Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.copbio.2015.11.009
Title (Primary) Anaerobic microbial dehalogenation of organohalides — state of the art and remediation strategies
Author Nijenhuis, I.; Kuntze, K.
Source Titel Current Opinion in Biotechnology
Year 2016
Department ISOBIO
Volume 38
Page From 33
Page To 38
Language englisch
UFZ wide themes RU3;
Abstract Contamination and remediation of groundwater with halogenated organics and understanding of involved microbial reactions still poses a challenge. Over the last years, research in anaerobic microbial dehalogenation has advanced in many aspects providing information about the reaction, physiology of microorganisms as well as approaches to investigate the activity of microorganisms in situ. Recently published crystal structures of reductive dehalogenases (Rdh), heterologous expression systems and advanced analytical, proteomic and stable isotope approaches allow addressing the overall reaction and specific enzymes as well as co-factors involved during anaerobic microbial dehalogenation. In addition to Dehalococcoides spp., Dehalobacter and Dehalogenimonas strains have been recognized as important and versatile organohalide respirers. Together, these provide perspectives for integrated concepts allowing to improve and monitor in situ biodegradation.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=16991
Nijenhuis, I., Kuntze, K. (2016):
Anaerobic microbial dehalogenation of organohalides — state of the art and remediation strategies
Curr. Opin. Biotechnol. 38 , 33 - 38 10.1016/j.copbio.2015.11.009