Simon Klaes
Curriculum Vitae
2021 - present |
Ph.D. student, DFG Research Training Group Urban Water Interfaces (UWI) |
2018 - 2021 | Master of Science, Institute of Food Technology and Food Chemistry, Technische Universität Berlin, Germany |
2013 - 2018 | Bachelor of Science, Institute of Food Technology and Food Chemistry, Technische Universität Berlin, Germany |
Research
My research focuses on the microbial transformation of mobile halogenated aromatic compounds in redox gradients of urban hyporheic zones. Among these compounds are highly consumed pharmaceuticals like sitagliptin, diclofenac, hydrochlorothiazide, and lamotrigine which are only poorly removed by municipal wastewater treatment plants. Thus, they might accumulate in partially closed urban water cycles like the Berlin water system. However, the hyporheic zone, located at the upper part of a river bed, is a highly active natural bioreactor referred to as the river's liver. Steep redox gradients in the zone provide diverse conditions for the transformation of chemicals which can be particularly valuable if the mineralization of a compound needs sequential transformation steps under different redox conditions. Hence, I hypothesize that the hyporheic zone significantly contributes to the transformation of mobile halogenated aromatics. To investigate transformation processes and corresponding microbial communities, I use mass spectrometry and protein-based stable isotope probing.
Index:
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2024 (1)
- Klaes, S., Madan, S., Deobald, D., Cooper, M., Adrian, L. (2024):
Revealing taxonomy, activity, and substrate assimilation in mixed bacterial communities by GroEL-proteotyping-based stable isotope probing
iScience 27 (12), art. 111249 10.1016/j.isci.2024.111249
2023 (3)
- Barrero-Canosa, J., Wang, L., Oyugi, A., Klaes, S., Fischer, P., Adrian, L., Szewzyk, U., Cooper, M. (2023):
Characterization of phage vB_EcoS-EE09 infecting E. coli DSM613 isolated from wastewater treatment plant effluent and comparativepProteomics of the infected and non-infected host
Microorganisms 11 (11), art. 2688 10.3390/microorganisms11112688 - Klaes, S., Adrian, L. (2023):
Proteomics data of Escherichia phage vB_EcoS-EE09 isolated from wastewater treatment plant effluent and its infected and non-infected host E. coli DSM613. Project PXD046455 [Data set]
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD046455 - Klaes, S., Madan, S., Deobald, D., Cooper, M., Adrian, L. (2023):
GroEL-proteotyping of bacterial communities using tandem mass spectrometry
Int. J. Mol. Sci. 24 (21), art. 15692 10.3390/ijms242115692