Dr. Beatrice EngelmannPostdoc Funktionelle MetabolomikKontaktAdresse: Gebäude 6.0 Permoserstr. 15 04318 Leipzig Telefon: +49 341 6025 1099 |
Foto: Sebastian Wiedling/UFZ
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Forschungsschwerpunkte
- Methodenetablierung für die gezielte Quantifizierung von Metaboliten
- Untargeted metabolomics zum Metabolit-Screening für vergleichende Analysen
Lebenslauf
| Seit Nov 2018 | PostDoc in der Arbeitsgruppe Funktionelle Metabolomik |
| Aug 2017 - Aug 2018 |
PostDoc in der Abteilung für Funktionelle Genomforschung, Universitätsmedizin Greifswald |
| 2013 - 2017 |
Dissertation in der Abteilung für Funktionelle Genomforschung, Interfakultäres Institut für Genetik und Funktionelle Genomforschung, Universitätsmedizin Greifswald |
| 2008 - 2013 |
Diplom Biochemie Universität Greifswald |
Publikationen
Inhalt:
Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.
2025 (1)
- Krupka, S., Aldehoff, A.S., Goerdeler, C., Engelmann, B., Rolle-Kampczyk, U., Schubert, K., Klöting, N., von Bergen, M., Blüher, M. (2025):
Metabolic and molecular characterization, following dietary exposure to DINCH, reveals new implications for its role as a metabolism-disrupting chemical
Environ. Int. 196 , art. 109306 10.1016/j.envint.2025.109306
2024 (10)
- Aldehoff, A.S., Karkossa, I., Goerdeler, C., Krieg, L., Schor, J., Engelmann, B., Wabitsch, M., Landgraf, K., Hackermüller, J., Körner, A., Rolle-Kampczyk, U., Schubert, K., von Bergen, M. (2024):
Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis
iScience 27 (6), art. 109711 10.1016/j.isci.2024.109711 - Engelmann, B. (2024):
Summary of project PR002051
UCSD Metabolomics Workbench 10.21228/M8H521 - Goerdeler, C., Engelmann, B., Aldehoff, A.S., Schaffert, A., Blüher, M., Heiker, J.T., Wabitsch, M., Schubert, K., Rolle-Kampczyk, U., von Bergen, M. (2024):
Metabolomics in human SGBS cells as new approach method for studying adipogenic effects: Analysis of the effects of DINCH and MINCH on central carbon metabolism
Environ. Res. 252 , art. 118847 10.1016/j.envres.2024.118847 - Haange, S.-B., Riesbeck, S., Aldehoff, A.S., Engelmann, B., Jensen Pedersen, K., Castañeda-Monsalve, V., Rolle-Kampczyk, U., von Bergen, M., Jehmlich, N. (2024):
Chemical mixture effects on the simplified human intestinal microbiota: Assessing xenobiotics at environmentally realistic concentrations
J. Hazard. Mater. 474 , art. 134683 10.1016/j.jhazmat.2024.134683 - Huillet, M., Lasserre, F., Gratacap, M.-P., Engelmann, B., Bruse, J., Polizzi, A., Fougeray, T., Martin, C.M.P., Rives, C., Fougerat, A., Naylies, C., Lippi, Y., Garcia, G., Rousseau-Bacquie, E., Canlet, C., Debrauwer, L., Rolle-Kampczyk, U., von Bergen, M., Payrastre, B., Boutet-Robinet, E., Gamet-Payrastre, L., Guillou, H., Loiseau, N., Ellero-Simatos, S. (2024):
Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism
JHEP Rep. 6 (1), art. 100930 10.1016/j.jhepr.2023.100930 - Jax, M., Weßendorf, A., Lichter, J., Stief, L., Lobes, N., Egele, K., Rolle-Kampczyk, U., Engelmann, B., von Bergen, M., Bock, U., Blömeke, B. (2024):
