2023 (1)

• Wilhelmi, P., Giri, V., Zickgraf, F.M., Haake, V., Henkes, S., Driemert, P., Michaelis, P., Busch, W., Scholz, S., Flick, B., Barenys, M., Birk, B., Kamp, H., Landsiedel, R., Funk-Weyer, D. (2023):
  A metabolomics approach to reveal the mechanism of developmental toxicity in zebrafish embryos exposed to 6-propyl-2-thiouracil
  Chem.-Biol. Interact.
  full text (doi)

2022 (4)

• Finckh, S., Beckers, L.-M., Busch, W., Carmona, E., Dulio, V., Kramer, L., Krauss, M., Posthuma, L., Schulze, T., Slootweg, J., von der Ohe, P.C., Brack, W. (2022):
  A risk based assessment approach for chemical mixtures from wastewater treatment plant effluents
  Environ. Int. 164 , art. 107234
  full text (doi)
• Nöth, J., Michaelis, P., Busch, W., Scholz, S. (2022):
  Analysis vascular disruptors in zebrafish embryos as an endpoint to predict developmental toxicity
  Toxicol. Lett. 368 (Suppl.), S34 - S35
  full text (doi)
• Schor, J., Scheibe, P., Bernt, M., Busch, W., Lai, C., Hackermüller, J. (2022):
  AI for predicting chemical-effect associations at the chemical universe level — deepFPlearn
  Brief. Bioinform. 23 (5), bbac257
  full text (doi)
• Wilhelmi, P., Giri, V., Henkes, S., Walk, T., Haake, V., Scholz, S., Busch, W., Barenys, M., Zickgraf, F., Landsiedel, R., Funk-Weyer, D., Birk, B., Flick, B. (2022):
  A targeted metabolomics approach for unraveling different modes of embryotoxicity in zebrafish
  Toxicol. Lett. 368 (Suppl.), S252 - S252
  full text (doi)

2021 (2)

• Schüttler, A., Jakobs, G., Fix, J.M., Krauss, M., Krüger, J., Leuthold, D., Altenburger, R., Busch, W. (2021):
  Transcriptome-wide prediction and measurement of combined effects induced by chemical mixture exposure in zebrafish embryos
  Environ. Health Perspect. 129 (4), art. 047006
  full text (doi)
• Weitere, M., Altenburger, R., Anlanger, C., Baborowski, M., Bärlund, I., Beckers, L.-M., Borchardt, D., Brack, W., Brase, L., Busch, W., Chatzinotas, A., Deutschmann, B., Eligehausen, J., Frank, K., Graeber, D., Griebler, C., Hagemann, J., Herzsprung, P., Hollert, H., Inostroza, P.A., Jäger, C.G., Kallies, R., Kamjunke, N., Karrasch, B., Kaschuba, S., Kaus, A., Klauer, B., Knöller, K., Koschorreck, M., Krauss, M., Kunz, J.V., Kurz, M.J., Liess, M., Mages, M., Müller, C., Muschket, M., Musolff, A., Norf, H., Pöhlein, F., Reiber, L., Risse-Buhl, U., Schramm, K.-W., Schmitt-Jansen, M., Schmitz, M., Strachauer, U., von Tümpling, W., Weber, N., Wild, R., Wolf, C., Brauns, M. (2021):
  Disentangling multiple chemical and non-chemical stressors in a lotic ecosystem using a longitudinal approach
  Sci. Total Environ. 769 , art. 144324
  full text (doi)

2020 (4)

• Canzler, S., Schor, J., Busch, W., Schubert, K., Rolle-Kampczyk, U.E., Seitz, H., Kamp, H., von Bergen, M., Buesen, R., Hackermüller, J. (2020):
  Prospects and challenges of multi‑omics data integration in toxicology
  Arch. Toxicol. 94 (2), 371 - 388
  full text (doi)
• Jakobs, G., Krüger, J., Schüttler, A., Altenburger, R., Busch, W. (2020):
  Mixture toxicity analysis in zebrafish embryo a time and concentration resolved study on mixture effect predictivity
  Environ. Sci. Eur. 32 , art. 143
  full text (doi)
• Krämer, S., Busch, W., Schüttler, A. (2020):
  A self-organizing map of the fathead minnow liver transcriptome to identify consistent toxicogenomic patterns across chemical fingerprints
  Environ. Toxicol. Chem. 39 (3), 526 - 537
  full text (doi)
• Shatilina, Z., Drozdova, P., Bedulina, D., Rivarola-Duarte, L., Schreiber, S., Otto, C., Jühling, F., Aulhorn, S., Busch, W., Lubyaga, Y., Kondrateva, E., Pobezhimova, T., Jakob, L., Lucassen, M., Sartoris, F.J., Hackermüller, J., Pörtner, H.-O., Stadler, P.F., Luckenbach, T., Timofeyev, M. (2020):
  Transcriptome-level effects of the model organic pollutant phenanthrene and its solvent acetone in three amphipod species
  Comp. Biochem. Physiol. D-Genomics Proteomics 33 , art. 100630
  full text (doi)

