Andrea Ebert, Ph. D.
Contact
Andrea Ebert, Ph. D.
Department of Computational Biology and Chemistry
Helmholtz Centre for Environmental Research - UFZ
Permoserstr. 15
04318 Leipzig, Germany
Tel: ++49 341 6025 2325
andrea.ebert@ufz.de
Curriculum Vitae
Education
2012
2009
Physics, Master of Science, Ludwig-Maximilians-Universität Munich
Physics, Bachelor of Science, Ludwig-Maximilians-Universität Munich
Professional Experience
2012 - 2016
PostDoc at Helmholtz Centre for Environmental Research
Development Engineer at Entropy GmbH
2024 (5)
- Dahley, C., Böckmann, T., Ebert, A., Goss, K.-U. (2024):
Predicting the intrinsic membrane permeability of Caco-2/MDCK cells by the solubility-diffusion model
Eur. J. Pharm. Sci. 195 , art. 106720 10.1016/j.ejps.2024.106720 - Ebert, A., Dahley, C. (2024):
Can membrane permeability of zwitterionic compounds be predicted by the solubility diffusion model?
Eur. J. Pharm. Sci. 199 , art. 106819 10.1016/j.ejps.2024.106819 - Ebert, A., Dahley, C., Goss, K.-U. (2024):
Pitfalls in evaluating permeability experiments with Caco-2/MDCK cell monolayers
Eur. J. Pharm. Sci. 194 , art. 106699 10.1016/j.ejps.2024.106699 - Kotze, S., Ebert, A., Goss, K.-U. (2024):
Effects of aqueous boundary layers and paracellular transport on the efflux ratio as a measure for active transport across cell layers
Pharmaceutics 16 (1), art. 132 10.3390/pharmaceutics16010132 - Kotze, S., Goss, K.-U., Ebert, A. (2024):
The pH-dependence of efflux ratios determined with bidirectional transport assays across cellular monolayers
Int. J. Pharm. 8 , art. 100269 10.1016/j.ijpx.2024.100269
2023 (4)
- Dahley, C., Goss, K.-U., Ebert, A. (2023):
Revisiting the pKa-Flux method for determining intrinsic membrane permeability
Eur. J. Pharm. Sci. 191 , art. 106592 10.1016/j.ejps.2023.106592 - Ebert, A., Ackermann, J., Goss, K.-U. (2023):
Mechanistic modeling of the bioconcentration of (super)hydrophobic compounds in Hyalella azteca
Environ. Sci. Pollut. Res. 30 (17), 50257 - 50268 10.1007/s11356-023-25827-7 - Goss, K.-U., Ebert, A. (2023):
Bioaccumulation assessment of superhydrophobic substances. Final report
Texte Umweltbundesamt 40/2023
Umweltbundesamt, Dessau-Roßlau, 59 pp. - McLachlan, M.S., Ebert, A., Armitage, J.M., Arnot, J.A., Droge, S.T.J. (2023):
A framework for understanding the bioconcentration of surfactants in fish
Environ. Sci.-Process Impacts 25 (7), 1238 - 1251 10.1039/D3EM00070B
2022 (4)
- Barta, T., Sandtner, W., Wachlmayr, J., Hannesschlaeger, C., Ebert, A., Speletz, A., Horner, A. (2022):
Modeling of SGLT1 in reconstituted systems reveals apparent ion-dependencies of glucose uptake and strengthens the notion of water-permeable apo states
Front. Physiol. 13 , art. 874472 10.3389/fphys.2022.874472 - Dahley, C., Garessus, E.D.G., Ebert, A., Goss, K.-U. (2022):
Impact of cholesterol and sphingomyelin on intrinsic membrane permeability
Biochim. Biophys. Acta-Biomembr. 1864 (9), art. 183953 10.1016/j.bbamem.2022.183953 - Ebert, A., Goss, K.U. (2022):
Screening of 6000 compounds for uncoupling activity: a comparison between a mechanistic biophysical model and the structural alert profiler Mitotox
Toxicol. Sci. 185 (2), 208 - 219 10.1093/toxsci/kfab139 - Ulrich, N., Ebert, A. (2022):
Can deep learning algorithms enhance the prediction of solute descriptors for linear solvation energy relationship approaches?
Fluid Phase Equilib. 555 , art. 113349 10.1016/j.fluid.2021.113349
2021 (2)
- Ebert, A., Goss, K.-U. (2021):
Model for protonophoric uncoupling: explaining discrepancies between BLM and mitochondria
Eur. Biophys. J. Biophys. Lett. 50 (Suppl. 1), 126 - 126 10.1007/s00249-021-01558-w - Ulrich, N., Goss, K.U., Ebert, A. (2021):
Exploring the octanol-water partition coefficient dataset using deep learning techniques and data augmentation
Comm. Chem. 4 , art. 90 10.1038/s42004-021-00528-9
2020 (3)
- Ebert, A., Allendorf, F., Berger, U., Goss, K.-U., Ulrich, N. (2020):
Membrane/water partitioning and permeabilities of perfluoroalkyl acids and four of their alternatives and the effects on toxicokinetic behavior
Environ. Sci. Technol. 54 (8), 5051 - 5061 10.1021/acs.est.0c00175 - Ebert, A., Goss, K.-U. (2020):
Predicting uncoupling toxicity of organic acids based on their molecular structure using a biophysical model
Chem. Res. Toxicol. 33 (7), 1835 - 1844 10.1021/acs.chemrestox.0c00063 - Schwöbel, J.A.H., Ebert, A., Bittermann, K., Huniar, U., Goss, K.-U., Klamt, A. (2020):
COSMOperm: Mechanistic prediction of passive membrane permeability for neutral compounds and ions and its pH dependence
J. Phys. Chem. B 124 (16), 3343 - 3354 10.1021/acs.jpcb.9b11728
2018 (1)
- Ebert, A., Hannesschlaeger, C., Goss, K.-U., Pohl, P. (2018):
Passive permeability of planar lipid bilayers to organic anions
Biophys. J. 115 (10), 1931 - 1941 10.1016/j.bpj.2018.09.025