Dr. Bettina Seiwert
Wissenschaftlicher Mitarbeiter (PostDoc)
Kontakt/Adresse
Dr. Bettina Seiwert
Helmholtz-Zentrum für Umweltforschung - UFZ
Department Analytik
Permoserstr. 15
04318 Leipzig, Germany
Tel: 0341 235 1394
Fax: 0341 235 451394
bettina.seiwert@ufz.de
Forschungsschwerpunkte
- Generierung und massenspektrometrische Identifizierung von Metaboliten organischer Chemikalien
- Massenspektrometrische Identifizierung und Quantifizierung anthropogener Spurenstoffen im Wasser und Urin
Curriculum Vitae
seit 01/2012
07/2009 – 12/2011
09/2007 – 06/2009
08/2003 – 07/2007
07/2001 – 10/2001
10/1998 - 05/2003
wiss. Mitarbeiter am Helmholzzentrum für Umweltforschung in Leipzig (Department Analytik)
wiss. Mitarbeiter am Institut für Pharmakologie, Pharmazie und Toxikologie des Veterinärmedizinischen Institutes der Universität Leipzig
wiss. Mitarbeiter am MPI für Molekulare Pflanzenphysiologie, Potsdam, Arbeitskreis Prof. L. Willmitzer,
Promotion in analytischer Chemie an der Universität Twente, Enschede, Niederlande, Arbeitskreis Prof. U. Karst, Titel: "Ferrocene-based derivatizing agents for LC/MS and LC/EC/MS"
ERASMUS-Aufenthalt am “Micro and Trace Analysis Center” an der Universität von Antwerpen (Belgien), Arbeitskreis: Prof. F. Adams, LC/ICP-MS von Metallothionein
Studium der Chemie (Diplom), Universität Leipzig,
Thema der Diplomarbeit : „Untersuchung nichtkovalenter
Protein-Liganden-Wechselwirkung mit ESI-FT-ICR-MS“ Arbeitskreis Prof. S. Berger
Publikationen
2024 (2)
- Foscari, A., Seiwert, B., Zahn, D., Schmidt, M., Reemtsma, T. (2024):
Leaching of tire particles and simultaneous biodegradation of leachables
Water Res. 253 , art. 121322 10.1016/j.watres.2024.121322 - Fu, Q., Seiwert, B., Reemtsma, T., Escher, B., Scholz, S., Massei, R., Grasse, N. (2024):
Impact of Biotransformation on Internal Concentrations and Specificity Classification of Organic Chemicals in the Zebrafish Embryo (Danio rerio)
Environ. Sci. Technol. 10.1021/acs.est.4c04156
2023 (5)
- Bein, E., Seiwert, B., Reemtsma, T., Drewes, J.E., Hübner, U. (2023):
Advanced oxidation processes for removal of monocyclic aromatic hydrocarbon from water: Effects of O3/H2O2 and UV/H2O2 treatment on product formation and biological post-treatment
J. Hazard. Mater. 450 , art. 131066 10.1016/j.jhazmat.2023.131066 - Foscari, A., Schmidt, N., Seiwert, B., Herzke, D., Sempéré, R., Reemtsma, T. (2023):
Leaching of chemicals and DOC from tire particles under simulated marine conditions
Front. Environ. Sci. 11 , art. 1206449 10.3389/fenvs.2023.1206449 - Grasse, N., Seiwert, B., Massei, R., Scholz, S., Fu, Q., Reemtsma, T. (2023):
Uptake and biotransformation of the tire rubber-derived contaminants 6-PPD and 6-PPD quinone in the zebrafish embryo (Danio rerio)
Environ. Sci. Technol. 57 (41), 15598 - 15607 10.1021/acs.est.3c02819 - Nihemaiti, M., Icker, M., Seiwert, B., Reemtsma, T. (2023):
Revisiting disinfection byproducts with supercritical fluid chromatography-high resolution-mass spectrometry: Identification of novel halogenated sulfonic acids in disinfected drinking water
Environ. Sci. Technol. 57 (9), 3527 - 3537 10.1021/acs.est.2c05536 - Weyrauch, S., Seiwert, B., Voll, M., Wagner, S., Reemtsma, T. (2023):