Response of innate immune cells and alveolar type 1 cell line to 4,4'-methylenediphenyl diisocyanate
Naunyn-Schmiedebergs Arch. Pharmacol. 397 (Suppl. 1), S73 - P231 10.1007/s00210-024-02974-3 - Krause, J.L., Engelmann, B., Lallinger, D.J.D., Rolle-Kampczyk, U., von Bergen, M., Chang, H.-D. (2024):
Multi-omics analysis unravels the impact of stool sample logistics on metabolites and microbial composition
Microorganisms 12 (10), art. 1998 10.3390/microorganisms12101998 - Krause, J.L., Engelmann, B., Schaepe, S.S., Rolle-Kampczyk, U., Jehmlich, N., Chang, H.-D., Slanina, U., Hoffmann, M., Lehmann, J., Zenclussen, A.C., Herberth, G., von Bergen, M., Haange, S.-B. (2024):
DSS treatment does not affect murine colonic microbiota in absence of the host
Gut Microbes 16 (1), art. 2297831 10.1080/19490976.2023.2297831 - Radushev, V., Karkossa, I., Berg, J., von Bergen, M., Engelmann, B., Rolle-Kampczyk, U.E., Blüher, M., Wagner, U., Schubert, K., Rossol, M. (2024):
Dysregulated cytokine and oxidative response in hyper-glycolytic monocytes in obesity
Front. Immunol. 15 , art. 1416543 10.3389/fimmu.2024.1416543 - Viehof, A., Haange, S.-B., Streidl, T., Schubert, K., Engelmann, B., Haller, D., Rolle-Kampczyk, U., von Bergen, M., Clavel, T. (2024):
The human intestinal bacterium Eggerthella lenta influences gut metabolomes in gnotobiotic mice
Microbiome Research Reports 3 , art. 14 10.20517/mrr.2023.65
2023 (7)
- Aldehoff, A.S., Karkossa, I., Engelmann, B., Rolle-Kampczyk, U., von Bergen, M., Schubert, K. (2023):
Exploring the regulatory effects of lysine acetylation and phosphorylation in adipocyte differentiation and their exposure to emerging plastic additives
Toxicol. Lett. 384 (Suppl. 1), S133 - S133 10.1016/S0378-4274(23)00578-7 - Engelmann, B. (2023):
Untangling the dynamics of lysine acetylation and phosphorylation in adipogenesis in the established human and mouse adipocyte cell lines SGBS and 3T3L1
UCSD Metabolomics Workbench 10.21228/M8GX42 - Hoffmann, A., Meir, A.Y., Hagemann, T., Czechowski, P., Müller, L., Engelmann, B., Haange, S.-B., Rolle-Kampczyk, U., Tsaban, G., Zelicha, H., Rinott, E., Kaplan, A., Shelef, I., Stumvoll, M., Blüher, M., Liang, L., Ceglarek, U., Isermann, B., von Bergen, M., Kovacs, P., Keller, M., Shai, I. (2023):
A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: the DIRECT PLUS randomized controlled trial
Metab.-Clin. Exp. 145 , art. 155594 10.1016/j.metabol.2023.155594 - Meir, A.Y., Keller, M., Hoffmann, A., Rinott, E., Tsaban, G., Kaplan, A., Zelicha, H., Hagemann, T., Ceglarek, U., Isermann, B., Shelef, I., Blüher, M., Stumvoll, M., Li, J., Haange, S.-B., Engelmann, B., Rolle-Kampczyk, U., von Bergen, M., Hu, F.B., Stampfer, M.J., Kovacs, P., Liang, L., Shai, I. (2023):
The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial
BMC Med. 21 , art. 364 10.1186/s12916-023-03067-3 - O’Rourke, K., Engelmann, B., Altenburger, R., Rolle-Kampczyk, U., Grintzalis, K. (2023):
Molecular responses of daphnids to chronic exposures to pharmaceuticals
