Lorenz Adrian
Prof. Dr. rer nat
Department head (shared)
Curriculum Vitae
| 2020–now | Department head (shared) at UFZ Leipzig, Department Environmental Biotechnology |
| 2017–now | Professorship for Geobiotechnology at TU Berlin |
| 2013–20 | Senior Scientist at UFZ Leipzig, Department Isotope Biogeochemistry, working group "Functional Genomics", since 2017 "Geobiochemistry" |
| 2008–13 | Head of an ERC group, Department Isotope Biogeochemistry |
| 2008–10 | Guest Professor for Applied Biochemistry, TU Berlin |
| 2007 | Postdoc Rensselaer Polytechnic Institute, NY, USA |
| 2006 | Habilitation, TU Berlin |
| 2003 | Postdoc Cornell University, NY, USA |
| 1999 | PhD, TU Berlin |
| 1993 | Diploma Biology, Universtät Bonn and University of Manchester, UK |
Research
Our research focusses on the molecular investigation of anaerobic microbial proceses that can be applied to mitigate climate change or remediate contaminated environments. For detailed information on our research please visit the list of Research groups at our department Environmental Biotechnology or our research summary at TU Berlin, Chair for Geobiotechnology
Teaching
All our teaching is at the Technische Universität Berlin for the Master courses Biotechnology and Environmental Engineering. For updated versions see our teaching section at the Chair of Geobiotechnology.
Dr. Lorenz Adrian offers an integrated course (lecture series + seminar) on Geobiotechnology.
We commonly offer a one-week lab course on Geobiotechnology in our labs in Leipzig for students of the TU Berlin courses Biotechnology or Technischer Umweltschutz (Dr. Deobald, Dr. Adrian).
Dr. Darja Deobald offers an integrated lecture on Enzyme Technology for Biotechnoloy students.
Dr. Chang Ding offers an integrated course on Molecular Environmental Engineering encompassing 6 lectures and 3-4 days practical course in Leipzig.
The integrated course of Dr. Karolina Nowak on Isotope Biotechnology during the winter semester at TU Berlin for students of the course Biotechnology is discontinued since 2022.
Publications
see also GoogleSchoolar
2023 (3)
- Ouyang, W.-Y., Kümmel, S., Adrian, L., Zhu, Y.-G., Richnow, H.H. (2023):
Carbon and hydrogen stable isotope fractionation of sulfamethoxazole during anaerobic transformation catalyzed by Desulfovibrio vulgaris Hildenborough
Chemosphere 311, Part 2 , art. 136923
full text (doi) - Reino, C., Ding, C., Adrian, L. (2023):
Continuous cultivation of Dehalococcoides mccartyi with brominated tyrosine avoids toxic byproducts and gives tight reactor control
Water Res. 229 , art. 119396
full text (doi) - Ude, E.O., Haas, J., Kaiyoum, M.K., Ding, C., Adrian, L. (2023):
Effects of reducing, stabilizing, and antibiotic agents on “Candidatus Kuenenia stuttgartiensis”
Appl. Microbiol. Biotechnol. 107 , 1829 - 1843
full text (doi)
2022 (6)
- Deobald, D., Adrian, L. (2022):
Metallomics of the quinone-free respiration system of Dehalococcoides mccartyi indicates the presence of molybdenum, nickel, iron and cobalt in the respiratory complex
Biochim. Biophys. Acta-Bioenerg. 1863 (Suppl.), art. 148768
full text (doi) - Eziuzor, S.C., Borim Corrêa, F., Peng, S., Schultz, J., Kleinsteuber, S., Nunes da Rocha, U., Adrian, L., Vogt, C. (2022):
Structure and functional capacity of a benzene‐mineralizing, nitrate‐reducing microbial community
J. Appl. Microbiol. 132 (4), 2795 - 2811
full text (doi) - Soboh, B., Adrian, L., Stripp, S.T. (2022):
An in vitro reconstitution system to monitor iron transfer to the active site during the maturation of [NiFe]-hydrogenase
J. Biol. Chem. 298 (9), art. 102291
full text (doi) - Vasileiadis, S., Perruchon, C., Scheer, B., Adrian, L., Steinbach, N., Trevisan, M., Plaza-Bolaños, P., Agüera, A., Chatzinotas, A., Karpouzas, D.G. (2022):
Nutritional inter-dependencies and a carbazole-dioxygenase are key elements of a bacterial consortium relying on a Sphingomonas for the degradation of the fungicide thiabendazole
Environ. Microbiol. 24 (11), 5105 - 5122
full text (doi) - Wan, J., Chen, K., Chen, J., Qin, Z., Adrian, L., Shen, C. (2022):
Enhanced perchloroethene dechlorination by humic acids via increasing the dehalogenase activity of Dehalococcoides strains
FEMS Microbiol. Ecol. 98 (4), fiac034
full text (doi) - Zhang, H., Quintana, J., Ütkür, K., Adrian, L., Hawer, H., Mayer, K., Gong, X., Castanedo, L., Schulten, A., Janina, N., Peters, M., Wirtz, M., Brinkmann, U., Schaffrath, R., Krämer, U. (2022):
Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis
Nat. Commun. 13 , art. 4009
full text (doi)
2021 (13)
- Budhraja, R., Karande, S., Ding, C., Ullrich, M.K., Wagner, S., Reemtsma, T., Adrian, L. (2021):
