Alix Aldehoff

PhD Student Funktionelle Metabolomik Funktionelle Genomics

Kontakt

Adresse:
Gebäude 6.0
Permoserstr. 15
04318 Leipzig
Telefon: +49 341 235 1541
alix-sarah.aldehoff@ufz.de

Foto: Sebastian Wiedling/UFZ

ResearchGate

Forschungsschwerpunkte

Untersuchung der Effekte von Xenobiotika auf die Funktion und Differenzierung von Adipozyten mittels Metabolomik und Proteomik
Analyse des Status der post-translationalen Proteinmodifikationen und ihrer Rolle während der Adipozytendifferenzierung

Lebenslauf

Okt 2021 - heute	Doktorandin im SFB1052, Projekt Z3 Helmholtz-Zentrum für Umweltforschung, Leipzig Post-translational modifications in the context of adipocyte differentiation and their exposure to environmental contaminants
2018 - 2021	Master of Science in Biotechnologie Westfälische Wilhelms-Universität Münster Analysis of the impact of perfluoroalkyl substance exposure on a simplified human intestinal microbiota using proteomics and metabolomics
2015 - 2018	Bachelor of Science Biological Sciences Westfälische Wilhelms-Universität Münster Functional analysis of selected lysine residues on Rubisco activase activity in Arabidopsis thaliana

Publikationen

Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.

2025 (2)

Aldehoff, A.S., Türkowsky, D., Lohmann, P., Homsi, M.N., Rolle-Kampczyk, U., Ueberham, E., Lehmann, J., von Bergen, M., Jehmlich, N., Haange, S.-B. (2025):
Revealing novel protein interaction partners of glyphosate in Escherichia coli
Environ. Int. 195 , art. 109243 10.1016/j.envint.2024.109243
Krupka, S., Aldehoff, A.S., Goerdeler, C., Engelmann, B., Rolle-Kampczyk, U., Schubert, K., Klöting, N., von Bergen, M., Blüher, M. (2025):
Metabolic and molecular characterization, following dietary exposure to DINCH, reveals new implications for its role as a metabolism-disrupting chemical
Environ. Int. 196 , art. 109306 10.1016/j.envint.2025.109306

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2024 (10)

Aldehoff, A.S., Karkossa, I., Goerdeler, C., Krieg, L., Schor, J., Engelmann, B., Wabitsch, M., Landgraf, K., Hackermüller, J., Körner, A., Rolle-Kampczyk, U., Schubert, K., von Bergen, M. (2024):
Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis
iScience 27 (6), art. 109711 10.1016/j.isci.2024.109711
Fischer, F., Pierzchalski, A., Riesbeck, S., Aldehoff, A.S., Castañeda-Monsalve, V., Haange, S.-B., von Bergen, M., Rolle-Kampczyk, U.E., Jehmlich, N., Zenclussen, A.C., Herberth, G. (2024):
An in vitro model system for testing chemical effects on microbiome-immune interactions - examples with BPX and PFAS mixtures
Front. Immunol. 15 , art. 1298971 10.3389/fimmu.2024.1298971
Goerdeler, C., Engelmann, B., Aldehoff, A.S., Schaffert, A., Blüher, M., Heiker, J.T., Wabitsch, M., Schubert, K., Rolle-Kampczyk, U., von Bergen, M. (2024):
Metabolomics in human SGBS cells as new approach method for studying adipogenic effects: Analysis of the effects of DINCH and MINCH on central carbon metabolism
Environ. Res. 252 , art. 118847 10.1016/j.envres.2024.118847
Haange, S.-B., Riesbeck, S., Aldehoff, A.S., Engelmann, B., Jensen Pedersen, K., Castañeda-Monsalve, V., Rolle-Kampczyk, U., von Bergen, M., Jehmlich, N. (2024):
Chemical mixture effects on the simplified human intestinal microbiota: Assessing xenobiotics at environmentally realistic concentrations
J. Hazard. Mater. 474 , art. 134683 10.1016/j.jhazmat.2024.134683
Schubert, K., Aldehoff, A.S. (2024):
Phosphoproteome dynamics during differentiation of SGBS adipocytes
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD045770
Schubert, K., Aldehoff, A.S. (2024):
Phosphoproteome dynamics during differentiation of 3T3-L1 adipocytes
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD045778
Schubert, K., Aldehoff, A.S. (2024):
Acetylome dynamics during differentiation of SGBS adipocytes
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD045768
Schubert, K., Aldehoff, A.S. (2024):
Proteome dynamics during differentiation of SGBS adipocytes
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD045767
Schubert, K., Aldehoff, A.S. (2024):
Acetylome dynamics during differentiation of 3T3-L1 adipocytes
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD045776
Schubert, K., Aldehoff, A.S. (2024):
Proteome dynamics during differentiation of 3T3-L1 adipocytes
PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD045772

