Institute, NY, USA
2006 Habilitation, TU Berlin
2003 Postdoc Cornell University, NY, USA
1999 PhD, TU Berlin
1993 Diploma Biology, Universtät Bonn and University of Manchester, UK


For information on our research please visit our



An integrated course (lecture series + seminar) on Geobiotechnology is offered at the Institute for Biotechnology at the Technische Universität Berlin. For details see the link to TU Berlin.

From 2018 on we offer a one week lab course on geobiotechnology in our labs in Leipzig for students of the TU Berlin.

 Publication list

see also GoogleSchoolar


2019 (4)

  • Budhraja, R., Ding, C., Walter, P., Wagner, S., Reemtsma, T., Sawers, G., Adrian, L., (2019):
    The impact of species, respiration type, growth phase and genetic inventory on absolute metal content of intact bacterial cells
    Metallomics 11 (5), 925 - 935
    full text (url)
  • El-Athman, F., Adrian, L., Jekel, M., Putschew, A., (2019):
    Abiotic reductive deiodination of iodinated organic compounds and X-ray contrast media catalyzed by free corrinoids
    Chemosphere 221 , 212 - 218
    full text (url)
  • Ouyang, W.-Y., Su, J.-Q., Richnow, H.H., Adrian, L., (2019):
    Identification of dominant sulfamethoxazole-degraders in pig farm-impacted soil by DNA and protein stable isotope probing
    Environ. Int. 126 , 118 - 126
    full text (url)
  • Türkowsky, D., Lohmann, P., Mühlenbrink, M., Schubert, T., Adrian, L., Goris, T., Jehmlich, N., von Bergen, M., (2019):
    Thermal proteome profiling allows quantitative assessment of interactions between tetrachloroethene reductive dehalogenase and trichloroethene
    J. Proteomics 192 , 10 - 17
    full text (url)

2018 (17)

