Details zur Publikation

Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1038/s41467-026-74082-0
Lizenz creative commons licence
Titel (primär) The Bacillus subtilis circadian clock coordinates intricate spatiotemporal organisation
Autor Dorling, J.; Sartor, F.; Ferrero-Bordera, B.; Godfrey, E.; Eelderink-Chen, Z.; Baker, E.; Banks, I.K.; Joshipura, A.; Xu, X.; Avellan, R.; Kovács, Á.; Dodd, A.N.; Merrow, M.
Quelle Nature Communications
Erscheinungsjahr 2026
Department MOLTOX
Band/Volume 17
Seite von art. 7709
Sprache englisch
Topic T9 Healthy Planet
Daten-/Softwarelinks https://doi.org/10.5281/zenodo.19821962
Supplements Supplement 1
Abstract Many organisms have circadian clocks that anticipate the risks and benefits of the predictable 24 h solar cycle. However, the potential functions of circadian clocks in non-photosynthetic bacteria are poorly understood. Here, we show that the Bacillus subtilis circadian clock regulates colony expansion, in concert with key developmental and differentiation pathways that are central to its life cycle. The B. subtilis clock coordinates the spatiotemporal organisation of gene expression within expanding colonies by timing various processes to specific phases (times of day) within distinct colony regions. Our results support the idea that circadian clock-regulation over space, time and colony development in B. subtilis is analogous to circadian regulation of some processes in multicellular eukaryotes such as plants and mammals.
Dorling, J., Sartor, F., Ferrero-Bordera, B., Godfrey, E., Eelderink-Chen, Z., Baker, E., Banks, I.K., Joshipura, A., Xu, X., Avellan, R., Kovács, Á., Dodd, A.N., Merrow, M. (2026):
The Bacillus subtilis circadian clock coordinates intricate spatiotemporal organisation
Nat. Commun. 17 , art. 7709
10.1038/s41467-026-74082-0