Characterization of membrane-bound metalloproteins in the anaerobic ammonium-oxidizing bacterium “Candidatus Kuenenia stuttgartiensis” strain CSTR1
Talanta 223 (Part 2), art. 121711
full text (doi) - Chen, S.-C., Budhraja, R., Adrian, L., Calabrese, F., Stryhanyuk, H., Musat, N., Richnow, H.-H., Duan, G.-L., Zhu, Y.-G., Musat, F. (2021):
Novel clades of soil biphenyl degraders revealed by integrating isotope probing, multi-omics, and single-cell analyses
ISME J. 15 (12), 3508 - 3521
full text (doi) - Kruse, S., Türkowsky, D., Birkigt, J., Matturro, B., Franke, S., Jehmlich, N., von Bergen, M., Westermann, M., Rossetti, S., Nijenhuis, I., Adrian, L., Diekert, G., Goris, T. (2021):
Interspecies metabolite transfer and aggregate formation in a co-culture of Dehalococcoides and Sulfurospirillum dehalogenating tetrachloroethene to ethene
ISME J. 15 (6), 1794 - 1809
full text (doi) - Lupacchini, S., Appel, J., Stauder, R., Bolay, P., Klähn, S., Lettau, E., Adrian, L., Lauterbach, L., Bühler, B., Schmid, A., Toepel, J. (2021):
Rewiring cyanobacterial photosynthesis by the implementation of an oxygen-tolerant hydrogenase
Metab. Eng. 68 , 199 - 209
full text (doi) - Mösbauer, K., Fritsch, V.N., Adrian, L., Bernhardt, J., Gruhlke, M.C.H., Slusarenko, A.J., Niemeyer, D., Antelmann, H. (2021):
The effect of allicin on the proteome of SARS-CoV-2 infected Calu-3 cells
Front. Microbiol. 12 , art. 746795
full text (doi) - Nguyen, A.V., Lai, B., Adrian, L., Krömer, J.O. (2021):
The anoxic electrode-driven fructose catabolism of Pseudomonas putida KT2440
Microb. Biotechnol. 14 (4), 1784 - 1796
full text (doi) - Ouyang, W.-Y., Birkigt, J., Richnow, H.H., Adrian, L. (2021):
Anaerobic transformation and detoxification of sulfamethoxazole by sulfate-reducing enrichments and Desulfovibrio vulgaris
Environ. Sci. Technol. 55 (1), 271 - 282
full text (doi) - Shahryari, S., Talaee, M., Haghbeen, K., Adrian, L., Vali, H., Shahbani Zahiri, H., Noghabi, K.A. (2021):
New provisional function of OmpA from Acinetobacter sp. strain SA01 based on environmental challenges
mSystems 6 (1), e01175-20
full text (doi) - Sharma, M., Singh, D.N., Budhraja, R., Sood, P., Rawat, C.D., Adrian, L., Richnow, H.-H., Singh, Y., Negi, R.K., Lal, R. (2021):
Comparative proteomics unravelled the hexachlorocyclohexane (HCH) isomers specific responses in an archetypical HCH degrading bacterium Sphingobium indicum B90A
Environ. Sci. Pollut. Res. 28 (30), 41380 - 41395
full text (doi) - Stripp, S.T., Oltmanns, J., Müller, C.S., Ehrenberg, D., Schlesinger, R., Heberle, J., Adrian, L., Schünemann, V., Pierik, A.J., Soboh, B. (2021):
Electron inventory of the iron-sulfur scaffold complex HypCD essential in [NiFe]-hydrogenase cofactor assembly
Biochem. J. 478 (17), 3281 - 3295
full text (doi) - Trueba-Santiso, A., Wasmund, K., Soder-Walz, J.M., Marco-Urrea, E., Adrian, L. (2021):
Genome sequence, proteome profile, and identification of a multiprotein reductive dehalogenase complex in Dehalogenimonas alkenigignens strain BRE15M
J. Proteome Res. 20 (1), 613 - 623
full text (doi) - Wegner, C.-E., Westermann, M., Steiniger, F., Gorniak, L., Budhraja, R., Adrian, L., Küsel, K. (2021):
Extracellular and intracellular lanthanide accumulation in the methylotrophic Beijerinckiaceae bacterium RH AL1
Appl. Environ. Microb. 87 (13), e03144-20
full text (doi) - Zhang, S., Adrian, L., Schüürmann, G. (2021):
Outer-sphere electron transfer does not underpin B12-dependent olefinic reductive dehalogenation in anaerobes
Phys. Chem. Chem. Phys. 23 (48), 27520 - 27524
full text (doi)
2020 (8)
- Borim Corrêa, F., Eziuzor, S., Peng, S., Schultz, J., Saraiva, J.P., Adrian, L., Stadler, P., Kleinsteuber, S., Vogt, C., Nunes da Rocha, U. (2020):
Genome-resolved metagenomics sheds light on the anaerobic conversion of aromatics by complex communities
3rd Doctoral Colloquium Bioenergy 17/18 September, 2020
DBFZ Deutsches Biomasseforschungszentrum gemeinnützige GmbH, Leipzig, p. 62 - 63
full text (url) - Deobald, D., Hanna, R., Shahryari, S., Layer, G., Adrian, L. (2020):
Identification and characterization of a bacterial core methionine synthase
Sci. Rep. 10 , art. 2100
full text (doi) - Ding, C., Adrian, L. (2020):
Comparative genomics and proteomics in "Candidatus Kuenenia stuttgartiensis" reveal high genomic plasticity in the overall genome structure, CRISPR loci and surface proteins
BMC Genomics 21 , art. 851
full text (doi) - Ding, C., Adrian, L., Peng, Y., He, J. (2020):
16S rRNA gene-based primer pair showed high specificity and quantification accuracy in detecting freshwater Brocadiales anammox bacteria
FEMS Microbiol. Ecol. 96 (3), fiaa013