  • Busche, T., Hillion, M., Loi, V.V., Berg, D., Walther, B., Semmler, T., Strommenger, B., Witte, W., Cuny, C., Mellmann, A., Holmes, M.A., Kalinowski, J., Adrian, L., Bernhardt, J., Antelmann, H., (2018):
    Comparative secretome analyses of human and zoonotic Staphylococcus aureus isolates CC8, CC22, and CC398
    Mol. Cell. Proteomics 17 (12), 2412 - 2433
    full text (url)
  • Chau, A.T.T., Lee, M., Adrian, L., Manefield, M.J., (2018):
    Syntrophic partners enhance growth and respiratory dehalogenation of hexachlorobenzene by Dehalococcoides mccartyi strain CBDB1
    Front. Microbiol. 9 , art. 1927
    full text (url)
  • Chevallier, M.L., Cooper, M., Kümmel, S., Barbance, A., Le Paslier, D., Richnow, H.H., Saaidi, P.-L., Adrian, L., (2018):
    Distinct carbon isotope fractionation signatures during biotic and abiotic reductive transformation of chlordecone
    Environ. Sci. Technol. 52 (6), 3615 - 3624
    full text (url)
  • David, C., Schmid, A., Adrian, L., Wilde, A., Bühler, K., (2018):
    Production of 1,2-propanediol in photoautotrophic Synechocystis is linked to glycogen turn-over
    Biotechnol. Bioeng. 115 (2), 300 - 311
    final draft (pdf)
  • Deobald, D., Adrian, L., Schöne, C., Rother, M., Layer, G., (2018):
    Identification of a unique Radical SAM methyltransferase required for the sp3-C-methylation of an arginine residue of methyl-coenzyme M reductase
    Sci. Rep. 8 , art. 7404
    full text (url)
  • Ding, C., Enyi, F.O., Adrian, L., (2018):
    Anaerobic ammonium oxidation (anammox) with planktonic cells in a redox-stable semicontinuous stirred-tank reactor
    Environ. Sci. Technol. 52 (10), 5671 - 5681
    full text (url)
  • Gadkari, J., Goris, T., Schiffmann, C.L., Rubick, R., Adrian, L., Schubert, T., Diekert, G., (2018):
    Reductive tetrachloroethene dehalogenation in the presence of oxygen by Sulfurospirillum multivorans: physiological studies and proteome analysis
    FEMS Microbiol. Ecol. 94 (1), fix176
    full text (url)
  • Hawer, H., Ütkür, K., Arend, M., Mayer, K., Adrian, L., Brinkmann, U., Schaffrath, R., (2018):
    Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast
    PLOS One 13 (10), e0205870
    full text (url)
  • Imber, M., Huyen, N.T.T., Pietrzyk-Brzezinska, A.J., Loi, V.V., Hillion, M., Bernhardt, J., Thärichen, L., Kolšek, K., Saleh, M., Hamilton, C.J., Adrian, L., Gräter, F., Wahl, M.C., Antelmann, H., (2018):
    Protein S-bacillithiolation functions in thiol protection and redox regulation of the glyceraldehyde-3-phosphate dehydrogenase Gap in Staphylococcus aureus under hypochlorite stress
    Antioxid. Redox Signal. 28 (6), 410 - 430
    full text (url)
  • Kruse, S., Goris, T., Westermann, M., Adrian, L., Diekert, G., (2018):
    Hydrogen production by Sulfurospirillum species enables syntrophic interactions of Epsilonproteobacteria
    Nat. Commun. 9 , art. 4872
    full text (url)
  • Nowak, K.M., Marco-Urrea, E., Adrian, L., (2018):
    Markierung im mikrobiellen Stoffwechsel
    Biospektrum 24 (5), 491 - 494
    full text (url)
  • Ongey, E.L., Giessmann, R.T., Fons, M., Rappsilber, J., Adrian, L., Neubauer, P., (2018):
    Heterologous biosynthesis, modifications and structural characterization of ruminococcin-A, a lanthipeptide from the gut bacterium Ruminococcus gnavus E1, in Escherichia coli
    Front. Microbiol. 9 , art. 1688
    full text (url)
  • Schubert, T., Adrian, L., Sawers, R.G., Diekert, G., (2018):
    Organohalide respiratory chains: composition, topology and key enzymes
    FEMS Microbiol. Ecol. 94 (4), fiy035
    full text (url)
  • Seidel, K., Kühnert, J., Adrian, L., (2018):
    The complexome of Dehalococcoides mccartyi reveals its organohalide respiration-complex is modular
    Front. Microbiol. 9 , art. 1130
    full text (url)
  • Shahryari, S., Zahiri, H.S., Haghbeen, K., Adrian, L., Noghabi, K.A., (2018):
    High phenol degradation capacity of a newly characterized Acinetobacter sp. SA01: Bacterial cell viability and membrane impairment in respect to the phenol toxicity
    Ecotox. Environ. Safe. 164 , 455 - 466
    full text (url)
  • Türkowsky, D., Jehmlich, N., Diekert, G., Adrian, L., von Bergen, M., Goris, T., (2018):
    An integrative overview of genomic, transcriptomic and proteomic analyses in organohalide respiration research
    FEMS Microbiol. Ecol. 94 (3), fiy013
    full text (url)
  • Zhang, S., Adrian, L., Schüürmann, G., (2018):
    Interaction mode and regioselectivity in vitamin B12-dependent dehalogenation of aryl halides by Dehalococcoides mccartyi strain CBDB1
    Environ. Sci. Technol. 52 (4), 1834 - 1843
    full text (url)

2017 (5)

