Prof. Dr. Jana Schor
(née Hertel)
Head of Bio-Data Science
Helmholtz Centre for Environmental Research - UFZ
Department Computational Biology
Permoserstr. 15
04318 Leipzig
GERMANY
Building: Building 4.1
Room: Room 238
Phone: +49 341 6025 4779
Email: jana.schor@ufz.de
Curriculum Vitae
Current position
Head of Bio-Data Science Group, Department Computational Biology and Chemistry
Professorship
Bio-Data Science, Faculty of Mathematics and Computer Science, University of Leipzig, Germany
Previous position
Head of Bioinformatics, Department Computational Biology
Scientific degrees
- Professorship Bio-Data Science (2024)
- PhD Computer Science / Bioinformatics (2008)
- Diploma Computer Science (2005)
Research:
My research advances bio-data science and AI for human and environmental health, with a particular focus on developing transparent, credible, and practically useful computational methods for complex scientific data. I work at the interface of data integration, machine learning, graph-based AI, and domain-grounded large language models to enable new ways of analyzing, interpreting, and accessing heterogeneous data in environmental and life sciences.
A central aim of my work is to transform fragmented, large-scale data into structured, queryable, and scientifically actionable knowledge. To this end, I develop and apply methods from statistical learning, machine learning, deep learning, and knowledge representation, with strong emphasis on data integration across diverse sources, modalities, and levels of biological and environmental organization. My research supports both predictive modeling and hypothesis generation, particularly in ecological, toxicological, and health-related contexts.
An important focus of my work is the development of trustworthy AI. I therefore place strong emphasis on explainability, uncertainty quantification, and reproducible research workflows to ensure that computational results are transparent, robust, and valuable for science and decision-making. More recently, I have been working extensively on agentic AI systems and domain-specific LLM applications, especially where large language models are grounded in structured scientific knowledge to provide traceable and accessible interfaces to complex data.
- Data integration, semantic modelling, and analysis using knowledge graphs and graph databases
- Graph machine learning, including graph neural networks for complex and interconnected scientific data
- Explainable AI and uncertainty quantification for more credible computational prediction
- Grounded LLMs and agentic AI for transparent, domain-specific access to scientific knowledge
- Reproducible and scalable computational workflows for environmental and life science research
Infrastructure, programs and approaches:
- High-performance computing for large-scale data processing
- GPU-based training and deployment of AI models
- Statistical learning, machine learning, deep learning, and graph-based learning
- Knowledge graphs and graph databases for semantic integration and structured reasoning
- Large language models and agent-based AI systems for domain-grounded scientific applications
- Programming and query languages including R, Python, shell scripting, awk, Cypher, and SQL
Teaching and educational offers:
In addition to my research, I am dedicated to teaching future data scientists and computer science students. Via the university Leipzig, I offer courses in statistical learning, R programming, and an interactive Data Science curriculum designed to prepare students comprehensively for the field. These courses include:
- Hands-on training in R and Python,
- Version control with Git,
- Agile project and self-management practices,
- Storytelling with data,
- Crafting compelling and representative visuals and
- Developing strong presentation skills.
- I aim to equip students with a robust, practical skill set that prepares them for success in real-world data science roles.
Publications
My five recent most essential publications are sorted by relevance:
- Schor, J., Scheibe, P., Bernt, M., Busch, W., Lai, C., Hackermüller, J. (2022):
AI for predicting chemical-effect associations at the chemical universe level — deepFPlearn
Brief. Bioinform. 23 (5), bbac257 10.1093/bib/bbac257 - Soulios, K., Scheibe, P., Bernt, M., Hackermüller, J., Schor, J. (2023):
deepFPlearn+: enhancing toxicity prediction across the chemical universe using graph neural networks
Bioinformatics 39 (12), btad713 10.1093/bioinformatics/btad713 - Canzler, S., Schor, J., Busch, W., Schubert, K., Rolle-Kampczyk, U.E., Seitz, H., Kamp, H., von Bergen, M., Buesen, R., Hackermüller, J. (2020):
Prospects and challenges of multi‑omics data integration in toxicology
Arch. Toxicol. 94 (2), 371 - 388 10.1007/s00204-020-02656-y - Völkner, M., Wagner, F., Steinheuer, L.M., Carido, M., Kurth, T., Yazbeck, A., Schor, J., Wieneke, S., Ebner, L.J.A., Del Toro Runzer, C., Taborsky, D., Zoschke, K., Vogt, M., Canzler, S., Hermann, A., Khattak, S., Hackermüller, J., Karl, M.O. (2022):
HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids
Nat. Commun. 13 , art. 6183 10.1038/s41467-022-33848-y - Gutsfeld, S., Wehmas, L., Omoyeni, I.E., Schweiger, N., Leuthold, D., Michaelis, P., Howey, X.M., Gaballah, S., Herold, N., Vogs, C., Wood, C., Bertotto, L., Wu, G.-M., Klüver, N., Busch, W., Scholz, S., Schor, J., Tal, T. (2024):
Investigation of peroxisome proliferator-activated receptor genes as requirements for visual startle response hyperactivity in larval zebrafish exposed to structurally similar per- and polyfluoroalkyl substances (PFAS)
Environ. Health Perspect. 132 (7), art. 077007 10.1289/EHP13667
Index:
You could use our publication index for further requests.
