Dr. Niculina Musat
Contact / Addess:
Phone +49 (0) 341 235 4656
Fax +49 (0) 341 235 450822
Helmholtz Centre for Environmental Research - UFZ
Permoserstrasse 15
04318 Leipzig
Curriculum Vitae
| Since April 2012 |
Scientific Head of Centre for Chemical Microscopy (ProVIS) Helmholtz Centre for Environmental Research – UFZ Department of Isotope Biogeochemistry |
| 2008 - 2012 |
Scientist Max-Planck Institute for Marine Microbiology, Bremen, Germany |
| 2006 - 2008 |
Post-Doctoral Fellow Max-Planck Institute for Marine Microbiology, Bremen, Germany. |
|
June 2006 |
Ph.D. in Life Sciences (Dr.rer.nat) University of Bremen and Max-Planck Institute, Bremen, Germany |
|
Apr. - Dec. 2001 |
Research Assistant, National Institute for Research and Development in Physics and Nuclear Engineering, ‘Horia-Hulubei’, Romania |
| 2000 - 2001 |
Research Assistant University of Bucharest, Faculty of Biology (half-time job) |
| 2000 - 2001 |
Biologist Shigella – Pseudomonas Department, Cantacuzino Institute, Bucharest, Romania |
|
Feb. 2001 |
M.Sc. in Microbiology and Microbial Genetics University of Bucharest, Faculty of Biology, Romania |
|
Jul. 1999 |
B.Sc. in Biology University of Bucharest, Faculty of Biology, Romania |
Field of Expertise
- Microbial Ecology and Ecophysiology
- Single cell imaging techniques (FISH, CARD-FISH, NanoSIMS, Laser dissection microscopy - LMD)
- Inter-species nutritional interactions
- Stable isotope probing (SIP) to trace cellular metabolic activity and cell to cell metabolic interactions
- SIP-Nano-scale Secondary Ion Mass Spectrometry (NanoSIMS) applications in microbiology/biology
- Correlative microscopy, chemical imaging and underlying sample preparation concepts and techniques for environmental samples
Main Research Interests
- Inter-species nutritional interactions in microbial associations, including nutrient transfer between autotrophic and heterotrophic communities in fresh water and marine environments, trophic interactions in multi-species assemblages, and symbiotic associations.
- Development of new correlative imaging approaches for visualization, identification and chemical mapping of microbial cells and sub-cellular components. These include species identification and visualization by fluorescence microscopy (FISH &CARD-FISH), high resolution structure imaging (SEM, TEM, HIM) and high resolution chemical mapping (nanoSIMS, ToFSIMS, Raman microspectroscopy, EDX).
- Impact and fate of antibiotics in natural environments: effect of antibiotics on the metabolism of natural microbial communities, impact on single-cell metabolism, dynamics of environmental communities under antibiotic stress, biodegradation/biotransformation of antibiotics by microorganisms.
- Microbe-plant nutritional interactions in the rhizosphere, including colonization of Zea mays roots by soil microorganisms and transfer of carbon between roots and associated microorganisms.
Publications
Theses
M.Sc. thesis: “Comparative analyses of Pseudomonas aeruginosa strains isolated from clinical products and natural environments.” University of Bucharest, Romania (February 2001)
Ph.D thesis: “Molecular characterization of symbiotic associations between chemoautotrophic sulphur-oxidizing microorganisms and nematodes in shallow marine sediments”. University of Bremen and Max-Planck Institute, Bremen, Germany (June 2006)
Index:
2022 (4)2021 (7)
2020 (5)
2019 (7)
2018 (4)
2017 (3)
2016 (3)
2015 (4)
2014 (2)
2013 (3)
2012 (2)
You could use our publication index for further requests.