  • Frauenstein, D., Seidel, K., Adrian, L., (2017):
    SandTraps are efficient, scalable, and mild systems for harvesting, washing and concentrating cells
    J. Microbiol. Methods 132 , 106 - 111
    full text (url)
  • Hartwig, S., Dragomirova, N., Kublik, A., Türkowsky, D., von Bergen, M., Lechner, U., Adrian, L., Sawers, R.G., (2017):
    A H2-oxidizing, 1,2,3-trichlorobenzene-reducing multienzyme complex isolated from the obligately organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1
    Environ. Microbiol. Rep. 9 (5), 618 - 625
    final draft (pdf)
  • Hillion, M., Imber, M., Pedre, B., Bernhardt, J., Saleh, M., Loi, V.V., Maaß, S., Becher, D., Rosado, L.A., Adrian, L., Weise, C., Hell, R., Wirtz, M., Messens, J., Antelmann, H., (2017):
    The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress
    Sci. Rep. 7 , art. 5020
    full text (url)
  • Mortan, S.H., Martín-González, L., Vicent, T., Caminal, G., Nijenhuis, I., Adrian, L., Marco-Urrea, E., (2017):
    Detoxification of 1,1,2-trichloroethane to ethene in a bioreactor co-culture of Dehalogenimonas and Dehalococcoides mccartyi strains
    J. Hazard. Mater. 331 , 218 - 225
    full text (url)
  • Zhang, S., Wondrousch, D., Cooper, M., Zinder, S.H., Schüürmann, G., Adrian, L., (2017):
    Anaerobic dehalogenation of chloroanilines by Dehalococcoides mccartyi strain CBDB1 and Dehalobacter strain 14DCB1 via different pathways as related to molecular electronic structure
    Environ. Sci. Technol. 51 (7), 3714 - 3724
    full text (url)

2016 (14)

  • Adrian, L., Löffler, F.E., (eds., 2016):
    Organohalide-respiring bacteria
    Springer, Berlin, Heidelberg, VII, 632 pp.
    full text (url)
  • Adrian, L., Löffler, F.E., (2016):
    Organohalide-respiring bacteria—an introduction
    In: Adrian, L., Löffler, F.E., (eds.)
    Organohalide-respiring bacteria
    Springer, Berlin, Heidelberg, p. 3 - 6
    full text (url)
  • Adrian, L., Löffler, F.E., (2016):
    Outlook—the next frontiers for research on organohalide-respiring bacteria
    In: Adrian, L., Löffler, F.E., (eds.)
    Organohalide-respiring bacteria
    Springer, Berlin, Heidelberg, p. 621 - 627
    full text (url)
  • Adrian, L., Marco-Urrea, E., (2016):
    Isotopes in geobiochemistry: tracing metabolic pathways in microorganisms of environmental relevance with stable isotopes
    Curr. Opin. Biotechnol. 41 , 19 - 25
    full text (url)
  • Biderre-Petit, C., Dugat-Bony, E., Mege, M., Parisot, N., Adrian, L., Moné, A., Denonfoux, J., Peyretaillade, E., Debroas, D., Boucher, D., Peyret, P., (2016):
    Distribution of Dehalococcoidia in the anaerobic deep water of a remote meromictic crater lake and detection of Dehalococcoidia-derived reductive dehalogenase homologous genes
    PLOS One 11 (1), e0145558
    full text (url)
  • Goris, T., Schiffmann, C.L., Gadkari, J., Adrian, L., von Bergen, M., Diekert, G., Jehmlich, N., (2016):
    Proteomic data set of the organohalide-respiring Epsilonproteobacterium Sulfurospirillum multivorans adapted to tetrachloroethene and other energy substrates
    Data in Brief 8 , 637 - 642
    full text (url)
  • Krasper, L., Lilie, H., Kublik, A., Adrian, L., Golbik, R., Lechner, U., (2016):
    The MarR-type regulator Rdh2R regulates rdh gene transcription in Dehalococcoides mccartyi strain CBDB1
    J. Bacteriol. 198 (23), 3130 - 3141
    full text (url)
  • Kublik, A., Deobald, D., Hartwig, S., Schiffmann, C.L., Andrades, A., von Bergen, M., Sawers, R.G., Adrian, L., (2016):
    Identification of a multi-protein reductive dehalogenase complex in Dehalococcoides mccartyi strain CBDB1 suggests a protein-dependent respiratory electron transport chain obviating quinone involvement
    Environ. Microbiol. 18 (9), 3044 - 3056
    full text (url)
  • Laso-Pérez, R., Wegener, G., Knittel, K., Widdel, F., Harding, K.J., Krukenberg, V., Meier, D.V., Richter, M., Tegetmeyer, H.E., Riedel, D., Richnow, H.-H., Adrian, L., Reemtsma, T., Lechtenfeld, O.J., Musat, F., (2016):
    Thermophilic archaea activate butane via alkyl-coenzyme M formation
    Nature 539 (7629), 396 - 401
    final draft (pdf)
  • Lünsmann, V., Kappelmeyer, U., Benndorf, R., Martínez-Lavanchy, P.M., Taubert, A., Adrian, L., Duarte, M., Pieper, D.H., von Bergen, M., Müller, J.A., Heipieper, H.J., Jehmlich, N., (2016):
    In situ protein-SIP highlights Burkholderiaceae as key players degrading toluene by para ring hydroxylation in a constructed wetland model
    Environ. Microbiol. 18 (4), 1176 - 1186
    full text (url)
  • Schiffmann, C.L., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen, M., Jehmlich, N., (2016):
    Proteomic dataset of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    Data in Brief 7 , 253 - 256
    full text (url)
  • Schubert, T., Adrian, L., Diekert, G., (2016):
    Organohalid-Atmung bei Mikroorganismen. Anaerober Energiestoffwechsel
    Biospektrum 22 (5), 462 - 464
    full text (url)
  • Tiedt, O., Mergelsberg, M., Boll, K., Müller, M., Adrian, L., Jehmlich, N., von Bergen, M., Boll, M., (2016):
    ATP-dependent C–F bond cleavage allows the complete degradation of 4-fluoroaromatics without oxygen
    mBio 7 (4), e00990-16
    full text (url)
  • Wasmund, K., Cooper, M., Schreiber, L., Lloyd, K.G., Baker, B.J., Petersen, D.G., Jørgensen, B.B., Stepanauskas, R., Reinhardt, R., Schramm, A., Loy, A., Adrian, L., (2016):
    Single-cell genome and group-specific dsrAB sequencing implicate marine members of the class Dehalococcoidia (phylum Chloroflexi) in sulfur cycling
    mBio 7 (3), e00266-16
    full text (url)

