Dr. Dana Kühnel
Address:
Permoserstr. 15
04318 Leipzig
Germany
Building: 6.0
Room: 230
Phone: +49 341 235 1515
Dr. Dana Kühnel
Curriculum Vitae
Dana Kühnel received her doctorate in the Department of Nutritional Toxicology of the University of Potsdam. Her doctoral thesis dealt with the development of colon cancer induced by polycyclic aromatic amines, formed during the heating of meat products. After finishing her PhD, in 2006 she joined the Department Cell Toxicology as a postdoctoral researcher (since 2009 the Department of Bioanalytical Ecotoxicology).
The focus of her research shifted to the assessment of potential (eco)toxicological effects of engineered nanomaterials. In several third-party funded projects (e.g. BMBF, EU-FP7, UBA), Dana tackled since then how technically produced nanomaterials affect the health of organisms, how they are internalized and distributed within organisms and how novel findings on nanomaterial-organism-interaction cans be communicated to outside the scientific world.
Specifically, the research activities focus on elucidating the influence of nanomaterial properties on the toxic outcome, the optimization and adaptation of test systems and protocols used in the risk assessment of chemicals for nanomaterials, and the development of analytical methods to gain qualitative and quantitative information on nanomaterial-organisms-interactions in a time- and space resolved manner. In addition, mixture effects between nanomaterials and chemicals are assessed. The outcomes of these activities feed into the development of risk assessment and grouping strategies for engineered nanomaterials.
Since 2009, Dana Kühnel also has been engaged in science communication by evaluating and summarizing scientific results dealing with the environmental impact of nanomaterials to a broad audience. This information is transported via the knowledgebase website www.nanoobjects.info. Starting in 2014, the research field on potential adverse of particles towards environmental organisms was expanded by including microplastic particles and aerosol particles into the research activities.
Current Projects
NanoRigo - Establishing a NANOtechnology RIsk Governance Framework; 01.01.2019 - 28.02.2023
InnoMatLife - Innovative materials and new production processes: Safety in the life cycle and industrial value creation; 01.04.2019 - 31.03.2022
DaNa4.0 - Data on new, innovative and safe application related materials; 01.03.2020 - 28.02.2023
PlasticsFatE - Plastics Fate and Effects in the human body; 01.04.2021 - 31.03.2025
Completed Projects
NanoValid - Development of reference methods for hazard identification, risk assessment and LCA of engineered nanomaterials
nanoGRAVUR – Nanostructured materials - grouping with regard to occupational safety, consumer and environmental protection and risk minimisation
GruppNano – Grouping of nanomaterials for a joint environmental impact assessment for regulatory aspects (UBA-UFO Plan Project)
FeNanosit - Iron-based nanoparticles and nanocomposite structures for removal of contaminants from groundwater and wastewater
DaNa - acquisition, evaluation and public-oriented presentation of society-relevant data and findings relating to nanomaterials
CNT-Membran - Nanoporous membranes of high specific flow from oriented CNTs for the energy-efficient treatment of waste and process water from the oil and gas industry; 01.03.2017 - 29.02.2020
DaNa2.0 - Data and knowledge on Nanomaterials - Processing of socially relevant scientific facts
WeatherMICS (JPI Oceans) - How weathering processes influence the transport, fate and toxicity of microplastics (MPs) and their leachates in the marine environment
Rapporting to the International expert meeting „OECD Horizontal Meeting on Eco-Toxicology and Environmental Fate of Nanomaterials“, OECD-WPMN / BMU / UBA
INOS - Identifizierung und Bewertung von Gesundheits- und Umweltauswirkungen von technischen nanoskaligen Partikeln; BMBF-Projekt; Arbeitspaket 4 / UFZ-Toxikologische Analyse von Nanopartikeln und Identifizierung von Wirkungsmechanismen
Publications
2023 (5)
- Jemec Kokalj, A., Heinlaan, M., Novak, S., Drobne, D., Kühnel, D. (2023):
Defining quality criteria for nanoplastic hazard evaluation: The case of polystyrene nanoplastics and aquatic invertebrate Daphnia spp.
