Dr. Dana Kühnel
Address:
Permoserstr. 15
04318 Leipzig
Germany
Building: 6.0
Room: 230
Phone: +49 341 6025 1515
Research Interests
- assessment of (eco)toxicological effects of anthropogenic particles: engineered nanomaterials, nano/microplastic, combustion derived particles, advanced/innovative materials
- Organism-particle interaction: assessment of attachment, internalisation and distribution of anthropogenic particles in environmental organisms
- Mixture effects of anthropogenic particles and auxiliary chemicals
- Science and Risk Communication on the environmental safety of anthropogenic particles (Knowledge Base Materials www.nanoobjects.info)
Curriculum Vitae
10/2021
Visiting scientist at the University of Ljubljana, Biotechnical Faculty, Nanobioteam, Ljublijana, Slovenia
Since 2016
Teaching: lectures for students of the “Postgraduate Studies in Toxicology and Environmental Protection”, University of Leipzig,
Since 2009
Scientist, Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research – UFZ, Leipzig
01/2006
Scientist, Department of Cell Toxicology, Helmholtz Centre for Environmental Research – UFZ, Leipzig
07/2001 - 03/2006
PhD-student/Scientist, University of Potsdam, Faculty of Mathematics and Natural Sciences, Institute of Nutritional Sciences, Department of Nutritional Toxicology
PhD thesis: “Histological and molecular genetic analysis of intestinal tissues of F344 rats exposed to the human-relevant carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)”
06/2001 - 10/2001
Student, Biology, University of Potsdam, Faculty of Mathematics and Natural Sciences, Institute for Biochemistry and Biology, Department Animal Physiology
Diploma thesis: “The Innervation of the Salivary gland of Periplaneta americana”
Current Projects
PlasticsFatE - Plastics Fate and Effects in the human body; 01.04.2021 - 31.03.2025
FaPlaN - Investigation of ecotoxicological effects of fibrous and platelet-shaped advanced materials for deriving adapted testing strategies; 01.09.2023 - 31.08.2026
MANTRA - Data on innovative materials for sustainability and transfer
(Accompanying project to the Material Hub Initiative MaterialNeutral - Resource sovereignty through material innovations); 01.01.2024 - 30.06.2028
Completed projects
NanoRigo - Establishing a NANOtechnology RIsk Governance Framework; 01.01.2019 - 28.02.2023
InnoMatLife - Innovative materials and new production processes: Safety in the life cycle and industrial value creation; 01.04.2019 - 31.03.2022
DaNa4.0 - Data on new, innovative and safe application related materials; 01.03.2020 - 28.02.2023
NanoValid - Development of reference methods for hazard identification, risk assessment and LCA of engineered nanomaterials
nanoGRAVUR – Nanostrukturierte Materialien – Gruppierung hinsichtlich Arbeits-, Verbraucher- und Umweltschutz und Risikominimierung
GruppNano – Gruppierung von Nanomaterialien im Hinblick auf eine gemeinsame Prüfung von Umweltwirkung für Regulierungsaspekte (UBA-UFO Plan Projekt)
FeNanosit - Iron-based nanoparticles and nanocomposite structures for removal of contaminants from groundwater and wastewater
DaNa - acquisition, evaluation and public-oriented presentation of society-relevant data and findings relating to nanomaterials
DaNa2.0 - Data and knowledge on Nanomaterials - Processing of socially relevant scientific facts