2015 (7)

  • Algora, C., Vasileiadis, S., Wasmund, K., Trevisan, M., Krüger, M., Puglisi, E., Adrian, L., (2015):
    Manganese and iron as structuring parameters of microbial communities in Arctic marine sediments from the Baffin Bay
    FEMS Microbiol. Ecol. 91 (6), fiv056
    full text (url)
  • Cooper, M., Wagner, A., Wondrousch, D., Sonntag, F., Sonnabend, A., Brehm, M., Schüürmann, G., Adrian, L., (2015):
    Anaerobic microbial transformation of halogenated aromatics and fate prediction using electron density modeling
    Environ. Sci. Technol. 49 (10), 6018 - 6028
    full text (url)
  • Hartwig, S., Thomas, C., Krumova, N., Quitzke, V., Türkowsky, D., Jehmlich, N., Adrian, L., Sawers, R.G., (2015):
    Heterologous complementation studies in Escherichia coli with the Hyp accessory protein machinery from Chloroflexi provide insight into [NiFe]-hydrogenase large subunit recognition by the HypC protein family
    Microbiology-(UK) 161 (11), 2204 - 2219
    full text (url)
  • Lee, M., Wells, E., Wong, Y.K., Koenig, J., Adrian, L., Richnow, H.H., Manefield, M., (2015):
    Relative contributions of Dehalobacter and zerovalent iron in the degradation of chlorinated methanes
    Environ. Sci. Technol. 49 (7), 4481 - 4489
    full text (url)
  • Martín-González, L., Hatijah Mortan, S., Rosell, M., Parladé, E., Martínez-Alonso, M., Gaju, N., Caminal, G., Adrian, L., Marco-Urrea, E., (2015):
    Stable carbon isotope fractionation during 1,2-dichloropropane-to-propene transformation by an enrichment culture containing Dehalogenimonas strains and a dcpA gene
    Environ. Sci. Technol. 49 (14), 8666 - 8674
    full text (url)
  • Wasmund, K., Algora, C., Müller, J., Krüger, M., Lloyd, K.G., Reinhardt, R., Adrian, L., (2015):
    Development and application of primers for the class Dehalococcoidia (phylum Chloroflexi) enables deep insights into diversity and stratification of sub-groups in the marine subsurface
    Environ. Microbiol. 17 (10), 3540 - 3556
    full text (url)
  • Yang, C., Kublik, A., Weidauer, C., Seiwert, B., Adrian, L., (2015):
    Reductive dehalogenation of oligocyclic phenolic bromoaromatics by Dehalococcoides mccartyi strain CBDB1
    Environ. Sci. Technol. 49 (14), 8497– - 8505
    full text (url)

