Dr. Sebastian Canzler

(née Bartschat)

Postdoc

Helmholtz Centre for Environmental Research - UFZ
Young Investigators Group Bioinformatics and Transcriptomics
Department Molecular Systems Biology
Permoserstr. 15
04318 Leipzig
GERMANY
Building: Building 4.1 und 4.2
Room: Room 239
Phone: +49 341 6025 1353
Email: sebastian.canzler@ufz.de

Research interests

  • Methodenenwicklung für die Integration von Multi-omics Daten
  • Datenintegration in der Systembiologie
  • Multi-omics Datenanalyse im Bereich der Risikobewertung von Chemikalien
  • Nutzung von Methoden des Maschinellen Lernerns zur Unterscheidung von adaptiven und adversen Reaktionen
  • Nutzung von Multi-omics Daten zur Erstellung bzw. der Erweiterung von Adverse Outcome Pathways (AOP)
  • Nicht-kodierende RNAs
  • Regulatorische Netzwerke


Ongoing Projects


ResearchGate

Research interests

  • Method development for multi-omics data integration
  • Data integration in systems biology
  • Multi-omics data analysis in chemical risk assessment
  • Machine learning principles to discriminate adaptive from adverse responses
  • Using multi-omics to detect and refine Adverse Outcome Pathways (AOP)
  • Functional, non-coding RNAs
  • Regulatory networks involving non-coding RNAs
  • Non-coding RNAs in disease and toxicity, drug discovery, and biomarkers


Publications

Index:

You could use our publication index for further requests.

2024 (3)

to index

2023 (4)

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2022 (4)

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2021 (2)

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2020 (2)

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 Publications processed at the university of Leipzig


Professur für Bioinformatik
Institut für Informatik
Universität Leipzig
Härtelstr. 16-18
D-04107 Leipzig


2018

  • Canzler S., Stadler P. F., and Hertel J. The fungal snoRNAome.
    RNA, 24(3):342-360, Mar 2018

2017

  • Canzler S., Stadler P. F., and Hertel J. Evolution of Fungal U3 snoRNAs:
    Structural Variation and Introns.     Non-Coding RNA, 3(1), Jan 2017.

2016


  • Patra Bhattacharya D., Canzler S., Kehr S., Hertel J., Grosse I., and Stadler
    P. F. Phylogenetic distribution of plant snorna families.
    BMC Genomics, 17(1):969, Nov 2016.
  • Canzler S., Stadler P. F., and Hertel J. U6 snRNA Intron Insertion Occurred
    Multiple Times during Fungi Evolution.
    RNA Biol, 13(2):119–27, Feb 2016.

2014


  • Schneider H., Bartschat S., Doose G., Maciel L., Pizani E., Bassani M., Torres
    F. A., Will S., Raiol T., Brígido M., Walter M. E., and Stadler P. F. Genome-
    Wide Identification of Non-coding RNAs in Komagatella pastoris str. GS115.
    In Campos S., editor, Advances in Bioinformatics and Computational Biology,
    volume 8826 of Lecture Notes in Computer Science,
    pages 115–122. Springer International Publishing, 2014.
  • Kehr S., Bartschat S., Tafer H., Stadler P. F., and Hertel J. Matching of
    Soulmates: coevolution of snoRNAs and their targets.     Mol Biol Evol,
    31(2):455–67, Feb 2014.
  • Bartschat S., Kehr S., Tafer H., Stadler P. F., and Hertel J. snoStrip: a
    snoRNA annotation pipeline.     Bioinformatics, 30(1):115–6, Jan 2014.
  • Anthon C., Tafer H., Havgaard J. H., Thomsen B., Hedegaard J., Seemann
    S. E., Pundhir S., Kehr S., Bartschat S., Nielsen M., Nielsen R. O., Fredholm
    M., Stadler P. F., and Gorodkin J. Structured RNAs and synteny regions in
    the pig genome    . BMC Genomics, 15:459, 2014.

2013

  • Huang Y., Li Y., Burt D. W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
    Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S., Magor K. E.,
    Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T., Kim K. W., Sheng
    Z., An Y., Searle S., Herrero J., Groenen M. A., Crooijmans R. P., Faraut
    T., Cai Q., Webster R. G., Aldridge J. R., Warren W. C., Bartschat S., Kehr
    S., Marz M., Stadler P. F., Smith J., Kraus R. H., Zhao Y., Ren L., Fei J.,
    Morisson M., Kaiser P., Griffin D. K., Rao M., Pitel F., Wang J., and Li N.
    The duck genome and transcriptome provide insight into an avian influenza
    virus reservoir species.     Nat Genet, 45(7):776–83, Jul 2013.

2012

  • Hertel J., Bartschat S., Wintsche A., Otto C., Students of the Bioinformatics
    Computer Lab, and Stadler P. F. Evolution of the let-7 microRNA family.
    RNA Biol, 9(3):231–41, Mar 2012.

2011

  • Marz M., Gruber A. R., Höner Zu Siederdissen C., Amman F., Badelt S.,
    Bartschat S., Bernhart S. H., Beyer W., Kehr S., Lorenz R., Tanzer A., Yusuf
    D., Tafer H., Hofacker I. L., and Stadler P. F. Animal snoRNAs and scaRNAs
    with exceptional structures.     RNA Biol, 8(6):938–46, 2011.
  • Langenberger D., Bartschat S., Hertel J., Hoffmann S., Tafer H., and Stadler
    P. F. MicroRNA or Not MicroRNA? In Norberto de Souza O., Telles G. P., and
    Palakal M., editors, Advances in Bioinformatics and Computational Biology,
    volume 6832 of Lecture Notes in Computer Science, pages 1–9. Springer Berlin
    Heidelberg, 2011.
  • Kehr S., Bartschat S., Stadler P. F., and Tafer H. PLEXY: efficient target
    prediction for box C/D snoRNAs.     Bioinformatics, 27(2):279–80, Jan 2011.

2010

  • Bartschat S. and Samuelsson T. U12 type introns were lost at multiple occasions
    during evolution.     BMC Genomics, 11:106, 2010.