Dr. Ivonne Nijenhuis

Curriculum Vitae

Research interests

My research in the Department of Isotope Biogeochemistry focused on the anaerobic biotransformation of halogenated organic contaminants and the application of stable isotope concepts. The main objectives of this research are 1) understanding of microbial transformation of chlorinated and brominated ethenes and ethanes, halogenated pesticides, e.g. hexachlorocyclohexane, and pharmaceuticals, e.g. diclofenac, and 2) development and application of multi-element compound-specific stable isotope (C, Cl, Br, H) fractionation as a tool to analyse microbial reactions and biotransformation in situ.

Projects

2011-2019 the DFG Forschergruppe "FOR1530 'Anaerobic Dehalogenation: Organisms, Biochemistry and (Eco-) Physiology'" links research groups in Jena, Halle and Leipzig. Within this project, I was in charge of sub-project 05: 'Characterisation of microbial dehalogenation using compound specific stable isotope analysis'.

Within the European Union FP7 project "GENESIS" we investigated how biogeochemical processes affect natural attenuation of chlorinated benzenes and are focusing on the microbial community involved in contaminant biotransformation.

From 2010-2015, I coordinated the European Union FP7 'People' programme Initial Training Network "CSI:ENVIRONMENT". In this project, 10 Partners and 4 Associated Partners from 9 European countries will work on 'Isotope forensics meets biogeochemistry - linking sources and sinks of organic contaminants by compound specific isotope investigation'.

2012-2014, Joint German-Israeli Water Technology Programme “Development of innovative tools for the assessment of in situ biodegradation of organobromine contaminant in groundwater” – INTIME. In this 3 year project we will investigate the application of CSIA for assessment of the natural attenuation of brominated groundwater contaminants.

Publications (in co-operation with the UFZ)

• Bashir, S., Fischer, A., Nijenhuis, I., Richnow, H.H. (2013):
  Enantioselective carbon stable isotope fractionation of hexachlorocyclohexane during aerobic biodegradation by Sphingobium spp.
  Environ. Sci. Technol. 47 (20), 11432 - 11439
  full text (doi)
• Bashir, S., Kuntze, K., Vogt, C., Nijenhuis, I. (2018):
  Anaerobic biotransformation of hexachlorocyclohexane isomers by Dehalococcoides species and an enrichment culture
  Biodegradation 29 (4), 409 - 418
  full text (doi)
• Bin Hudari, M.S., Richnow, H., Vogt, C., Nijenhuis, I. (2022):
  Effect of temperature on microbial reductive dehalogenation of chlorinated ethenes: a review
  FEMS Microbiol. Ecol. 98 (9), fiac081
  full text (doi)
• Birkigt, J., Gilevska, T., Ricken, B., Richnow, H.-H., Vione, D., Corvini, P.F.-X., Nijenhuis, I., Cichocka, D. (2015):
  Carbon stable isotope fractionation of sulfamethoxazole during biodegradation by Microbacterium sp. strain BR1 and upon direct photolysis
  Environ. Sci. Technol. 49 (10), 6029 - 6036
  full text (doi)
• Birkigt, J., Stumpp, C., Małoszewski, P., Nijenhuis, I. (2018):
  Evaluation of the hydrological flow paths in a gravel bed filter modeling a horizontal subsurface flow wetland by using a multi-tracer experiment
  Sci. Total Environ. 621 , 265 - 272
  full text (doi)
• Cichocka, D., Imfeld, G., Richnow, H.H., Nijenhuis, I. (2008):
  Variability in microbial carbon isotope fractionation of tetra- and trichloroethene upon reductive dechlorination
  Chemosphere 71 (4), 639 - 648
  full text (doi)
• Cichocka, D., Nikolausz, M., Haest, P.J., Nijenhuis, I. (2010):