Nanomaterials 13 (3), art. 536
full text (doi) - Kühnel, D., Mattern, A., Krug, H.F., Jemec Kokalj, A. (2023):
18 Human and environmental hazard of nanomaterials used in textiles
In: Cornier, J., Pursche, F. (eds.)
Particle Technology and Textiles: Review of Applications
De Gruyter, Berlin ; Boston, p. 343 - 372
full text (doi) - Mullins, M., Himly, M., Rodríguez Llopis, I., Furxhi, I., Hofer, S., Hofstätter, N., Wick, P., Romeo, D., Kühnel, D., Siivola, K., Catalán, J., Hund-Rinke, K., Xiarchos, I., Linehan, S., Schuurbiers, D., García Bilbao, A., Barruetabeña, L., Drobne, D. (2023):
(Re)Conceptualizing decision-making tools in a risk governance framework for emerging technologies—the case of nanomaterials
Environ. Syst. Decis. 43 (1), 3 - 15
full text (doi) - Nau, K., Espinoza, S., Krug, H.F., Marquardt, C., Mattern, A., Möller, N., Steinbach, C., Kühnel, D. (2023):
Knowledge Base Materials sustainable science communication on advanced materials
In: Scholz, S.G., Howlett, R.J., Setchi, R. (eds.)
Sustainable Design and Manufacturing. Proceedings of the 9th International Conference on Sustainable Design and Manufacturing (SDM 2022)
Smart Innovation, Systems and Technologies 338
Springer Nature, Singapore, p. 33 - 42
full text (doi) - Ramsperger, A.F.R.M., Bergamaschi, E., Panizzolo, M., Fenoglio, I., Barbero, F., Peters, R., Undas, A., Purker, S., Giese, B., Lalyer, C.R., Tamargo, A., Moreno-Arribas, M.V., Grossart, H.-P., Kühnel, D., Dietrich, J., Paulsen, F., Afanou, A.K., Zienolddiny-Narui, S., Eriksen Hammer, S., Kringlen Ervik, T., Graff, P., Brinchmann, B.C., Nordby, K.-C., Wallin, H., Nassi, M., Benetti, F., Zanella, M., Brehm, J., Kress, H., Löder, M.G.J., Laforsch, C. (2023):
Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans
NanoImpact 29 , art. 100441
full text (doi)
2022 (2)
- Hund-Rinke, K., Broßell, D., Eilebrecht, S., Schlich, K., Schlinkert, R., Steska, T., Wolf, C., Kühnel, D. (2022):
Prioritising nano- and microparticles: identification of physicochemical properties relevant for toxicity to Raphidocelis subcapitata and Daphnia magna
Environ. Sci. Eur. 34 , art. 116
full text (doi) - van Broekhuizen, P., Säämänen, A., Schuurbiers, D., Isigonis, P., Jensen, K.A., Kühnel, D., Le Blansch, K. (2022):
Tyre wear nanoparticles as test for a nano risk governance framework
Front. Environ. Sci. 10 , art. 1045246
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2021 (2)
- Arp, H.P.H., Kühnel, D., Rummel, C., MacLeod, M., Potthoff, A., Reichelt, S., Rojo-Nieto, E., Schmitt-Jansen, M., Sonnenberg, J., Toorman, E., Jahnke, A. (2021):
Weathering plastics as a planetary boundary threat: Exposure, fate, and hazards
Environ. Sci. Technol. 55 (11), 7246 - 7255
full text (doi) - Jemec Kokalj, A., Hartmann, N.B., Drobne, D., Potthoff, A., Kühnel, D. (2021):
Quality of nanoplastics and microplastics ecotoxicity studies: Refining quality criteria for nanomaterial studies
J. Hazard. Mater. 415 , art. 125751
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2020 (2)
- Hund-Rinke, K., Sinram, T., Schlich, K., Nickel, C., Dickehut, H.P., Schmidt, M., Kühnel, D. (2020):
Attachment efficiency of nanomaterials to algae as an important criterion for ecotoxicity and grouping
Nanomaterials 10 (6), art. 1021
full text (doi) - Mohaupt, V., Völker, J., Altenburger, R., Birk, S., Kirst, I., Kühnel, D., Küster, E., Semeradova, S., Šubelj, G. (2020):
Pesticides in European rivers, lakes and groundwaters – Data assessment
ETC/ICM Technical Report 1/2020
European Topic Centre on Inland, Coastal and Marine Waters, Helmholtz Centre for Environmental Research GmbH – UFZ, Magdeburg, 86 pp.
