Scientific Themes

Perinatal exposure of chemicals having pregnancy and birth effects

Coordinators: Prof. Ana Zenclussen and PD Dr. Anne Schumacher

Prof. Ana Zenclussen

PD Dr. Anne Schumacher

More information about this theme

Environmental factor-driven immune disbalances during pregnancy

Coordinator: PD Dr. Anne Schumacher

PD Dr. Anne Schumacher

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Maternal exposure and offspring health

Coordinator: PD Dr. Tobias Polte

PD Dr. Tobias Polte

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Lifestyle/Chemicals - Microbiome and Immunomodulation

Coordinator: Dr. Gunda Herberth

Dr. Gunda Herberth

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Environmental pollutant effect on placenta morphology and physiology

Coordinator: Dr. Violeta Stojanovska

Dr. Violeta Stojanovska

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Effects of environmental chemicals on the physiology of the vascular tissue

Coordinator: Dr. Nicole Meyer

Dr. Nicole Meyer

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Department News

We’re on Twitter!

Since recently you can follow us on the platform. There you will find interesting information about our working group, but also everything about our research activities and publications.

@UFZ_Immu

Congratulations to our medical doctoral students Elisabeth and Lukas for their successful application for PhD scholarships provided by the Medical Faculty, University of Leipzig!

The 25th Interdisziplinäre Kinderimmunologische Arbeitstreffen (KIAT) took place on November 11th in Leipzig. Prof. Ana Zenclussen and Dr. Gunda Herberth gave talks about immunology during pregnancy, the role of T cells and current results from cohort studies.

f.l.t.r.: Prof. Dr. Ulrich Sack, Dr. Gunda Herberth, Prof. Ana C. Zenclussen, Prof. Dr. Michael Borte
Photo: privat

We welcome our new project coordinator Susann Hähnel and the new medical doctoral students Elisabeth, Jonas and Lukas in our team!

Congratulations to our colleague Dr. Violeta Stojanovska for being the 3rd winner of the Participants Choice Awards at the Helmholtz Imaging Conference 2022!

https://helmholtz-imaging.de/

The first joint workshop with our Argentinian cooperation partners took place on 11 and 12 July. The participants were able to discuss the progress of the DFG project "Influence of endocrine disruptors on reproductive processes mediated by immune cells of the innate immune system", methods and to-dos. There was also space to plan further joint collaborations. We thank all participants for the exciting and productive exchange!

Back: Tobias Kretschmer, Anne Schumacher, Horacio Rodriguez, Ana Zenclussen, Nicole Meyer, Maria Zenclussen, Florence Fischer
Front: Violeta Stojanovska, Ambra Maddalon, Ningjuan Zhang, Federica Romanelli
Photo: Ana Zenclussen/UFZ

Congratulations to our colleague Dr. Violeta Stojanovska for being the 1st prize European Organoid Research Grant winner!

@biotechne

To what extent do older siblings influence the healthy development of children? Answers from our LiNA study can be found in our latest press release.

We congratulate Prof. Ana Zenclussen on her appointment as a member of the BfR Commission on Contaminants in the Food Chain for the session period 2022 to 2025 and wish her every success!

We may present: the Helmholtz portrait of Prof. Ana Zenclussen.

Latest publications

2023

Index:

2023 (17)

You could use our publication index for further requests.

2023 (17)

