Dr. Bettina Seiwert

Scientist (Post-Doc)


Helmholtz-Center for Environmental Research - UFZ
Department Analytik
Permoserstr. 15
04318 Leipzig, Germany

phone: 0341 235  1394
Fax:     0341 235 1443

Research Interest

  • Generation and mass spectrometric identification of transformation products of organic chemicals
  • Mass spectrometric investigations and quantification of anthropogenic pollutants in water and urine

Curriculum Vitae

since 01/2012

09/2007 - 06/2009

08/2003 - 07/2007

07/2001 – 10/2001

10/1998 - 05/2003

Helmholtz Centre for Environmental Research, Post-Doc at the Department of Analytics

MPI of Molecular Plant Physiology, Golm, Research Group: Prof. Dr. L. Willmitzer, PostDoc 

University of Twente, Enschede, The Netherlands, Research group: U. Karst, PhD thesis: "Ferrocene-based derivatizing agents for LC/MS and LC/EC/MS"

ERASMUS-internship at “Micro and Trace Analysis Center” in Antwerp (Belgium), University Antwerp (UIA) Research Group: Prof. Dr. F. Adams
Focus of activities: LC/ICP-MS of metallothioneins

Study of chemistry, University of Leipzig Diploma thesis : „Untersuchung nichtkovalenter
Protein-Liganden-Wechselwirkung mit ESI-FT-ICR-MS“ Research group: Prof. S. Berger


T. Degenkolbe; P. Giavalisco; E. Zuther.; B. Seiwert.; D. Hincha., L. Willmitzer, Differential remodeling of the lipidome during cold acclimation in natural accessions of Arabidopsis thaliana, Plant J., accepted for publication

S. Kretzing, G. Abraham, B. Seiwert, F. R. Ungemach, U. Krügel, J. Teichert, R. Regenthal, In vivo assessment of antiemetic drugs and mechanism of lycorine-induced nausea and emesis, Arch. Toxicol., 2011,: 85, 12, 1565-1573

A. Burgos, J. Szymanski; B Seiwert, T. Degenkolbe, M. A. Hannah, P. Giavalisco, L Willmitzer Analysis of short-term changes in the Arabidopsis thaliana glycerolipidome in response to temperature and light, Plant J.L, 2011, 66, 4, 656-668

S. Kretzing, G. Abraham, B. Seiwert, F. R. Ungemach, U. Krugel, R. Regenthal, Dose-dependent emetic effects of the Amaryllidaceous alkaloid lycorine in beagle dogs , Toxicon, 2011, 57, 1, 117-124

P. Giavalisco, K. Köhl, J. Hummel, B. Seiwert, L.Willmitzer, 13C Isotope-Labeled Metabolomes Allowing for Improved Compound Annotation and Relative Quantification in Liquid Chromatography-Mass Spectrometry-based Metabolomic Research, Anal. Chem. 2009, 81, 6546–6551

S. Kierszniowska, B. Seiwert, W. X. Schulze, Definition of Arabidopsis sterol-rich membrane microdomains by differential treatment with methyl-ss-cyclodextrin and quantitative proteomics, Mol Cell Proteomics. 2009, 8, 612-623

S. Bomke, B. Seiwert, L. Dudek, S. Effkemann, U. Karst, Liquid chromatography/mass spectrometry method for the determination of biogenic amines in food samples, Anal. Bioanal. Chem., 2009, 393, 247-256

B. Seiwert, H. Hayen, U. Karst, Differential labeling of free and disulfide-bound thiol functions in proteins, J. Am. Soc. Mass Spectrom., 2008, 19, 1-7

B. Seiwert, U. Karst, Analysis of Cysteine-Containing Proteins Using Pre-Column Derivatization with N-(2-Ferroceneethyl)maleimide and Liquid Chromatography/Electrochemistry/Mass Spectrometry, Anal. Bioanal. Chem., 2007, 1633-1642

B. Seiwert, U. Karst, Simultaneous LC/MS/MS Determination of Thiols and Disulfides in Urine Samples Based on Differential Labeling with Ferrocene-Based Maleimides, Anal. Chem. 2007, 79, 7131–7138

M. Vogel; S. van Leeuwe; B. Seiwert; U. Karst, Analysing unpolar substances with LC/Electrochemistry/MS, NACHRICHTEN AUS DER CHEMIE, 2005, 53, 11, 1145-1147

K. Pagel, K. Seeger, B. Seiwert, A. Villa, A. E. Mark, S. Berger, B. Koksch, Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide, Org. Biomol. Chem., 2005, 3, 1189 - 1194

B. Seiwert, H. Henneken, U. Karst, Ferrocenoyl Piperazide as Derivatizing Agent for the Analysis of Isocyanates and Related Compounds Using Liquid Chromatography/Electro-chemistry/Mass Spectrometry (LC/EC/MS), J. Am. Soc. Mass Spectrom. 2004, 15, 1727-1736

H. Goenaga Infante, B. Seiwert, F. C. Adams, Capabilities of Surfactant-modifies High-Performance Liquid Chromatography for Fractions of Mammalian Metallothioneins, Chromatographia 2002, 56, 553-557

Book chapter

B. Seiwert, P. Giavalisco, L. Willmitzer, 2010, Chapter 20: Advanced Mass Spectrometry Methods for Analysis of Lipids from Photosynthetic Organisms in H. Wada, N. Murata (Eds.) Lipids in Photosynthesis (pp. 445-461) Springer Netherlands