Katja Seidel
Phone Office +49 (0) 341 235 1412
Phone Lab +49 (0) 341 235 1549
Curriculum Vitae
2014 - | PhD student UFZ |
2012 - 2014 | Master of Science Biochemistry, Martin-Luther University Halle-Wittenberg |
2009 - 2012 | Bachelor of Science Biochemistry, Martin-Luther University Halle-Wittenberg |
Research
My research focusses on the respiratory multienzyme complex in Dehalococcoides mccartyi strain CBDB1. This complex is of special interest as it seems to be enough to transfer electrons from donor to acceptor in a protein-bound manner avoiding electron shuttles as quinones and cytchromes. My interest is to purify this complex and retain activity afterwards, to characterize the reductive dehalogenase and its anchoring protein in more detail with cross-linking experiments, gel-based methodes and activity assays combined with mass spectrometric analyes.
Furthermore I investigate the entirety of membrane complexes in strain CBDB1 with separation on Blue-Native PAGE and mass spectrometryi analyses, also kown as complexome analysis.
Publications
2020 (1)
- Franke, S., Seidel, K., Adrian, L., Nijenhuis, I. (2020):
Dual element (C/Cl) isotope analysis indicates distinct mechanisms of reductive dehalogenation of chlorinated ethenes and dichloroethane in Dehalococcoides mccartyi strain BTF08 with defined reductive dehalogenase inventories
Front. Microbiol. 11 , art. 1507 10.3389/fmicb.2020.01507
2018 (1)
- Seidel, K., Kühnert, J., Adrian, L. (2018):
The complexome of Dehalococcoides mccartyi reveals its organohalide respiration-complex is modular
Front. Microbiol. 9 , art. 1130 10.3389/fmicb.2018.01130
2017 (1)
- Frauenstein, D., Seidel, K., Adrian, L. (2017):
SandTraps are efficient, scalable, and mild systems for harvesting, washing and concentrating cells
J. Microbiol. Methods 132 , 106 - 111 10.1016/j.mimet.2016.11.018