  Tetrachloroethene conversion to ethene by a Dehalococcoides-containing enrichment culture from Bitterfeld
  FEMS Microbiol. Ecol. 72 (2), 297 - 310
  full text (doi)
• Cichocka, D., Siegert, M., Imfeld, G., Andert, J., Beck, K., Diekert, G., Richnow, H.H., Nijenhuis, I. (2007):
  Factors controlling the carbon isotope fractionation of tetra- and trichloroethene during reductive dechlorination by Sulfurospirillum ssp. and Desulfitobacterium sp. strain PCE-S
  FEMS Microbiol. Ecol. 62 (1), 98 - 107
  full text (doi)
• Duldhardt, I., Gaebel, J., Chrzanowski, Ł., Nijenhuis, I., Schauer, F., Heipieper, H.J. (2010):
  Adaptation of anaerobically grown Thauera aromatica, Geobacter sulfurreducens and Desulfococcus multivorans to organic solvents on the level of membrane fatty acid composition
  Microb. Biotechnol. 3 (2), 201 - 209
  full text (doi)
• Duldhardt, I., Nijenhuis, I., Schauer, F., Heipieper, H.J. (2007):
  Anaerobically grown Thauera aromatica, Desulfococcus multivorans, Geobacter sulfurreducens are more sensitive towards organic solvents than aerobic bacteria
  Appl. Microbiol. Biotechnol. 77 (3), 705 - 711
  full text (doi)
• Elsayed, O.F., Maillard, E., Vuilleumier, S., Nijenhuis, I., Richnow, H.H., Imfeld, G. (2014):
  Using compound-specific isotope analysis to assess the degradation of chloroacetanilide herbicides in lab-scale wetlands
  Chemosphere 99 , 89 - 95
  full text (doi)
• Ewald, E.-M., Wagner, A., Nijenhuis, I., Richnow, H.H., Lechner, U. (2007):
  Microbial dehalogenation of trichlorinated dibenzo-p-dioxins by a Dehalococcoides-containing mixed culture is coupled to carbon isotope fractionation
  Environ. Sci. Technol. 41 (22), 7744 - 7751
  full text (doi)
• Fennell, D.E., Nijenhuis, I., Wilson, S.F., Zinder, S.H., Häggblom, M.M. (2004):
  Dehalococcoides ethenogenes strain 195 reductively dechlorinates diverse chlorinated aromatic pollutants
  Environ. Sci. Technol. 38 (7), 2075 - 2081
  full text (doi)
• Filippini, M., Amorosi, A., Campo, B., Herrero-Martìn, S., Nijenhuis, I., Parker, B.L., Gargini, A. (2016):
  Origin of VC-only plumes from naturally enhanced dechlorination in a peat-rich hydrogeologic setting
  J. Contam. Hydrol. 192 , 129 - 139
  full text (doi)
• Filippini, M., Nijenhuis, I., Kümmel, S., Chiarini, V., Crosta, G., Richnow, H.H., Gargini, A. (2018):
  Multi-element compound specific stable isotope analysis of chlorinated aliphatic contaminants derived from chlorinated pitches
  Sci. Total Environ. 640-641 , 153 - 162
  full text (doi)
• Filippini, M., Stumpp, C., Nijenhuis, I., Richnow, H.H., Gargini, A. (2015):
  Evaluation of aquifer recharge and vulnerability in an alluvial lowland using environmental tracers
  J. Hydrol. 529 , 1657 - 1668
  full text (doi)
• Fletcher, K.E., Löffler, F.E., Richnow, H.-H., Nijenhuis, I. (2009):
  Stable carbon isotope fractionation of 1,2-Dichloropropane during dichloroelimination by Dehalococcoides populations
  Environ. Sci. Technol. 43 (18), 6915 - 6919
  full text (doi)
• Fletcher, K.E., Nijenhuis, I., Richnow, H.-H., Löffler, F.E. (2011):
  Stable carbon isotope enrichment factors for cis-1,2-dichloroethene and vinyl chloride reductive dechlorination by Dehalococcoides
  Environ. Sci. Technol. 45 (7), 2951 - 2957
  full text (doi)
• Franke, S., Kümmel, S., Nijenhuis, I. (2018):
  Liquid chromatography/isotope ratio mass spectrometry analysis of halogenated benzoates for characterization of the underlying degradation reaction in Thauera chlorobenzoica CB‐1^T
  Rapid Commun. Mass Spectrom. 32 (11), 906 - 912
  full text (doi)
• Franke, S., Lihl, C., Renpenning, J., Elsner, M., Nijenhuis, I. (2017):