2014 (5)

  • Goris, T., Schubert, T., Gadkari, J., Wubet, T., Tarkka, M., Buscot, F., Adrian, L., Diekert, G., (2014):
    Insights into organohalide respiration and the versatile catabolism of Sulfurospirillum multivorans gained from comparative genomics and physiological studies
    Environ. Microbiol. 16 (11), 3562 - 3580
    full text (url)
  • Musat, N., Stryhanyuk, H., Bombach, P., Adrian, L., Audinot, J.-N., Richnow, H.H., (2014):
    The effect of FISH and CARD-FISH on the isotopic composition of 13C- and 15N-labeled Pseudomonas putida cells measured by nanoSIMS
    Syst. Appl. Microbiol. 37 (4), 267 - 276
    full text (url)
  • Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J., (2014):
    Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
    Anal. Bioanal. Chem. 406 (1), 283 - 291
    full text (url)
  • Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M., (2014):
    Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
    J. Proteomics 98 , 59 - 64
    full text (url)
  • Wasmund, K., Schreiber, L., Lloyd, K.G., Petersen, D.G., Schramm, A., Stepanauskas, R., Jørgensen, B.B., Adrian, L., (2014):
    Genome sequencing of a single cell of the widely distributed marine subsurface Dehalococcoidia, phylum Chloroflexi
    ISME J. 8 (2), 383 - 397
    full text (url)

2013 (9)

  • Algora, C., Gründger, F., Adrian, L., Damm, V., Richnow, H.-H., Krüger, M., (2013):
    Geochemistry and microbial populations in sediments of the Northern Baffin Bay, Arctic
    Geomicrobiol. J. 30 (8), 690 - 705
    full text (url)
  • Duan, T.H., Adrian, L., (2013):
    Enrichment of hexachlorobenzene and 1,3,5-trichlorobenzene transforming bacteria from sediments in Germany and Vietnam
    Biodegradation 24 (4), 513 - 520
    full text (url)
  • Hug, L.A., Maphosa, F., Leys, D., Löffler, F.E., Smidt, H., Edwards, E.A., Adrian, L., (2013):
    Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases
    Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), art. 20120322
    full text (url)
  • Leys, D., Adrian, L., Smidt, H., (2013):
    Organohalide respiration: microbes breathing chlorinated molecules
    Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), 20120316
    full text (url)
  • Löffler, F.E., Yan, J., Ritalahti, K.M., Adrian, L., Edwards, E.A., Konstantinidis, K.T., Müller, J.A., Fullerton, H., Zinder, S.H., Spormann, A.M., (2013):
    Dehalococcoides mccartyi gen. nov., sp. nov., obligately organohalide-respiring anaerobic bacteria relevant to halogen cycling and bioremediation, belong to a novel bacterial class, Dehalococcoidia classis nov., order Dehalococcoidales ord. nov. and family Dehalococcoidaceae fam. nov., within the phylum Chloroflexi
    Int. J. Syst. Evol. Microbiol. 63 (2), 625 - 635
    full text (url)
  • Pöritz, M., Goris, T., Wubet, T., Tarkka, M.T., Buscot, F., Nijenhuis, I., Lechner, U., Adrian, L., (2013):
    Genome sequences of two dehalogenation specialists - Dehalococcoides mccartyi strains BTF08 and DCMB5 enriched from the highly polluted Bitterfeld region
    FEMS Microbiol. Lett. 343 (2), 101 - 104
    full text (url)
  • Puglisi, E., Trevisan, M., Grotenhuis, T., Adrian, L., (2013):
    EUROSOIL 2012 bioremediation session: preface to special issue
    Biodegradation 24 (4), 451 - 453
    full text (url)
  • Schipp, C.-J., Marco-Urrea, E., Kublik, A., Seifert, J., Adrian, L., (2013):
    Organic cofactors in the metabolism of Dehalococcoides mccartyi strains
    Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), 20120321
    full text (url)
  • Tang, S., Chan, W.W.M., Fletcher, K.E., Seifert, J., Liang, X., Löffler, F.E., Edwards, E.A., Adrian, L., (2013):
    Functional characterization of reductive dehalogenases using blue native polyacrylamide gel electrophoresis
    Appl. Environ. Microb. 79 (3), 974 - 981
    full text (url)