full text (url)
2019 (5)
- Jemec Kokalj, A., Kuehnel, D., Puntar, B., Žgajnar Gotvajn, A., Kalčikova, G. (2019):
An exploratory ecotoxicity study of primary microplastics versus aged in natural waters and wastewaters
Environ. Pollut. 254 , art. 112980
full text (doi) - Kühnel, D., Nickel, C., Hellack, B., van der Zalm, E., Kussatz, C., Herrchen, M., Meisterjahn, B., Hund-Rinke, K. (2019):
Closing gaps for environmental risk screening of engineered nanomaterials
NanoImpact 15 , art. 100173
full text (doi) - Schmidt, S., Altenburger, R., Kühnel, D. (2019):
From the air to the water phase: implication for toxicity testing of combustion-derived particles
Biomass Convers. Biorefinery 9 (1), 213 - 225
full text (doi) - Weil, M., Mackenzie, K., Foit, K., Kühnel, D., Busch, W., Bundschuh, M., Schulz, R., Duis, K. (2019):
Environmental risk or benefit? Comprehensive risk assessment of groundwater treated with nano Fe0-based Carbo-Iron®
Sci. Total Environ. 677 , 156 - 166
full text (doi) - Wohlleben, W., Hellack, B., Nickel, C., Herrchen, M., Hund-Rinke, K., Kettler, K., Riebeling, C., Haase, A., Funk, B., Kühnel, D., Göhler, D., Stintz, M., Schumacher, C., Wiemann, M., Keller, J., Landsiedel, R., Broßell, D., Pitzko, S., Kuhlbusch, T.A.J. (2019):
The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies
Nanoscale 11 (38), 17637 - 17654
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2018 (5)
- Hund-Rinke, K., Schlich, K., Kühnel, D., Hellack, B., Kaminski, H., Nickel, C. (2018):
Grouping concept for metal and metal oxide nanomaterials with regard to their ecotoxicological effects on algae, daphnids and fish embryos
NanoImpact 9 , 52 - 60
full text (doi) - Krug, H.F., Bohmer, N., Kühnel, D., Marquardt, C., Nau, K., Steinbach, C. (2018):
The DaNa2.0 Knowledge Base Nanomaterials—An important measure accompanying nanomaterials development
Nanomaterials 8 (4), art. 204
full text (doi) - Kühnel, D. (2018):
Chapter 9. Progress towards risk assessment for engineered nanomaterials
In: Dhawan, A., Anderson, D., Shanker, R. (eds.)
Nanotoxicology: Experimental and Computational Perspectives
Issues in Toxicology 35
Royal Society of Chemistry (RSC), Cambridge, p. 232 - 247
full text (doi) - Kühnel, D., Krug, H.F., Jemec Kokalj, A. (2018):
Environmental impacts of engineered nanomaterials—imbalances in the safety assessment of selected nanomaterials
Materials 11 (8), art. 1444
full text (doi) - Naasz, S., Altenburger, R., Kühnel, D. (2018):
Environmental mixtures of nanomaterials and chemicals: The Trojan-horse phenomenon and its relevance for ecotoxicity
Sci. Total Environ. 635 , 1170 - 1181
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2017 (6)
- Böhme, S., Baccaro, M., Schmidt, M., Potthoff, A., Stärk, H.-J., Reemtsma, T., Kühnel, D. (2017):
Metal uptake and distribution in the zebrafish (Danio rerio) embryo: differences between nanoparticles and metal ions
Environ. Sci.-Nano 4 (5), 1005 - 1015