  Triple-element compound-specific stable isotope analysis of 1,2-dichloroethane for characterization of the underlying dehalogenation reaction in two Dehalococcoides mccartyi strains
  FEMS Microbiol. Ecol. 93 (12), fix137
  full text (doi)
• Franke, S., Seidel, K., Adrian, L., Nijenhuis, I. (2020):
  Dual element (C/Cl) isotope analysis indicates distinct mechanisms of reductive dehalogenation of chlorinated ethenes and dichloroethane in Dehalococcoides mccartyi strain BTF08 with defined reductive dehalogenase inventories
  Front. Microbiol. 11 , art. 1507
  full text (doi)
• Gilevska, T., Sullivan Ojeda, A., Renpenning, J., Kümmel, S., Gehre, M., Nijenhuis, I. (2020):
  Requirements for chromium reactors for use in the determination of H isotopes in compound-specific stable isotope analysis cf chlorinated compounds
  Anal. Chem. 92 (3), 2383 - 2387
  full text (doi)
• Günthel, M., Klawonn, I., Woodhouse, J., Bižić, M., Ionescu, D., Ganzert, L., Kümmel, S., Nijenhuis, I., Zoccarato, L., Grossart, H.-P., Tang, K.W. (2020):
  Photosynthesis‐driven methane production in oxic lake water as an important contributor to methane emission
  Limnol. Oceanogr. 65 (12), 2853 - 2865
  full text (doi)
• Herrero, J., Puigserver, D., Nijenhuis, I., Kuntze, K., Carmona, J.M. (2019):
  Combined use of ISCR and biostimulation techniques in incomplete processes of reductive dehalogenation of chlorinated solvents
  Sci. Total Environ. 648 , 819 - 829
  full text (doi)
• Herrero, J., Puigserver, D., Nijenhuis, I., Kuntze, K., Carmona, J.M. (2022):
  Key factors controlling microbial distribution on a DNAPL source area
  Environ. Sci. Pollut. Res. 29 (1), 1508 - 1520
  full text (doi)
• Herrero, J., Puigserver, D., Nijenhuis, I., Kuntze, K., Parker, B.L., Carmona, J.M. (2021):
  The role of ecotones in the dehalogenation of chloroethenes in alluvial fan aquifers
  Environ. Sci. Pollut. Res. 28 (21), 26871 - 26884
  full text (doi)
• Herrero-Martín, S., Nijenhuis, I., Richnow, H.H., Gehre, M. (2015):
  Coupling of a headspace autosampler with a programmed temperature vaporizer for stable carbon and hydrogen isotope analysis of volatile organic compounds at microgram per liter concentrations
  Anal. Chem. 87 (2), 951 - 959
  full text (doi)
• Holliger, C., Nijenhuis, I. (2018):
  Special issue on anaerobic biological dehalogenation. Editorial
  FEMS Microbiol. Ecol. 94 (6), fiy054
  full text (doi)
• Horna-Gray, I., Lopez, N.A., Nijenhuis, I., Ahn, Y., Richnow, H.H., Häggblom, M.M. (2020):
  Reductive debromination by sponge-associated anaerobic bacteria coupled to carbon isotope fractionation
  Int. Biodeterior. Biodegrad. 155 , art. 105093
  full text (doi)
• Imfeld, G., Aragonés, C.E., Fetzer, I., Mészáros, E., Zeiger, S., Nijenhuis, I., Nikolausz, M., Delerce, S., Richnow, H.H. (2010):
  Characterization of microbial communities in the aqueous phase of a constructed model wetland treating 1,2-dichloroethene-contaminated groundwater
  FEMS Microbiol. Ecol. 72 (1), 74 - 88
  full text (doi)
• Imfeld, G., Nijenhuis, I., Nikolausz, M., Zeiger, S., Paschke, H., Drangmeister, J., Grossmann, J., Richnow, H.H., Weber, S. (2008):
  Assessment of in situ degradation of chlorinated ethenes and bacterial community structure in a complex contaminated groundwater system
  Water Res. 42 (4-5), 871 - 882
  full text (doi)
• Imfeld, G., Pieper, H., Shani, N., Rossi, P., Nikolausz, M., Nijenhuis, I., Paschke, H., Weiß, H., Richnow, H.H. (2011):
  Characterization of groundwater microbial communities, dechlorinating bacteria, and in situ biodegradation of chloroethenes along a vertical gradient