2012 (4)

  • Adrian, L., Vogt, C., Richnow, H.-H., (2012):
    Geochemical processes contributing to electrical currents in microbial fuel cells
    1st UFZ Energy Days 2012: 4-5 April 2012 ; book of abstracts
    UFZ-Bericht 6/2012
    Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, p. 53
    full text (pdf)
  • Kadirova, G.K., Andreevich, K.A., Adrian, L., Bakhtiyor, R., (2012):
    Functioning of salt tolerant Anabaena variabilis and Nostoc calcicola strains in salt stress, destructors of hexachlorocyclohexane (HCH) in saline conditions
    Environment and Natural Resources Research 2 (1), 63 - 72
    full text (url)
  • Marco-Urrea, E., Seifert, J., von Bergen, M., Adrian, L., (2012):
    Stable isotope peptide mass spectrometry to decipher amino acid metabolism in Dehalococcoides strain CBDB1
    J. Bacteriol. 194 (16), 4169 - 4177
    full text (url)
  • Wagner, A., Cooper, M., Ferdi, S., Seifert, J., Adrian, L., (2012):
    Growth of Dehalococcoides mccartyi strain CBDB1 by reductive dehalogenation of brominated benzenes to benzene
    Environ. Sci. Technol. 46 (16), 8960 - 8968
    full text (url)

2011 (3)

  • Marco-Urrea, E., Nijenhuis, I., Adrian, L., (2011):
    Transformation and carbon isotope fractionation of tetra- and trichloroethene to Trans-Dichloroethene by Dehalococcoides sp. strain CBDB1
    Environ. Sci. Technol. 45 (4), 1555 - 1562
    full text (url)
  • Marco-Urrea, E., Paul, S., Khodaverdi, V., Seifert, J., von Bergen, M., Kretzschmar, U., Adrian, L., (2011):
    Identification and characterization of a Re-Citrate synthase in Dehalococcoides strain CBDB1
    J. Bacteriol. 193 (19), 5171 - 5178
    full text (url)
  • Prieto, A., Möder, M., Rodil, R., Adrian, L., Marco-Urrea, E., (2011):
    Degradation of the antibiotics norfloxacin and ciprofloxacin by a white-rot fungus and identification of degradation products
    Bioresour. Technol. 102 (23), 10987 - 10995
    full text (url)

2010 (4)

  • Hölscher, T., Breuer, U., Adrian, L., Harms, H., Maskow, T., (2010):
    Production of the chiral compound (R)-3-Hydroxybutyrate by a genetically engineered methylotrophic bacterium
    Appl. Environ. Microb. 76 (16), 5585 - 5591
    full text (url)
  • Hölscher, T., Lisec, J., Baani, M., Duan, T.H., Adrian, L., (2010):
    Bacterial cultures preferentially removing singly flanked chlorine substituents from chlorobenzenes
    Environ. Sci. Technol. 44 (23), 8936 - 8942
    full text (url)
  • Kretzschmar, U., Khodaverdi, V., Adrian, L., (2010):
    Transcriptional regulation of the acetyl-CoA synthetase gene acsA in Pseudomonas aeruginosa
    Arch. Microbiol. 192 (8), 685 - 690
    full text (url)
  • Rasulov, B.A., Kim, A.A., Adrian, L., Yadgarov, K.T., (2010):
    Biodegradation of tritium labeled polychlorinated biphenyls (PCBs)by local salt tolerant mesophylic bacillus strains
    Journal of Environmental Protection 1 (4), 420 - 425
    full text (url)

2009 (4)