Bauer, M. (2023):
Editorial: Interplay between toxicants, natural toxins, and the immune system in animal models
Front. Immunol. 14 , art. 1186300
full text (doi)
Bauer, M., Raab, J., Fink, B. (2023):
Appearance of ghost bands in gel electrophoresis depending on agarose concentration
Electrophoresis
full text (doi)
Fischer, F., Ermer, M.R., Howanski, J., Zenclussen, A.C., Schumacher, A. (2023):
Bisphenol A and benzophenone-3, two ubiquitous endocrine disruptors, may interfere with tolerance pathways by disturbing the T cell equilibrium
Am. J. Reprod. Immunol. 89 (S1), 83 - 83
full text (doi)
Hofsink, N., Dijkstra, D.J., Stojanovska, V., Scherjon, S.A., Plösch, T. (2023):
Preeclampsia-induced alterations in brain and liver gene expression and DNA methylation patterns in fetal mice
J. Dev. Orig. Health Dis. 14 (1), 146 - 151
full text (doi)
Kilanowski, A., Thiering, E., Wang, G., Kumar, A., Kress, S., Flexeder, C., Bauer, C.-P., Berdel, D., von Berg, A., Bergström, A., Gappa, M., Heinrich, J., Herberth, G., Koletzko, S., Kull, I., Melen, E., Schikowski, T., Peters, A., Standl, M. (2023):
Allergic disease trajectories up to adolescence: Characteristics, early-life, and genetic determinants
Allergy 78 (3), 836 - 850
full text (doi)
Kotsakis Ruehlmann, A., Sammallahti, S., Cortés Hidalgo, A.P., Bakulski, K.M., Binder, E.B., Campbell, M.L., Caramaschi, D., Cecil, C., Colicino, E., Cruceanu, C., Czamara, D., Dieckmann, L., Dou, J., Felix, J.F., Frank, J., Håberg, S.E., Herberth, G., Hoang, T.T., Houtepen, L.C., Hüls, A., Koen, N., London, S.J., Magnus, M.C., Mancano, G., Mulder, R.H., Page, C.M., Räikkönen, K., Röder, S., Schmidt, R.J., Send, T.S., Sharp, G., Stein, D.J., Streit, F., Tuhkanen, J., Witt, S.H., Zar, H.J., Zenclussen, A.C., Zhang, Y., Zillich, L., Wright, R., Lahti, J., Brunst, K.J. (2023):
Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation
Mol. Psychiatr.
full text (doi)
Krause, J.L., Pierzchalski, A., Chang, H.D., Zenclussen, A.C., Bauer, M., Herberth, G. (2023):
Bisphenols, but not phthalate esters, modulate gene expression in activated human MAIT cells in vitro
Toxicol. Rep. 10 , 348 - 356
full text (doi)
Kretschmer, T., Fischer, F., Seifert, P., Schumacher, A., Kass, L., Rodríguez, H.A., Zenclussen, M.L., Zenclussen, A.C. (2023):
Intrauterine exposure to bisphenol A and benzophenone-3 affects fetal growth and impacts on uterine innate immune cells supporting pregnancy
Am. J. Reprod. Immunol. 89 (S1), 82 - 83
full text (doi)
Musiol, S., Harris, C.P., Karlina, R., Gostner, J.M., Rathkolb, B., Schnautz, B., Schneider, E., Mair, L., Elorduy Vergara, E., Flexeder, C., Koletzko, S., Bauer, C.-P., Schikowski, T., Berdel, D., von Berg, A., Herberth, G., Rozman, J., Hrabe de Angelis, M., Standl, M., Schmidt-Weber, C.B.., Ussar, S., Alessandrini, F. (2023):
Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice
Allergy 78 (5), 1218 - 1233
full text (doi)
Pfannes, R., Pierzchalski, A., Maddalon, A., Simion, A., Zouboulis, C.C., Behre, G., Zenclussen, A.C., Westphal, S., Fest, S., Herberth, G. (2023):
Characterization of post-vaccination SARS-CoV-2 T cell subtypes in patients with different hematologic malignancies and treatments
Front. Immunol. 14 , art. 1087996
full text (doi)
Pierzchalski, A., Zenclussen, A.C., Herberth, G. (2023):
OMIP-94: Twenty-four-color (thirty-marker) panel for deep immunophenotyping of immune cells in human peripheral blood
Cytom. Part A
full text (doi)
Prokopciuk, N., Juskiene, I., Tarasiuk, N., Franck, U., Kostiuk, O., Valiulis, A., Taminskiene, V., Valiulis, A. (2023):
On the additional risk for human health in the use of sandblasting of building walls
Environ. Sci. Pollut. Res. 30 (19), 56558 - 56568
full text (doi)
Schulz, J., Schilling, E., Fabian, C., Zenclussen, A.C., Stojanovska, V., Claus, C. (2023):
Dissecting rubella placental infection in an in vitro trophoblast model
Int. J. Mol. Sci. 24 (9), art. 7894
full text (doi)
Thiering, E., Markevych, I., Kress, S., Astell-Burt, T., Feng, X., Altug, H., Koletzko, S., Bauer, C.-P., von Berg, A., Berdel, D., Herberth, G., Schikowski, T., Heinrich, J., Standl, M. (2023):
Gene-environment interaction in the association of residential greenness and 25(OH) vitamin D
Environ. Pollut. 327 , art. 121519
full text (doi)
Thürmann, L., Klös, M., Mackowiak, S.D., Bieg, M., Bauer, T., Ishaque, N., Messingschlager, M., Herrmann, C., Röder, S., Bauer, M., Schäuble, S., Faessler, E., Hahn, U., Weichenhan, D., Mücke, O., Plass, C., Borte, M., von Mutius, E., Stangl, G.I., Lauener, R., Karvonen, A.M., Divaret-Chauveau, A., Riedler, J., Heinrich, J., Standl, M., von Berg, A., Schaaf, B., Herberth, G., Kabesch, M., Eils, R., Trump, S., Lehmann, I. (2023):
Global hypomethylation in childhood asthma identified by genome-wide DNA-methylation sequencing preferentially affects enhancer regions
Allergy
full text (doi)
Wang, M., Flexeder, C., Kilanowski, A., Kress, S., Herberth, G., Schikowski, T., Peters, A., Standl, M. (2023):
Changes in sleep duration and sleep difficulties from adolescence to young adulthood and the risk of obesity: Bidirectional evidence in the GINIplus and LISA studies
Sleep Med. 101 , 401 - 410
full text (doi)
Yin, Z., Schumacher, A., Zenclussen, A.C. (2023):
Sex-specific effect of bisphenol A, its substitutes and benzophenone-3 on T helper 1 cell differentiation
Am. J. Reprod. Immunol. 89 (S1), 83 - 84
full text (doi)

to index

Projects

We participate in the joint research project SaxoChiLD.

@SaxoChiLD

We participate in the joint research project
CoViPa.

@CoViPa