CNT-Membran - Nanoporöse Membranen hohen spezifischen Flusses aus orientierten CNTs für die energieeffiziente Aufbereitung von Ab- und Prozesswässern der Erdöl- und Erdgasindustrie; 01.03.2017 - 29.02.2020
WeatherMICS (JPI Oceans) - How weathering processes influence the transport, fate and toxicity of microplastics (MPs) and their leachates in the marine environment
Rapporting to the International expert meeting „OECD Horizontal Meeting on Eco-Toxicology and Environmental Fate of Nanomaterials“, OECD-WPMN / BMU / UBA
INOS - Identifizierung und Bewertung von Gesundheits- und Umweltauswirkungen von technischen nanoskaligen Partikeln; BMBF-Projekt; Arbeitspaket 4 / UFZ-Toxikologische Analyse von Nanopartikeln und Identifizierung von Wirkungsmechanismen
Publications
2024 (1)
- Steska, T., Wagner, S., Reemtsma, T., Kühnel, D. (2024):
Influence of silver fiber morphology on dose-response relationship and enrichment in Daphnia magna studied by elemental imaging with LA-ICP-TOF-MS
Chem. Res. Toxicol. 37 (2), 292 - 301 10.1021/acs.chemrestox.3c00293
2023 (10)
- Jemec, A., Kuehnel, D., Drobne, D., Zidar, P. (2023):
Behavioural response to microplastics: case study with woodlice and daphnids
Toxicol. Lett. 384 (Suppl. 1), S209 - S209 10.1016/S0378-4274(23)00758-0 - Jemec Kokalj, A., Heinlaan, M., Novak, S., Drobne, D., Kühnel, D. (2023):
Defining quality criteria for nanoplastic hazard evaluation: The case of polystyrene nanoplastics and aquatic invertebrate Daphnia spp.
Nanomaterials 13 (3), art. 536 10.3390/nano13030536 - Kuehnel, D. (2023):
Micro-and nano-plastics in our environment: presence and potential impact
Toxicol. Lett. 384 (Suppl. 1), S44 10.1016/S0378-4274(23)00376-4 - Kuehnel, D., Heinlaan, M., Novak, S., Drobne, D., Kokalj, A.J. (2023):
Study quality criteria for nanoplastics: a case study on polystyrene nanoplastics and the aquatic invertebrate Daphnia spp.
Toxicol. Lett. 384 (Suppl. 1), S208 - S208 10.1016/S0378-4274(23)00756-7 - Kühnel, D., Krug, H.F., Mattern, A., Jemec Kokalj, A. (2023):
Human and environmental hazard of nanomaterials used in textiles
In: Cornier, J., Pursche, F. (eds.)
Particle technology and textiles: Review of applications
De Gruyter STEM
De Gruyter, Berlin ; Boston, p. 343 - 372 10.1515/9783110670776-018 - Kühnel, D., Steska, T., Schlich, K., Wolf, C., Wohlleben, W., Hund-Rinke, K. (2023):
Polymers of low concern? Assessment of microplastic particles used in 3D printing regarding their toxicity on Raphidocelis subcapitata and Daphnia magna
Microplastics and Nanoplastics 3 , art. 29 10.1186/s43591-023-00078-y - Küster, E., Addo, G.G., Aulhorn, S., Kühnel, D. (2023):
Miniaturisation of the Daphnia magna immobilisation assay for the reliabletesting of low volume samples
UCL Open Environment Preprint 10.14324/111.444/000219.v1 - Mullins, M., Himly, M., Rodríguez Llopis, I., Furxhi, I., Hofer, S., Hofstätter, N., Wick, P., Romeo, D., Kühnel, D., Siivola, K., Catalán, J., Hund-Rinke, K., Xiarchos, I., Linehan, S., Schuurbiers, D., García Bilbao, A., Barruetabeña, L., Drobne, D. (2023):
(Re)Conceptualizing decision-making tools in a risk governance framework for emerging technologies—the case of nanomaterials
Environ. Syst. Decis. 43 (1), 3 - 15 10.1007/s10669-022-09870-2 - Nau, K., Espinoza, S., Krug, H.F., Marquardt, C., Mattern, A., Möller, N., Steinbach, C., Kühnel, D. (2023):
Knowledge Base Materials sustainable science communication on advanced materials
In: Scholz, S.G., Howlett, R.J., Setchi, R. (eds.)