full text (doi) - Franke, S., Seidel, K., Adrian, L., Nijenhuis, I. (2020):
Dual element (C/Cl) isotope analysis indicates distinct mechanisms of reductive dehalogenation of chlorinated ethenes and dichloroethane in Dehalococcoides mccartyi strain BTF08 with defined reductive dehalogenase inventories
Front. Microbiol. 11 , art. 1507
full text (doi) - Liu, J., Adrian, L., Häggblom, M.M. (2020):
Transcriptomic and proteomic responses of the organohalide-respiring bacterium Desulfoluna spongiiphila to growth with 2,6-dibromophenol as the electron acceptor
Appl. Environ. Microb. 86 (5), e02146-19
full text (doi) - Martínez-Ruiz, E.B., Cooper, M., Al-Zeer, M.A., Kurreck, J., Adrian, L., Szewzyk, U. (2020):
Manganese-oxidizing bacteria form multiple cylindrospermopsin transformation products with reduced human liver cell toxicity
Sci. Total Environ. 729 , art. 138924
full text (doi) - Zhang, S., Adrian, L., Schüürmann, G. (2020):
Dehalococcoides-mediated B12-dependent reductive dehalogenation of aromatics does not proceed through outer-sphere electron transfer
Environ. Sci. Technol. 54 (24), 15751 - 15758
full text (doi)
2019 (7)
- Budhraja, R., Ding, C., Walter, P., Wagner, S., Reemtsma, T., Sawers, G., Adrian, L. (2019):
The impact of species, respiration type, growth phase and genetic inventory on absolute metal content of intact bacterial cells
Metallomics 11 (5), 925 - 935
full text (doi) - Currier, R.B., Ulrich, K., Leroux, A.E., Dirdjaja, N., Deambrosi, M., Bonilla, M., Ahmed, Y.L., Adrian, L., Antelmann, H., Jakob, U., Comini, M.A., Krauth-Siegel, R.L. (2019):
An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone
PLoS Pathog. 15 (9), e1008065
full text (doi) - El-Athman, F., Adrian, L., Jekel, M., Putschew, A. (2019):
Deiodination in the presence of Dehalococcoides mccartyi strain CBDB1: comparison of the native enzyme and co-factor vitamin B12
Environ. Sci. Pollut. Res. 26 (31), 32636 - 32644
full text (doi) - El-Athman, F., Adrian, L., Jekel, M., Putschew, A. (2019):
Abiotic reductive deiodination of iodinated organic compounds and X-ray contrast media catalyzed by free corrinoids
Chemosphere 221 , 212 - 218
full text (doi) - Ongey, E.L., Santolin, L., Waldburger, S., Adrian, L., Riedel, S.L., Neubauer, P. (2019):
Bioprocess development for lantibiotic ruminococcin-A production in Escherichia coli and kinetic insights into LanM enzymes catalysis
Front. Microbiol. 10 , art. 2133
full text (doi) - Ouyang, W.-Y., Su, J.-Q., Richnow, H.H., Adrian, L. (2019):
Identification of dominant sulfamethoxazole-degraders in pig farm-impacted soil by DNA and protein stable isotope probing
Environ. Int. 126 , 118 - 126
full text (doi) - Türkowsky, D., Lohmann, P., Mühlenbrink, M., Schubert, T., Adrian, L., Goris, T., Jehmlich, N., von Bergen, M. (2019):
Thermal proteome profiling allows quantitative assessment of interactions between tetrachloroethene reductive dehalogenase and trichloroethene
J. Proteomics 192 , 10 - 17
full text (doi)
2018 (17)
- Busche, T., Hillion, M., Loi, V.V., Berg, D., Walther, B., Semmler, T., Strommenger, B., Witte, W., Cuny, C., Mellmann, A., Holmes, M.A., Kalinowski, J., Adrian, L., Bernhardt, J., Antelmann, H. (2018):
Comparative secretome analyses of human and zoonotic Staphylococcus aureus isolates CC8, CC22, and CC398
Mol. Cell. Proteomics 17 (12), 2412 - 2433
full text (doi) - Chau, A.T.T., Lee, M., Adrian, L., Manefield, M.J. (2018):
Syntrophic partners enhance growth and respiratory dehalogenation of hexachlorobenzene by Dehalococcoides mccartyi strain CBDB1
Front. Microbiol. 9 , art. 1927
full text (doi) - Chevallier, M.L., Cooper, M., Kümmel, S., Barbance, A., Le Paslier, D., Richnow, H.H., Saaidi, P.-L., Adrian, L. (2018):
Distinct carbon isotope fractionation signatures during biotic and abiotic reductive transformation of chlordecone
Environ. Sci. Technol. 52 (6), 3615 - 3624
full text (doi) - David, C., Schmid, A., Adrian, L., Wilde, A., Bühler, K. (2018):
Production of 1,2-propanediol in photoautotrophic Synechocystis is linked to glycogen turn-over
Biotechnol. Bioeng. 115 (2), 300 - 311
full text (doi) - Deobald, D., Adrian, L., Schöne, C., Rother, M., Layer, G. (2018):
Identification of a unique Radical SAM methyltransferase required for the sp3-C-methylation of an arginine residue of methyl-coenzyme M reductase
Sci. Rep. 8 , art. 7404
full text (doi) - Ding, C., Enyi, F.O., Adrian, L. (2018):
Anaerobic ammonium oxidation (anammox) with planktonic cells in a redox-stable semicontinuous stirred-tank reactor
Environ. Sci. Technol. 52 (10), 5671 - 5681
full text (doi) - Gadkari, J., Goris, T., Schiffmann, C.L., Rubick, R., Adrian, L., Schubert, T., Diekert, G. (2018):