full text (doi) - Kühnel, D., Marquardt, C., Nau, K., Krug, H.F., Paul, F., Steinbach, C. (2017):
Environmental benefits and concerns on safety: communicating latest results on nanotechnology safety research—the project DaNa2.0
Environ. Sci. Pollut. Res. 24 (12), 11120 - 11125
full text (doi) - Potthoff, A., Oelschlägel, K., Schmitt-Jansen, M., Rummel, C.D., Kühnel, D. (2017):
From the sea to the laboratory: Characterization of microplastic as prerequisite for the assessment of ecotoxicological impact
Integr. Environ. Assess. Manag. 13 (3), 500 - 504
full text (doi) - Ribeiro, A.R., Leite, P.E., Falagan-Lotsch, P., Benetti, F., Micheletti, C., Budtz, H.C., Jacobsen, N.R., Lisboa-Filho, P.N., Rocha, R.A., Kühnel, D., Hristozov, D., Granjeiro, J.M. (2017):
Challenges on the toxicological predictions of engineered nanoparticles
NanoImpact 8 , 59 - 72
full text (doi) - Rummel, C.D., Jahnke, A., Gorokhova, E., Kühnel, D., Schmitt-Jansen, M. (2017):
Impacts of biofilm formation on the fate and potential effects of microplastic in the aquatic environment
Environ. Sci. Technol. Lett. 4 (7), 258 - 267
full text (doi) - Steinbach, C., Bohmer, N., Krug, H.F., Kühnel, D., Nau, K., Paul, F., Reithel, S., Marquardt, C. (2017):
DaNa 2.0 – verlässliche Informationen zur Sicherheit von marktüblichen Nanomaterialien. DaNa 2.0 – reliable information on the safety of commercially available nanomaterials
Chem. Ing. Tech. 89 (3), 232 - 238
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2016 (4)
- Heinlaan, M., Muna, M., Knöbel, M., Kistler, D., Odzak, N., Kühnel, D., Müller, J., Gupta, G.S., Kumar, A., Shanker, R., Sigg, L. (2016):
Natural water as the test medium for Ag and CuO nanoparticle hazard evaluation: An interlaboratory case study
Environ. Pollut. 216 , 689 - 699
full text (doi) - Jemec, A., Kahru, A., Potthoff, A., Drobne, D., Heinlaan, M., Böhme, S., Geppert, M., Novak, S., Schirmer, K., Rekulapally, R., Singh, S., Aruoja, V., Sihtmäe, M., Juganson, K., Käkinen, A., Kühnel, D. (2016):
An interlaboratory comparison of nanosilver characterisation and hazard identification: Harmonising techniques for high quality data
Environ. Int. 87 , 20 - 32
full text (doi) - Kos, M., Kahru, A., Drobne, D., Singh, S., Kalčíková, G., Kühnel, D., Rohit, R., Žgajnar Gotvajn, A., Jemec, A. (2016):
A case study to optimise and validate the brine shrimp Artemia franciscana immobilisation assay with silver nanoparticles: The role of harmonisation
Environ. Pollut. 213 , 173 - 183
full text (doi) - Nau, K., Bohmer, N., Kühnel, D., Marquardt, C., Paul, F., Steinbach, C., Krug, H.F. (2016):
The DaNa2.0 knowledge base on nanomaterials – Communicating current nanosafety research based on evaluated literature data
J. Mat. Educ. 38 (3-4), 93 - 108
2015 (5)
- Böhme, S., Kühnel, D., Stärk, H.-J., Reemtsma, T. (2015):
New developments in the field of the visualization of nanoparticle uptake by environmental organisms with LA-ICP-MS
In: Daus, B., Bings, N., Leopold, K., Otto, M., Panne, U., Welz, U., Wennrich, R. (eds.)