2026 (2)
- Canzler, S., Lehmann, J., Schor, J., Busch, W., Iacono, G., Hackermüller, J. (2026):
From toxicogenomics data to cumulative assessment groups: a framework for chemical grouping
Arch. Toxicol. 100 (1), 173 - 191
10.1007/s00204-025-04133-w - Spath, J., Raab, J., Schor, J., Scholz, S., Gutsfeld, S., Tal, T. (2026):
The zebrafish visual and acoustic motor response (VAMR) assay has the potential to add value to the developmental neurotoxicity in vitro battery (DNT IVB)
NeuroToxicology 114 , art. 103414
10.1016/j.neuro.2026.103414
2025 (12)
- Canzler, S., Lehmann, J., Schor, J., Busch, W., Iacono, G., Hackermüller, J. (2025):
From toxicogenomics data to cumulative assessment groups: A framework for chemical grouping
Toxicol. Lett. 411 (Supplement), S55 - S56
10.1016/j.toxlet.2025.07.163 - Gad, M., Tayyebi Sabet Khomami, N., Krieg, R., Schor, J., Philippe, A., Lechtenfeld, O.J. (2025):
Environmental drivers of dissolved organic matter composition across central European aquatic systems: A novel correlation-based machine learning and FT-ICR MS approach
Water Res. 273 , art. 123018
10.1016/j.watres.2024.123018 - Mutlu, İ., Hackermüller, J., Schor, J. (2025):
Automated curation of spatial metadata in environmental monitoring data
Ecol. Inform. 86 , art. 103038
10.1016/j.ecoinf.2025.103038 - Mutlu, İ., Schor, J., Hackermüller, J. (2025):
CleanGeoStreamR: Automated curation of spatially annotated environmental monitoring data
Version: v1 Zenodo
10.5281/zenodo.16880619 - Scheibe, P., Schor, J. (2025):
AI-driven science communication: Leveraging LLMs and knowledge graphs for seamless knowledge exchange
bioRxiv
10.1101/2025.07.04.663152 - Schor, J., Bohring, H., Scheibe, P. (2025):
EcoToxFred - Dialogues with a Knowledge Keeper
Zenodo
10.5281/zenodo.15696402 - Schor, J., Mutlu, İ., Busch, W., Bumberger, J., Schulze, T., Ulrich, N., Hassan, K.N., Krauss, M., Brack, W., Doan, T., Bingert, S., Hackermüller, J. (2025):
Neo4j Container Link for the Curated Dataset in ChEOS Project [Data set]
Zenodo
10.5281/zenodo.14616124 - Schor, J., Scheibe, P., Bernt, M., Hackermüller, J. (2025):
deepFPlearn - AI for predicting chemical-effect associations at the chemical universe level
Version: v1.2 Zenodo
10.5281/zenodo.13329413 - Schor, J., Schulze, T., Ulrich, N., Mutlu, İ., Krauss, M., Brack, W., Doan, T., Bingert, S., Bumberger, J., Busch, W., Hackermüller, J. (2025):
Chemical mixture risk drivers and their heterogeneity in European freshwaters
Environ. Int. 205 , art. 109881
10.1016/j.envint.2025.109881 - Schor, J., Schulze, T., Ulrich, N., Mutlu, İ., Krauss, M., Brack, W., Doan, T., Bingert, S., Bumberger, J., Busch, W., Hackermüller, J. (2025):
Chemical mixture risk drivers and their heterogeneity in European freshwaters - supplementary data - v1
Zenodo
10.5281/zenodo.15804639 - Schor, J., Schulze, T., Ulrich, N., Mutlu, İ., Krauss, M., Brack, W., Doan, T., Bingert, S., Bumberger, J., Busch, W., Hackermüller, J. (2025):
Chemical mixture risk drivers and their heterogeneity in European freshwaters - supplementary data - v3
Zenodo
10.5281/zenodo.17249758 - Schor, J., Schulze, T., Ulrich, N., Mutlu, İ., Krauss, M., Brack, W., Doan, T., Bingert, S., Bumberger, J., Busch, W., Hackermüller, J. (2025):