Reductive tetrachloroethene dehalogenation in the presence of oxygen by Sulfurospirillum multivorans: physiological studies and proteome analysis
FEMS Microbiol. Ecol. 94 (1), fix176
full text (doi) - Hawer, H., Ütkür, K., Arend, M., Mayer, K., Adrian, L., Brinkmann, U., Schaffrath, R. (2018):
Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast
PLOS One 13 (10), e0205870
full text (doi) - Imber, M., Huyen, N.T.T., Pietrzyk-Brzezinska, A.J., Loi, V.V., Hillion, M., Bernhardt, J., Thärichen, L., Kolšek, K., Saleh, M., Hamilton, C.J., Adrian, L., Gräter, F., Wahl, M.C., Antelmann, H. (2018):
Protein S-bacillithiolation functions in thiol protection and redox regulation of the glyceraldehyde-3-phosphate dehydrogenase Gap in Staphylococcus aureus under hypochlorite stress
Antioxid. Redox Signal. 28 (6), 410 - 430
full text (doi) - Kruse, S., Goris, T., Westermann, M., Adrian, L., Diekert, G. (2018):
Hydrogen production by Sulfurospirillum species enables syntrophic interactions of Epsilonproteobacteria
Nat. Commun. 9 , art. 4872
full text (doi) - Nowak, K.M., Marco-Urrea, E., Adrian, L. (2018):
Markierung im mikrobiellen Stoffwechsel
Biospektrum 24 (5), 491 - 494
full text (doi) - Ongey, E.L., Giessmann, R.T., Fons, M., Rappsilber, J., Adrian, L., Neubauer, P. (2018):
Heterologous biosynthesis, modifications and structural characterization of ruminococcin-A, a lanthipeptide from the gut bacterium Ruminococcus gnavus E1, in Escherichia coli
Front. Microbiol. 9 , art. 1688
full text (doi) - Schubert, T., Adrian, L., Sawers, R.G., Diekert, G. (2018):
Organohalide respiratory chains: composition, topology and key enzymes
FEMS Microbiol. Ecol. 94 (4), fiy035
full text (doi) - Seidel, K., Kühnert, J., Adrian, L. (2018):
The complexome of Dehalococcoides mccartyi reveals its organohalide respiration-complex is modular
Front. Microbiol. 9 , art. 1130
full text (doi) - Shahryari, S., Zahiri, H.S., Haghbeen, K., Adrian, L., Noghabi, K.A. (2018):
High phenol degradation capacity of a newly characterized Acinetobacter sp. SA01: Bacterial cell viability and membrane impairment in respect to the phenol toxicity
Ecotox. Environ. Safe. 164 , 455 - 466
full text (doi) - Türkowsky, D., Jehmlich, N., Diekert, G., Adrian, L., von Bergen, M., Goris, T. (2018):
An integrative overview of genomic, transcriptomic and proteomic analyses in organohalide respiration research
FEMS Microbiol. Ecol. 94 (3), fiy013
full text (doi) - Zhang, S., Adrian, L., Schüürmann, G. (2018):
Interaction mode and regioselectivity in vitamin B12-dependent dehalogenation of aryl halides by Dehalococcoides mccartyi strain CBDB1
Environ. Sci. Technol. 52 (4), 1834 - 1843
full text (doi)
2017 (5)
- Frauenstein, D., Seidel, K., Adrian, L. (2017):
SandTraps are efficient, scalable, and mild systems for harvesting, washing and concentrating cells
J. Microbiol. Methods 132 , 106 - 111
full text (doi) - Hartwig, S., Dragomirova, N., Kublik, A., Türkowsky, D., von Bergen, M., Lechner, U., Adrian, L., Sawers, R.G. (2017):
A H2-oxidizing, 1,2,3-trichlorobenzene-reducing multienzyme complex isolated from the obligately organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1
Environ. Microbiol. Rep. 9 (5), 618 - 625
full text (doi) - Hillion, M., Imber, M., Pedre, B., Bernhardt, J., Saleh, M., Loi, V.V., Maaß, S., Becher, D., Rosado, L.A., Adrian, L., Weise, C., Hell, R., Wirtz, M., Messens, J., Antelmann, H. (2017):
The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress
Sci. Rep. 7 , art. 5020
full text (doi) - Mortan, S.H., Martín-González, L., Vicent, T., Caminal, G., Nijenhuis, I., Adrian, L., Marco-Urrea, E. (2017):
Detoxification of 1,1,2-trichloroethane to ethene in a bioreactor co-culture of Dehalogenimonas and Dehalococcoides mccartyi strains
J. Hazard. Mater. 331 , 218 - 225
full text (doi) - Zhang, S., Wondrousch, D., Cooper, M., Zinder, S.H., Schüürmann, G., Adrian, L. (2017):
Anaerobic dehalogenation of chloroanilines by Dehalococcoides mccartyi strain CBDB1 and Dehalobacter strain 14DCB1 via different pathways as related to molecular electronic structure
Environ. Sci. Technol. 51 (7), 3714 - 3724
full text (doi)
2016 (14)
- Adrian, L., Löffler, F.E. (eds., 2016):
Organohalide-respiring bacteria
Springer, Berlin, Heidelberg, VII, 632 pp.
full text (doi) - Adrian, L., Löffler, F.E. (2016):
Outlook—the next frontiers for research on organohalide-respiring bacteria
In: Adrian, L., Löffler, F.E. (eds.)
Organohalide-respiring bacteria
Springer, Berlin, Heidelberg, p. 621 - 627
full text (doi) - Adrian, L., Löffler, F.E. (2016):
Organohalide-respiring bacteria—an introduction
In: Adrian, L., Löffler, F.E. (eds.)