2022 (4)
- Arandia-Gorostidi, N., Berthelot, H., Calabrese, F., Stryhanyuk, H., Klawonn, I., Iversen, M., Nahar, N., Grossart, H.-P., Ploug, H., Musat, N. (2022):
Efficient carbon and nitrogen transfer from marine diatom aggregates to colonizing bacterial groups
Sci. Rep. 12 , art. 14949
full text (doi) - Chakaroun, R., Massier, L., Musat, N., Kovacs, P. (2022):
New paradigms for familiar diseases: Lessons learned on circulatory bacterial signatures in cardiometabolic diseases
Exp. Clin. Endocrinol. Diabet. 130 (5), 313 - 326
full text (doi) - Malyi, T., Tsiumra, V., Vistovskyy, V., Mitina, N., Musat, N., Stryhanyuk, H., Kondyr, A., Zaichenko, A., Voloshinovskii, A. (2022):
Template synthesis of luminescent oligoperoxide coated YBO3 nanoparticles doped with Ce3+, Tb3+ and Eu3+ ions
Opt. Mater. 124 , art. 112008
full text (doi) - Tamisier, M., Schmidt, M., Vogt, C., Kümmel, S., Stryhanyuk, H., Musat, N., Richnow, H.-H., Musat, F. (2022):
Iron corrosion by methanogenic archaea characterized by stable isotope effects and crust mineralogy
Environ. Microbiol. 24 (2), 583 - 595
full text (doi)
2021 (7)
- Bandara, C.D., Schmidt, M., Davoudpour, Y., Stryhanyuk, H., Richnow, H.H., Musat, N. (2021):
Microbial identification, high-resolution microscopy and spectrometry of the rhizosphere in its native spatial context
Front. Plant Sci. 12 , art. 668929
full text (doi) - Calabrese, F., Stryhanyuk, H., Moraru, C., Schlömann, M., Wick, L.Y., Richnow, H.H., Musat, F., Musat, N. (2021):
Metabolic history and metabolic fitness as drivers of anabolic heterogeneity in isogenic microbial populations
Environ. Microbiol. 23 (11), 6764 - 6776
full text (doi) - Chakaroun, R.M., Massier, L., Heintz-Buschart, A., Said, N., Fallmann, J., Crane, A., Schütz, T., Dietrich, A., Blüher, M., Stumvoll, M., Musat, N., Kovacs, P. (2021):
Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery
Genome Med. 13 , art. 105
full text (doi) - Chen, S.-C., Budhraja, R., Adrian, L., Calabrese, F., Stryhanyuk, H., Musat, N., Richnow, H.-H., Duan, G.-L., Zhu, Y.-G., Musat, F. (2021):
Novel clades of soil biphenyl degraders revealed by integrating isotope probing, multi-omics, and single-cell analyses
ISME J. 15 (12), 3508 - 3521
full text (doi) - Decelle, J., Veronesi, G., LeKieffre, C., Gallet, B., Chevalier, F., Stryhanyuk, H., Marro, S., Ravanel, S., Tucoulou, R., Schieber, N., Finazzi, G., Schwab, Y., Musat, N. (2021):
Subcellular architecture and metabolic connection in the planktonic photosymbiosis between Collodaria (radiolarians) and their microalgae
Environ. Microbiol. 23 (11), 6569 - 6586
full text (doi) - Imihami Mudiyanselage, C.C.D.B., Schmidt, M., Davoudpour, Y., Stryhanyuk, H., Richnow, H., Musat, N. (2021):
High-resolution chemical mapping and identifying spatial distribution of microbes in the Zea mays rhizosphere using correlative microscopy
EGU General Assembly 2021, online, 19–30 Apr 2021
EGUsphere
Copernicus Publications, p. EGU21-12160
full text (doi) - Uwizeye, C., Mars Brisbin, M., Gallet, B., Chevalier, F., LeKieffre, C., Schieber, N.L., Falconet, D., Wangpraseurt, D., Schertel, L., Stryhanyuk, H., Musat, N., Mitarai, S., Schwab, Y., Finazzi, G., Decelle, J. (2021):
Cytoklepty in the plankton: A host strategy to optimize the bioenergetic machinery of endosymbiotic algae
Proc. Natl. Acad. Sci. U.S.A. 118 (27), e2025252118
