Nadine Hellmold
Contact / Address:
Phone: 0341 60252610 (Zoom Voice)
Office: Building 1.0, Room 106
Curriculum Vitae
| 2025- present | PostDoc at UFZ Leipzig, MEB, SOMA |
| 2021-2025 | Ph.D. student at UFZ Leipzig |
| 2016-2019 | Master of Science in Biotechnology; TU Berlin |
| 2011-2015 | Bachelor of Science in Biosystems Engineering; OvGU Magdeburg |
Research
My research focuses on the anaerobically growing Dehalococcoides mccartyi strain CBDB1. This organism uses halogenated, persistent environmental toxins as final electron acceptor in its respiration. This process is described as reductive dehalogenation and is catalysed by a membrane bound protein complex (OHR- complex). Anaerobic reductive dehalogenation is to date the most effective biological process to degrade these halogenated toxins.
Overall objective in my project is to make the OHR- complex from CBDB1 accessible for biotechnological applications. Therefor the complex should be biochemically and structurally described.
Raised funding
01/2021 - 07/2021 TU Berlin Anschubfinanzierung (Scope: ~20.000€)
01/2024 - 07/2024 TU Berlin Promotionsabschlusstipendium (Scope: 9.000€)
Index:
You could use our publication index for further requests.
2024 (2)
- Deobald, D., Hellmold, N., Eberwein, M., Adrian, L. (2024):
Proton motive force generation in Dehalococcoides mccartyi strain CBDB1 through intracellular proton uptake during organohalide respiration
FEBS Open Bio 14 (S2), 199 - 200 10.1002/2211-5463.13837 - Eberwein, M., Hellmold, N., Frank, R., Deobald, D., Adrian, L. (2024):
Reductive dehalogenase of Dehalococcoides mccartyi strain CBDB1 reduces cobalt-containing metal complexes enabling anodic respiration
Front. Microbiol. 15 , art. 1457014 10.3389/fmicb.2024.1457014
2023 (1)
- Hellmold, N., Eberwein, M., Phan, M.H.T., Kümmel, S., Einsle, O., Deobald, D., Adrian, L. (2023):
Dehalococcoides mccartyi strain CBDB1 takes up protons from the cytoplasm to reductively dehalogenate organohalides indicating a new modus of proton motive force generation
Front. Microbiol. 14 , art. 1305108 10.3389/fmicb.2023.1305108