Dr. Kristin Schubert
Kontakt / Adressen
Dr. rer. nat. Kristin Schubert
Arbeitsgruppenleitung 'Functional Genomics'
Department für Molekulare Systembiologie
Helmholtz Zentrum für Umweltforschung - UFZ
Permoserstraße 15 | 04318 Leipzig
Phone: +49 341 235 1819
kristin.schubert@ufz.de
kristin.schubert@kennedy.ox.ac.uk
Forschungsschwerpunkte
- Systembiologische Analyse der Funktion von MAIT-Zellen und Makrophagen
- Mode of Action von Schadstoffen
- Immunoproteomics
- Immunometabolismus
Lebenslauf
| seit 2017 |
Arbeitsgruppenleitung 'Functional Genomics' Department für Molekulare Systembiologie Helmholtz Zentrum für Umweltforschung - UFZ |
| seit 2016 |
Associated Postdoctoral Researcher Kennedy Institute of Rheumatology, University of Oxford, UK |
| 2014 - 2016 |
Postdoctoral Researcher Kennedy Institute of Rheumatology, University of Oxford, UK |
| 2010 - 2013 |
PhD Student Experimentelle Rheumatologie, Universität Leipzig |
| 2003 - 2009 |
Biologie Studium (Diplom) Martin-Luther-Universität Halle-Wittenberg |
Publikationen
Inhalt:
2020 (5)2019 (7)
2018 (2)
2017 (1)
Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.
2020 (5)
- Bannuscher, A., Karkossa, I., Buhs, S., Nollau, P., Kettler, K., Balas, M., Dinischiotu, A., Hellack, B., Wiemann, M., Luch, A., von Bergen, M., Haase, A., Schubert, K., (2020):
A multi-omics approach reveals mechanisms of nanomaterial toxicity and structure–activity relationships in alveolar macrophages
Nanotoxicology 14 (2), 181 - 195
Volltext (DOI) - Canzler, S., Schor, J., Busch, W., Schubert, K., Rolle-Kampczyk, U.E., Seitz, H., Kamp, H., von Bergen, M., Buesen, R., Hackermüller, J., (2020):
Prospects and challenges of multi‑omics data integration in toxicology
Arch. Toxicol. 94 (2), 371 - 388
Volltext (DOI) - Kalkhof, S., Krieg, L., Büttner, P., Wabitsch, M., Küntzel, C., Friebe, D., Landgraf, K., Hanschkow, M., Schubert, K., Kiess, W., Krohn, K., Blüher, M., von Bergen, M., Körner, A., (2020):
In depth quantitative proteomic and transcriptomic characterization of human adipocyte differentiation using the SGBS cell line
Proteomics 20 (15-16), art. 1900405
Volltext (DOI) - Krause, J.L., Haange, S.-B., Schäpe, S.S., Engelmann, B., Rolle-Kampczyk, U., Fritz-Wallace, K., Wang, Z., Jehmlich, N., Türkowsky, D., Schubert, K., Pöppe, J., Bote, K., Rösler, U., Herberth, G., von Bergen, M., (2020):
The glyphosate formulation Roundup® LB plus influences the global metabolome of pig gut microbiota in vitro
Sci. Total Environ. 745 , art. 140932
Volltext (DOI) - Krieg, L., Schaffert, A., Kern, M., Landgraf, K., Wabitsch, M., Beck-Sickinger, A.G., Koerner, A., Blüher, M., von Bergen, M., Schubert, K., (2020):
An MRM-based multiplexed quantification assay for human adipokines and apolipoproteins
Molecules 25 (4), art. 775
Volltext (DOI)
2019 (7)
- Großkopf, H., Schubert, K., von Bergen, M., (2019):
AhR-dependent non-genomic signaling in macrophages - A multi-PTM-omics and proteomics study
Eur. J. Immunol. 49 (Suppl. 1), 137
Volltext (DOI) - Karkossa, I., Bannuscher, A., Hellack, B., Bahl, A., Buhs, S., Nollau, P., Luch, A., Schubert, K., von Bergen, M., Haase, A., (2019):
An in-depth multi-omics analysis in RLE-6TN rat alveolar epithelial cells allows for nanomaterial categorization
Part. Fibre Toxicol. 16 (1), art. 38
Volltext (DOI) - Kratochvil, I., Bannuscher, A., Hellack, B., von Bergen, M., Haase, A., Schubert, K., (2019):
Nanomaterials affect oxidative phosphorylation and phagocytosis in alveolar macrophages
Eur. J. Immunol. 49 (Suppl. 1), 232
Volltext (DOI) - Schmidt, J.R., Geurtzen, K., von Bergen, M., Schubert, K., Knopf, F., (2019):
Glucocorticoid treatment leads to aberrant ion and macromolecular transport in regenerating zebrafish fins
Front. Endocrinol. 10 , art. 674