full text (doi)
2020 (5)
- Arandia‐Gorostidi, N., Alonso‐Sáez, L., Stryhanyuk, H., Richnow, H.H., Morán, X.A.G., Musat, N. (2020):
Warming the phycosphere: Differential effect of temperature on the use of diatom‐derived carbon by two copiotrophic bacterial taxa
Environ. Microbiol. 22 (4), 1381 - 1396
full text (doi) - Benettoni, P., Ye, J.-Y., Holbrook, T.R., Calabrese, F., Wagner, S., Zarejousheghani, M., Griebel, J., Ullrich, M.K., Musat, N., Schmidt, M., Flyunt, R., Reemtsma, T., Richnow, H.-H., Stryhanyuk, H. (2020):
Surface cleaning and sample carrier for complementary high-resolution imaging techniques
Biointerphases 15 (2), art. 021005
full text (doi) - Davoudpour, Y., Schmidt, M., Calabrese, F., Richnow, H.H., Musat, N. (2020):
High resolution microscopy to evaluate the efficiency of surface sterilization of Zea Mays seeds
PLOS One 15 (11), e0242247
full text (doi) - Decelle, J., Veronesi, G., Gallet, B., Stryhanyuk, H., Benettoni, P., Schmidt, M., Tucoulou, R., Passarelli, M., Bohic, S., Clode, P., Musat, N. (2020):
Subcellular chemical imaging: New avenues in cell biology
Trends Cell Biol. 30 (3), 173 - 188
full text (doi) - Massier, L., Chakaroun, R., Tabei, S., Crane, A., Didt, K.D., Fallmann, J., von Bergen, M., Haange, S.-B., Heyne, H., Stumvoll, M., Gericke, M., Dietrich, A., Blüher, M., Musat, N., Kovacs, P. (2020):
Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes
Gut 69 (10), 1796 - 1806
full text (doi)
2019 (7)
- Calabrese, F., Voloshynovska, I., Musat, F., Thullner, M., Schlömann, M., Richnow, H.H., Lambrecht, J., Müller, S., Wick, L.Y., Musat, N., Stryhanyuk, H. (2019):
Quantitation and comparison of phenotypic heterogeneity among single cells of monoclonal microbial populations
Front. Microbiol. 10 , art. 2814
full text (doi) - Cassarini, C., Bhattarai, S., Rene, E.R., Vogt, C., Musat, N., Esposito, G., Lens, P.N.L. (2019):
Enrichment of anaerobic methanotrophs in biotrickling filters using different sulfur compounds as electron acceptor
Environ. Eng. Sci. 36 (4), 431 - 443
full text (doi) - Cassarini, C., Rene, E.R., Bhattarai, S., Vogt, C., Musat, N., Lens, P.N.L. (2019):
Anaerobic methane oxidation coupled to sulfate reduction in a biotrickling filter: Reactor performance and microbial community analysis
Chemosphere 236 , art. 124290
full text (doi) - Chen, S.-C., Musat, N., Lechtenfeld, O.J., Paschke, H., Schmidt, M., Said, N., Popp, D., Calabrese, F., Stryhanyuk, H., Jaekel, U., Zhu, Y.-G., Joye, S.B., Richnow, H.-H., Widdel, F., Musat, F. (2019):
Anaerobic oxidation of ethane by archaea from a marine hydrocarbon seep
Nature 568 (7750), 108 - 111
full text (doi) - Decelle, J., Stryhanyuk, H., Gallet, B., Veronesi, G., Schmidt, M., Balzano, S., Marro, S., Uwizeye, C., Jouneau, P.-H., Lupette, J., Jouhet, J., Maillot-Maréchal, E., Schwab, Y., Schieber, N.L., Tucoulou, R., Richnow, H., Finazzi, G., Musat, N. (2019):
Algal remodeling in a ubiquitous planktonic photosymbiosis
Curr. Biol. 29 (6), 968 - 978.e4
full text (doi) - Moreno Osorio, J.H., Benettoni, P., Schmidt, M., Stryhanyuk, H., Schmitt-Jansen, M., Pinto, G., Pollio, A., Frunzo, L., Lens, P.N.L., Richnow, H.H., Esposito, G., Musat, N. (2019):
Investigation of architecture development and phosphate distribution in Chlorella biofilm by complementary microscopy techniques
FEMS Microbiol. Ecol. 95 (4), fiz029