  • Adrian, L., (2009):
    ERC-group microflex: microbiology of Dehalococcoides-like Chloroflexi
    Reviews in Environmental Science and Biotechnology 8 (3), 225 - 229
    full text (url)
  • Adrian, L., Dudková, V., Demnerová, K., Bedard, D.L., (2009):
    "Dehalococcoides" sp. strain CBDB1 extensively dechlorinates the commercial polychlorinated biphenyl mixture aroclor 1260
    Appl. Environ. Microb. 75 (13), 4516 - 4524
    full text (url)
  • Adrian, L., Reinhardt, R., Kube, M., (2009):
    Genomics as a tool to analyze bioremediation potentials and functional diversification in subsurface environments
    Geochim. Cosmochim. Acta 73 (13 Suppl.), A12
    full text (url)
  • Wagner, A., Adrian, L., Kleinsteuber, S., Andreesen, J.R., Lechner, U., (2009):
    Transcription analysis of genes encoding homologues of reductive dehalogenases in "Dehalococcoides" sp. strain CBDB1 by using terminal restriction fragment length polymorphism and quantitative PCR
    Appl. Environ. Microb. 75 (7), 1876 - 1884
    full text (url)

2007 (3)

  • Adrian, L., Hansen, S.K., Fung, J.M., Gorisch, H., Zinder, S.H., (2007):
    Growth of Dehalococcoides strains with chlorophenols as electron acceptors
    Environ. Sci. Technol. 41 (7), 2318 - 2323
    full text (url)
  • Adrian, L., Rahnenführer, J., Gobom, J., Hölscher, T., (2007):
    Identification of a chlorobenzene reductive dehalogenase in Dehalococcoides sp. strain CBDB1
    Appl. Environ. Microb. 73 (23), 7717 - 7724
    full text (url)
  • Fung, J.M., Morris, R.M., Adrian, L., Zinder, S.H., (2007):
    Expression of reductive dehalogenase genes in Dehalococcoides ethenogenes strain 195 growing on tetrachloroethene, trichloroethene, or 2,3-dichlorophenol
    Appl. Environ. Microb. 73 (14), 4439 - 4445
    full text (url)

2005 (2)

  • Kube, M., Beck, A., Zinder, S.H., Kuhl, H., Reinhardt, R., Adrian, L., (2005):
    Genome sequence of the chlorinated compound respiring bacterium Dehalococcoides species strain CBDB1
    Nat. Biotechnol. 23 (10), 1269 - 1273
    full text (url)
  • Seshadri, R., Adrian, L., Fouts, D.E., Eisen, J.A., Phillippy, A.M., Methe, B.A., Ward, N.L., Nelson, W.C., Deboy, R.T., Khouri, H.M., Kolonay, J.F., Dodson, R.J., Daugherty, S.C., Brinkac, L.M., Sullivan, S.A., Madupu, R., Nelson, K.T., Kang, K.H., Impraim, M., Tran, K., Robinson, J.M., Forberger, H.A., Fraser, C.M., Zinder, S.H., Heidelberg, J.F., (2005):
    Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes
    Science 307 (5706), 105 - 108
    full text (url)

2004 (7)

  • Adrian, L., Lechner, U., (2004):
    Anaerobic transformation of chlorinated dioxins by microorganisms
    Organohalogen Compounds 66 , 2241 - 2246
    full text (url)
  • Adrian, L., Lechner, U., (2004):
    Reductive dehalogenation of polychlorinated benzenes and dioxins
    In: Nakano, M.M., Zuber, P., (eds.)
    Strict and facultative anaerobes: medical and environmental aspects
    Horizon Bioscience, Wymondham, Norfolk, p. 303 - 316
  • Griebler, C., Adrian, L., Meckenstock, R.U., Richnow, H.H., (2004):
    Stable carbon isotope fractionation during aerobic and anaerobic transformation of trichlorobenzene
    FEMS Microbiol. Ecol. 48 (3), 313 - 321
    full text (url)
  • Hölscher, T., Krajmalnik-Brown, R., Ritalahti, K.M., von Wintzingerode, F., Gorisch, H., Löffler, F.E., Adrian, L., (2004):
    Multiple nonidentical reductive-dehalogenase-homologous genes are common in Dehalococcoides
    Appl. Environ. Microb. 70 (9), 5290 - 5297
    full text (url)
  • Jayachandran, G., Görisch, H., Adrian, L., (2004):
    Studies on hydrogenase activity and chlorobenzene respiration in Dehalococcoides sp. strain CBDB1
    Arch. Microbiol. 182 (6), 498 - 504
    full text (url)
  • Lechner, U., Bunge, M., Adrian, L., (2004):
    Reduktive Dehalogenierung von chlorierten Benzolen und Dioxinen durch Dehalococcoides
    Biospektrum 10 (5), 630 - 632
    full text (url)
  • Rosenthal, H., Adrian, L., Steiof, M., (2004):
    Dechlorination of PCE in the presence of Fe0 enhanced by a mixed culture containing two Dehalococcoides strains
    Chemosphere 55 (5), 661 - 669
    full text (url)

