Martin Lohse
Ph.D. student
Contact / Address
Department Analytical Chemistry
Permoserstr. 15
DE-04318 Leipzig
Germany
Building 4.0, Room 410
Phone: 0341 235 1417
ORCiD 0000-0003-2170-9476
ResearchGateCurrent Research Project
My Ph.D. project is part of an interdisciplinary research consortium in the DFG funded priority program Rhizosphere Spatiotemporal Organisation - a Key to Rhizosphere Functions (SPP2089). In this consortium, research groups from various disciplines, such as soil physics, soil chemistry, plant physiology, microbiology, and modeling collaborate to analyze the function and development of the region of soil that is directly influenced by the root (rhizosphere). The aim is to identify spatiotemporal patterns in the rhizosphere and to understand the mechanisms responsible for rhizosphere functions.
In the project MoleBIRD, I am characterizing carbon dynamics in the rhizosphere. I want to understand how root-originated organic compounds shape the composition of the soil organic matter (SOM) pool and which parameters influence this complex mixture. I apply ultra-high resolution mass spectrometry (FT-ICR-MS) to analyze the small scale processes in the rhizosphere.
I work on the development of analytical methods in the research group BioGeoOmics (Department Analytical Chemistry). To unravel molecular gradients in soil new techniques with high specificity and sensitivity are needed.
.png "Scheme of the proposed ultra-high resolution mass spectrometry workflow.")
Curriculum Vitae
| since 2018 |
Ph.D. student, Department of Analytical Chemistry, Helmholtz Centre for Environmental Research |
| 2016-2018 |
Master of Science in Chemistry, Leipzig University, Master’s thesis at the Helmholtz Centre for Environmental Research: "Single cell analysis by high resolution mass spectrometry" |
| 2012-2016 |
Bachelor of Science in Chemistry, Hochschule Zittau/Görlitz – University of Applied Sciences, Bachelor’s thesis at the Helmholtz-Centre Dresden-Rossendorf: "Synthesis of lysine-derived inhibitors of transglutaminase 2 as potential radiotracers for the functional characterization of this enzyme" |
| 2011-2012 | Employee Quality Management, State Reservoir Administration of Saxony |
| 2011 | Chemical Laboratory Assistant, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft |
| 2007-2011 | Vocational training Chemical Laboratory Assistant, Staatliche Betriebsgesellschaft für Umwelt und Landwirtschaft |
Publications
2023 (2)
- Han, L., Lohse, M., Nihemaiti, M., Reemtsma, T., Lechtenfeld, O.J. (2023):
Direct non-target analysis of dissolved organic matter and disinfection by-products in drinking water
with nano-LC-FT-ICR-MS
Environ. Sci.-Wat. Res. Technol. 9 (6), 1729 - 1737 10.1039/D3EW00097D - Lohse, M., Santangeli, M., Steininger-Mairinger, T., Oburger, E., Reemtsma, T., Lechtenfeld, O.J., Hann, S. (2023):
The effect of root hairs on exudate composition: a comparative non-targeted metabolomics approach
Anal. Bioanal. Chem. 415 (5), 823 - 840 10.1007/s00216-022-04475-9
2021 (1)
- Lohse, M., Haag, R., Lippold, E., Vetterlein, D., Reemtsma, T., Lechtenfeld, O.J. (2021):
Direct imaging of plant metabolites in the rhizosphere using laser desorption ionization ultra-high resolution mass spectrometry
Front. Plant Sci. 12 , art. 753812 10.3389/fpls.2021.753812
2020 (2)
- Lohse, M., Blaser, S.R.G.A., Vetterlein, D., Schlüter, S., Oburger, E., Reemtsma, T., Lechtenfeld, O.J. (2020):
Online nano solid phase extraction Fourier-transform ion cyclotron resonance mass spectrometry workflow to analyze small scale gradients of soil solution organic matter in the rhizosphere
Anal. Chem. 92 (15), 10442 - 10449 10.1021/acs.analchem.0c00946 - Lohse, M., Dusny, C., Kaesler, J., Lechtenfeld, O.J. (2020):
MRMS powered single cell metabolomics – Quantification of picogram amounts of a biocatalytic product from few living cells
Bruker Daltonics, 10.5281/zenodo.3947765
2019 (1)
- Dusny, C., Lohse, M., Reemtsma, T., Schmid, A., Lechtenfeld, O.J. (2019):
Quantifying a biocatalytic product from a few living microbial cells using microfluidic cultivation coupled to FT-ICR-MS
Anal. Chem. 91 (11), 7012 - 7018 10.1021/acs.analchem.9b00978
Publication without UFZ-affiliation
- Wodtke, R., Hauser, C., Ruiz-Gómez, G., Jäckel, E., Bauer, D., Lohse, M., Wong, A., Pufe, J., Ludwig, F.-A., Fischer, S., Hauser, S., Greif, D., Pisabarro, M.T., Pietzsch, J., Pietsch, M., Löser, R., (2018):
Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling. J. Med. Chem. 61 (10), 4528–4560 full text (doi)