full text (doi) - Worrich, A., Musat, N., Harms, H. (2019):
Associational effects in the microbial neighborhood
ISME J. 13 (9), 2143 - 2149
full text (doi)
2018 (4)
- Bader, M., Rossberg, A., Steudtner, R., Drobot, B., Großmann, K., Schmidt, M., Musat, N., Stumpf, T., Ikeda-Ohno, A., Cherkouk, A. (2018):
Impact of Haloarchaea on speciation of uranium—A multispectroscopic approach
Environ. Sci. Technol. 52 (12), 12895 - 12904
full text (doi) - McNichol, J., Stryhanyuk, H., Sylva, S.P., Thomas, F., Musat, N., Seewald, J.S., Sievert, S.M. (2018):
Primary productivity below the seafloor at deep-sea hot springs
Proc. Natl. Acad. Sci. U.S.A. 115 (26), 6756 - 6761
full text (doi) - Rotaru, A.-E., Calabrese, F., Stryhanyuk, H., Musat, F., Shrestha, P.M., Weber, H.S., Snoeyenbos-West, O.L.O., Hall, P.O.J., Richnow, H.H., Musat, N., Thamdrup, B. (2018):
Conductive particles enable syntrophic acetate oxidation between Geobacter and Methanosarcina from coastal sediments
mBio 9 (3), e00226-18
full text (doi) - Stryhanyuk, H., Calabrese, F., Kümmel, S., Musat, F., Richnow, H.-H., Musat, N. (2018):
Calculation of single cell assimilation rates from SIP-nanoSIMS-derived isotope ratios: a comprehensive approach
Front. Microbiol. 9 , art. 2342
full text (doi)
2017 (3)
- Bader, M., Müller, K., Foerstendorf, H., Drobot, B., Schmidt, M., Musat, N., Swanson, J.S., Reed, D.T., Stumpf, T., Cherkouk, A. (2017):
Multistage bioassociation of uranium onto an extremely halophilic archaeon revealed by a unique combination of spectroscopic and microscopic techniques
J. Hazard. Mater. 327 , 225 - 232
full text (doi) - Musat, F., Musat, N. (2017):
Measuring the impact of hydrocarbons on rates of nitrogen fixation
In: McGenity, T.J., Timmis, K.N., Nogales, B. (eds.)
Hydrocarbon and lipid microbiology protocols. Activities and phenotypes
Springer Protocols Handbooks
Springer, Berlin, Heidelberg, p. 81 - 97
full text (doi) - Worrich, A., Stryhanyuk, H., Musat, N., König, S., Banitz, T., Centler, F., Frank, K., Thullner, M., Harms, H., Richnow, H.-H., Miltner, A., Kästner, M., Wick, L.Y. (2017):
Mycelium-mediated transfer of water and nutrients stimulates bacterial activity in dry and oligotrophic environments
Nat. Commun. 8 , art. 15472
full text (doi)
2016 (3)
- Jiang, H., Kilburn, M.R., Decelle, J., Musat, N. (2016):
NanoSIMS chemical imaging combined with correlative microscopy for biological sample analysis
Curr. Opin. Biotechnol. 41 , 130 - 135
full text (doi) - Musat, N., Musat, F., Weber, P.K., Pett-Ridge, J. (2016):
Tracking microbial interactions with NanoSIMS
Curr. Opin. Biotechnol. 41 , 114 - 121
full text (doi) - Saatz, J., Stryhanyuk, H., Vetterlein, D., Musat, N., Otto, M., Reemtsma, T., Richnow, H.H., Daus, B. (2016):
Location and speciation of gadolinium and yttrium in roots of Zea mays by LA-ICP-MS and ToF-SIMS
Environ. Pollut. 216 , 245 - 252
full text (doi)
2015 (4)
- Schkolnik, G., Schmidt, M., Mazza, M.G., Harnisch, F., Musat, N. (2015):
In situ analysis of a silver nanoparticle-precipitating Shewanella biofilm by surface enhanced confocal Raman microscopy
PLOS One 10 (12), e0145871
full text (doi) - Stryhanyuk, H., Musat, N., Richnow, H.-H. (2015):
Quantitative imaging of microbial-mediated biochemical processes with secondary ion mass spectrometry
In: Daus, B., Bings, N., Leopold, K., Otto, M., Panne, U., Welz, U., Wennrich, R. (eds.)
