Dr. Sven-Bastiaan HaangePostdoc in der Funktionelle Metabolomik GruppeKontaktHelmholtz-Zentrum für Umweltforschung - UFZ Department Molekulare Systembiologie Permoserstr. 15, 04318 Leipzig Telefon: +49 341 235 1099 Sven Haange |
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Soziale Netzwerke
Forschungsschwerpunkte
- Mikrobiom Biologie von der intestinale Mikrobiota
- Qualitative and quantitative mikrobielle Proteomik | Metaproteomik
- Identifikation von mikrobiellen Schlüsselorganismen mit Protein-SIP
- Metabolomik von der intestinale Mikrobiota
- Metagenomik und 16S rRNA Gensequenzierung von der intestinale Mikrobiota
Lebenslauf
Seit 1.1.2019 | Postdoc in der Arbeitsgruppe Funktionelle Metabolomik |
2016 - 2018 |
Gastwissenschaftler in der AG Mikrobiom Biologie Wissenschafftlicher Mitarbeiter am Institut für Biochemie, Universität Leipzig, Leipzig |
2013 - 2016 | Doktorand am Helmholtz-Zentrum für Umweltforschung, Leipzig |
2011 - 2013 | Doktorand an der Kinderchirurgie, Universität Leipzig, Leipzig |
2006 - 2011 |
Dipl. Biochemie Universität Greifswald |
Publikationen
Inhalt:
2020 (8)2019 (3)
2018 (3)
2017 (2)
2016 (3)
2015 (2)
2013 (1)
2012 (1)
Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.
2020 (8)
- Haange, S.-B., Groeger, N., Froment, J., Rausch, T., Burkhardt, W., Gonnermann, S., Braune, A., Blaut, M., von Bergen, M., Rolle-Kampczyk, U., (2020):
Multiplexed quantitative assessment of the fate of taurine and sulfoquinovose in the intestinal microbiome
Metabolites 10 (11), art. 430
Volltext (DOI) - Haange, S.-B., Jehmlich, N., Krügel, U., Hintschich, C., Wehrmann, D., Hankir, M., Seyfried, F., Froment, J., Hübschmann, T., Müller, S., Wissenbach, D.K., Kang, K.H., Buettner, C., Panagiotou, G., Noll, M., Rolle-Kampczyk, U., Fenske, W., von Bergen, M., (2020):
Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss
Microbiome 8 , art. 13
Volltext (DOI) - Krause, J.L., Haange, S.-B., Schäpe, S.S., Engelmann, B., Rolle-Kampczyk, U., Fritz-Wallace, K., Wang, Z., Jehmlich, N., Türkowsky, D., Schubert, K., Pöppe, J., Bote, K., Rösler, U., Herberth, G., von Bergen, M., (2020):
The glyphosate formulation Roundup® LB plus influences the global metabolome of pig gut microbiota in vitro
Sci. Total Environ. 745 , art. 140932
Volltext (DOI) - Lohmann, P., Schäpe, S.S., Haange, S.-B., Oliphant, K., Allen-Vercoe, E., Jehmlich, N., von Bergen, M., (2020):
Function is what counts: how microbial community complexity affects species, proteome and pathway coverage in metaproteomics
Expert Rev. Proteomics 17 (2), 163 - 173
Volltext (DOI) - Massier, L., Chakaroun, R., Tabei, S., Crane, A., Didt, K.D., Fallmann, J., von Bergen, M., Haange, S.-B., Heyne, H., Stumvoll, M., Gericke, M., Dietrich, A., Blüher, M., Musat, N., Kovacs, P., (2020):
Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes
Gut 69 (10), 1796 - 1806
Volltext (DOI) - Mendler, A., Geier, F., Haange, S.-B., Pierzchalski, A., Krause, J.L., Nijenhuis, I., Froment, J., Jehmlich, N., Berger, U., Ackermann, G., Rolle-Kampczyk, U., von Bergen, M., Herberth, G., (2020):
Mucosal-associated invariant T-Cell (MAIT) activation is altered by chlorpyrifos- and glyphosate-treated commensal gut bacteria
J. Immunotoxicol. 17 (1), 10 - 20
Volltext (DOI) - Meyer-Cifuentes, I., Gruhl, S., Haange, S.-B., Lünsmann, V., Jehmlich, N., von Bergen, M., Heipieper, H.J., Müller, J.A., (2020):
Benzylsuccinate synthase is post-transcriptionally regulated in the toluene-degrading denitrifier Magnetospirillum sp. strain 15-1
Microorganisms 8 (5), art. 681
Volltext (DOI) - Rolle-Kampczyk, U., Gebauer, S., Haange, S.-B., Schubert, K., Kern, M., Moulla, Y., Dietrich, A., Schön, M.R., Klöting, N., von Bergen, M., Blüher, M., (2020):
Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation
Sci. Total Environ. 748 , art. 142458
Volltext (DOI)
2019 (3)
- Haange, S.-B., Jehmlich, N., Hoffmann, M., Weber, K., Lehmann, J., von Bergen, M., Slanina, J., (2019):
Disease development is accompanied by changes in bacterial protein abundance and functions in a refined model of dextran sulfate sodium (DSS)-induced colitis
J. Proteome Res. 18 (4), 1774 - 1786