2019 (6)

• Altenburger, R., Brack, W., Burgess, R.M., Busch, W., Escher, B.I., Focks, A., Hewitt, L.M., Jacobsen, B.N., López de Alda, M., Ait-Aissa, S., Backhaus, T., Ginebreda, A., Hilscherová, K., Hollender, J., Hollert, H., Neale, P.A., Schulze, T., Schymanski, E.L., Teodorovic, I., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Zonja, B., Krauss, M. (2019):
  Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures
  Environ. Sci. Eur. 31 , art. 12
  full text (doi)
• Drozdova, P., Rivarola-Duarte, L., Bedulina, D., Axenov-Gribanov, D., Schreiber, S., Gurkov, A., Shatilina, Z., Vereshchagina, K., Lubyaga, Y., Madyarova, E., Otto, C., Jühling, F., Busch, W., Jakob, L., Lucassen, M., Sartoris, F.J., Hackermüller, J., Hoffmann, S., Pörtner, H.-O., Luckenbach, T., Timofeyev, M., Stadler, P.F. (2019):
  Comparison between transcriptomic responses to short-term stress exposures of a common Holarctic and endemic Lake Baikal amphipods
  BMC Genomics 20 , art. 712
  full text (doi)
• Leuthold, D., Klüver, N., Altenburger, R., Busch, W. (2019):
  Can environmentally relevant neuroactive chemicals specifically be detected with the locomotor response test in zebrafish embryos?
  Environ. Sci. Technol. 53 (1), 482 - 493
  full text (doi)
• Schüttler, A., Altenburger, R., Ammar, M., Bader-Blukott, M., Jakobs, G., Knapp, J., Krüger, J., Reiche, K., Wu, G.-M., Busch, W. (2019):
  Map and model—moving from observation to prediction in toxicogenomics
  GigaScience 8 (6), giz057
  full text (doi)
• Serra, H., Scholze, M., Altenburger, R., Busch, W., Budzinski, H., Brion, F., Aït-Aïssa, S. (2019):
  Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays
  Chemosphere 227 , 334 - 344
  full text (doi)
• Weil, M., Mackenzie, K., Foit, K., Kühnel, D., Busch, W., Bundschuh, M., Schulz, R., Duis, K. (2019):
  Environmental risk or benefit? Comprehensive risk assessment of groundwater treated with nano Fe⁰-based Carbo-Iron®
  Sci. Total Environ. 677 , 156 - 166
  full text (doi)

2018 (6)

