Contact / Address
Current Research Project
My Ph.D. project is part of an interdisciplinary research consortium in the DFG funded priority program Rhizosphere Spatiotemporal Organisation - a Key to Rhizosphere Functions (SPP2089). In this consortium, research groups from various disciplines, such as soil physics, soil chemistry, plant physiology, microbiology, and modeling collaborate to analyze the function and development of the region of soil that is directly influenced by the root (rhizosphere). The aim is to identify spatiotemporal patterns in the rhizosphere and to understand the mechanisms responsible for rhizosphere functions.
In the project MoleBIRD, I am characterizing carbon dynamics in the rhizosphere. I want to understand how root-originated organic compounds shape the composition of the soil organic matter (SOM) pool and which parameters influence this complex mixture. I apply ultra-high resolution mass spectrometry (FT-ICR-MS) to analyze the small scale processes in the rhizosphere.
I work on the development of analytical methods in the research group BioGeoOmics (Department Analytical Chemistry). To unravel molecular gradients in soil new techniques with high specificity and sensitivity are needed.
Ph.D. student, Department of Analytical Chemistry, Helmholtz Centre for Environmental Research
Master of Science in Chemistry, Leipzig University,
Master’s thesis at the Helmholtz Centre for Environmental Research: "Single cell analysis by high resolution mass spectrometry"
Bachelor of Science in Chemistry, Hochschule Zittau/Görlitz – University of Applied Sciences,
Bachelor’s thesis at the Helmholtz-Centre Dresden-Rossendorf: "Synthesis of lysine-derived inhibitors of transglutaminase 2 as potential radiotracers for the functional characterization of this enzyme"
|2011-2012||Employee Quality Management, State Reservoir Administration of Saxony|
|2011||Chemical Laboratory Assistant, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft|
|2007-2011||Vocational training Chemical Laboratory Assistant, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft|
Publication without UFZ-affiliation
- Wodtke, R., Hauser, C., Ruiz-Gómez, G., Jäckel, E., Bauer, D., Lohse, M., Wong, A., Pufe, J., Ludwig, F.-A., Fischer, S., Hauser, S., Greif, D., Pisabarro, M.T., Pietzsch, J., Pietsch, M., Löser, R., (2018):
Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling. J. Med. Chem. 61 (10), 4528–4560 full text (doi)