Volltext (DOI) - Haange, S.-B., Jehmlich, N., Jacobi, T., von Bergen, M., (2019):
Chancen und Risiken von Metaproteomik in der Mikrobiomforschung. Opportunities and pitfalls of metaproteomics in microbiome research
Adipositas - Ursachen, Folgeerkrankungen, Therapie 13 (4), 205 - 213
Volltext (DOI) - Ke, X., Walker, A., Haange, S.-B., Lagkouvardos, I., Liu, Y., Schmitt-Kopplin, P., von Bergen, M., Jehmlich, N., He, X., Clavel, T., Cheung, P.C.K., (2019):
Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice
Mol. Metab. 22 , 96 - 109
Volltext (DOI)
2018 (3)
- Cerdó, T., Ruiz, A., Acuña, I., Jáuregui, R., Jehmlich, N., Haange, S.-B., von Bergen, M., Suárez, A., Campoy, C., (2018):
Gut microbial functional maturation and succession during human early life
Environ. Microbiol. 20 (6), 2160 - 2177
Volltext (DOI) - Chupani, L., Niksirat, H., Lünsmann, V., Haange, S.-B., von Bergen, M., Jehmlich, N., Zuskova, E., (2018):
Insight into the modulation of intestinal proteome of juvenile common carp (Cyprinus carpio L.) after dietary exposure to ZnO nanoparticles
Sci. Total Environ. 613-614 , 62 - 71
Volltext (DOI) - Russo, R., Haange, S.-B., Rolle-Kampczyk, U., von Bergen, M., Becker, J.M., Liess, M., (2018):
Identification of pesticide exposure-induced metabolic changes in mosquito larvae
Sci. Total Environ. 643 , 1533 - 1541
Volltext (DOI)
2017 (2)
- Chupani, L., Zusková, É., Niksirat, H., Panáček, A., Lünsmann, V., Haange, S.-B., von Bergen, M., Jehmlich, N., (2017):
Effects of chronic dietary exposure of zinc oxide nanoparticles on the serum protein profile of juvenile common carp (Cyprinus carpio L.)
Sci. Total Environ. 579 , 1504 - 1511
Volltext (DOI) - Oberbach, A., Haange, S.-B., Schlichting, N., Heinrich, M., Lehmann, S., Till, H., Hugenholtz, F., Kullnick, Y., Smidt, H., Frank, K., Seifert, J., Jehmlich, N., von Bergen, M., (2017):
Metabolic in vivo labeling highlights differences of metabolically active microbes from the mucosal gastrointestinal microbiome between high-fat and normal chow diet
J. Proteome Res. 16 (4), 1593 - 1604
Volltext (DOI)
2016 (3)
- Haange, S.-B., Jehmlich, N., (2016):
Proteomic interrogation of the gut microbiota: potential clinical impact
Expert Rev. Proteomics 13 (6), 535 - 537
Volltext (DOI) - Schaubeck, M., Clavel, T., Calasan, J., Lagkouvardos, I., Haange, S.B., Jehmlich, N., Basic, M., Dupont, A., Hornef, M., von Bergen, M., Bleich, A., Haller, D., (2016):
Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence
Gut 65 , 225 - 237
Volltext (DOI) - Wissenbach, D.K., Oliphant, K., Rolle-Kampczyk, U., Yen, S., Höke, H., Baumann, S., Haange, S.B., Verdu, E.F., Allen-Vercoe, E., von Bergen, M., (2016):
Optimization of metabolomics of defined in vitro gut microbial ecosystems
Int. J. Med. Microbiol. 306 (5), 280 - 289
Volltext (DOI)
2015 (2)
- Müller, S.A., Pernitzsch, S.R., Haange, S.-B., Uetz, P., von Bergen, M., Sharma, C.M., Kalkhof, S., (2015):
Stable isotope labeling by amino acids in cell culture based proteomics reveals differences in protein abundances between spiral and coccoid forms of the gastric pathogen Helicobacter pylori
J. Proteomics 126 , 34 - 45
Volltext (DOI) - Schaubeck, M., Clavel, T., Lagkouvardos, M., Calasan, J., Haange, S.B., Jehmlich, N., von Bergen, M., Basic, M., Bleich, A., Haller, D., (2015):
Transmissive Crohn's disease-like ileitis is caused by functional dysbiosis in the intestinal microbiota independent of inflammation-driven Paneth cell failure
J. Crohns Colitis 9 (Suppl. 1), S1 - S1
Volltext (DOI)
2013 (1)
- Ferrer, M., Ruiz, A., Lanza, F., Haange, S.-B., Oberbach, A., Till, H., Bargiela, R., Campoy, C., Segura, M.T., Richter, M., von Bergen, M., Seifert, J., Suarez, A., (2013):
Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure
Environ. Microbiol. 15 (1), 211 - 226
Volltext (DOI)
2012 (1)
- Haange, S.-B., Oberbach, A., Schlichting, N., Hugenholtz, F., Smidt, H., von Bergen, M., Till, H., Seifert, J., (2012):
Metaproteome analysis and molecular genetics of rat intestinal microbiota reveals section and localisation resolved species distribution and enzymatic functionalities
J. Proteome Res. 11 (11), 5406 - 5417
Volltext (DOI)