Centre for Chemical Microscopy

The ProVIS - Centre for Chemical Microscopy is an unique research platform that combines high resolution structural and chemical imaging with high resolution mass spectrometry for metabolomics, proteomics and metallomics. The mission of ProVIS is to identify and characterize (bio)-chemical processes driven by microorganisms in soil, water, plants, human tissue and blood.

ProVIS provides access to scientific instrumentation and laboratory facilities with expert guidance and support to enable collaborative and multidisciplinary research. We welcome users from academia and industry.

Your Experiment in ProVIS

Procedure for running an experiment at ProVIS:

  1. Contact us and discuss your idea with us
  2. Fill and sign the application form and send it to
  3. Await notification of approval or rejection from scientific panel in ProVIS within the following month.

Expert Groups and Equipment

  • Bruker SolariX 12T FT-ICR mass spectrometer
  • Bruker Autoflex Speed MALDI-ToF mass spectrometer


Zeiss Merlin VP Compact

Zeiss Merlin VP Compact

Field-emitting scanning electron microscope with Bruker Quantax XFlash Flat Quad energy-dispersive X-ray spectrometer.

  • high-resolution imaging (SE, BSE, STEM)
  • elemental nano-analytics
Zeiss Orion NanoFab

Zeiss Orion NanoFab

Scanning helium ion microscope equipped with electron-flood gun for charge compensation and gas-injection system.

  • high-resolution imaging (SE detection)
  • nano-fabrication (ion-milling with He or Ne)
WITec Alpha 300 RA, confocal Raman microscope with AFM option

WITec Alpha 300RA

Confocal Raman microscope with AFM. Excitation: solid state lasers 532nm, 785nm and He-Ne laser. Equipped with True Surface option.

  • acquisition of Raman spectra
  • chemical mapping
  • high-resolution atomic force microscopy


Dr. Matthias Schmidt

+49 341 235 1358

  • Cameca nanoSIMS 50L sector-field secondary ion mass spectrometer
  • IONTOF ToF.SIMS.5 time-of-flight secondary ion mass spectrometer

nanoSIMS 50L

Dr. Hryhoriy Stryhanyuk
+49 341 235 1359

  • High-resolution mass spectrometry of peptides and proteins (global analysis or gel-bands)
  • Analysis of peptide derivatization
  • Analysis of isotope incorporation into peptides
  • Instrument: LC-MS/MS (Orbitrap Fusion) coupled via an Advion
  • We are happy to measure in scientific cooperations but we also offer commercial analyses. Do not hesitate to contact us ( if you are interested.

  • Neptune Multiple-collector inductively coupled plasma mass spectrometry (Neptune MC-ICPMS, Thermo Fisher Scientific) with Trace 1310 GC (gas chromatography, Thermo Fisher Scientific)

Contact persons:

Dr. Matthias Gehre
+ 49 (0) 341 235 1361

Dr. Steffen Kümmel
+ 49 (0) 341 235 1362