Volltext (DOI) - Schmidt, J.R., Vogel, S., Moeller, S., Kalkhof, S., Schubert, K., von Bergen, M., Hempel, U., (2019):
Sulfated hyaluronic acid and dexamethasone possess a synergistic potential in the differentiation of osteoblasts from human bone marrow stromal cells
J. Cell. Biochem. 120 (5), 8706 - 8722
Volltext (DOI) - Schubert, K., Collins, L.E., Green, P., Nagase, H., Troeberg, L., (2019):
LRP1 controls TNF release via the TIMP-3/ADAM17 axis in endotoxin-activated macrophages
J. Immunol. 202 (4), 1501 - 1509
Volltext (DOI) - Schubert, K., Schor, J., Kratochvil, I., Hackermüller, J., von Bergen, M., (2019):
Multi-omics profiling of MAIT cells reveals specific patterns of antigen-dependent and -independent activation
Eur. J. Immunol. 49 (Suppl. 1), 141
Volltext (DOI)
2018 (2)
- Firacative, C., Gressler, A.E., Schubert, K., Schulze, B., Müller, U., Brombacher, F., von Bergen, M., Alber, G., (2018):
Identification of T helper (Th)1- and Th2-associated antigens of Cryptococcus neoformans in a murine model of pulmonary infection
Sci. Rep. 8 , art. 2681
Volltext (DOI) - Schmidt, J.R., Rücker-Braun, E., Heidrich, K., von Bonin, M., Stölzel, F., Thiede, C., Middeke, J.M., Ehninger, G., Bornhäuser, M., Schetelig, J., Schubert, K., von Bergen, M., Heidenreich, F., (2018):
Pilot study on mass spectrometry–based analysis of the proteome of CD34+CD123+ progenitor cells for the identification of potential targets for immunotherapy in acute myeloid leukemia
Proteomes 6 (1), art. 11
Volltext (DOI)
2017 (1)
- Schubert, K., Olde Damink, S.W.M., von Bergen, M., Schaap, F.G., (2017):
Interactions between bile salts, gut microbiota, and hepatic innate immunity
Immunol. Rev. 279 (1), 23 - 35
Volltext (DOI)
Schmidt, J. R., E. Rucker-Braun, K. Heidrich, M. von Bonin, F. Stolzel, C. Thiede, J. M. Middeke, et al. "Pilot Study on Mass Spectrometry-Based Analysis of the Proteome of Cd34(+)Cd123(+) Progenitor Cells for the Identification of Potential Targets for Immunotherapy in Acute Myeloid Leukemia." Proteomes 6, no. 1 (Feb 12 2018).
Firacative, C., A. E. Gressler, K. Schubert, B. Schulze, U. Muller, F. Brombacher, M. von Bergen, and G. Alber. "Identification of T Helper (Th)1- and Th2-Associated Antigens of Cryptococcus Neoformans in a Murine Model of Pulmonary Infection." Sci Rep 8, no. 1 (Feb 8 2018): 2681.
Schubert, K., S. W. M. Olde Damink, M. von Bergen, and F. G. Schaap. "Interactions between Bile Salts, Gut Microbiota, and Hepatic Innate Immunity." Immunol Rev 279, no. 1 (Sep 2017): 23-35.
Rothe, K., D. Quandt, K. Schubert, M. Rossol, M. Klingner, S. Jasinski-Bergner, R. Scholz, et al. "Latent Cytomegalovirus Infection in Rheumatoid Arthritis and Increased Frequencies of Cytolytic Lir-1+Cd8+ T Cells." Arthritis Rheumatol 68, no. 2 (Feb 2016): 337-46.
Schubert, K., U. Meusch, R. Scholz, M. Rossol, and U. Wagner. "To Which Lineage Do Tumor Necrosis Factor Receptor Type I-Positive Proinflammatory Cells Belong? " Arthritis Rheumatol 66, no. 7 (Jul 2014): 1961-2.
Rossol, M.*, K. Schubert*, U. Meusch, A. Schulz, B. Biedermann, J. Grosche, M. Pierer, et al. "Tumor Necrosis Factor Receptor Type I Expression of Cd4+ T Cells in Rheumatoid Arthritis Enables Them to Follow Tumor Necrosis Factor Gradients into the Rheumatoid Synovium." Arthritis Rheum 65, no. 6 (Jun 2013): 1468-76. *shared authorship
Annibal, A., K. Schubert, U. Wagner, R. Hoffmann, J. Schiller, and M. Fedorova. "New Covalent Modifications of Phosphatidylethanolamine by Alkanals: Mass Spectrometry Based Structural Characterization and Biological Effects." J Mass Spectrom 49, no. 7 (Jul 2014): 557-69.
Rossol, M., M. Pierer, N. Raulien, D. Quandt, U. Meusch, K. Rothe, K. Schubert, et al. "Extracellular Ca2+ Is a Danger Signal Activating the Nlrp3 Inflammasome through G Protein-Coupled Calcium Sensing Receptors." Nat Commun 3 (2012): 1329.