Sustainable design and manufacturing. Proceedings of the 9th International Conference on Sustainable Design and Manufacturing (SDM 2022)
Smart Innovation, Systems and Technologies 338
Springer Nature, Singapore, p. 33 - 42 10.1007/978-981-19-9205-6_4 - Ramsperger, A.F.R.M., Bergamaschi, E., Panizzolo, M., Fenoglio, I., Barbero, F., Peters, R., Undas, A., Purker, S., Giese, B., Lalyer, C.R., Tamargo, A., Moreno-Arribas, M.V., Grossart, H.-P., Kühnel, D., Dietrich, J., Paulsen, F., Afanou, A.K., Zienolddiny-Narui, S., Eriksen Hammer, S., Kringlen Ervik, T., Graff, P., Brinchmann, B.C., Nordby, K.-C., Wallin, H., Nassi, M., Benetti, F., Zanella, M., Brehm, J., Kress, H., Löder, M.G.J., Laforsch, C. (2023):
Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans
NanoImpact 29 , art. 100441 10.1016/j.impact.2022.100441
2022 (2)
- Hund-Rinke, K., Broßell, D., Eilebrecht, S., Schlich, K., Schlinkert, R., Steska, T., Wolf, C., Kühnel, D. (2022):
Prioritising nano- and microparticles: identification of physicochemical properties relevant for toxicity to Raphidocelis subcapitata and Daphnia magna
Environ. Sci. Eur. 34 , art. 116 10.1186/s12302-022-00695-z - van Broekhuizen, P., Säämänen, A., Schuurbiers, D., Isigonis, P., Jensen, K.A., Kühnel, D., Le Blansch, K. (2022):
Tyre wear nanoparticles as test for a nano risk governance framework
Front. Environ. Sci. 10 , art. 1045246 10.3389/fenvs.2022.1045246
2021 (2)
- Arp, H.P.H., Kühnel, D., Rummel, C., MacLeod, M., Potthoff, A., Reichelt, S., Rojo-Nieto, E., Schmitt-Jansen, M., Sonnenberg, J., Toorman, E., Jahnke, A. (2021):
Weathering plastics as a planetary boundary threat: Exposure, fate, and hazards
Environ. Sci. Technol. 55 (11), 7246 - 7255 10.1021/acs.est.1c01512 - Jemec Kokalj, A., Hartmann, N.B., Drobne, D., Potthoff, A., Kühnel, D. (2021):
Quality of nanoplastics and microplastics ecotoxicity studies: Refining quality criteria for nanomaterial studies
J. Hazard. Mater. 415 , art. 125751 10.1016/j.jhazmat.2021.125751
2020 (2)
- Hund-Rinke, K., Sinram, T., Schlich, K., Nickel, C., Dickehut, H.P., Schmidt, M., Kühnel, D. (2020):
Attachment efficiency of nanomaterials to algae as an important criterion for ecotoxicity and grouping
Nanomaterials 10 (6), art. 1021 10.3390/nano10061021 - Mohaupt, V., Völker, J., Altenburger, R., Birk, S., Kirst, I., Kühnel, D., Küster, E., Semeradova, S., Šubelj, G. (2020):
Pesticides in European rivers, lakes and groundwaters – Data assessment
ETC/ICM Technical Report 1/2020
European Topic Centre on Inland, Coastal and Marine Waters, Helmholtz Centre for Environmental Research GmbH – UFZ, Magdeburg, 86 pp.