Organohalide-respiring bacteria
Springer, Berlin, Heidelberg, p. 3 - 6
full text (doi) - Adrian, L., Marco-Urrea, E. (2016):
Isotopes in geobiochemistry: tracing metabolic pathways in microorganisms of environmental relevance with stable isotopes
Curr. Opin. Biotechnol. 41 , 19 - 25
full text (doi) - Biderre-Petit, C., Dugat-Bony, E., Mege, M., Parisot, N., Adrian, L., Moné, A., Denonfoux, J., Peyretaillade, E., Debroas, D., Boucher, D., Peyret, P. (2016):
Distribution of Dehalococcoidia in the anaerobic deep water of a remote meromictic crater lake and detection of Dehalococcoidia-derived reductive dehalogenase homologous genes
PLOS One 11 (1), e0145558
full text (doi) - Goris, T., Schiffmann, C.L., Gadkari, J., Adrian, L., von Bergen, M., Diekert, G., Jehmlich, N. (2016):
Proteomic data set of the organohalide-respiring Epsilonproteobacterium Sulfurospirillum multivorans adapted to tetrachloroethene and other energy substrates
Data Brief 8 , 637 - 642
full text (doi) - Krasper, L., Lilie, H., Kublik, A., Adrian, L., Golbik, R., Lechner, U. (2016):
The MarR-type regulator Rdh2R regulates rdh gene transcription in Dehalococcoides mccartyi strain CBDB1
J. Bacteriol. 198 (23), 3130 - 3141
full text (doi) - Kublik, A., Deobald, D., Hartwig, S., Schiffmann, C.L., Andrades, A., von Bergen, M., Sawers, R.G., Adrian, L. (2016):
Identification of a multi-protein reductive dehalogenase complex in Dehalococcoides mccartyi strain CBDB1 suggests a protein-dependent respiratory electron transport chain obviating quinone involvement
Environ. Microbiol. 18 (9), 3044 - 3056
full text (doi) - Laso-Pérez, R., Wegener, G., Knittel, K., Widdel, F., Harding, K.J., Krukenberg, V., Meier, D.V., Richter, M., Tegetmeyer, H.E., Riedel, D., Richnow, H.-H., Adrian, L., Reemtsma, T., Lechtenfeld, O.J., Musat, F. (2016):
Thermophilic archaea activate butane via alkyl-coenzyme M formation
Nature 539 (7629), 396 - 401
full text (doi) - Lünsmann, V., Kappelmeyer, U., Benndorf, R., Martínez-Lavanchy, P.M., Taubert, A., Adrian, L., Duarte, M., Pieper, D.H., von Bergen, M., Müller, J.A., Heipieper, H.J., Jehmlich, N. (2016):
In situ protein-SIP highlights Burkholderiaceae as key players degrading toluene by para ring hydroxylation in a constructed wetland model
Environ. Microbiol. 18 (4), 1176 - 1186
full text (doi) - Schiffmann, C.L., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen, M., Jehmlich, N. (2016):
Proteomic dataset of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
Data Brief 7 , 253 - 256
full text (doi) - Schubert, T., Adrian, L., Diekert, G. (2016):
Organohalid-Atmung bei Mikroorganismen. Anaerober Energiestoffwechsel
Biospektrum 22 (5), 462 - 464
full text (doi) - Tiedt, O., Mergelsberg, M., Boll, K., Müller, M., Adrian, L., Jehmlich, N., von Bergen, M., Boll, M. (2016):
ATP-dependent C–F bond cleavage allows the complete degradation of 4-fluoroaromatics without oxygen
mBio 7 (4), e00990-16
full text (doi) - Wasmund, K., Cooper, M., Schreiber, L., Lloyd, K.G., Baker, B.J., Petersen, D.G., Jørgensen, B.B., Stepanauskas, R., Reinhardt, R., Schramm, A., Loy, A., Adrian, L. (2016):
Single-cell genome and group-specific dsrAB sequencing implicate marine members of the class Dehalococcoidia (phylum Chloroflexi) in sulfur cycling
mBio 7 (3), e00266-16
full text (doi)
2015 (7)
- Algora, C., Vasileiadis, S., Wasmund, K., Trevisan, M., Krüger, M., Puglisi, E., Adrian, L. (2015):
Manganese and iron as structuring parameters of microbial communities in Arctic marine sediments from the Baffin Bay
FEMS Microbiol. Ecol. 91 (6), fiv056
full text (doi) - Cooper, M., Wagner, A., Wondrousch, D., Sonntag, F., Sonnabend, A., Brehm, M., Schüürmann, G., Adrian, L. (2015):
Anaerobic microbial transformation of halogenated aromatics and fate prediction using electron density modeling
Environ. Sci. Technol. 49 (10), 6018 - 6028
full text (doi) - Hartwig, S., Thomas, C., Krumova, N., Quitzke, V., Türkowsky, D., Jehmlich, N., Adrian, L., Sawers, R.G. (2015):
Heterologous complementation studies in Escherichia coli with the Hyp accessory protein machinery from Chloroflexi provide insight into [NiFe]-hydrogenase large subunit recognition by the HypC protein family
Microbiology-(UK) 161 (11), 2204 - 2219
full text (doi) - Lee, M., Wells, E., Wong, Y.K., Koenig, J., Adrian, L., Richnow, H.H., Manefield, M. (2015):
Relative contributions of Dehalobacter and zerovalent iron in the degradation of chlorinated methanes
Environ. Sci. Technol. 49 (7), 4481 - 4489
full text (doi) - Martín-González, L., Hatijah Mortan, S., Rosell, M., Parladé, E., Martínez-Alonso, M., Gaju, N., Caminal, G., Adrian, L., Marco-Urrea, E. (2015):
Stable carbon isotope fractionation during 1,2-dichloropropane-to-propene transformation by an enrichment culture containing Dehalogenimonas strains and a dcpA gene
Environ. Sci. Technol. 49 (14), 8666 - 8674
full text (doi) - Wasmund, K., Algora, C., Müller, J., Krüger, M., Lloyd, K.G., Reinhardt, R., Adrian, L. (2015):