Int. J. Mol. Sci. 24 (4), art. 4100 10.3390/ijms24044100 - Panagiotidis, K., Engelmann, B., Krauss, M., Rolle-Kampczyk, U.E., Altenburger, R., Rochfort, K.D., Grintzalis, K. (2023):
The impact of amine and carboxyl functionalised microplastics on the physiology of daphnids
J. Hazard. Mater. 458 , art. 132023 10.1016/j.jhazmat.2023.132023 - Ramos-Nascimento, A., Grenga, L., Haange, S.-B., Himmelmann, A., Arndt, F.S., Ly, Y.-T., Miotello, G., Pible, O., Jehmlich, N., Engelmann, B., von Bergen, M., Mulder, E., Frings-Meuthen, P., Hellweg, C.E., Jordan, J., Rolle-Kampczyk, U., Armengaud, J., Moeller, R. (2023):
Human gut microbiome and metabolite dynamics under simulated microgravity
Gut Microbes 15 (2), art. 2259033 10.1080/19490976.2023.2259033
2022 (4)
- Brede, M., Haange, S.-B., Riede, S., Engelmann, B., Jehmlich, N., Rolle-Kampczyk, U.E., Rohn, K., Von Soosten, D., von Bergen, M., Breves, G. (2022):
Effects of different formulations of glyphosate on rumen microbial metabolism and microbial community composition in the Rumen Simulation Technique system
Front. Microbiol. 13 , art. 873101 10.3389/fmicb.2022.873101 - Jensen Pedersen, K., Haange, S.-B., Žížalová, K., Viehof, A., Clavel, T., Leniček, M., Engelmann, B., Wick, L.Y., Schaap, F.G., Jehmlich, N., Rolle-Kampczyk, U., von Bergen, M. (2022):
Eggerthella lenta DSM 2243 alleviates bile acid stress response in Clostridium ramosum and Anaerostipes caccae by transformation of bile acids
Microorganisms 10 (10), art. 2025 10.3390/microorganisms10102025 - Krause, J.L., Engelmann, B., Nunes da Rocha, U., Pierzchalski, A., Chang, H.D., Zenclussen, A.C., von Bergen, M., Rolle-Kampczyk, U., Herberth, G. (2022):
MAIT cell activation is reduced by direct and microbiota-mediated exposure to bisphenols
Environ. Int. 158 , art. 106985 10.1016/j.envint.2021.106985 - Zelicha, H., Kloting, N., Kaplan, A., Meir, A.Y., Rinott, E., Tsaban, G., Chassidim, Y., Bluher, M., Ceglarek, U., Isermann, B., Stumvoll, M., Quayson, R.N., von Bergen, M., Engelmann, B., Rolle-Kampczyk, U., Haange, S.-B., Tuohy, K.M., Diotallevi, C., Shelef, I., Hu, F.B., Stampfer, M.J., Shai, I. (2022):
The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial
BMC Med. 20 , art. 327 10.1186/s12916-022-02525-8
2021 (4)
- Medawar, E., Haange, S.-B., Rolle-Kampczyk, U., Engelmann, B., Dietrich, A., Thieleking, R., Wiegank, C., Fries, C., Horstmann, A., Villringer, A., von Bergen, M., Fenske, W., Witte, A.V. (2021):
Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior
Transl. Psychiatr. 11 , art. 500 10.1038/s41398-021-01620-3 - Schubert, K., Karkossa, I., Schor, J., Engelmann, B., Steinheuer, L.M., Bruns, T., Rolle-Kampczyk, U., Hackermüller, J., von Bergen, M. (2021):
A multi-omics analysis of mucosal-associated-invariant T cells reveals key drivers of distinct modes of activation
Front. Immunol. 12 , art. 616967 10.3389/fimmu.2021.616967 - Smith, L., Martin, C., Lasserre, F., Engelmann, B., Klément, W., Fougerat, A., Polizzi, A., Canlet, C., Rolle-Kampczyk, U., von Bergen, M., Lippi, Y., Guillou, H., Loiseau, N., Payastre, L., Ellero-Simatos, S. (2021):