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2023 (1)

Aldehoff, A.S., Karkossa, I., Engelmann, B., Rolle-Kampczyk, U., von Bergen, M., Schubert, K. (2023):
Exploring the regulatory effects of lysine acetylation and phosphorylation in adipocyte differentiation and their exposure to emerging plastic additives
Toxicol. Lett. 384 (Suppl. 1), S133 - S133 10.1016/S0378-4274(23)00578-7

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Aktuelle Publikationen

2025 (8)

Aldehoff, A.S., Türkowsky, D., Lohmann, P., Homsi, M.N., Rolle-Kampczyk, U., Ueberham, E., Lehmann, J., von Bergen, M., Jehmlich, N., Haange, S.-B. (2025):
Revealing novel protein interaction partners of glyphosate in Escherichia coli
Environ. Int. 195 , art. 109243 10.1016/j.envint.2024.109243
Canzler, S., Schubert, K., Rolle-Kampczyk, U.E., Wang, Z., Schreiber, S., Seitz, H., Mockly, S., Kamp, H., Haake, V., Huisinga, M., von Bergen, M., Buesen, R., Hackermüller, J. (2025):
Evaluating the performance of multi-omics integration: a thyroid toxicity case study
Arch. Toxicol. 99 (1), 309 - 332 10.1007/s00204-024-03876-2
Castañeda-Monsalve, V., Haange, S.-B., Fröhlich, L.-F., Fu, Q., Rolle-Kampczyk, U., von Bergen, M., Jehmlich, N. (2025):
Food colorant brilliant blue causes persistent functional and structural changes in an in vitro simplified microbiota model system
ISME Commun. 5 (1), ycaf050 10.1093/ismeco/ycaf050
Gómez-Olarte, S., Röder, S., Rolle-Kampczyk, U., Sack, U., von Bergen, M., Borte, M., Zenclussen, A.C., Herberth, G. (2025):
Prenatal exposure to mixtures of phthalates and bisphenol A and eczema risk: findings in atopic and non-atopic children from the LiNA birth cohort
Environ. Res. , art. 121667 10.1016/j.envres.2025.121667
Krupka, S., Aldehoff, A.S., Goerdeler, C., Engelmann, B., Rolle-Kampczyk, U., Schubert, K., Klöting, N., von Bergen, M., Blüher, M. (2025):
Metabolic and molecular characterization, following dietary exposure to DINCH, reveals new implications for its role as a metabolism-disrupting chemical
Environ. Int. 196 , art. 109306 10.1016/j.envint.2025.109306
Reddy, L.R., Egerter, C., Jehmlich, N., Fiskal, A., Helmholz, L., Castronovo, S., Schweyen, P., Wulf, S.-E., Ternes, T., Wick, A., Meier, J. (2025):
New insights in the metabolic functions of freshwater sulfate reducing communities during steel corrosion by biophysicochemical, 16S rRNA gene sequence and metaproteomic analysis
Int. Biodeterior. Biodegrad. 198 , art. 105995 10.1016/j.ibiod.2024.105995
Schlößer, S., Ullrich, A.-L., Modares, N.F., Schmitz, M.A., Schöneich, J., Zhang, K., Richter, I., Robrahn, L., Schraven, S., Nagai, J.S., Haange, S.-B., Jennings, S.A.V., Clavel, T., Rolle-Kampczyk, U., Kiessling, F., Costa, I.G., Muncan, V., Repnik, U., von Bergen, M., Dupont, A., Hornef, M.W. (2025):
Salmonella infection accelerates postnatal maturation of the intestinal epithelium
Proc. Natl. Acad. Sci. U.S.A. 122 (1), e2403344122 10.1073/pnas.2403344122
Tanca, A., Schallert, K., Grenga, L., Peters, S.L., Abbondio, M., De Diego, L., Deledda, M.A., Haange, S.-B., Miotello, G., Sáenz, J.S., Wolf, M., Bastida, F., Devos, S., Hernandez-Raquet, G., Seifert, J., Wilmes, P., Van Den Bossche, T., Kunath, B.J., Heyer, R., Jehmlich, N., Benndorf, D., Hettich, R.L., Armengaud, J., Uzzau, S. (2025):
Critical Assessment of MetaProteome Investigation 2 (CAMPI-2): Multi-laboratory assessment of sample processing methods to stabilize fecal microbiome for functional analysis
bioRxiv 10.1101/2025.01.31.635836

Alix Aldehoff

PhD Student Funktionelle Metabolomik Funktionelle Genomics

Kontakt

Wissenschaftsnetzwerk

Forschungsschwerpunkte

Lebenslauf

Publikationen

Inhalt:

2025 (2)

2024 (10)

2023 (1)