Paul Bolay
Contact
Paul Bolay
Postdoc
Department of Microbial Biotechnology
Helmholtz Centre for
Environmental Research - UFZ
Permoserstr. 15, 04318 Leipzig
Tel: 0341 6025 2242
Fax: 0341 6025 2791
paul.bolay@ufz.de
CV / Scientific Career
2025-
Guest scientist
Department of Microbial Biotechnology
UFZ Leipzig
2022-2026
Postdoctoral researcher
Ångström laboratory, Uppsala University, Sweden
2018-2022
PhD student
UFZ Leipzig, Department of Solar Materials
2015-2018
M. Sc. Biochemistry and Biophysics
Albert-Ludwigs Universtiät, Freiburg i. Br.
2012-2015
B. Sc. Biology
Albert-Ludwigs Universtiät, Freiburg i. Br.
Publications
Bolay P, Janssen KN, Timm S, Hagemann M, Lindberg P. Engineering primary metabolism for sustainable production of isoprene in Synechocystis sp. PCC 6803. Microb Cell Fact. 2026 Jun 5;25(1):142.
Becker NS, Hufnagel F, Bolay P, Otec K, Orthwein T, Kulik A, Fink P, Lenz C, Lindberg P, Forchhammer K, Klähn S. Conversion of CO2 into valuable products: engineering the PirC-PGAM switch in cyanobacteria to direct carbon flux into desired products. Microb Cell Fact. 2026 May 20;25(1):128.
Janssen KN, Bolay P, Tüllinghoff A, Toepel J, Spindler D, Bühler B, Lindberg P. Engineering Cyanobacteria for High-Yield Photosynthetic Isoprene Production With Long-Term Phenotypic Stability. Plant Biotechnol J. 2026 Mar;24(3):1014-1030.
Bolay P, Toepel J, Bühler B. Biotechnological Applications of
Cyanobacteria: Synechocystis and Synechococcus Strains. Adv Biochem Eng
Biotechnol. 2025;192:155-191.
Bolay P, Dodge N, Janssen K, Jensen PE, Lindberg P. Tailoring regulatory components for metabolic engineering in cyanobacteria. Physiol Plant. 2024 May-Jun;176(3):e14316.
Bolay P, Hemm L, Florencio FJ, Hess WR, Muro-Pastor MI, Klähn S. The sRNA NsiR4 fine-tunes arginine synthesis in the cyanobacterium Synechocystis sp. PCC 6803 by post-transcriptional regulation of PirA. RNA Biol. 2022 Jan;19(1):811-818.
Bolay P, Schlüter S, Grimm S, Riediger M, Hess WR, Klähn S. The transcriptional regulator RbcR controls ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) genes in the cyanobacterium Synechocystis sp. PCC 6803. New Phytol. 2022 Jul;235(2):432-445.
Lupacchini S, Appel J, Stauder R, Bolay P, Klähn S, Lettau E, Adrian L, Lauterbach L, Bühler B, Schmid A, Toepel J. Rewiring cyanobacterial photosynthesis by the implementation of an oxygen-tolerant hydrogenase. Metab Eng. 2021 Nov;68:199-209.
Bolay P, Rozbeh R, Muro-Pastor MI, Timm S, Hagemann M, Florencio FJ, Forchhammer K, Klähn S. The Novel PII-Interacting Protein PirA Controls Flux into the Cyanobacterial Ornithine-Ammonia Cycle. mBio. 2021 Mar 23;12(2):e00229-21. doi: 10.1128/mBio.00229-21. PMID: 33758091; PMCID: PMC8092223.
Bolay P, Muro-Pastor MI, Florencio FJ, Klähn S. The Distinctive Regulation of Cyanobacterial Glutamine Synthetase. Life (Basel). 2018 Oct 27;8(4):52. doi: 10.3390/life8040052. PMID: 30373240; PMCID: PMC6316151.