Impact d’une exposition alimentaire chronique au glyphosate à des doses de référence sur le microbiote intestinal et le métabolisme énergétique chez la souris
Nutr. Clin. Metab. 35 (1), 74 - 74 10.1016/j.nupar.2021.01.110 - Venkat, K., Hoyos, M., Haycocks, J.R.J., Cassidy, L., Engelmann, B., Rolle-Kampczyk, U., von Bergen, M., Tholey, A., Grainger, D.C., Papenfort, K. (2021):
A dual-function RNA balances carbon uptake and central metabolism in Vibrio cholerae
Embo J. 40 (24), e108542 10.15252/embj.2021108542
2020 (3)
- Fritz-Wallace, K., Engelmann, B., Krause, J.L., Schäpe, S.S., Pöppe, J., Herberth, G., Rösler, U., Jehmlich, N., von Bergen, M., Rolle-Kampczyk, U. (2020):
Quantification of glyphosate and AMPA from microbiome reactor fluids
Rapid Commun. Mass Spectrom. 34 (7), e8668 10.1002/rcm.8668 - Krause, J.L., Haange, S.-B., Schäpe, S.S., Engelmann, B., Rolle-Kampczyk, U., Fritz-Wallace, K., Wang, Z., Jehmlich, N., Türkowsky, D., Schubert, K., Pöppe, J., Bote, K., Rösler, U., Herberth, G., von Bergen, M. (2020):
The glyphosate formulation Roundup® LB plus influences the global metabolome of pig gut microbiota in vitro
Sci. Total Environ. 745 , art. 140932 10.1016/j.scitotenv.2020.140932 - Krause, J.L., Schaepe, S.S., Fritz-Wallace, K., Engelmann, B., Rolle-Kampczyk, U., Kleinsteuber, S., Schattenberg, F., Liu, Z., Müller, S., Jehmlich, N., von Bergen, M., Herberth, G. (2020):
Following the community development of SIHUMIx – a new intestinal in vitro model for bioreactor use
Gut Microbes 11 (4), 1116 - 1129 10.1080/19490976.2019.1702431
2019 (1)
- Schäpe, S.S., Krause, J.L., Engelmann, B., Fritz-Wallace, K., Schattenberg, F., Liu, Z., Müller, S., Jehmlich, N., Rolle-Kampczyk, U., Herberth, G., von Bergen, M. (2019):
The simplified human intestinal microbiota (SIHUMIx) shows high structural and functional resistance against changing transit times in in vitro bioreactors
Microorganisms 7 (12), art. 641 10.3390/microorganisms7120641
Kornej J, Büttner P, Hammer E, Engelmann B, Dinov B, Sommer P, Husser D, Hindricks G, Völker U, Bollmann A.
Circulating proteomic patterns in AF related left atrial remodeling indicate involvement of coagulation and complement cascade.
PLoS One. 2018 Nov 29;13(11):e0198461. doi: 10.1371/journal.pone.0198461
Pietzner M, Engelmann B, Kacprowski T, Golchert J, Dirk AL, Hammer E, Iwen KA, Nauck M, Wallaschofski H, Führer D, Münte TF, Friedrich N, Völker U, Homuth G, Brabant G.
Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model.
BMC Med. 2017 Jan 9;15(1):6. doi: 10.1186/s12916-016-0770-8
Engelmann B, Bischof J, Dirk AL, Friedrich N, Hammer E, Thiele T, Führer D, Homuth G, Brabant G, Völker U.
Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study.
Eur Thyroid J. 2015 Sep;4(Suppl 1):119-24. doi: 10.1159/000381769
Sandetskaya N, Engelmann B, Brandenburg K, Kuhlmeier D.
Application of immobilized synthetic anti-lipopolysaccharide peptides for the isolation and detection of bacteria.
Eur J Clin Microbiol Infect Dis. 2015 Aug;34(8):1639-45. doi: 10.1007/s10096-015-2399-5