Accelerated aging of tire and road wear particles by elevated temperature, artificial sunlight and mechanical stress — A laboratory study on particle properties, extractables and leachables
Sci. Total Environ. 904 , art. 166679 10.1016/j.scitotenv.2023.166679
2022 (4)
- Halbach, K., Aulhorn, S., Lechtenfeld, O.J., Lecluse, M., Leippe, S., Reemtsma, T., Seiwert, B., Wagner, S., König, J., Luckenbach, T. (2022):
Zebrafish Oatp1d1 acts as a cellular efflux transporter of the anionic herbicide bromoxynil
Chem. Res. Toxicol. 35 (2), 315 - 325 10.1021/acs.chemrestox.1c00371 - Hanslik, L., Seiwert, B., Huppertsberg, S., Huppertsberg, T.P., Reemtsma, T., Braunbeck, T. (2022):
Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene
Aquat. Toxicol. 245 , art. 106120 10.1016/j.aquatox.2022.106120 - Junge, K.M., Buchenauer, L., Strunz, S., Seiwert, B., Thürmann, L., Rolle-Kampczyk, U.E., Röder, S., Borte, M., Kiess, W., von Bergen, M., Simon, J.C., Zenclussen, A.C., Schöneberg, T., Stangl, G.I., Herberth, G., Lehmann, I., Reemtsma, T., Polte, T. (2022):
Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study
Sci. Total Environ. 814 , art. 152676 10.1016/j.scitotenv.2021.152676 - Seiwert, B., Nihemaiti, M., Troussier, M., Weyrauch, S., Reemtsma, T. (2022):
Abiotic oxidative transformation of 6-PPD and 6-PPD quinone from tires and occurrence of their products in snow from urban roads and in municipal wastewater
Water Res. 212 , art. 118122 10.1016/j.watres.2022.118122
2021 (7)
- Karpov, M., Seiwert, B., Mordehay, V., Reemtsma, T., Polubesova, T., Chefetz, B. (2021):
Abiotic transformation of lamotrigine by redox-active mineral and phenolic compounds
Environ. Sci. Technol. 55 (3), 1535 - 1544 10.1021/acs.est.0c03631 - Klöckner, P., Seiwert, B., Wagner, S., Reemtsma, T. (2021):
Organic markers of tire and road wear particles in sediments and soils: Transformation products of major antiozonants as promising candidates
Environ. Sci. Technol. 55 (17), 11723 - 11732 10.1021/acs.est.1c02723 - Klöckner, P., Seiwert, B., Weyrauch, S., Escher, B.I., Reemtsma, T., Wagner, S. (2021):
Comprehensive characterization of tire and road wear particles in highway tunnel road dust by use of size and density fractionation
Chemosphere 279 , art. 130530 10.1016/j.chemosphere.2021.130530 - Muniz, M.S., Halbach, K., Araruna, I.C.A., Martins, R.X., Seiwert, B., Lechtenfeld, O., Reemtsma, T., Farias, D. (2021):
Moxidectin toxicity to zebrafish embryos: Bioaccumulation and biomarker responses
Environ. Pollut. 283 , art. 117096 10.1016/j.envpol.2021.117096 - Neuwald, I., Muschket, M., Zahn, D., Berger, U., Seiwert, B., Meier, T., Kuckelkorn, J., Strobel, C., Knepper, T.P., Reemtsma, T. (2021):
Filling the knowledge gap: A suspect screening study for 1310 potentially persistent and mobile chemicals with SFC- and HILIC-HRMS in two German river systems
Water Res. 204 , art. 117645 10.1016/j.watres.2021.117645 - Seiwert, B., Nihemaiti, M., Bauer, C., Muschket, M., Sauter, D., Gnirss, R., Reemtsma, T. (2021):
Ozonation products from trace organic chemicals in municipal wastewater and from metformin: peering through the keyhole with supercritical fluid chromatography-mass spectrometry