  Water Air Soil Pollut. 221 (1-4), 107 - 122
  full text (doi)
• Jin, B., Nijenhuis, I., Rolle, M. (2018):
  Simulation of dual carbon–bromine stable isotope fractionation during 1,2-dibromoethane degradation
  Isot. Environ. Health Stud. 54 (4), 418 - 434
  full text (doi)
• Kaschl, A., Vogt, C., Uhlig, S., Nijenhuis, I., Weiß, H., Kästner, M., Richnow, H.H. (2005):
  Isotopic fractionation indicates anaerobic monochlorobenzene biodegradation
  Environ. Toxicol. Chem. 24 (6), 1315 - 1324
  full text (doi)
• Kästner, M., Fischer, A., Nijenhuis, I., Geyer, R., Stelzer, N., Bombach, P., Tebbe, C.C., Richnow, H.H. (2006):
  Assessment of microbial in situ activity in contaminated aquifers
  Eng. Life Sci. 6 (3), 234 - 251
  full text (doi)
• Kaufhold, T., Schmidt, M., Cichocka, D., Nikolausz, M., Nijenhuis, I. (2013):
  Dehalogenation of diverse halogenated substrates by a highly enriched Dehalococcoides-containing culture derived from the contaminated mega-site in Bitterfeld
  FEMS Microbiol. Ecol. 83 (1), 176 - 188
  full text (doi)
• Kjellerup, B.V., Nijenhuis, I., Rossetti, S. (2022):
  Editorial: Thematic issue on anaerobic biological dehalogenation
  FEMS Microbiol. Ecol. 98 (11), fiac108
  full text (doi)
• Knight, V.K., Nijenhuis, I., Kerkhof, L.J., Häggblom, M.M. (2002):
  Degradation of aromatic compounds coupled to selenate reduction
  Geomicrobiol. J. 19 (1), 77 - 86
  full text (doi)
• Kret, E., Kiecak, A., Malina, G., Nijenhuis, I., Postawa, A. (2015):
  Identification of TCE and PCE sorption and biodegradation parameters in a sandy aquifer for fate and transport modelling: batch and column studies
  Environ. Sci. Pollut. Res. 22 (13), 9877 - 9888
  full text (doi)
• Kruse, S., Türkowsky, D., Birkigt, J., Matturro, B., Franke, S., Jehmlich, N., von Bergen, M., Westermann, M., Rossetti, S., Nijenhuis, I., Adrian, L., Diekert, G., Goris, T. (2021):
  Interspecies metabolite transfer and aggregate formation in a co-culture of Dehalococcoides and Sulfurospirillum dehalogenating tetrachloroethene to ethene
  ISME J. 15 (6), 1794 - 1809
  full text (doi)
• Kuntze, K., Kozell, A., Richnow, H.H., Halicz, L., Nijenhuis, I., Gelman, F. (2016):
  Dual carbon–bromine stable isotope analysis allows distinguishing transformation pathways of ethylene dibromide
  Environ. Sci. Technol. 50 (18), 9855 - 9863
  full text (doi)
• Langenhoff, A., Nijenhuis, I., Tan, N.C.G., Briglia, M., Zehnder, A.J.B., Schraa, G. (1997):
  Characterisation of a manganese-reducing, toluene-degrading enrichment culture
  FEMS Microbiol. Ecol. 24 (2), 113 - 125
  full text (doi)
• Lian, S., Nikolausz, M., Nijenhuis, I., Leite, A.F., Richnow, H.H. (2018):
  Biotransformation and inhibition effects of hexachlorocyclohexanes during biogas production from contaminated biomass characterized by isotope fractionation concepts
  Bioresour. Technol. 250 , 683 - 690
  full text (doi)
• Lian, S., Nikolausz, M., Nijenhuis, I., Nunes da Rocha, U., Liu, B., Borim Corrêa, F., Saraiva, J.P., Richnow, H.H. (2020):
  Biotransformation of hexachlorocyclohexanes contaminated biomass for energetic utilization demonstrated in continuous anaerobic digestion system
  J. Hazard. Mater. 384 , art. 121448
  full text (doi)
• Lihl, C., Douglas, L.M., Franke, S., Pérez-de-Mora, A., Meyer, A.H., Daubmeier, M., Edwards, E.A., Nijenhuis, I., Sherwood Lollar, B., Elsner, M. (2019):
  Mechanistic dichotomy in bacterial trichloroethene dechlorination revealed by carbon and chlorine isotope effects
  Environ. Sci. Technol. 53 (8), 4245 - 4254
  full text (doi)