Canas ’15. Colloquium Analytische Atomspektroskopie, 8.–11. März 2015, Helmholtz-Zentrum für Umweltforschung – UFZ Leipzig. Colloquium Analytical Atomic Spectroscopy, 8–11 March, 2015, Helmholtz Centre for Environmental Research – UFZ Leipzig
Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, p. 61 - 62 - Böhme, S., Stärk, H.-J., Kühnel, D., Reemtsma, T. (2015):
Exploring LA-ICP-MS as a quantitative imaging technique to study nanoparticle uptake in Daphnia magna and zebrafish (Danio rerio) embryos
Anal. Bioanal. Chem. 407 (18), 5477 - 5485
full text (doi) - Böhme, S., Stärk, H.-J., Reemtsma, T., Kühnel, D. (2015):
Effect propagation after silver nanoparticle exposure in zebrafish (Danio rerio) embryos: a correlation to internal concentration and distribution patterns
Environ. Sci.-Nano 2 (6), 603 - 614
full text (doi) - Potthoff, A., Weil, M., Meißner, T., Kühnel, D. (2015):
Towards sensible toxicity testing for nanomaterials: proposal for the specification of test design
Sci. Technol. Adv. Mater. 16 (6), art. 065006
full text (doi) - Weil, M., Meißner, T., Busch, W., Springer, A., Kühnel, D., Schulz, R., Duis, K. (2015):
The oxidized state of the nanocomposite Carbo-Iron® causes no adverse effects on growth, survival and differential gene expression in zebrafish
Sci. Total Environ. 530-531 , 198 - 208
full text (doi)
2014 (6)
- Böhme, S., Stärk, H.-J., Meißner, T., Springer, A., Reemtsma, T., Kühnel, D., Busch, W. (2014):
Quantification of Al2O3 nanoparticles in human cell lines applying inductively coupled plasma mass spectrometry (neb-ICP-MS, LA-ICP-MS) and flow cytometry-based methods
J. Nanopart. Res. 16 , 2592
full text (doi) - Krug, H.F., Wick, P., Hirsch, C., Kühnel, D., Marquardt, C., Nau, K., Mathes, B., Steinbach, C. (2014):
Im Gleichgewicht? Risikoforschung zu Nanomaterialien : die internationale Risikodebatte zur Nanotechnologie und zu möglichen Vorsorgemaßnahmen für Arbeitsplatz und Verbraucher
Arbeitsmedizin, Sozialmedizin, Umweltmedizin : ASU 43 (1), 6 - 18 - Kühnel, D., Marquardt, C., Nau, K., Krug, H.F., Mathes, B., Steinbach, C. (2014):
Environmental impacts of nanomaterials: providing comprehensive information on exposure, transport and ecotoxicity - the project DaNa2.0
Environ. Sci. Eur. 26 , art. 21
full text (doi) - Kühnel, D., Nickel, C. (eds., 2014):
Ecotoxicology and environmental fate of manufactured nanomaterials: test guidelines
Series on the Safety of Manufactured Nanomaterials 40 - ENV/JM/MONO(2014)1
OECD Organisation for Economic Co-operation and Development, Paris, 84 pp.
full text (url) - Kühnel, D., Nickel, C. (2014):
The OECD expert meeting on ecotoxicology and environmental fate — towards the development of improved OECD guidelines for the testing of nanomaterials
Sci. Total Environ. 472 , 347 - 353
full text (doi) - Oomen, A.G., Bos, P.M.J., Fernandes, T.F., Hund-Rinke, K., Boraschi, D., Byrne, H.J., Aschberger, K., Gottardo, S., von der Kammer, F., Kühnel, D., Hristozov, D., Marcomini, A., Migliore, L., Scott-Fordsmand, J., Wick, P., Landsiedel, R. (2014):
Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10
Nanotoxicology 8 (3), 334 - 348
full text (doi)
2013 (3)
- Jackson, P., Jacobsen, N.R., Baun, A., Birkedal, R., Kühnel, D., Jensen, K.A., Vogel, U., Wallin, H. (2013):
Bioaccumulation and ecotoxicity of carbon nanotubes
Chem. Cent. J. 7 , 154
full text (doi) - Kroll, A., Kühnel, D., Schirmer, K. (2013):
Testing nanomaterial toxicity in unicellular eukaryotic algae and fish cell lines
In: Armstrong, D., Bharali, D.J. (eds.)