Development and application of primers for the class Dehalococcoidia (phylum Chloroflexi) enables deep insights into diversity and stratification of sub-groups in the marine subsurface
Environ. Microbiol. 17 (10), 3540 - 3556
full text (doi) - Yang, C., Kublik, A., Weidauer, C., Seiwert, B., Adrian, L. (2015):
Reductive dehalogenation of oligocyclic phenolic bromoaromatics by Dehalococcoides mccartyi strain CBDB1
Environ. Sci. Technol. 49 (14), 8497– - 8505
full text (doi)
2014 (5)
- Goris, T., Schubert, T., Gadkari, J., Wubet, T., Tarkka, M., Buscot, F., Adrian, L., Diekert, G. (2014):
Insights into organohalide respiration and the versatile catabolism of Sulfurospirillum multivorans gained from comparative genomics and physiological studies
Environ. Microbiol. 16 (11), 3562 - 3580
full text (doi) - Musat, N., Stryhanyuk, H., Bombach, P., Adrian, L., Audinot, J.-N., Richnow, H.H. (2014):
The effect of FISH and CARD-FISH on the isotopic composition of 13C- and 15N-labeled Pseudomonas putida cells measured by nanoSIMS
Syst. Appl. Microbiol. 37 (4), 267 - 276
full text (doi) - Schiffmann, C., Hansen, R., Baumann, S., Kublik, A., Nielsen, P.H., Adrian, L., von Bergen, M., Jehmlich, N., Seifert, J. (2014):
Comparison of targeted peptide quantification assays for reductive dehalogenases by selective reaction monitoring (SRM) and precursor reaction monitoring (PRM)
Anal. Bioanal. Chem. 406 (1), 283 - 291
full text (doi) - Schiffmann, C.L., Jehmlich, N., Otto, W., Hansen, R., Nielsen, P.H., Adrian, L., Seifert, J., von Bergen-Tomm, M. (2014):
Proteome profile and proteogenomics of the organohalide-respiring bacterium Dehalococcoides mccartyi strain CBDB1 grown on hexachlorobenzene as electron acceptor
J. Proteomics 98 , 59 - 64
full text (doi) - Wasmund, K., Schreiber, L., Lloyd, K.G., Petersen, D.G., Schramm, A., Stepanauskas, R., Jørgensen, B.B., Adrian, L. (2014):
Genome sequencing of a single cell of the widely distributed marine subsurface Dehalococcoidia, phylum Chloroflexi
ISME J. 8 (2), 383 - 397
full text (doi)
2013 (9)
- Algora, C., Gründger, F., Adrian, L., Damm, V., Richnow, H.-H., Krüger, M. (2013):
Geochemistry and microbial populations in sediments of the Northern Baffin Bay, Arctic
Geomicrobiol. J. 30 (8), 690 - 705
full text (doi) - Duan, T.H., Adrian, L. (2013):
Enrichment of hexachlorobenzene and 1,3,5-trichlorobenzene transforming bacteria from sediments in Germany and Vietnam
Biodegradation 24 (4), 513 - 520
full text (doi) - Hug, L.A., Maphosa, F., Leys, D., Löffler, F.E., Smidt, H., Edwards, E.A., Adrian, L. (2013):
Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases
Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), art. 20120322
full text (doi) - Leys, D., Adrian, L., Smidt, H. (2013):
Organohalide respiration: microbes breathing chlorinated molecules
Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), 20120316
full text (doi) - Löffler, F.E., Yan, J., Ritalahti, K.M., Adrian, L., Edwards, E.A., Konstantinidis, K.T., Müller, J.A., Fullerton, H., Zinder, S.H., Spormann, A.M. (2013):
Dehalococcoides mccartyi gen. nov., sp. nov., obligately organohalide-respiring anaerobic bacteria relevant to halogen cycling and bioremediation, belong to a novel bacterial class, Dehalococcoidia classis nov., order Dehalococcoidales ord. nov. and family Dehalococcoidaceae fam. nov., within the phylum Chloroflexi
Int. J. Syst. Evol. Microbiol. 63 (2), 625 - 635
full text (doi) - Pöritz, M., Goris, T., Wubet, T., Tarkka, M.T., Buscot, F., Nijenhuis, I., Lechner, U., Adrian, L. (2013):
Genome sequences of two dehalogenation specialists - Dehalococcoides mccartyi strains BTF08 and DCMB5 enriched from the highly polluted Bitterfeld region
FEMS Microbiol. Lett. 343 (2), 101 - 104
full text (doi) - Puglisi, E., Trevisan, M., Grotenhuis, T., Adrian, L. (2013):
EUROSOIL 2012 bioremediation session: preface to special issue
Biodegradation 24 (4), 451 - 453
full text (doi) - Schipp, C.-J., Marco-Urrea, E., Kublik, A., Seifert, J., Adrian, L. (2013):
Organic cofactors in the metabolism of Dehalococcoides mccartyi strains
Philos. Trans. R. Soc. B-Biol. Sci. 368 (1616), 20120321
full text (doi) - Tang, S., Chan, W.W.M., Fletcher, K.E., Seifert, J., Liang, X., Löffler, F.E., Edwards, E.A., Adrian, L. (2013):
Functional characterization of reductive dehalogenases using blue native polyacrylamide gel electrophoresis
Appl. Environ. Microb. 79 (3), 974 - 981
full text (doi)
2012 (4)
- Adrian, L., Vogt, C., Richnow, H.-H. (2012):
Geochemical processes contributing to electrical currents in microbial fuel cells
1st UFZ Energy Days 2012: 4-5 April 2012 ; book of abstracts
UFZ-Bericht 6/2012
Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, p. 53 - Kadirova, G.K., Andreevich, K.A., Adrian, L., Bakhtiyor, R. (2012):
Functioning of salt tolerant Anabaena variabilis and Nostoc calcicola strains in salt stress, destructors of hexachlorocyclohexane (HCH) in saline conditions