• Liu, F., Cichocka, D., Nijenhuis, I., Richnow, H.H., Fennell, D.E. (2010):
  Carbon isotope fractionation during dechlorination of 1,2,3,4-tetrachlorodibenzo-p-dioxin by a Dehalococcoides-containing culture
  Chemosphere 80 (10), 1113 - 1119
  full text (doi)
• Liu, Y., Bashir, S., Stollberg, R., Trabitzsch, R., Weiß, H., Paschke, H., Nijenhuis, I., Richnow, H.-H. (2017):
  Compound specific and enantioselective stable isotope analysis as tools to monitor transformation of hexachlorocyclohexane (HCH) in a complex aquifer system
  Environ. Sci. Technol. 51 (16), 8909 - 8916
  full text (doi)
• Liu, Y., Fu, J., Wu, L., Kümmel, S., Nijenhuis, I., Richnow, H.H. (2022):
  Characterization of hexachlorocyclohexane isomer dehydrochlorination by LinA1 and LinA2 using multi-element compound-specific stable isotope analysis
  Environ. Sci. Technol. 56 (23), 16848 - 16856
  full text (doi)
• Liu, Y., Kümmel, S., Yao, J., Nijenhuis, I., Richnow, H.-H. (2020):
  Dual C–Cl isotope analysis for characterizing the anaerobic transformation of α, β, γ, and δ-hexachlorocyclohexane in contaminated aquifers
  Water Res. 184 , art. 116128
  full text (doi)
• Liu, Y., Renpenning, J., Nijenhuis, I., Richnow, H.-H. (2020):
  Dual C–Cl isotope analysis for characterizing the reductive dechlorination of α- and γ-hexachlorocyclohexane by two Dehalococcoides mccartyi strains and an enrichment culture
  Environ. Sci. Technol. 54 (12), 7250 - 7260
  full text (doi)
• Liu, Y., Wu, L., Kohli, P., Kumar, R., Stryhanyuk, H., Nijenhuis, I., Lal, R., Richnow, H.-H. (2019):
  Enantiomer and carbon isotope fractionation of α-hexachlorocyclohexane by Sphingobium indicum strain B90A and the corresponding enzymes
  Environ. Sci. Technol. 53 (15), 8715 - 8724
  full text (doi)
• Lünsmann, V., Kappelmeyer, U., Taubert, A., Nijenhuis, I., von Bergen, M., Heipieper, H.J., Müller, J.A., Jehmlich, N. (2016):
  Aerobic toluene degraders in the rhizosphere of a constructed wetland model show diurnal polyhydroxyalkanoate metabolism
  Appl. Environ. Microb. 82 (14), 4126 - 4132
  full text (doi)
• Marco-Urrea, E., Nijenhuis, I., Adrian, L. (2011):
  Transformation and carbon isotope fractionation of tetra- and trichloroethene to Trans-Dichloroethene by Dehalococcoides sp. strain CBDB1
  Environ. Sci. Technol. 45 (4), 1555 - 1562
  full text (doi)
• Martínez-Lavanchy, P.M., Chen, Z., Lünsmann, V., Marin-Cevada, V., Vilchez-Vargas, R., Pieper, D.H., Reiche, N., Kappelmeyer, U., Imparato, V., Junca, H., Nijenhuis, I., Müller, J.A., Kuschk, P., Heipieper, H.J. (2015):
  Microbial toluene removal in hypoxic model constructed wetlands occurs predominantly via the ring monooxygenation pathway
  Appl. Environ. Microb. 81 (18), 6241 - 6252
  full text (doi)
• Martínez-Lavanchy, P.M., Dohrmann, A.B., Imfeld, G., Trescher, K., Tebbe, C.C., Richnow, H.-H., Nijenhuis, I. (2011):
  Detection of monochlorobenzene metabolizing bacteria under anoxic conditions by DNA-stable isotope probing
  Biodegradation 22 (5), 973 - 982
  full text (doi)
• Martínez-Lavanchy, P.M., Müller, C., Nijenhuis, I., Kappelmeyer, U., Buffing, M., McPherson, K., Heipieper, H.J. (2010):
  High stability and fast recovery of expression of the TOL plasmid-carried toluene catabolism genes of Pseudomonas putida mt-2 under conditions of oxygen limitation and oscillation
  Appl. Environ. Microb. 76 (20), 6715 - 6723
  full text (doi)
• Maymó-Gatell, X., Nijenhuis, I., Zinder, S.H. (2001):
  Reductive dechlorination of cis-1,2-dichlorethene and vinyl chloride by "Dehalococcoides ethenogenes"
  Environ. Sci. Technol. 35 (3), 516 - 521