• Altenburger, R., Scholze, M., Busch, W., Escher, B.I., Jakobs, G., Krauss, M., Krüger, J., Neale, P.A., Ait-Aissa, S., Almeida, A.C., Seiler, T.-B., Brion, F., Hilscherová, K., Hollert, H., Novák, J., Schlichting, R., Serra, H., Shao, Y., Tindall, A., Tolefsen, K.-E., Umbuzeiro, G., Williams, T.D., Kortenkamp, A. (2018):
  Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays
  Environ. Int. 114 , 95 - 106
  full text (doi)
• Beckers, L.-M., Busch, W., Krauss, M., Schulze, T., Brack, W. (2018):
  Characterization and risk assessment of seasonal and weather dynamics in organic pollutant mixtures from discharge of a separate sewer system
  Water Res. 135 , 122 - 133
  full text (doi)
• Legradi, J.B., Di Paolo, C., Kraak, M.H.S., van der Geest, H.G., Schymanski, E.L., Williams, A.J., Dingemans, M.M.L., Massei, R., Brack, W., Cousin, X., Begout, M.-L., van der Oost, R., Carion, A., Suarez‑Ulloa, V., Silvestre, F., Escher, B.I., Engwall, M., Nilén, G., Keiter, S.H., Pollet, D., Waldmann, P., Kienle, C., Werner, I., Haigis, A.-C., Knapen, D., Vergauwen, L., Spehr, M., Schulz, W., Busch, W., Leuthold, D., Scholz, S., vom Berg, C.M., Basu, N., Murphy, C.A., Lampert, A., Kuckelkorn, J., Grummt, T., Hollert, H. (2018):
  An ecotoxicological view on neurotoxicity assessment
  Environ. Sci. Eur. 30 , art. 46
  full text (doi)
• Massei, R., Busch, W., Wolschke, H., Schinkel, L., Bitsch, M., Schulze, T., Krauss, M., Brack, W. (2018):
  Screening of pesticide and biocide patterns as risk drivers in sediments of major European river mouths: ubiquitous or river basin-specific contamination?
  Environ. Sci. Technol. 52 (4), 2251 - 2260
  full text (doi)
• Neale, P.A., Brack, W., Ait-Aissa, S., Busch, W., Hollender, J., Krauss, M., Maillot-Maréchal, E., Munz, N.A., Schlichting, R., Schulze, T., Vogler, B., Escher, B.I. (2018):
  Solid-phase extraction as sample preparation of water samples for cell-based and other in vitro bioassays
  Environ. Sci.-Proc. Imp. 20 (3), 493 - 504
  full text (doi)
• Whalley, C., Mohaupt, V., Busch, W., van den Roovaart, J., van Dujnhoven, N., Kirst, I., Schmedtje, U., Altenburger, R., Sommer, L. (2018):
  Chemicals in European waters : knowledge developments
  EEA Report 18/2018
  Office for Official Publications of the European Communities, Luxembourg, 76 pp.
  full text (doi)

2017 (6)

• Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F. (2017):
  From the exposome to mechanistic understanding of chemical-induced adverse effects
  Environ. Int. 99 , 97 - 106
  full text (doi)
• Kühnert, A., Vogs, C., Seiwert, B., Aulhorn, S., Altenburger, R., Hollert, H., Küster, E., Busch, W. (2017):
  Biotransformation in the zebrafish embryo – temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[a]anthracene
  Environ. Pollut. 230 , 1 - 11
  full text (doi)
• Neale, P.A., Altenburger, R., Aït-Aïssa, S., Brion, F., Busch, W., De Aragão Umbuzeiro, G., Denison, M.S., Du Pasquier, D., Hilscherová, K., Hollert, H., Morales, D.A., Novák, J., Schlichting, R., Seiler, T.-B., Serra, H., Shao, Y., Tindall, A.J., Tollefsen, K.E., Williams, T.D., Escher, B.I. (2017):
  Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water
  Water Res. 123 , 734 - 750
  full text (doi)
• Neale, P.A., Munz, N.A., Aїt-Aїssa, S., Altenburger, R., Brion, F., Busch, W., Escher, B.I., Hilscherová, K., Kienle, C., Novák, J., Seiler, T.-B., Shao, Y., Stamm, C., Hollender, J. (2017):
  Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams
  Sci. Total Environ. 576 , 785 - 795
  full text (doi)
• Schmidt, S., Busch, W., Altenburger, R. (2017):
  Biotestverfahren zur Abschätzung von Wirkpotenzialen in der aquatischen Umwelt : Vorschlag einer modularen Biotestbatterie für das aquatische Umweltmonitoring als Ergebnis einer systematischen Literaturrecherche und Bewertung
  LUBW Landesanstalt für Umwelt Baden-Württemberg, Karlsruhe, 98 S.
• Schüttler, A., Reiche, K., Altenburger, R., Busch, W. (2017):
  The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis
  Toxicol. Sci. 157 (2), 291 - 304
  full text (doi)

2016 (3)

