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Foto: Manfred Schrewe

Dr. Manfred Schrewe


Resume

Manfred Schrewe, born 1978 in Paderborn (Germany), is a PostDoc in the research group Applied Biocatalysis.

After training as a biological technical assistant at the vocational college of the Hochsauerlandkreis in Olsberg he studied Molecular Biotechnology at the University of Bielefeld (2001-2006). In his diploma thesis at the Chair of Fermentation Engineering of Prof. E. Flaschel he worked on the improvement of recombinant protein production by means of process and genetic engineering. During his internship at the Department of Bioprocess Technology of Prof. S.O. Enfors at the Royal Institute of Technology (KTH), Stockholm, Sweden, he assisted in the development of a fingerprint method to characterize bacteria using SPR.

From March 2007 till June 2013, Manfred carried out his PhD thesis at the Laboratory of Chemical Biotechnology under supervision of Prof. A. Schmid and Dr. B. Bühler. In his research, he focused on whole-cell biocatalysis for the oxyfunctionalization of hydrocarbons. His thesis is entitled "Synthetic pathway and process engineering for terminal oxy- and aminofunctionalization via multistep biocatalysis in living microbial cells".

Next to the ongoing research on the production of functionalized hydrocarbons with whole cells, in his PostDoc project Manfred focuses on hydrogenase based catalysis for in vivo evolution of hydrogen and the utilization of H2 for cofactor regeneration, respectively.


Research Interests

  • Whole-cell biocatalysis
  • Photo-biocatalysis
  • Hydrogenase catalysis



CV / Scientific Career

01/2017 - 06/2017 Technician, Department of Solar Materials
Helmholtz Center for Environmental Research - UFZ, Leipzig
2014 - 2016 Scientist at the Department Solar Materials (SoMa), Helmholtz Center for Environmental Research, Leipzig, Germany
2013 - 2014 PostDoc at Laboratory of Chemical Biotechnology
TU Dortmund University, Germany
Research area: whole-cell biocatalysis for terminal functionalization of hydrocarbons
2007 - 2013 Dissertation at the Laboratory of Chemical Biotechnology
TU Dortmund University, Germany
PhD Thesis: ”Synthetic pathway and process engineering for terminal oxy- and aminofunctionalization via multistep biocatalysis in living microbial cells”
2001 - 2006 Studies in Molecular Biotechnology at Bielefeld University, Germany
Degree: Diplom Biotechnologe (Dipl. Biotech.)
Diploma Thesis at the Chair of Fermentation Technology: “Optimierung der Herstellung des DNA-bindenden Proteins RepU“
2004 - 2005 Project Thesis at the Division of Bioprocess Technology
Royal Institute of Technology, Stockholm, Sweden
Title: ”Characterization of particle surfaces using SPR“
1999 - 2001 Apprenticeship at Berufskolleg des Hochsauerlandkreises, Olsberg, Germany
Degree: Certified biological-technical assistant

Index:

2017 (1)
2016 (1)

You could use our publication index for further requests.

2017 (1)

  • Kadisch, M., Julsing, M.K., Schrewe, M., Jehmlich, N., Scheer, B., von Bergen, M., Schmid, A., Bühler, B., (2017):
    Maximization of cell viability rather than biocatalyst activity improves whole-cell ω-oxyfunctionalization performance
    Biotechnol. Bioeng. 114 (4), 874 - 884
    full text (url)
to index

2016 (1)

  • Ladkau, N., Assmann, M., Schrewe, M., Julsing, M.K., Schmid, A., Bühler, B., (2016):
    Efficient production of the Nylon 12 monomer ω-aminododecanoic acid methyl ester from renewable dodecanoic acid methyl ester with engineered Escherichia coli
    Metab. Eng. 36 , 1 - 9
    full text (url)
to index