  full text (doi)
• Mendler, A., Geier, F., Haange, S.-B., Pierzchalski, A., Krause, J.L., Nijenhuis, I., Froment, J., Jehmlich, N., Berger, U., Ackermann, G., Rolle-Kampczyk, U., von Bergen, M., Herberth, G. (2020):
  Mucosal-associated invariant T-Cell (MAIT) activation is altered by chlorpyrifos- and glyphosate-treated commensal gut bacteria
  J. Immunotoxicol. 17 (1), 10 - 20
  full text (doi)
• Mészáros, E., Imfeld, G., Nikolausz, M., Nijenhuis, I. (2013):
  Occurrence of Dehalococcoides and reductive dehalogenase genes in microcosms, a constructed wetland and groundwater from a chlorinated ethene contaminated field site as indicators for in situ reductive dehalogenation
  Water Air Soil Pollut. 224 (11), art. 1768
  full text (doi)
• Mortan, S.H., Martín-González, L., Vicent, T., Caminal, G., Nijenhuis, I., Adrian, L., Marco-Urrea, E. (2017):
  Detoxification of 1,1,2-trichloroethane to ethene in a bioreactor co-culture of Dehalogenimonas and Dehalococcoides mccartyi strains
  J. Hazard. Mater. 331 , 218 - 225
  full text (doi)
• Nijenhuis, I., Andert, J., Beck, K., Kästner, M., Diekert, G., Richnow, H.H. (2005):
  Stable isotope fractionation of tetrachloroethene during reductive dechlorination by Sulfurospirillum multivorans and Desulfitobacterium sp. strain PCE-S and abiotic reactions with cyanocobalamin
  Appl. Environ. Microb. 71 (7), 3413 - 3419
  full text (doi)
• Nijenhuis, I., Andert, J., Beck, K., Vieth, A., Kästner, M., Richnow, H.H., Diekert, G. (2004):
  Use of stable isotope fractionation for the assessment of bioattenuation of chlorinated ethenes
  In: Verstraete, W. (ed.)
  European Symposium on Environmental Biotechnology : proceedings of the European Symposium on Environmental Biotechnology, ESEB 2004, 25-28 April 2004, Oostende, Belgium
  Balkema, Leiden, p. 209 - 212
• Nijenhuis, I., Kuntze, K. (2016):
  Anaerobic microbial dehalogenation of organohalides — state of the art and remediation strategies
  Curr. Opin. Biotechnol. 38 , 33 - 38
  full text (doi)
• Nijenhuis, I., Martínez, P., Junca, H., Stelzer, N., Imfeld, G., Weber, S., Richnow, H. (2009):
  In situ investigation of microbial diversity and anaerobic chlorobenzene degradation along a vertical gradient
  Geochim. Cosmochim. Acta 73 (13 Suppl.), A943
  full text (doi)
• Nijenhuis, I., Nikolausz, M., Köth, A., Felföldi, T., Weiß, H., Drangmeister, J., Großmann, J., Kästner, M., Richnow, H.H. (2007):
  Assessment of the natural attenuation of chlorinated ethenes in an anaerobic contaminated aquifer in the Bitterfeld/Wolfen area using stable isotope techniques, microcosm studies and molecular biomarkers
  Chemosphere 67 (2), 300 - 311
  full text (doi)
• Nijenhuis, I., Renpenning, J., Kümmel, S., Richnow, H.H., Gehre, M. (2016):
  Recent advances in multi-element compound-specific stable isotope analysis of organohalides: Achievements, challenges and prospects for assessing environmental sources and transformation
  Trends Environ. Anal. Chem. 11 , 1 - 8
  full text (doi)
• Nijenhuis, I., Richnow, H.H. (2016):
  Stable isotope fractionation concepts for characterizing biotransformation of organohalides
  Curr. Opin. Biotechnol. 41 , 108 - 113
  full text (doi)
• Nijenhuis, I., Schmidt, M., Pellegatti, E., Paramatti, E., Richnow, H.-H., Gargini, A. (2013):
  A stable isotope approach for source apportionment of chlorinated ethene plumes at a complex multi-contamination events urban site
  J. Contam. Hydrol. 153 , 92 - 105
  full text (doi)
• Nijenhuis, I., Stelzer, N., Kästner, M., Richnow, H.-H. (2007):