2019 (5)
- Jemec Kokalj, A., Kuehnel, D., Puntar, B., Žgajnar Gotvajn, A., Kalčikova, G. (2019):
An exploratory ecotoxicity study of primary microplastics versus aged in natural waters and wastewaters
Environ. Pollut. 254 , art. 112980 10.1016/j.envpol.2019.112980 - Kühnel, D., Nickel, C., Hellack, B., van der Zalm, E., Kussatz, C., Herrchen, M., Meisterjahn, B., Hund-Rinke, K. (2019):
Closing gaps for environmental risk screening of engineered nanomaterials
NanoImpact 15 , art. 100173 10.1016/j.impact.2019.100173 - Schmidt, S., Altenburger, R., Kühnel, D. (2019):
From the air to the water phase: implication for toxicity testing of combustion-derived particles
Biomass Convers. Biorefinery 9 (1), 213 - 225 10.1007/s13399-017-0295-1 - Weil, M., Mackenzie, K., Foit, K., Kühnel, D., Busch, W., Bundschuh, M., Schulz, R., Duis, K. (2019):
Environmental risk or benefit? Comprehensive risk assessment of groundwater treated with nano Fe0-based Carbo-Iron®
Sci. Total Environ. 677 , 156 - 166 10.1016/j.scitotenv.2019.04.360 - Wohlleben, W., Hellack, B., Nickel, C., Herrchen, M., Hund-Rinke, K., Kettler, K., Riebeling, C., Haase, A., Funk, B., Kühnel, D., Göhler, D., Stintz, M., Schumacher, C., Wiemann, M., Keller, J., Landsiedel, R., Broßell, D., Pitzko, S., Kuhlbusch, T.A.J. (2019):
The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies
Nanoscale 11 (38), 17637 - 17654 10.1039/c9nr03306h
2018 (5)
- Hund-Rinke, K., Schlich, K., Kühnel, D., Hellack, B., Kaminski, H., Nickel, C. (2018):
Grouping concept for metal and metal oxide nanomaterials with regard to their ecotoxicological effects on algae, daphnids and fish embryos
NanoImpact 9 , 52 - 60 10.1016/j.impact.2017.10.003 - Krug, H.F., Bohmer, N., Kühnel, D., Marquardt, C., Nau, K., Steinbach, C. (2018):
The DaNa2.0 Knowledge Base Nanomaterials—An important measure accompanying nanomaterials development
Nanomaterials 8 (4), art. 204 10.3390/nano8040204 - Kühnel, D. (2018):
Chapter 9. Progress towards risk assessment for engineered nanomaterials
In: Dhawan, A., Anderson, D., Shanker, R. (eds.)
Nanotoxicology: Experimental and Computational Perspectives
Issues in Toxicology 35
Royal Society of Chemistry (RSC), Cambridge, p. 232 - 247 10.1039/9781782623922-00232 - Kühnel, D., Krug, H.F., Jemec Kokalj, A. (2018):
Environmental impacts of engineered nanomaterials—imbalances in the safety assessment of selected nanomaterials
Materials 11 (8), art. 1444 10.3390/ma11081444 - Naasz, S., Altenburger, R., Kühnel, D. (2018):
Environmental mixtures of nanomaterials and chemicals: The Trojan-horse phenomenon and its relevance for ecotoxicity
Sci. Total Environ. 635 , 1170 - 1181 10.1016/j.scitotenv.2018.04.180
2017 (6)
- Böhme, S., Baccaro, M., Schmidt, M., Potthoff, A., Stärk, H.-J., Reemtsma, T., Kühnel, D. (2017):
Metal uptake and distribution in the zebrafish (Danio rerio) embryo: differences between nanoparticles and metal ions
Environ. Sci.-Nano 4 (5), 1005 - 1015 10.1039/c6en00440g - Kühnel, D., Marquardt, C., Nau, K., Krug, H.F., Paul, F., Steinbach, C. (2017):