Oxidative stress and nanotechnology: methods and protocols
Methods in Molecular Biology 1028
Springer Nature, p. 165 - 195
full text (doi) - Marquardt, C., Kühnel, D., Richter, V., Krug, H.F., Mathes, B., Steinbach, C., Nau, K. (2013):
Latest research results on the effects of nanomaterials on humans and the environment: DaNa - Knowledge Base Nanomaterials
J. Phys.: Conf. Ser. 429 , 012060
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2012 (2)
- Kühnel, D., Scheffler, K., Wellner, P., Meißner, T., Potthoff, A., Busch, W., Springer, A., Schirmer, K. (2012):
Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro
J. Hazard. Mater. 227-228 , 418 - 426
full text (doi) - Steinbach, C., Mathes, B., Krug, H.F., Wiek, P., Kühnel, D. (2012):
Die Sicherheit von Nanomaterialien in der Diskussion
Deutsche Apotheker-Zeitung 152 (16), 90 - 92
2011 (1)
- Busch, W., Bastian, S., Trahorsch, U., Iwe, M., Kühnel, D., Meißner, T., Springer, A., Gelinsky, M., Richter, V., Ikonomidou, C., Potthoff, A., Lehmann, I., Schirmer, K. (2011):
Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties
J. Nanopart. Res. 13 (1), 293 - 310
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2010 (5)
- Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y. (2010):
Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
UWSF - Z. Umweltchem. Ökotox. 22 (4), 502 - 506
full text (doi) - Busch, W., Kühnel, D., Schirmer, K., Scholz, S. (2010):
Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes
BMC Genomics 11 , art. 65
full text (doi) - Hildebrand, H., Kühnel, D., Potthoff, A., Mackenzie, K., Springer, A., Schirmer, K. (2010):
Evaluating the cytotoxicity of palladium/magnetite nano-catalysts intended for wastewater treatment
Environ. Pollut. 158 (1), 65 - 73
full text (doi) - Meissner, T., Kühnel, D., Busch, W., Oswald, S., Richter, V., Michaelis, A., Schirmer, K., Potthoff, A. (2010):
Physical-chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations
Nanotoxicology 4 (2), 196 - 206
full text (doi) - Stärk, H.-J., Kühnel, D., Busch, W., Wellner, P., Schirmer, C. (2010):
Charakterisierung der Aufnahme von Wolframkarbid-Nanopartikeln durch Humanzellen mittels LA-ICP-MS
In: Otto, M., Bulska, E., Knapp, G., Schlemmer, G., Ullrich, A., Welz, B., Wennrich, R. (Hrsg.)
CANAS '09 - Colloquium Analytische Atomspektroskopie, 22.-25. März 2009, Freiberg
TU Bergakademie Freiberg, Institut für Analytische Chemie, Freiberg, S. 44 - 44
2009 (5)
- Bastian, S., Busch, W., Kühnel, D., Springer, A., Meißner, T., Holke, R., Scholz, S., Iwe, M., Pompe, W., Gelinsky, M., Potthoff, A., Richter, V., Ikonomidou, H., Schirmer, K. (2009):
Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro
Environ. Health Perspect. 117 (4), 530 - 536
full text (doi) - Busch, W., Kühnel, D., Springer, A., Meissner, T., Gelinsky, M., Potthoff, A., Scholz, S., Richter, V., Schirmer, K. (2009):
Tungsten carbide and tungsten carbide cobalt nanoparticle toxicity: The role of cellular particle uptake, leached ions and cobalt bioavailability
Toxicol. Lett. 189 (Suppl. 1), S185 - S185
full text (doi) - Kühnel, D., Busch, W., Meissner, T., Springer, A., Potthoff, A., Richter, V., Gelinsky, M., Scholz, S., Schirmer, K. (2009):
Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line
Aquat. Toxicol. 93 (2-3), 91 - 99
full text (doi) - Kühnel, D., Taugner, F., Scholtka, B., Steinberg, P. (2009):
Inflammation does not precede or accompany the induction of preneoplastic lesions in the colon of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-fed rats
Arch. Toxicol. 83 (8), 763 - 768
full text (doi) - Potthoff, A., Meißner, T., Richter, V., Busch, W., Kühnel, D., Bastian, S., Iwe, M., Springer, A. (2009):
Evaluation of health risks of nanoparticles - a contribution to a sustainable development of nanotechnology
In: Kny, E. (ed.)
Nanocomposite materials
Solid State Phenomena 151
Trans Tech Publications, Durnten-Zurich, p. 183 - 189
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2004 (2)
- Baumann, O., Kühnel, D., Dames, P., Walz, B. (2004):
Dopaminergic and serotonergic innervation of cockroach salivary glands: distribution and morphology of synapses and release sites
J. Exp. Biol. 207 (15), 2565 - 2575
full text (doi) - Kühnel, D., Steinberg, P., Scholtka, B. (2004):
A human-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) can induce precancerous lesions in rat intestine after 6 months of exposure
Naunyn-Schmiedebergs Arch. Pharmacol. 369 (Suppl. 1), R143
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