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Title (Primary) Evaluating the cytotoxicity of palladium/magnetite nano-catalysts intended for wastewater treatment
Author Hildebrand, H.; Kühnel, D.; Potthoff, A.; Mackenzie, K.; Springer, A.; Schirmer, K.;
Journal Environmental Pollution
Year 2010
Department BIOTOX; TUCHEM;
Volume 158
Issue 1
Language englisch;
Keywords Palladium-magnetite; Nano-catalysts; Magnetite; Cytotoxicity; ROS
Abstract Palladium/magnetite nanoparticulate catalysts were developed for efficient elimination of halogenated organic pollutants from contaminated wastewater. Particle recovery from treated water can be ensured via magnetic separation. However, in worst-case scenarios, this catalyst removal step might fail, leading to particle release into the environment. Therefore, a toxicological study was conducted to investigate the impact of both pure magnetite and palladium/magnetite nanoparticle exposure upon human skin (HaCaT) and human colon (CaCo-2) cell lines and a cell line from rainbow trout gills (RTgill-W1). To quantify cell viability after particle exposure, three endpoints were examined for all tested cell lines. Additionally, the formation of reactive oxygen species was studied for the human cells. The results showed only minor effects of the particles on the tested cell systems and support the assumption that palladium/magnetite nano-catalysts can be implemented for a new wastewater treatment technology in which advantageous catalyst properties outweigh the risks. Impact of nano-Pd/magnetite on cell viability was studied and appears to be low.
ID 10095
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=10095
Hildebrand, H., Kühnel, D., Potthoff, A., Mackenzie, K., Springer, A., Schirmer, K. (2010):
Evaluating the cytotoxicity of palladium/magnetite nano-catalysts intended for wastewater treatment
Environ. Pollut. 158 (1), 65 - 73