Environmental benefits and concerns on safety: communicating latest results on nanotechnology safety research—the project DaNa2.0
Environ. Sci. Pollut. Res. 24 (12), 11120 - 11125 10.1007/s11356-016-6217-0 - Potthoff, A., Oelschlägel, K., Schmitt-Jansen, M., Rummel, C.D., Kühnel, D. (2017):
From the sea to the laboratory: Characterization of microplastic as prerequisite for the assessment of ecotoxicological impact
Integr. Environ. Assess. Manag. 13 (3), 500 - 504 10.1002/ieam.1902 - Ribeiro, A.R., Leite, P.E., Falagan-Lotsch, P., Benetti, F., Micheletti, C., Budtz, H.C., Jacobsen, N.R., Lisboa-Filho, P.N., Rocha, R.A., Kühnel, D., Hristozov, D., Granjeiro, J.M. (2017):
Challenges on the toxicological predictions of engineered nanoparticles
NanoImpact 8 , 59 - 72 10.1016/j.impact.2017.07.006 - Rummel, C.D., Jahnke, A., Gorokhova, E., Kühnel, D., Schmitt-Jansen, M. (2017):
Impacts of biofilm formation on the fate and potential effects of microplastic in the aquatic environment
Environ. Sci. Technol. Lett. 4 (7), 258 - 267 10.1021/acs.estlett.7b00164 - Steinbach, C., Bohmer, N., Krug, H.F., Kühnel, D., Nau, K., Paul, F., Reithel, S., Marquardt, C. (2017):
DaNa 2.0 – verlässliche Informationen zur Sicherheit von marktüblichen Nanomaterialien. DaNa 2.0 – reliable information on the safety of commercially available nanomaterials
Chem. Ing. Tech. 89 (3), 232 - 238 10.1002/cite.201600074
2016 (4)
- Heinlaan, M., Muna, M., Knöbel, M., Kistler, D., Odzak, N., Kühnel, D., Müller, J., Gupta, G.S., Kumar, A., Shanker, R., Sigg, L. (2016):
Natural water as the test medium for Ag and CuO nanoparticle hazard evaluation: An interlaboratory case study
Environ. Pollut. 216 , 689 - 699 10.1016/j.envpol.2016.06.033 - Jemec, A., Kahru, A., Potthoff, A., Drobne, D., Heinlaan, M., Böhme, S., Geppert, M., Novak, S., Schirmer, K., Rekulapally, R., Singh, S., Aruoja, V., Sihtmäe, M., Juganson, K., Käkinen, A., Kühnel, D. (2016):
An interlaboratory comparison of nanosilver characterisation and hazard identification: Harmonising techniques for high quality data
Environ. Int. 87 , 20 - 32 10.1016/j.envint.2015.10.014 - Kos, M., Kahru, A., Drobne, D., Singh, S., Kalčíková, G., Kühnel, D., Rohit, R., Žgajnar Gotvajn, A., Jemec, A. (2016):
A case study to optimise and validate the brine shrimp Artemia franciscana immobilisation assay with silver nanoparticles: The role of harmonisation
Environ. Pollut. 213 , 173 - 183 10.1016/j.envpol.2016.02.015 - Nau, K., Bohmer, N., Kühnel, D., Marquardt, C., Paul, F., Steinbach, C., Krug, H.F. (2016):
The DaNa2.0 knowledge base on nanomaterials – Communicating current nanosafety research based on evaluated literature data
J. Mat. Educ. 38 (3-4), 93 - 108
2015 (5)
- Böhme, S., Kühnel, D., Stärk, H.-J., Reemtsma, T. (2015):
New developments in the field of the visualization of nanoparticle uptake by environmental organisms with LA-ICP-MS
In: Daus, B., Bings, N., Leopold, K., Otto, M., Panne, U., Welz, U., Wennrich, R. (eds.)