2003 (5)

  • Bunge, M., Adrian, L., Kraus, A., Opel, M., Lorenz, W.G., Andreesen, J.R., Görisch, H., Lechner, U., (2003):
    Reductive dehalogenation of chlorinated dioxins by an anaerobic bacterium
    Nature 421 (6921), 357 - 360
    full text (url)
  • Hölscher, T., Görisch, H., Adrian, L., (2003):
    Reductive dehalogenation of chlorobenzene congeners in cell extracts of Dehalococcoides sp. strain CBDB1
    Appl. Environ. Microb. 69 (5), 2999 - 3001
    full text (url)
  • Jayachandran, G., Görisch, H., Adrian, L., (2003):
    Dehalorespiration with hexachlorobenzene and pentachlorobenzene by Dehalococcoides sp. strain CBDB1
    Arch. Microbiol. 180 (6), 411 - 416
    full text (url)
  • Meyer, B.C., Jacksche, J., Adrian, L., (2003):
    Indicators for landscape sustainability of farms
    In: Mander, U., Antrop, M., (eds.)
    Multifunctional landscapes. Volume III: Continuity and change
    Advances in Ecological Sciences 16
    WIT Press, Southampton, p. 79 - 94
  • Moreno Horn, M., Garbe, L.-A., Tressl, R., Adrian, L., Görisch, H., (2003):
    Biodegradation of bis(1-chloro-2-propyl) ether via initial ether scission and subsequent dehalogenation by Rhodococcus sp. strain DTB
    Arch. Microbiol. 179 (4), 234 - 241
    full text (url)

2002 (2)

  • Adrian, L., Görisch, H., (2002):
    Transformation chlororganischer Verbindungen durch Dehalococcoides-Species
    BIOforum 25 (5), 2 - 3
  • Adrian, L., Görisch, H., (2002):
    Microbial transformation of chlorinated benzenes under anaerobic conditions
    Res. Microbiol. 153 (3), 131 - 137
    full text (url)

2001 (2)

  • Hauck, R., Adrian, L., Wendler, P., Amidjojo, M., Hegemann, W., Görisch, H., (2001):
    Transformation of 2,2'-dichlorodiisopropyl ether in mixed and pure culture
    Appl. Microbiol. Biotechnol. 56 (3-4), 491 - 495
    full text (url)
  • Yoo, E.S., Libra, J., Adrian, L., (2001):
    Mechanism of decolorization of azo dyes in anaerobic mixed culture
    J. Environ. Eng.-ASCE 127 (9), 844 - 849
    full text (url)

2000 (2)

  • Adrian, L., Szewzyk, U., Görisch, H., (2000):
    Bacterial growth based on reductive dechlorination of trichlorobenzenes
    Biodegradation 11 (1), 73 - 81
    full text (url)
  • Adrian, L., Szewzyk, U., Wecke, J., Görisch, H., (2000):
    Bacterial dehalorespiration with chlorinated benzenes
    Nature 408 (6812), 580 - 583
    full text (url)

1998 (1)

  • Adrian, L., Manz, W., Szewzyk, U., Görisch, H., (1998):
    Physiological characterization of a bacterial consortium reductively dechlorinating 1,2,3- and 1,2,4-trichlorobenzene
    Appl. Environ. Microb. 64 (2), 496 - 503