Functional Metabolomics       

The metabolome of an organism is influenced by many different genetic and environmental factors. Thus, it depicts a complex and dynamic picture of characteristic properties of the metabolism. Our team focuses on the analysis of metabolites from intestinal microbiome as well as the metabolome of the host (Human samples from cohorts and animal models). We are interested in changes in metabolites due to external stress factors (like diseases, environmental pollutants, chemicals, drugs, diet etc.). Targeted and untargeted metabolomics approaches in combination with other OMCIS-techniques established in our working group (16S rRNA gene profiling, Metatranskriptomics, isotopic tracer analysis) are used to investigate these research questions.    


Higher education institutes  
University of Leipzig SFB 1052 Mechanisms of Obesity
RWTH Aachen SFB 1352 The Intestinal-Liver Axis - Functional Relationships and Therapeutic Strategies
Research institutions  
Max Planck Institute for Human Cognitive and Brain Sciences Microbiome-Gut-Brain-Axis
Helmholtz Institute for Metabolic, Obesety and Vascular Research, HI-MAG  
Christian-Albrechts-University Kiel Institute for Medical Systems Biology
University Hospital Bonn Section of Endocrinology, Diabetology and Metabolic Medicine
Interdisciplinary Centre for Clinical Research IZKF Erlangen
Fraunhofer IZI / Coburg University of Applied Sciences  
German Aerospace Centre  
Julius Kühn Institute for Bee Research JKI Braunschweig  
Novo Nordisk Foundation MATOMIC - Mathematicical Modelling of Health and Disease