• Brack, W., Ait-Aissa, S., Burgess, R.M., Busch, W., Creusot, N., Di Paolo, C., Escher, B.I., Hewitt, L.M., Hilscherova, K., Hollender, J., Hollert, H., Jonker, W., Kool, J., Lamoree, M., Muschket, M., Neumann, S., Rostkowski, P., Ruttkies, C., Schollee, J., Schymanski, E.L., Schulze, T., Seiler, T.-B., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Krauss, M. (2016):
  Effect-directed analysis supporting monitoring of aquatic environments — An in-depth overview
  Sci. Total Environ. 544 , 1073 - 1118
  full text (doi)
• Busch, W., Schmidt, S., Kühne, R., Schulze, T., Krauss, M., Altenburger, R. (2016):
  Micropollutants in European rivers: A mode of action survey to support the development of effect-based tools for water monitoring
  Environ. Toxicol. Chem. 35 (8), 1887 - 1899
  full text (doi)
• Schmidt, S., Busch, W., Altenburger, R., Küster, E. (2016):
  Mixture toxicity of water contaminants-effect analysis using the zebrafish embryo assay (Danio rerio)
  Chemosphere 152 , 503 - 512
  full text (doi)

2015 (4)

• Altenburger, R., Ait-Aissa, S., Antczak, P., Backhaus, T., Barceló, D., Seiler, T.-B., Brion, F., Busch, W., Chipman, K., López de Alda, M., De Aragão Umbuzeiro, G., Escher, B.I., Falciani, F., Faust, M., Focks, A., Hilscherova, K., Hollender, J., Hollert, H., Jäger, F., Jahnke, A., Kortenkamp, A., Krauss, M., Lemkine, G.F., Munthe, J., Neumann, S., Schymanski, E.L., Scrimshaw, M., Segner, H., Slobodnik, J., Smedes, F., Kughathas, S., Teodorovic, I., Tindall, A.J., Tollefsen, K.E., Walz, K.-H., Williams, T.D., van den Brink, P.J., van Gils, J., Vrana, B., Zhang, X., Brack, W. (2015):
  Future water quality monitoring — Adapting tools to deal with mixtures of pollutants in water resource management
  Sci. Total Environ. 512-513 , 540 - 551
  full text (doi)
• Luckenbach, T., Küster, E., Busch, W., Scholz, S., Altenburger, R. (2015):
  What determines chemical uptake by the zebrafish embryo model?
  Toxicol. Lett. 238 (2, Suppl.), S54
  full text (doi)
• Smetanová, S., Riedl, J., Zitzkat, D.P., Altenburger, R., Busch, W. (2015):
  High-throughput concentration–response analysis for omics datasets
  Environ. Toxicol. Chem. 34 (9), 2167 - 2180
  full text (doi)
• Weil, M., Meißner, T., Busch, W., Springer, A., Kühnel, D., Schulz, R., Duis, K. (2015):
  The oxidized state of the nanocomposite Carbo-Iron® causes no adverse effects on growth, survival and differential gene expression in zebrafish
  Sci. Total Environ. 530-531 , 198 - 208
  full text (doi)

2014 (2)

• Böhme, S., Stärk, H.-J., Meißner, T., Springer, A., Reemtsma, T., Kühnel, D., Busch, W. (2014):
  Quantification of Al₂O₃ nanoparticles in human cell lines applying inductively coupled plasma mass spectrometry (neb-ICP-MS, LA-ICP-MS) and flow cytometry-based methods
  J. Nanopart. Res. 16 , 2592
  full text (doi)
• Escher, B.I., Allinson, M., Altenburger, R., Bain, P.A., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulsen, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yang, M., Yeung, B.H.Y., Zhang, X., Leusch, F.D.L. (2014):
  Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
  Environ. Sci. Technol. 48 (3), 1940 - 1956
  full text (doi)

2012 (3)

• Altenburger, R., Scholz, S., Schmitt-Jansen, M., Busch, W., Escher, B.I. (2012):
  Mixture toxicity revisited from a toxicogenomic perspective
  Environ. Sci. Technol. 46 (5), 2508 - 2522
  full text (doi)
• Büttner, A., Busch, W., Klüver, N., Giannis, A., Scholz, S. (2012):
  Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine
  Reprod. Toxicol. 33 (2), 254 - 263
  full text (doi)
• Kühnel, D., Scheffler, K., Wellner, P., Meißner, T., Potthoff, A., Busch, W., Springer, A., Schirmer, K. (2012):
  Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro
  J. Hazard. Mater. 227-228 , 418 - 426
  full text (doi)

2011 (3)