Environment and Natural Resources Research 2 (1), 63 - 72
full text (doi) - Marco-Urrea, E., Seifert, J., von Bergen, M., Adrian, L. (2012):
Stable isotope peptide mass spectrometry to decipher amino acid metabolism in Dehalococcoides strain CBDB1
J. Bacteriol. 194 (16), 4169 - 4177
full text (doi) - Wagner, A., Cooper, M., Ferdi, S., Seifert, J., Adrian, L. (2012):
Growth of Dehalococcoides mccartyi strain CBDB1 by reductive dehalogenation of brominated benzenes to benzene
Environ. Sci. Technol. 46 (16), 8960 - 8968
full text (doi)
2011 (3)
- Marco-Urrea, E., Nijenhuis, I., Adrian, L. (2011):
Transformation and carbon isotope fractionation of tetra- and trichloroethene to Trans-Dichloroethene by Dehalococcoides sp. strain CBDB1
Environ. Sci. Technol. 45 (4), 1555 - 1562
full text (doi) - Marco-Urrea, E., Paul, S., Khodaverdi, V., Seifert, J., von Bergen, M., Kretzschmar, U., Adrian, L. (2011):
Identification and characterization of a Re-Citrate synthase in Dehalococcoides strain CBDB1
J. Bacteriol. 193 (19), 5171 - 5178
full text (doi) - Prieto, A., Möder, M., Rodil, R., Adrian, L., Marco-Urrea, E. (2011):
Degradation of the antibiotics norfloxacin and ciprofloxacin by a white-rot fungus and identification of degradation products
Bioresour. Technol. 102 (23), 10987 - 10995
full text (doi)
2010 (4)
- Hölscher, T., Breuer, U., Adrian, L., Harms, H., Maskow, T. (2010):
Production of the chiral compound (R)-3-Hydroxybutyrate by a genetically engineered methylotrophic bacterium
Appl. Environ. Microb. 76 (16), 5585 - 5591
full text (doi) - Hölscher, T., Lisec, J., Baani, M., Duan, T.H., Adrian, L. (2010):
Bacterial cultures preferentially removing singly flanked chlorine substituents from chlorobenzenes
Environ. Sci. Technol. 44 (23), 8936 - 8942
full text (doi) - Kretzschmar, U., Khodaverdi, V., Adrian, L. (2010):
Transcriptional regulation of the acetyl-CoA synthetase gene acsA in Pseudomonas aeruginosa
Arch. Microbiol. 192 (8), 685 - 690
full text (doi) - Rasulov, B.A., Kim, A.A., Adrian, L., Yadgarov, K.T. (2010):
Biodegradation of tritium labeled polychlorinated biphenyls (PCBs)by local salt tolerant mesophylic bacillus strains
Journal of Environmental Protection 1 (4), 420 - 425
full text (doi)
2009 (4)
- Adrian, L. (2009):
ERC-group microflex: microbiology of Dehalococcoides-like Chloroflexi
Reviews in Environmental Science and Biotechnology 8 (3), 225 - 229
full text (doi) - Adrian, L., Dudková, V., Demnerová, K., Bedard, D.L. (2009):
"Dehalococcoides" sp. strain CBDB1 extensively dechlorinates the commercial polychlorinated biphenyl mixture aroclor 1260
Appl. Environ. Microb. 75 (13), 4516 - 4524
full text (doi) - Adrian, L., Reinhardt, R., Kube, M. (2009):
Genomics as a tool to analyze bioremediation potentials and functional diversification in subsurface environments
Geochim. Cosmochim. Acta 73 (13 Suppl.), A12
full text (doi) - Wagner, A., Adrian, L., Kleinsteuber, S., Andreesen, J.R., Lechner, U. (2009):
Transcription analysis of genes encoding homologues of reductive dehalogenases in "Dehalococcoides" sp. strain CBDB1 by using terminal restriction fragment length polymorphism and quantitative PCR
Appl. Environ. Microb. 75 (7), 1876 - 1884
full text (doi)
2007 (3)
- Adrian, L., Hansen, S.K., Fung, J.M., Gorisch, H., Zinder, S.H. (2007):
Growth of Dehalococcoides strains with chlorophenols as electron acceptors
Environ. Sci. Technol. 41 (7), 2318 - 2323
full text (doi) - Adrian, L., Rahnenführer, J., Gobom, J., Hölscher, T. (2007):
Identification of a chlorobenzene reductive dehalogenase in Dehalococcoides sp. strain CBDB1
Appl. Environ. Microb. 73 (23), 7717 - 7724
full text (doi) - Fung, J.M., Morris, R.M., Adrian, L., Zinder, S.H. (2007):
Expression of reductive dehalogenase genes in Dehalococcoides ethenogenes strain 195 growing on tetrachloroethene, trichloroethene, or 2,3-dichlorophenol
Appl. Environ. Microb. 73 (14), 4439 - 4445
full text (doi)
2005 (2)
- Kube, M., Beck, A., Zinder, S.H., Kuhl, H., Reinhardt, R., Adrian, L. (2005):
Genome sequence of the chlorinated compound respiring bacterium Dehalococcoides species strain CBDB1
Nat. Biotechnol. 23 (10), 1269 - 1273
full text (doi) - Seshadri, R., Adrian, L., Fouts, D.E., Eisen, J.A., Phillippy, A.M., Methe, B.A., Ward, N.L., Nelson, W.C., Deboy, R.T., Khouri, H.M., Kolonay, J.F., Dodson, R.J., Daugherty, S.C., Brinkac, L.M., Sullivan, S.A., Madupu, R., Nelson, K.T., Kang, K.H., Impraim, M., Tran, K., Robinson, J.M., Forberger, H.A., Fraser, C.M., Zinder, S.H., Heidelberg, J.F. (2005):
Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes
Science 307 (5706), 105 - 108
full text (doi)
2004 (7)
- Adrian, L., Lechner, U. (2004):
Anaerobic transformation of chlorinated dioxins by microorganisms
Organohalogen Compounds 66 , 2241 - 2246
full text (url) - Adrian, L., Lechner, U. (2004):
Reductive dehalogenation of polychlorinated benzenes and dioxins
In: Nakano, M.M., Zuber, P. (eds.)