Canas ’15. Colloquium Analytische Atomspektroskopie, 8.–11. März 2015, Helmholtz-Zentrum für Umweltforschung – UFZ Leipzig. Colloquium Analytical Atomic Spectroscopy, 8–11 March, 2015, Helmholtz Centre for Environmental Research – UFZ Leipzig
Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, 61 - 62 - Böhme, S., Stärk, H.-J., Kühnel, D., Reemtsma, T. (2015):
Exploring LA-ICP-MS as a quantitative imaging technique to study nanoparticle uptake in Daphnia magna and zebrafish (Danio rerio) embryos
Anal. Bioanal. Chem. 407 (18), 5477 - 5485 10.1007/s00216-015-8720-4 - Böhme, S., Stärk, H.-J., Reemtsma, T., Kühnel, D. (2015):
Effect propagation after silver nanoparticle exposure in zebrafish (Danio rerio) embryos: a correlation to internal concentration and distribution patterns
Environ. Sci.-Nano 2 (6), 603 - 614 10.1039/c5en00118h - Potthoff, A., Weil, M., Meißner, T., Kühnel, D. (2015):
Towards sensible toxicity testing for nanomaterials: proposal for the specification of test design
Sci. Technol. Adv. Mater. 16 (6), art. 065006 10.1088/1468-6996/16/6/065006 - Weil, M., Meißner, T., Busch, W., Springer, A., Kühnel, D., Schulz, R., Duis, K. (2015):
The oxidized state of the nanocomposite Carbo-Iron® causes no adverse effects on growth, survival and differential gene expression in zebrafish
Sci. Total Environ. 530-531 , 198 - 208 10.1016/j.scitotenv.2015.05.087
2014 (6)
- Böhme, S., Stärk, H.-J., Meißner, T., Springer, A., Reemtsma, T., Kühnel, D., Busch, W. (2014):
Quantification of Al2O3 nanoparticles in human cell lines applying inductively coupled plasma mass spectrometry (neb-ICP-MS, LA-ICP-MS) and flow cytometry-based methods
J. Nanopart. Res. 16 , 2592 10.1007/s11051-014-2592-y - Krug, H.F., Wick, P., Hirsch, C., Kühnel, D., Marquardt, C., Nau, K., Mathes, B., Steinbach, C. (2014):
Im Gleichgewicht? Risikoforschung zu Nanomaterialien : die internationale Risikodebatte zur Nanotechnologie und zu möglichen Vorsorgemaßnahmen für Arbeitsplatz und Verbraucher
Arbeitsmedizin, Sozialmedizin, Umweltmedizin : ASU 43 (1), 6 - 18 - Kühnel, D., Marquardt, C., Nau, K., Krug, H.F., Mathes, B., Steinbach, C. (2014):
Environmental impacts of nanomaterials: providing comprehensive information on exposure, transport and ecotoxicity - the project DaNa2.0
Environ. Sci. Eur. 26 , art. 21 10.1186/s12302-014-0021-6 - Kühnel, D., Nickel, C. (eds., 2014):
Ecotoxicology and environmental fate of manufactured nanomaterials: test guidelines
Series on the Safety of Manufactured Nanomaterials 40 - ENV/JM/MONO(2014)1
OECD Organisation for Economic Co-operation and Development, Paris, 84 pp. - Kühnel, D., Nickel, C. (2014):
The OECD expert meeting on ecotoxicology and environmental fate — towards the development of improved OECD guidelines for the testing of nanomaterials
Sci. Total Environ. 472 , 347 - 353 10.1016/j.scitotenv.2013.11.055 - Oomen, A.G., Bos, P.M.J., Fernandes, T.F., Hund-Rinke, K., Boraschi, D., Byrne, H.J., Aschberger, K., Gottardo, S., von der Kammer, F., Kühnel, D., Hristozov, D., Marcomini, A., Migliore, L., Scott-Fordsmand, J., Wick, P., Landsiedel, R. (2014):
Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10
Nanotoxicology 8 (3), 334 - 348 10.3109/17435390.2013.802387
2013 (3)
- Jackson, P., Jacobsen, N.R., Baun, A., Birkedal, R., Kühnel, D., Jensen, K.A., Vogel, U., Wallin, H. (2013):
Bioaccumulation and ecotoxicity of carbon nanotubes
Chem. Cent. J. 7 , 154 10.1186/1752-153X-7-154 - Kroll, A., Kühnel, D., Schirmer, K. (2013):
Testing nanomaterial toxicity in unicellular eukaryotic algae and fish cell lines
In: Armstrong, D., Bharali, D.J. (eds.)
