Dr. Kristin Schubert

Kontakt / Adressen


Dr. rer. nat. Kristin Schubert

Arbeitsgruppenleitung 'Functional Genomics'

Department für Molekulare Systembiologie
Helmholtz Zentrum für Umweltforschung - UFZ
Permoserstraße 15 | 04318 Leipzig

Phone: +49 341 235 1819
kristin.schubert@ufz.de
kristin.schubert@kennedy.ox.ac.uk


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Forschungsschwerpunkte


  • Systembiologische Analyse der Funktion von MAIT-Zellen und Makrophagen
  • Mode of Action von Schadstoffen
  • Immunoproteomics
  • Immunometabolismus


Lebenslauf


            

seit 2017 Arbeitsgruppenleitung 'Functional Genomics'
Department für Molekulare Systembiologie
Helmholtz Zentrum für Umweltforschung - UFZ
seit 2016 Associated Postdoctoral Researcher
Kennedy Institute of Rheumatology, University of Oxford, UK
2014 - 2016 Postdoctoral Researcher
Kennedy Institute of Rheumatology, University of Oxford, UK
2010 - 2013 PhD Student
Experimentelle Rheumatologie, Universität Leipzig
2003 - 2009 Biologie Studium (Diplom)
Martin-Luther-Universität Halle-Wittenberg

Publikationen


Inhalt:

2019 (2)
2018 (2)
2017 (1)

Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.

2019 (2)

  • Schmidt, J.R., Vogel, S., Moeller, S., Kalkhof, S., Schubert, K., von Bergen, M., Hempel, U., (2019):
    Sulfated hyaluronic acid and dexamethasone possess a synergistic potential in the differentiation of osteoblasts from human bone marrow stromal cells
    J. Cell. Biochem. 120 (5), 8706 - 8722
    Volltext (URL)
  • Schubert, K., Collins, L.E., Green, P., Nagase, H., Troeberg, L., (2019):
    LRP1 controls TNF release via the TIMP-3/ADAM17 axis in endotoxin-activated macrophages
    J. Immunol. 202 (4), 1501 - 1509
    Volltext (URL)
zum Inhalt

2018 (2)

  • Firacative, C., Gressler, A.E., Schubert, K., Schulze, B., Müller, U., Brombacher, F., von Bergen, M., Alber, G., (2018):
    Identification of T helper (Th)1- and Th2-associated antigens of Cryptococcus neoformans in a murine model of pulmonary infection
    Sci. Rep. 8 , art. 2681
    Volltext (URL)
  • Schmidt, J.R., Rücker-Braun, E., Heidrich, K., von Bonin, M., Stölzel, F., Thiede, C., Middeke, J.M., Ehninger, G., Bornhäuser, M., Schetelig, J., Schubert, K., von Bergen, M., Heidenreich, F., (2018):
    Pilot study on mass spectrometry–based analysis of the proteome of CD34+CD123+ progenitor cells for the identification of potential targets for immunotherapy in acute myeloid leukemia
    Proteomes 6 (1), art. 11
    Volltext (URL)
zum Inhalt

2017 (1)

  • Schubert, K., Olde Damink, S.W.M., von Bergen, M., Schaap, F.G., (2017):
    Interactions between bile salts, gut microbiota, and hepatic innate immunity
    Immunol. Rev. 279 (1), 23 - 35
    Volltext (URL)
zum Inhalt

Schmidt, J. R., E. Rucker-Braun, K. Heidrich, M. von Bonin, F. Stolzel, C. Thiede, J. M. Middeke, et al. "Pilot Study on Mass Spectrometry-Based Analysis of the Proteome of Cd34(+)Cd123(+) Progenitor Cells for the Identification of Potential Targets for Immunotherapy in Acute Myeloid Leukemia." Proteomes 6, no. 1 (Feb 12 2018).

Firacative, C., A. E. Gressler, K. Schubert, B. Schulze, U. Muller, F. Brombacher, M. von Bergen, and G. Alber. "Identification of T Helper (Th)1- and Th2-Associated Antigens of Cryptococcus Neoformans in a Murine Model of Pulmonary Infection." Sci Rep 8, no. 1 (Feb 8 2018): 2681.

Schubert, K., S. W. M. Olde Damink, M. von Bergen, and F. G. Schaap. "Interactions between Bile Salts, Gut Microbiota, and Hepatic Innate Immunity." Immunol Rev 279, no. 1 (Sep 2017): 23-35.

Rothe, K., D. Quandt, K. Schubert, M. Rossol, M. Klingner, S. Jasinski-Bergner, R. Scholz, et al. "Latent Cytomegalovirus Infection in Rheumatoid Arthritis and Increased Frequencies of Cytolytic Lir-1+Cd8+ T Cells." Arthritis Rheumatol 68, no. 2 (Feb 2016): 337-46.

Schubert, K., U. Meusch, R. Scholz, M. Rossol, and U. Wagner. "To Which Lineage Do Tumor Necrosis Factor Receptor Type I-Positive Proinflammatory Cells Belong? " Arthritis Rheumatol 66, no. 7 (Jul 2014): 1961-2.

Rossol, M.*, K. Schubert*, U. Meusch, A. Schulz, B. Biedermann, J. Grosche, M. Pierer, et al. "Tumor Necrosis Factor Receptor Type I Expression of Cd4+ T Cells in Rheumatoid Arthritis Enables Them to Follow Tumor Necrosis Factor Gradients into the Rheumatoid Synovium." Arthritis Rheum 65, no. 6 (Jun 2013): 1468-76. *shared authorship

Annibal, A., K. Schubert, U. Wagner, R. Hoffmann, J. Schiller, and M. Fedorova. "New Covalent Modifications of Phosphatidylethanolamine by Alkanals: Mass Spectrometry Based Structural Characterization and Biological Effects." J Mass Spectrom 49, no. 7 (Jul 2014): 557-69.

Rossol, M., M. Pierer, N. Raulien, D. Quandt, U. Meusch, K. Rothe, K. Schubert,  et al. "Extracellular Ca2+ Is a Danger Signal Activating the Nlrp3 Inflammasome through G Protein-Coupled Calcium Sensing Receptors." Nat Commun 3 (2012): 1329.