• Busch, W., Bastian, S., Trahorsch, U., Iwe, M., Kühnel, D., Meißner, T., Springer, A., Gelinsky, M., Richter, V., Ikonomidou, C., Potthoff, A., Lehmann, I., Schirmer, K. (2011):
  Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties
  J. Nanopart. Res. 13 (1), 293 - 310
  full text (doi)
• Busch, W., Duis, K., Fenske, M., Maack, G., Legler, J., Padilla, S., Strähle, U., Witters, H., Scholz, S. (2011):
  The zebrafish embryo model in toxicology and teratology, September 2-3, 2010, Karlsruhe, Germany
  Reprod. Toxicol. 31 (4), 585 - 588
  full text (doi)
• Klüver, N., Yang, L., Busch, W., Scheffler, K., Scheffler, P., Strähle, U., Scholz, S. (2011):
  Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression
  PLoS One 6 (12), e29063
  full text (doi)

2010 (4)

• Busch, W. (2010):
  Toxicity of engineered nanoparticles towards vertebrate cells in vitro
  Dissertation, Martin-Luther-Universität Halle-Wittenberg
  PhD Dissertation 15/2010
  Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, 150 pp.
  full text (url)
• Busch, W., Kühnel, D., Schirmer, K., Scholz, S. (2010):
  Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes
  BMC Genomics 11 , art. 65
  full text (doi)
• Meissner, T., Kühnel, D., Busch, W., Oswald, S., Richter, V., Michaelis, A., Schirmer, K., Potthoff, A. (2010):
  Physical-chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations
  Nanotoxicology 4 (2), 196 - 206
  full text (doi)
• Stärk, H.-J., Kühnel, D., Busch, W., Wellner, P., Schirmer, C. (2010):
  Charakterisierung der Aufnahme von Wolframkarbid-Nanopartikeln durch Humanzellen mittels LA-ICP-MS
  In: Otto, M., Bulska, E., Knapp, G., Schlemmer, G., Ullrich, A., Welz, B., Wennrich, R. (Hrsg.)
  CANAS '09 - Colloquium Analytische Atomspektroskopie, 22.-25. März 2009, Freiberg
  TU Bergakademie Freiberg, Institut für Analytische Chemie, Freiberg, S. 44 - 44

2009 (5)

• Bastian, S., Busch, W., Kühnel, D., Springer, A., Meißner, T., Holke, R., Scholz, S., Iwe, M., Pompe, W., Gelinsky, M., Potthoff, A., Richter, V., Ikonomidou, H., Schirmer, K. (2009):
  Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro
  Environ. Health Perspect. 117 (4), 530 - 536
  full text (doi)
• Böselt, I., Römpler, H., Hermsdorf, T., Thor, D., Busch, W., Schulz, A., Schöneberg, T. (2009):
  Involvement of the V2 vasopressin receptor in adaptation to limited water supply
  PLoS One 4 (5), e5573
  full text (doi)
• Busch, W., Kühnel, D., Springer, A., Meissner, T., Gelinsky, M., Potthoff, A., Scholz, S., Richter, V., Schirmer, K. (2009):
  Tungsten carbide and tungsten carbide cobalt nanoparticle toxicity: The role of cellular particle uptake, leached ions and cobalt bioavailability
  Toxicol. Lett. 189 (Suppl. 1), S185 - S185
  full text (doi)
• Kühnel, D., Busch, W., Meissner, T., Springer, A., Potthoff, A., Richter, V., Gelinsky, M., Scholz, S., Schirmer, K. (2009):
  Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line
  Aquat. Toxicol. 93 (2-3), 91 - 99
  full text (doi)
• Potthoff, A., Meißner, T., Richter, V., Busch, W., Kühnel, D., Bastian, S., Iwe, M., Springer, A. (2009):
  Evaluation of health risks of nanoparticles - a contribution to a sustainable development of nanotechnology
  In: Kny, E. (ed.)
  Nanocomposite materials
  Solid State Phenomena 151
  Trans Tech Publications, Durnten-Zurich, p. 183 - 189
  full text (doi)

2005 (2)

• Römpler, H., Sangkuhl, K., Busch, W., Schöneberg, T., Schulz, A. (2005):
  Structural evolution of the V2-receptor in mammals
  Naunyn-Schmiedebergs Arch. Pharmacol. 371 (Suppl. 1), R15
• Sangkuhl, K., Römpler, H., Busch, W., Karges, B., Schöneberg, T. (2005):
  Nephrogenic diabetes insipidus caused by mutation of Tyr205: A key residue of V2 vasopressin receptor function
  Hum. Mutat. 25 (5), 505
  full text (doi)