Publication Details |
Category | Text Publication |
Reference Category | Journals |
DOI | 10.1098/rstb.2012.0322 |
Title (Primary) | Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases |
Author | Hug, L.A.; Maphosa, F.; Leys, D.; Löffler, F.E.; Smidt, H.; Edwards, E.A.; Adrian, L.
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Source Titel | Philosophical Transactions of the Royal Society B-Biological Sciences |
Year | 2013 |
Department | ISOBIO |
Volume | 368 |
Issue | 1616 |
Page From | art. 20120322 |
Language | englisch |
Supplements | https://royalsocietypublishing.org/action/downloadSupplement?doi=10.1098%2Frstb.2012.0322&file=rstb20120322supp1.pdf |
Keywords | organohalide respiration; reductive dehalogenase; phylogenetics |
UFZ wide themes | ru3 |
Abstract | Organohalide respiration is an anaerobic bacterial respiratory process that uses halogenated hydrocarbons as terminal electron acceptors during electron transport-based energy conservation. This dechlorination process has triggered considerable interest for detoxification of anthropogenic groundwater contaminants. Organohalide-respiring bacteria have been identified from multiple bacterial phyla, and can be categorized as obligate and non-obligate organohalide respirers. The majority of the currently known organohalide-respiring bacteria carry multiple reductive dehalogenase genes. Analysis of a curated set of reductive dehalogenases reveals that sequence similarity and substrate specificity are generally not correlated, making functional prediction from sequence information difficult. In this article, an orthologue-based classification system for the reductive dehalogenases is proposed to aid integration of new sequencing data and to unify terminology. |
Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=13590 |
Hug, L.A., Maphosa, F., Leys, D., Löffler, F.E., Smidt, H., Edwards, E.A., Adrian, L. (2013): Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), art. 20120322 10.1098/rstb.2012.0322 |