Chemical Mixture Risk Drivers in European Freshwaters: Analysis Software and Workflow
Version: v1 Zenodo
10.5281/zenodo.17909110
2024 (5)
- Aldehoff, A.S., Karkossa, I., Goerdeler, C., Krieg, L., Schor, J., Engelmann, B., Wabitsch, M., Landgraf, K., Hackermüller, J., Körner, A., Rolle-Kampczyk, U., Schubert, K., von Bergen, M. (2024):
Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis
iScience 27 (6), art. 109711
10.1016/j.isci.2024.109711 - Gutsfeld, S., Wehmas, L., Omoyeni, I.E., Schweiger, N., Leuthold, D., Michaelis, P., Howey, X.M., Gaballah, S., Herold, N., Vogs, C., Wood, C., Bertotto, L., Wu, G.-M., Klüver, N., Busch, W., Scholz, S., Schor, J., Tal, T. (2024):
Investigation of peroxisome proliferator-activated receptor genes as requirements for visual startle response hyperactivity in larval zebrafish exposed to structurally similar per- and polyfluoroalkyl substances (PFAS)
Environ. Health Perspect. 132 (7), art. 077007
10.1289/EHP13667 - Mutlu, İ., Schor, J. (2024):
Collection of chemical occurance data from NORMAN surface water database and other related files
Zenodo
10.5281/zenodo.11395194 - Mutlu, İ., Schor, J. (2024):
Chemical occurence data curation results with CleanGeoStreamR
Zenodo
10.5281/zenodo.13799955 - Schor, J. (2024):
deepFPlearn - datasets, models, and configurations
Zenodo
10.5281/zenodo.14409985
2023 (3)
- Schor, J., Scheibe, P., Soulios, K., Bernt, M. (2023):
deepFPlearn +: enhancing toxicity prediction across the chemical universe using graph neural networks
Version: v2.0 Zenodo
10.5281/zenodo.13329443 - Soulios, K., Scheibe, P., Bernt, M., Hackermüller, J., Schor, J. (2023):
deepFPlearn+: enhancing toxicity prediction across the chemical universe using graph neural networks
Bioinformatics 39 (12), btad713
10.1093/bioinformatics/btad713 - Soulios, K., Scheibe, P., Bernt, M., Hackermüller, J., Schor, J. (2023):
deepFPlearn+
Zenodo
10.5281/zenodo.8146252
2022 (5)
- Schor, J. (2022):
deepFPlearn - generic autoencoder model
Zenodo
10.5281/zenodo.14393931 - Schor, J., Scheibe, P., Bernt, M., Busch, W., Lai, C., Hackermüller, J. (2022):
AI for predicting chemical-effect associations at the chemical universe level — deepFPlearn
Brief. Bioinform. 23 (5), bbac257
10.1093/bib/bbac257 - Schor, J., Yazbeck, A.M, Völkner, M., Hackermüller, J., Karl, M.O. (2022):
HBEGF-TNF induces a complex retinal pathology with macular degeneration hallmarks in human organoids
Gene Expression Omnibus - Velandia-Huerto, C.A., Yazbeck, A.M., Schor, J., Stadler, P.F. (2022):
Evolution and phylogeny of microRNAs — Protocols, pitfalls, and problems
In: Allmer, J., Yousef, M. (eds.)
miRNomics. MicroRNA biology and computational analysis
Methods in Molecular Biology 2257
Springer Nature, p. 211 - 233
10.1007/978-1-0716-1170-8_11 - Völkner, M., Wagner, F., Steinheuer, L.M., Carido, M., Kurth, T., Yazbeck, A., Schor, J., Wieneke, S., Ebner, L.J.A., Del Toro Runzer, C., Taborsky, D., Zoschke, K., Vogt, M., Canzler, S., Hermann, A., Khattak, S., Hackermüller, J., Karl, M.O. (2022):
HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids
Nat. Commun. 13 , art. 6183
10.1038/s41467-022-33848-y
Index:
You could use our publication index for further requests.