Water Res. 196 , art. 117024 10.1016/j.watres.2021.117024 - Thürmann, L., Herberth, G., Seiwert, B., Schlittenbauer, L., Rolle-Kampczyk, U., Röder, S., Sack, U., Borte, M., von Bergen, M., Trump, S., Reemtsma, T., Lehmann, I. (2021):
Prenatal paraben exposure and atopic dermatitis-related outcomes among children
Allergy 76 (10), 3122 - 3132 10.1111/all.14890
2020 (6)
- Carstens, L., Cowan, A.R., Seiwert, B., Schlosser, D. (2020):
Biotransformation of phthalate plasticizers and bisphenol A by marine-derived, freshwater, and terrestrial fungi
Front. Microbiol. 11 , art. 317 10.3389/fmicb.2020.00317 - Gawel, A., Seiwert, B., Sühnholz, S., Schmitt-Jansen, M., Mackenzie, K. (2020):
In-situ treatment of herbicide-contaminated groundwater–Feasibility study for the cases atrazine and bromacil using two novel nanoremediation-type materials
J. Hazard. Mater. 393 , art. 122470 10.1016/j.jhazmat.2020.122470 - Halbach, K., Ulrich, N., Goss, K.-U., Seiwert, B., Wagner, S., Scholz, S., Luckenbach, T., Bauer, C., Schweiger, N., Reemtsma, T. (2020):
Yolk sac of zebrafish embryos as backpack for chemicals?
Environ. Sci. Technol. 54 (16), 10159 - 10169 10.1021/acs.est.0c02068 - Klöckner, P., Seiwert, B., Eisentraut, P., Braun, U., Reemtsma, T., Wagner, S. (2020):
Characterization of tire and road wear particles from road runoff indicates highly dynamic particle properties
Water Res. 185 , art. 116262 10.1016/j.watres.2020.116262 - Leppert, B., Strunz, S., Seiwert, B., Schlittenbauer, L., Schlichting, R., Pfeifer, C., Röder, S., Bauer, M., Borte, M., Stangl, G.I., Schöneberg, T., Schulz, A., Karkossa, I., Rolle-Kampczyk, U.E., Thürmann, L., von Bergen, M., Escher, B.I., Junge, K.M., Reemtsma, T., Lehmann, I., Polte, T. (2020):
Maternal paraben exposure triggers childhood overweight development
Nat. Commun. 11 , art. 561 10.1038/s41467-019-14202-1 - Seiwert, B., Klöckner, P., Wagner, S., Reemtsma, T. (2020):
Source-related smart suspect screening in the aqueous environment: search for tire-derived persistent and mobile trace organic contaminants in surface waters
Anal. Bioanal. Chem. 412 (20), 4909 - 4919 10.1007/s00216-020-02653-1
2019 (3)
- Alhelou, R., Seiwert, B., Reemtsma, T. (2019):
Hexamethoxymethylmelamine – A precursor of persistent and mobile contaminants in municipal wastewater and the water cycle
Water Res. 165 , art. 114973 10.1016/j.watres.2019.114973 - Kleinsteuber, S., Rohwerder, T., Lohse, U., Seiwert, B., Reemtsma, T. (2019):
Sated by a zero-calorie sweetener: Wastewater bacteria can feed on acesulfame
Front. Microbiol. 10 , art. 2606 10.3389/fmicb.2019.02606 - Wagner, S., Klöckner, P., Stier, B., Römer, M., Seiwert, B., Reemtsma, T., Schmidt, C. (2019):
Relationship between discharge and river plastic concentrations in a rural and an urban catchment
Environ. Sci. Technol. 53 (17), 10082 - 10091 10.1021/acs.est.9b03048
2018 (3)
- Bittner, L., Teixido, E., Seiwert, B., Escher, B.I., Klüver, N. (2018):
Influence of pH on the uptake and toxicity of β-blockers in embryos of zebrafish, Danio rerio
Aquat. Toxicol. 201 , 129 - 137 10.1016/j.aquatox.2018.05.020 - Jahangiri, E., Thomas, I., Schulze, A., Seiwert, B., Cabana, H., Schlosser, D. (2018):
