Martin Lohse

Ph.D. student

Contact / Address

Martin Lohse
Helmholtz-Centre for Environmental Research – UFZ
Department Analytical Chemistry
Permoserstr. 15
DE-04318 Leipzig
Germany
Building 4.0, Room 410
Phone: 0341 235 1417

Current Research Project

molebird_ANA

My Ph.D. project is part of an interdisciplinary research consortium in the DFG funded priority program Rhizosphere Spatiotemporal Organisation - a Key to Rhizosphere Functions (SPP2089). In this consortium, research groups from various disciplines, such as soil physics, soil chemistry, plant physiology, microbiology, and modeling collaborate to analyze the function and development of the region of soil that is directly influenced by the root (rhizosphere). The aim is to identify spatiotemporal patterns in the rhizosphere and to understand the mechanisms responsible for rhizosphere functions.

In the project MoleBIRD, I am characterizing carbon dynamics in the rhizosphere. I want to understand how root-originated organic compounds shape the composition of the soil organic matter (SOM) pool and which parameters influence this complex mixture. I apply ultra-high resolution mass spectrometry (FT-ICR-MS) to analyze the small scale processes in the rhizosphere.

I work on the development of analytical methods in the research group BioGeoOmics (Department Analytical Chemistry). To unravel molecular gradients in soil new techniques with high specificity and sensitivity are needed.

Scheme of the proposed ultra-high resolution mass spectrometry workflow.
Scheme of the proposed ultra-high resolution mass spectrometry workflow.

Curriculum Vitae

since 2018 Ph.D. student, Department of Analytical Chemistry, Helmholtz Centre for Environmental Research
2016-2018 Master of Science in Chemistry, Leipzig University,
Master’s thesis at the Helmholtz Centre for Environmental Research: "Single cell analysis by high resolution mass spectrometry"
2012-2016 Bachelor of Science in Chemistry, Hochschule Zittau/Görlitz – University of Applied Sciences,
Bachelor’s thesis at the Helmholtz-Centre Dresden-Rossendorf: "Synthesis of lysine-derived inhibitors of transglutaminase 2 as potential radiotracers for the functional characterization of this enzyme"
2011-2012 Employee Quality Management, State Reservoir Administration of Saxony
2011 Chemical Laboratory Assistant, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft
2007-2011 Vocational training Chemical Laboratory Assistant, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft

Publications

2021 (1)

2020 (2)

2019 (1)

Publication without UFZ-affiliation

  • Wodtke, R., Hauser, C., Ruiz-Gómez, G., Jäckel, E., Bauer, D., Lohse, M., Wong, A., Pufe, J., Ludwig, F.-A., Fischer, S., Hauser, S., Greif, D., Pisabarro, M.T., Pietzsch, J., Pietsch, M., Löser, R., (2018):

    Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling. J. Med. Chem. 61 (10), 4528–4560  full text (doi)