Strict and facultative anaerobes: medical and environmental aspects
Horizon Bioscience, Wymondham, Norfolk, p. 303 - 316 - Griebler, C., Adrian, L., Meckenstock, R.U., Richnow, H.H. (2004):
Stable carbon isotope fractionation during aerobic and anaerobic transformation of trichlorobenzene
FEMS Microbiol. Ecol. 48 (3), 313 - 321
full text (doi) - Hölscher, T., Krajmalnik-Brown, R., Ritalahti, K.M., von Wintzingerode, F., Gorisch, H., Löffler, F.E., Adrian, L. (2004):
Multiple nonidentical reductive-dehalogenase-homologous genes are common in Dehalococcoides
Appl. Environ. Microb. 70 (9), 5290 - 5297
full text (doi) - Jayachandran, G., Görisch, H., Adrian, L. (2004):
Studies on hydrogenase activity and chlorobenzene respiration in Dehalococcoides sp. strain CBDB1
Arch. Microbiol. 182 (6), 498 - 504
full text (doi) - Lechner, U., Bunge, M., Adrian, L. (2004):
Reduktive Dehalogenierung von chlorierten Benzolen und Dioxinen durch Dehalococcoides
Biospektrum 10 (5), 630 - 632
full text (url) - Rosenthal, H., Adrian, L., Steiof, M. (2004):
Dechlorination of PCE in the presence of Fe0 enhanced by a mixed culture containing two Dehalococcoides strains
Chemosphere 55 (5), 661 - 669
full text (doi)
2003 (5)
- Bunge, M., Adrian, L., Kraus, A., Opel, M., Lorenz, W.G., Andreesen, J.R., Görisch, H., Lechner, U. (2003):
Reductive dehalogenation of chlorinated dioxins by an anaerobic bacterium
Nature 421 (6921), 357 - 360
full text (doi) - Hölscher, T., Görisch, H., Adrian, L. (2003):
Reductive dehalogenation of chlorobenzene congeners in cell extracts of Dehalococcoides sp. strain CBDB1
Appl. Environ. Microb. 69 (5), 2999 - 3001
full text (doi) - Jayachandran, G., Görisch, H., Adrian, L. (2003):
Dehalorespiration with hexachlorobenzene and pentachlorobenzene by Dehalococcoides sp. strain CBDB1
Arch. Microbiol. 180 (6), 411 - 416
full text (doi) - Meyer, B.C., Jacksche, J., Adrian, L. (2003):
Indicators for landscape sustainability of farms
In: Mander, U., Antrop, M. (eds.)
Multifunctional landscapes. Volume III: Continuity and change
Advances in Ecological Sciences 16
WIT Press, Southampton, p. 79 - 94 - Moreno Horn, M., Garbe, L.-A., Tressl, R., Adrian, L., Görisch, H. (2003):
Biodegradation of bis(1-chloro-2-propyl) ether via initial ether scission and subsequent dehalogenation by Rhodococcus sp. strain DTB
Arch. Microbiol. 179 (4), 234 - 241
full text (doi)
2002 (2)
- Adrian, L., Görisch, H. (2002):
Microbial transformation of chlorinated benzenes under anaerobic conditions
Res. Microbiol. 153 (3), 131 - 137
full text (doi) - Adrian, L., Görisch, H. (2002):
Transformation chlororganischer Verbindungen durch Dehalococcoides-Species
BIOforum 25 (5), 2 - 3
2001 (2)
- Hauck, R., Adrian, L., Wendler, P., Amidjojo, M., Hegemann, W., Görisch, H. (2001):
Transformation of 2,2'-dichlorodiisopropyl ether in mixed and pure culture
Appl. Microbiol. Biotechnol. 56 (3-4), 491 - 495
full text (doi) - Yoo, E.S., Libra, J., Adrian, L. (2001):
Mechanism of decolorization of azo dyes in anaerobic mixed culture
J. Environ. Eng.-ASCE 127 (9), 844 - 849
full text (doi)
2000 (2)
- Adrian, L., Szewzyk, U., Görisch, H. (2000):
Bacterial growth based on reductive dechlorination of trichlorobenzenes
Biodegradation 11 (1), 73 - 81
full text (doi) - Adrian, L., Szewzyk, U., Wecke, J., Görisch, H. (2000):
Bacterial dehalorespiration with chlorinated benzenes
Nature 408 (6812), 580 - 583
full text (doi)
1998 (1)
- Adrian, L., Manz, W., Szewzyk, U., Görisch, H. (1998):
Physiological characterization of a bacterial consortium reductively dechlorinating 1,2,3- and 1,2,4-trichlorobenzene
Appl. Environ. Microb. 64 (2), 496 - 503