Characterisation of electron beam irradiation-immobilised laccase for application in wastewater treatment
Sci. Total Environ. 624 , 309 - 322 10.1016/j.scitotenv.2017.12.127 - Karpov, M., Seiwert, B., Mordehay, V., Reemtsma, T., Polubesova, T., Chefetz, B. (2018):
Transformation of oxytetracycline by redox-active Fe(III)- and Mn(IV)-containing minerals: Processes and mechanisms
Water Res. 145 , 136 - 145 10.1016/j.watres.2018.08.015
2017 (6)
- Jahangiri, E., Seiwert, B., Reemtsma, T., Schlosser, D. (2017):
Laccase- and electrochemically mediated conversion of triclosan: Metabolite formation and influence on antibacterial activity
Chemosphere 168 , 549 - 558 10.1016/j.chemosphere.2016.11.030 - Krueger, M.C., Seiwert, B., Prager, A., Zhang, S., Abel, B., Harms, H., Schlosser, D. (2017):
Degradation of polystyrene and selected analogues by biological Fenton chemistry approaches: opportunities and limitations
Chemosphere 173 , 520 - 528 10.1016/j.chemosphere.2017.01.089 - Kühnert, A., Vogs, C., Seiwert, B., Aulhorn, S., Altenburger, R., Hollert, H., Küster, E., Busch, W. (2017):
Biotransformation in the zebrafish embryo – temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[a]anthracene
Environ. Pollut. 230 , 1 - 11 10.1016/j.envpol.2017.04.083 - Raeke, J., Lechtenfeld, O.J., Seiwert, B., Meier, T., Riemenschneider, C., Reemtsma, T. (2017):
Photochemically induced bound residue formation of carbamazepine with dissolved organic matter
Environ. Sci. Technol. 51 (10), 5523 - 5530 10.1021/acs.est.7b00823 - Riemenschneider, C., Seiwert, B., Goldstein, M., Al-Raggad, M., Salameh, E., Chefetz, B., Reemtsma, T. (2017):
An LC-MS/MS method for the determination of 28 polar environmental contaminants and metabolites in vegetables irrigated with treated municipal wastewater
Anal. Methods 9 (8), 1273 - 1281 10.1039/c6ay02984a - Riemenschneider, C., Seiwert, B., Moeder, M., Schwarz, D., Reemtsma, T. (2017):
Extensive transformation of the pharmaceutical carbamazepine following uptake into intact tomato plants
Environ. Sci. Technol. 51 (11), 6100 - 6109 10.1021/acs.est.6b06485
2016 (10)
- Brox, S., Seiwert, B., Haase, N., Küster, E., Reemtsma, T. (2016):
Metabolism of clofibric acid in zebrafish embryos (Danio rerio) as determined by liquid chromatography–high resolution–mass spectrometry
Comp. Biochem. Physiol. C-Toxicol. Pharmacol. 185–186 , 20 - 28 10.1016/j.cbpc.2016.02.007 - Brox, S., Seiwert, B., Küster, E., Reemtsma, T. (2016):
Toxicokinetics of polar chemicals in zebrafish embryo (Danio rerio): Influence of physicochemical properties and of niological processes
Environ. Sci. Technol. 50 (18), 10264 - 10272 10.1021/acs.est.6b04325 - Hirte, K., Seiwert, B., Schüürmann, G., Reemtsma, T. (2016):
New hydrolysis products of the beta-lactam antibiotic amoxicillin, their pH-dependent formation and search in municipal wastewater
Water Res. 88 , 880 - 888 10.1016/j.watres.2015.11.028 - König, A., Weidauer, C., Seiwert, B., Reemtsma, T., Unger, T., Jekel, M. (2016):
Reductive transformation of carbamazepine by abiotic and biotic processes
Water Res. 101 , 272 - 280 10.1016/j.watres.2016.05.084 - Matzrafi, M., Seiwert, B., Reemtsma, T., Rubin, B., Peleg, Z. (2016):