Canas ’15. Colloquium Analytische Atomspektroskopie, 8.–11. März 2015, Helmholtz-Zentrum für Umweltforschung – UFZ Leipzig. Colloquium Analytical Atomic Spectroscopy, 8–11 March, 2015, Helmholtz Centre for Environmental Research – UFZ Leipzig
Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, p. 59 - Svedén, J.B., Adam, B., Walve, J., Nahar, N., Musat, N., Lavik, G., Whitehouse, M.J., Kuypers, M.M.M., Ploug, H. (2015):
High cell-specific rates of nitrogen and carbon fixation by the cyanobacterium Aphanizomenon sp. at low temperatures in the Baltic Sea
FEMS Microbiol. Ecol. 91 (12), fiv131
full text (doi) - Zimmermann, M., Escrig, S., Hübschmann, T., Kirf, M.K., Brand, A., Inglis, R.F., Musat, N., Müller, S., Meibom, A., Ackermann, M., Schreiber, F. (2015):
Phenotypic heterogeneity in metabolic traits among single cells of a rare bacterial species in its natural environment quantified with a combination of flow cell sorting and NanoSIMS
Front. Microbiol. 6 , art. 243
full text (doi)
2014 (2)
- Musat, N., Stryhanyuk, H., Bombach, P., Adrian, L., Audinot, J.-N., Richnow, H.H. (2014):
The effect of FISH and CARD-FISH on the isotopic composition of 13C- and 15N-labeled Pseudomonas putida cells measured by nanoSIMS
Syst. Appl. Microbiol. 37 (4), 267 - 276
full text (doi) - Sheik, A.R., Brussaard, C.P.D., Lavik, G., Lam, P., Musat, N., Krupke, A., Littmann, S., Strous, M., Kuypers, M.M.M. (2014):
Responses of the coastal bacterial community to viral infection of the algae Phaeocystis globosa
ISME J. 8 (1), 212 - 225
full text (doi)
2013 (3)
- Jaekel, U., Musat, N., Adam, B., Kuypers, M., Grundmann, O., Musat, F. (2013):
Anaerobic degradation of propane and butane by sulfate-reducing bacteria enriched from marine hydrocarbon cold seeps
ISME J. 7 (5), 885 - 895
full text (doi) - Krupke, A., Musat, N., LaRoche, J., Mohr, W., Fuchs, B.M., Amann, R.I., Kuypers, M.M.M., Foster, R.A. (2013):
In situ identification and N2 and C fixation rates of uncultivated cyanobacteria populations
Syst. Appl. Microbiol. 36 (4), 259 - 271
full text (doi) - Sheik, A.R., Brussaard, C.P.D., Lavik, G., Foster, R.A., Musat, N., Adam, B., Kuypers, M.M.M. (2013):
Viral infection of Phaeocystis globosa impedes release of chitinous star-like structures: quantification using single cell approaches
Environ. Microbiol. 15 (5), 1441 - 1451
full text (doi)
2012 (2)
- Alonso, C., Musat, N., Kuypers, M.M.M., Amann, R. (2012):
HISH–SIMS analysis of bacterial uptake of algal-derived carbon in the Río de la Plata estuary
Syst. Appl. Microbiol. 35 (8), 541 - 548
full text (doi) - Thompson, A.W., Foster, R.A., Krupke, A., Carter, B.J., Musat, N., Vaulot, D., Kuypers, M.M.M., Zehr, J.P. (2012):
Unicellular cyanobacterium symbiotic with a single-celled eukaryotic alga
Science 337 (6101), 1546 - 1550
full text (doi)