Oxidative stress and nanotechnology: methods and protocols
Methods in Molecular Biology 1028
Springer Nature, p. 165 - 195 10.1007/978-1-62703-475-3_11 - Marquardt, C., Kühnel, D., Richter, V., Krug, H.F., Mathes, B., Steinbach, C., Nau, K. (2013):
Latest research results on the effects of nanomaterials on humans and the environment: DaNa - Knowledge Base Nanomaterials
J. Phys.: Conf. Ser. 429 , 012060 10.1088/1742-6596/429/1/012060
2012 (2)
- Kühnel, D., Scheffler, K., Wellner, P., Meißner, T., Potthoff, A., Busch, W., Springer, A., Schirmer, K. (2012):
Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro
J. Hazard. Mater. 227-228 , 418 - 426 10.1016/j.jhazmat.2012.04.070 - Steinbach, C., Mathes, B., Krug, H.F., Wiek, P., Kühnel, D. (2012):
Die Sicherheit von Nanomaterialien in der Diskussion
Deutsche Apotheker-Zeitung 152 (16), 90 - 92
2011 (1)
- Busch, W., Bastian, S., Trahorsch, U., Iwe, M., Kühnel, D., Meißner, T., Springer, A., Gelinsky, M., Richter, V., Ikonomidou, C., Potthoff, A., Lehmann, I., Schirmer, K. (2011):
Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties
J. Nanopart. Res. 13 (1), 293 - 310 10.1007/s11051-010-0030-3
2010 (5)
- Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y. (2010):
Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
UWSF - Z. Umweltchem. Ökotox. 22 (4), 502 - 506 10.1007/s12302-010-0142-5 - Busch, W., Kühnel, D., Schirmer, K., Scholz, S. (2010):
Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes
BMC Genomics 11 , art. 65 10.1186/1471-2164-11-65 - Hildebrand, H., Kühnel, D., Potthoff, A., Mackenzie, K., Springer, A., Schirmer, K. (2010):
Evaluating the cytotoxicity of palladium/magnetite nano-catalysts intended for wastewater treatment
Environ. Pollut. 158 (1), 65 - 73 10.1016/j.envpol.2009.08.021 - Meissner, T., Kühnel, D., Busch, W., Oswald, S., Richter, V., Michaelis, A., Schirmer, K., Potthoff, A. (2010):
Physical-chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations
Nanotoxicology 4 (2), 196 - 206 10.3109/17435391003605455 - Stärk, H.-J., Kühnel, D., Busch, W., Wellner, P., Schirmer, C. (2010):
Charakterisierung der Aufnahme von Wolframkarbid-Nanopartikeln durch Humanzellen mittels LA-ICP-MS
In: Otto, M., Bulska, E., Knapp, G., Schlemmer, G., Ullrich, A., Welz, B., Wennrich, R. (Hrsg.)
CANAS '09 - Colloquium Analytische Atomspektroskopie, 22.-25. März 2009, Freiberg
TU Bergakademie Freiberg, Institut für Analytische Chemie, Freiberg, 44 - 44
2009 (5)
- Bastian, S., Busch, W., Kühnel, D., Springer, A., Meißner, T., Holke, R., Scholz, S., Iwe, M., Pompe, W., Gelinsky, M., Potthoff, A., Richter, V., Ikonomidou, H., Schirmer, K. (2009):
Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro
Environ. Health Perspect. 117 (4), 530 - 536 10.1289/ehp.0800121 - Busch, W., Kühnel, D., Springer, A., Meissner, T., Gelinsky, M., Potthoff, A., Scholz, S., Richter, V., Schirmer, K. (2009):
Tungsten carbide and tungsten carbide cobalt nanoparticle toxicity: The role of cellular particle uptake, leached ions and cobalt bioavailability
Toxicol. Lett. 189 (Suppl. 1), S185 - S185 10.1016/j.toxlet.2009.06.645 - Kühnel, D., Busch, W., Meissner, T., Springer, A., Potthoff, A., Richter, V., Gelinsky, M., Scholz, S., Schirmer, K. (2009):
Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line
Aquat. Toxicol. 93 (2-3), 91 - 99 10.1016/j.aquatox.2009.04.003 - Kühnel, D., Taugner, F., Scholtka, B., Steinberg, P. (2009):
Inflammation does not precede or accompany the induction of preneoplastic lesions in the colon of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-fed rats
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