2021 (2)
- Schubert, K., Karkossa, I., Schor, J., Engelmann, B., Steinheuer, L.M., Bruns, T., Rolle-Kampczyk, U., Hackermüller, J., von Bergen, M. (2021):
A multi-omics analysis of mucosal-associated-invariant T cells reveals key drivers of distinct modes of activation
Front. Immunol. 12 , art. 616967
10.3389/fimmu.2021.616967 - Völkner, M., Kurth, T., Schor, J., Ebner, L.J.A., Bardtke, L., Kavak, C., Hackermüller, J., Karl, M.O. (2021):
Mouse retinal organoid growth and maintenance in longer-term culture
Front. Cell. Dev. Biol. 9 , art. 645704
10.3389/fcell.2021.645704
2020 (3)
- Balogh, G., Bernhart, S.H., Stadler, P.F., Schor, J. (2020):
A probabilistic version of Sankoff’s maximum parsimony algorithm
J. Bioinform. Comput. Biol. 18 (1), art. 2050004
10.1142/S0219720020500043 - Canzler, S., Schor, J., Busch, W., Schubert, K., Rolle-Kampczyk, U.E., Seitz, H., Kamp, H., von Bergen, M., Buesen, R., Hackermüller, J. (2020):
Prospects and challenges of multi‑omics data integration in toxicology
Arch. Toxicol. 94 (2), 371 - 388
10.1007/s00204-020-02656-y - Olms, C., Schor, J., Yahiaoui-Doktor, M. (2020):
Potential co-factors of an intraoral contact allergy — A cross-sectional study
Dent. J. 8 (3), art. 83
10.3390/dj8030083
2019 (3)
- Bauer, M., Hackermüller, J., Schor, J., Schreiber, S., Fink, B., Pierzchalski, A., Herberth, G. (2019):
Specific induction of the unique GPR15 expression in heterogeneous blood lymphocytes by tobacco smoking
Biomarkers 24 (3), 217 - 224
10.1080/1354750X.2018.1539769 - Kämpf, C., Specht, M., Scholz, A., Puppel, S.-H., Doose, G., Reiche, K., Schor, J., Hackermüller, J. (2019):
uap: reproducible and robust HTS data analysis
BMC Bioinformatics 20 , art. 664
10.1186/s12859-019-3219-1 - Schubert, K., Schor, J., Kratochvil, I., Hackermüller, J., von Bergen, M. (2019):
Multi-omics profiling of MAIT cells reveals specific patterns of antigen-dependent and -independent activation
Eur. J. Immunol. 49 (Suppl. 1), 141
10.1002/eji.201970300
2018 (1)
- Canzler, S., Stadler, P.F., Schor, J. (2018):
The fungal snoRNAome
RNA 24 (3), 342 - 360
10.1261/rna.062778.117
2017 (2)
- Canzler, S., Stadler, P.F., Hertel, J. (2017):
Evolution of fungal U3 snoRNAs: Structural variation and introns
Non-Coding RNA 3 (1), art. 3
10.3390/ncrna3010003 - Yazbeck, A.M., Tout, K.R., Stadler, P.F., Hertel, J. (2017):
Towards a consistent, quantitative evaluation of microRNA evolution
J. Integr. Bioinform. 14 (1)
10.1515/jib-2016-0013
2016 (5)
- Bhattacharya, D.P., Canzler, S., Kehr, S., Hertel, J., Grosse, I., Stadler, P.F. (2016):
Phylogenetic distribution of plant snoRNA families
BMC Genomics 17 , art. 969
10.1186/s12864-016-3301-2 - Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E.G., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M.J., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.-N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W.H., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016):
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
Nature Genet. 48 (4), 427 - 437
10.1038/ng.3526 - Canzler, S., Stadler, P.F., Hertel, J. (2016):
U6 snRNA intron insertion occurred multiple times during fungi evolution
RNA Biol. 13 (2), 119 - 127
10.1080/15476286.2015.1132139 - de Araujo Oliveira, J.V., Costa, F., Backofen, R., Stadler, P.F., Walter, M.E.M.T., Hertel, J. (2016):
SnoReport 2.0: new features and a refined Support Vector Machine to improve snoRNA identification
BMC Bioinformatics 17 (Suppl 18), art. 464
10.1186/s12859-016-1345-6 - Fontenot, Q., Ferrara, A., Searle, S.M.J., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.-N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W.H., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E.G., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D. (2016):
Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons (vol 48, pg 427, 2016)
Nature Genet. 48 (6), 700 - 700
10.1038/ng0616-700c
For older publications processed at the Uni Leipzig and/or Uni Wien under my birth name Jana Hertel
Professur für Bioinformatik
Institut für Informatik
Universität Leipzig
Härtelstr. 16-18
D-04107 Leipzig
Institut für Theoretische Chemie
Universität Wien
Währinger Straße 17
A-1090 Wien
please refer to my ORCID profile.