  Sensitive detection of anaerobic monochlorobenzene degradation using stable isotope tracers
  Environ. Sci. Technol. 41 (11), 3836 - 3842
  full text (doi)
• Nijenhuis, I., Stollberg, R., Lechner, U. (2018):
  Anaerobic microbial dehalogenation and its key players in the contaminated Bitterfeld-Wolfen megasite
  FEMS Microbiol. Ecol. 94 (4), fiy012
  full text (doi)
• Nijenhuis, I., Uhlig, S., Kaschl, A., Nikolausz, M., Kästner, M. (2004):
  Evidence for in situ natural attenuation of monochlorobenzene and chlorinated ethenes in an anaerobic contaminated aquifer
  Abstr. Paper Am. Chem. Soc. 228 , U608 - U609
• Nijenhuis, I., Zinder, S.H. (2005):
  Characterization of hydrogenase and reductive dehalogenase activities of Dehalococcoides ethenogenes strain 195
  Appl. Environ. Microb. 71 (3), 1664 - 1667
  full text (doi)
• Nikolausz, M., Kappelmeyer, U., Nijenhuis, I., Ziller, K., Kästner, M. (2005):
  Molecular characterization of dichloromethane-degrading Hyphomicrobium strains using 16S rDNA and DCM dehalogenase gene sequences
  Syst. Appl. Microbiol. 28 (7), 582 - 587
  full text (doi)
• Nikolausz, M., Nijenhuis, I., Ziller, K., Richnow, H.H., Kästner, M. (2006):
  Stable carbon isotope fractionation during degradation of dichloromethane by methylotrophic bacteria
  Environ. Microbiol. 8 (1), 156 - 164
  full text (doi)
• Peng, P., Lu, Y., Bosma, T.N.P., Nijenhuis, I., Nijsse, B., Shetty, S.A., Ruecker, A., Umanets, A., Ramiro-Garcia, J., Kappler, A., Sipkema, D., Smidt, H., Atashgahi, S. (2020):
  Metagenomic- and cultivation-based exploration of anaerobic chloroform biotransformation in hypersaline sediments as natural source of chloromethanes
  Microorganisms 8 (5), art. 665
  full text (doi)
• Phillips, E., Bulka, O., Picott, K., Kümmel, S., Edwards, E., Nijenhuis, I., Gehre, M., Dworatzek, S., Webb, J., Sherwood Lollar, B. (2022):
  Investigation of active site amino acid influence on carbon and chlorine isotope fractionation during reductive dechlorination
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• Pöritz, M., Schiffmann, C.L., Hause, G., Heinemann, U., Seifert, J., Jehmlich, N., von Bergen, M., Nijenhuis, I., Lechner, U. (2015):
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• Renpenning, J., Rapp, I., Nijenhuis, I. (2015):
  Substrate hydrophobicity and cell composition influence the extent of rate limitation and masking of isotope fractionation during microbial reductive dehalogenation of chlorinated ethenes
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• Schmidt, M., Lege, S., Nijenhuis, I. (2014):
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• Schmidt, M., Wolfram, D., Birkigt, J., Ahlheim, J., Paschke, H., Richnow, H.-H., Nijenhuis, I. (2014):
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  Org. Geochem. 37 (10), 1394 - 1410
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• Stelzer, N., Imfeld, G., Thullner, M., Lehmann, J., Poser, A., Richnow, H.-H., Nijenhuis, I. (2009):
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• Vogel, M., Nijenhuis, I., Lloyd, J., Boothman, C., Pöritz, M., Mackenzie, K. (2018):
  Combined chemical and microbiological degradation of tetrachloroethene during the application of Carbo-Iron at a contaminated field site
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• Woods, A., Kuntze, K., Gelman, F., Halicz, L., Nijenhuis, I. (2018):
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• Zhang, N., Bashir, S., Qin, J., Schindelka, J., Fischer, A., Nijenhuis, I., Herrmann, H., Wick, L.Y., Richnow, H.H. (2014):
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