Cell culture models

Translation studies for substances safety assessment in pregnant women are not possible due to the potential health risk for the mother and the baby. In that order, we are establishing 3D (organoid and spheroid) cell culture methods and complex co-culturing systems to resemble the physiological and barrier properties of the placenta. Moreover, within our cell culture platform we have access to several immortalized placental cell lines and primary trophoblast and fibroblast cells that will help us to resemble the placental compartment in a controlled and reliable system.