Climate change increases the risk of herbicide-resistant weeds due to enhanced detoxification
Planta 244 (6), 1217 - 1227 10.1007/s00425-016-2577-4 - Riemenschneider, C., Al-Raggad, M., Moeder, M., Seiwert, B., Salameh, E., Reemtsma, T. (2016):
Pharmaceuticals, their metabolites, and other polar pollutants in field-grown vegetables irrigated with treated municipal wastewater
J. Agric. Food Chem. 64 (29), 5784 - 5792 10.1021/acs.jafc.6b01696 - Schlittenbauer, L., Seiwert, B., Reemtsma, T. (2016):
Ultrasound-assisted hydrolysis of conjugated parabens in human urine and their determination by UPLC–MS/MS and UPLC–HRMS
Anal. Bioanal. Chem. 408 (6), 1573 - 1583 10.1007/s00216-015-9265-2 - Schlittenbauer, L., Seiwert, B., Reemtsma, T. (2016):
A false positive finding in liquid chromatography/triple quadrupole mass spectrometry analysis by a non-isobaric matrix component: the case of benzotriazole in urine for human biomonitoring
Rapid Commun. Mass Spectrom. 30 (13), 1560 - 1566 10.1002/rcm.7588 - Wang, S., Seiwert, B., Kästner, M., Miltner, A., Schäffer, A., Reemtsma, T., Yang, Q., Nowak, K.M. (2016):
(Bio)degradation of glyphosate in water-sediment microcosms – A stable isotope co-labeling approach
Water Res. 99 , 91 - 100 10.1016/j.watres.2016.04.041 - Weidauer, C., Davis, C., Raeke, J., Seiwert, B., Reemtsma, T. (2016):
Sunlight photolysis of benzotriazoles – Identification of transformation products and pathways
Chemosphere 154 , 416 - 424 10.1016/j.chemosphere.2016.03.090
2015 (4)
- Golan-Rozen, N., Seiwert, B., Riemenschneider, C., Reemtsma, T., Chefetz, B., Hadar, Y. (2015):
Transformation pathways of the recalcitrant pharmaceutical compound carbamazepine by the white-rot fungus Pleurotus ostreatus: Effects of growth conditions
Environ. Sci. Technol. 49 (20), 12351 - 12362 10.1021/acs.est.5b02222 - Schlittenbauer, L., Seiwert, B., Reemtsma, T. (2015):
Matrix effects in human urine analysis using multi-targeted liquid chromatography-tandem mass spectrometry
J. Chromatogr. A 1415 , 91 - 99 10.1016/j.chroma.2015.08.069 - Seiwert, B., Golan-Rozen, N., Weidauer, C., Riemenschneider, C., Chefetz, B., Hadar, Y., Reemtsma, T. (2015):
Electrochemistry combined with LC–HRMS: Elucidating transformation products of the recalcitrant pharmaceutical compound carbamazepine generated by the white-rot fungus Pleurotus ostreatus
Environ. Sci. Technol. 49 (20), 12342 - 12350 10.1021/acs.est.5b02229 - Yang, C., Kublik, A., Weidauer, C., Seiwert, B., Adrian, L. (2015):
Reductive dehalogenation of oligocyclic phenolic bromoaromatics by Dehalococcoides mccartyi strain CBDB1
Environ. Sci. Technol. 49 (14), 8497– - 8505 10.1021/acs.est.5b01401
2014 (2)
- Hübner, U., Seiwert, B., Reemtsma, T., Jekel, M. (2014):
Ozonation products of carbamazepine and their removal from secondary effluents by soil aquifer treatment – Indications from column experiments
Water Res. 49 , 34 - 43 10.1016/j.watres.2013.11.016 - Macherius, A., Seiwert, B., Schröder, P., Huber, C., Lorenz, W., Reemtsma, T. (2014):
Identification of plant metabolites of environmental contaminants by UPLC-QToF-MS: the in vitro metabolism of triclosan in horseradish
J. Agric. Food Chem. 62 (5), 1001 - 1009 10.1021/jf404784q