Dr. Chang Ding
|2015-2018||Postdoc Humboldt Research Fellowship, UFZ|
|2014-2015||Research fellow, National University of Singapore, Singapore|
Ph.D., Department of Civil and Environmental Engineering, National University of Singapore, Singapore
Thesis title: Isolation and characterization of novel bacterial strains that detoxify polybrominated diphenyl ethers and chlorinated alkanes
Advisor: Associate Professor Dr. Jianzhong He
|2008||Bachelor of Engineering, Department of Environmental Science and Engineering (now School of Environment), Tsinghua University, Beijing, China|
My research focuses on anaerobic/anoxic microbial processes, e.g., anaerobic ammonium oxidation (anammox) and organohalide respiration. The aim is to understand the mechanisms controlling the behaviors of the responsible microorganisms and their interaction with the environment. Techniques involved include anaerobic cultivation, physiological characterization, biochemical assays, proteomics. Several high customized continuous reactors cultivating planktonic anammox bacteria are in operation since 2016.
- Zhao S., Ding C., Xu G., Rogers M. J. Ramaswamy R., He J. (2022):
Diversity of organohalide respiring bacteria and reductive dehalogenases that detoxify polybrominated diphenyl ethers in E-waste recycling sites.
The ISME Journal. DOI: 10.1038/s41396-022-01257-0
- Zhao S., Rogers M., Cao L., Ding C., & He J. (2021):
Identification of reductive dehalogenases that mediate complete debromination of penta- and tetrabrominated diphenyl ethers in Dehalococcoides spp.
Applied and Environmental Microbiology. 87 (17), e00602-21
- Budhraja R., Karande S., Ding C., Ullrich M.K., Wagner S., Reemtsma T., & Adrian L. (2021):
Characterization of membrane-bound metalloproteins in the anaerobic ammonium-oxidizing bacterium “Candidatus Kuenenia stuttgartiensis” strain CSTR1.
Talanta. 223, 121711
- Ding C.*, & Adrian L. (2020):
Comparative genomics in “Candidatus Kuenenia stuttgartiensis” reveal high genomic plasticity in the overall genome structure, CRISPR loci and surface proteins.
BMC Genomics. 21, 851
- Ding C., Rogers M. J., & He J. (2020):
Dehalococcoides mccartyi strain GEO12 has a natural tolerance to chloroform inhibition.
Environmental Science & Technology. 54 (14), 8750–8759
- Ding C.*, Adrian L., Peng Y., & He J.* (2020):
16S rRNA gene-based primer pair showed high specificity and quantification accuracy in detecting freshwater Brocadiales anammox bacteria.
FEMS Microbiology Ecology. 96 (3), fiaa013
- Budhraja R., Ding C., Walter P., Wagner S., Reemtsma T., Sawers, G. R., & Adrian L. (2019):
The impact of species, respiration type, growth phase and genetic inventory on absolute metal content of intact bacterial cells.
Metallomics, 11, 925-935
- Ding C.*, Enyi F. O., & Adrian L., (2018):
Anaerobic ammonium oxidation (anammox) with planktonic cells in a redox-stable semicontinuous stirred-tank reactor
Environmental Science & Technology. 52 (10), 5671-5681.
- Ding C., Alvarez-Cohen L., & He J. (2018):
Growth of Dehalococcoides mccartyi species in an autotrophic consortium producing limited acetate.
Biodegradation, 29(5), 487-498.
- Zhao S., Rogers M.J., Ding C., & He J. (2018):
Reductive debromination of polybrominated diphenyl ethers - microbes, pathways and dehalogenase.
Frontiers in Microbiology. 9, 1292.
- Wang Q., Ding C., Tao G., & He J. (2018):
Analysis of enhanced nitrogen removal mechanisms in a validation wastewater treatment plant containing anammox bacteria.
Applied Microbiology and Biotechnology, 103, 1255–1265
- Ding C., Rogers M.J., Yang K.-L., & He J. (2017):
Loss of the ssrA genome island led to partial debromination in the PBDE respiring Dehalococcoides mccartyi strain GY50
Environmental Microbiology. 19 (7), 2906 - 2915
- Zhao S., Ding C., & He J. (2017):
Genomic characterization of Dehalococcoides mccartyi strain 11a5 reveals a circular extrachromosomal genetic element and a new tetrachloroethene reductive dehalogenase gene
FEMS Microbiology Ecology. 93 (4), fiw235
- Ding C., Yang K.-L., & He J. (2016):
Biological and fermentative production of hydrogen
In: Luque, R., Lin, C.S.K., Wilson, K., Clark, J., (eds.)
Handbook of biofuels production: processes and technologies (Second edition)
Woodhead Publishing series in energy 98
Woodhead Publishing, Cambridge, p. 303 - 333
- Zhao S., Ding C., & He J. (2015):
Detoxification of 1,1,2-trichloroethane to ethene by Desulfitobacterium and identification of its functional reductase gene
PLoS ONE 10 (4), e0119507
- Ding C., Zhao S., & He J. (2014):
A Desulfitobacterium sp. strain PR reductively dechlorinates both 1,1,1-trichloroethane and chloroform
Environmental Microbiology. 16 (11), 3387-3397
- Ding C., Chow W. L., & He J. (2013):
Isolation of Acetobacterium sp. strain AG that reductively debrominates octa- and penta- brominated diphenyl ether technical mixtures
Applied and Environmental Microbiology. 79 (4), 1110-1117
- Ding C., & He J. (2012):
Molecular techniques in the biotechnological fight against halogenated compounds in anoxic environments
Microbial Biotechnology 5 (3), 347-367
- Lee L. K., Ding C., Yang K. L., & He J. (2011):
Complete debromination of tetra- and penta- brominated diphenyl ethers by a coculture consisting of Dehalococcoides and Desulfovibrio species
Environmental Science & Technology. 45 (19), 8475-8482
- Ning D., Wang H., Ding C., & Lu H. (2010):
Novel evidence of cytochrome P450-catalyzed oxidation of phenanthrene in Phanerochaete chrysosporium under ligninolytic conditions
Biodegradation. 21 (6), 889-901
- Ding C., & He J. (2010):
Effect of antibiotics in the environment on microbial populations
Applied Microbiology and Biotechnology. 87 (3), 925-941