Dr. Till Luckenbach
Helmholtz-Zentrum für
Umweltforschung - UFZ
Permoserstr. 15
04318 Leipzig
Gebäude: 6.0
Raum: 229
Telefon: +49 341 6025 1514
Forschungsinteressen
- Aquatische molekulare Ökotoxikologie
molekulare Mechanismen, die die Aufnahme von Chemikalien von außen steuern
- Wechselwirkungen von Umweltschadstoffen mit diesem System
Lebenslauf
Seit 2009
Senior Researcher und Gruppenleiter, Department Bioanalytische Ökotoxikologie, Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, Deutschland
2006 - 2009
PotDoc, Department Zelltoxikologie und Bioanalytische Ökotoxikologie, Helmholtz-Zentrum für Umweltforschung - UFZ, Leipzig, Germany
2002 - 2005
PostDoc, Stanford University, USA
2002
PostDoc, Max-Planck Institute for Developmental Biology, Tübingen, Germany
1998 - 2002
Ph.D. Zoologie, Universität Tübingen, Deutschland
Titel der Dissertation: Feld- und Laborstudien über die Auswirkungen von Umweltverschmutzung auf die Entwicklung der Bachforelle.
1991 - 1998
Diplom in Biologie, Universität Tübingen, Deutschland
Titel der Diplomarbeit: Ein Semi-Feld-Ansatz zur Untersuchung der Auswirkungen von Flussverschmutzung auf dieEntwicklung von Fischen.
Auszeichnungen
2018
German PI in the German-Russian “Helmholtz – RSF Joint Research Group” “LaBeglo II” (390,000 € for three years)
2016
funding for a PhD position
2015
funding for a PhD position
2011
Leading applicant for UFZ internal funds
2010
German PI in the German-Russian “Helmholtz-Russia Young Investigator Group” “LaBeglo” (390,000 € for three years)
2009
Grant awarded by the DAAD and the Spanish government
2007
Grant awarded by the DAAD and the Croatian Ministry
2007
Early career grant awarded by the DFG (105,000 €)
2006
Best Publication Award
10/2006
GDCh (Gesellschaft deutscher Chemiker); Environmental Toxicology Meeting; Halle (Saale), Germany
2006
DFG fellowship for German scientists abroad who return to Germany
11/2005
Best Poster Award, SCORE (Student Collaborations for Ocean Research and Education at Stanford University) meeting; Pacific Grove, CA
06/2005
Best Poster Award, PRIMO 13 (Pollution responses in marine organisms); Alessandria, Italy
05/2005
Best Poster Award, SETAC Norcal meeting; Berkeley, CA
2005
Postdoctoral fellowship awarded by the DFG to conduct research at Stanford University, USA
2004
CoAuthor on approved grant proposal to the NSF (National Science Foundation)
2002 - 2004
Postdoctoral fellowship awarded by the DAAD to conduct research at Stanford University, USA
2000 - 2002
PhD fellowship awarded by the state of Baden-Württemberg, Germany
2000
Grant awarded by the foundation for the environment from the Landesbank Baden-Württemberg
(26,000 DM; equivalent to 13,000 €)
1999
PhD fellowship awarded by the DAAD to conduct research at Stanford University, USA
Publikationen
2024 (2)
- Luckenbach, T., Burkhardt-Medicke, K. (2024):
Differing temperature dependencies of functional homologs zebrafish Abcb4 and human ABCB1
Front. Pharmacol. 15 , art. 1426040 10.3389/fphar.2024.1426040 - Romano, P., Simonetti, S., Gambi, M.C., Luckenbach, T., Zupo, V., Corsi, I. (2024):
Preliminary investigation on the potential involvement of an ABC-like gene in Halomicronema metazoicum (Cyanobacteria) tolerance to low seawater pH in an ocean acidification scenario
Mar. Pollut. Bull. 205 , art. 116584 10.1016/j.marpolbul.2024.116584
2023 (2)
- Lipaeva, P., Karkossa, I., Bedulina, D., Schubert, K., Luckenbach, T. (2023):
Cold-adapted amphipod species upon heat stress: Proteomic responses and their correlation with transcriptomic responses
Comp. Biochem. Physiol. D-Genomics Proteomics 45 , art. 101048 10.1016/j.cbd.2022.101048 - Lubyaga, Y., Yarinich, L., Drozdova, P., Pindyurin, A., Gurkov, A., Luckenbach, T., Timofeyev, M. (2023):
The ABCs of the amphipod P-glycoprotein: Heterologous production of the Abcb1 protein of a model species Eulimnogammarus verrucosus (Amphipoda: Gammaridae) from Lake Baikal
Comp. Biochem. Physiol. C-Toxicol. Pharmacol. 271 , art. 109677 10.1016/j.cbpc.2023.109677
2022 (5)
- Halbach, K., Aulhorn, S., Lechtenfeld, O.J., Lecluse, M., Leippe, S., Reemtsma, T., Seiwert, B., Wagner, S., König, J., Luckenbach, T. (2022):
Zebrafish Oatp1d1 acts as a cellular efflux transporter of the anionic herbicide bromoxynil
Chem. Res. Toxicol. 35 (2), 315 - 325 10.1021/acs.chemrestox.1c00371 - Ortmann, J., Altenburger, R., Scholz, S., Luckenbach, T. (2022):
Photomotor response data analysis approach to assess chemical neurotoxicity with the zebrafish embryo
ALTEX-Altern. Anim. Exp. 39 (1), 82 - 94 10.14573/altex.2004021 - Simonetti, S., Zupo, V., Gambi, M.C., Luckenbach, T., Corsi, I. (2022):
Unraveling cellular and molecular mechanisms of acid stress tolerance and resistance in marine species: New frontiers in the study of adaptation to ocean acidification
Mar. Pollut. Bull. 185, Part B , art. 114365 10.1016/j.marpolbul.2022.114365 - Švara, V., Michalski, S.G., Krauss, M., Schulze, T., Geuchen, S., Brack, W., Luckenbach, T. (2022):
Reduced genetic diversity of freshwater amphipods in rivers with increased levels of anthropogenic organic micropollutants
Evol. Appl. 15 (6), 976 - 991 10.1111/eva.13387 - Švara, V., Michalski, S.G., Krauss, M., Schulze, T., Geuchen, S., Brack, W., Luckenbach, T. (2022):
Reduced genetic diversity of freshwater amphipods in rivers with increased levels of anthropogenic organic micropollutants [Dataset]
Dryad 10.5061/dryad.zw3r2288p
2021 (6)
- Bedulina, D., Drozdova, P., Gurkov, A., von Bergen, M., Stadler, P.F., Luckenbach, T., Timofeyev, M., Kalkhof, S. (2021):
Proteomics reveals sex-specific heat shock response of Baikal amphipod Eulimnogammarus cyaneus
Sci. Total Environ. 763 , art. 143008 10.1016/j.scitotenv.2020.143008 - Bieczynski, F., Burkhardt-Medicke, K., Luquet, C.M., Scholz, S., Luckenbach, T. (2021):
Chemical effects on dye efflux activity in live zebrafish embryos and on zebrafish Abcb4 ATPase activity
FEBS Lett. 595 (6), 828 - 843 10.1002/1873-3468.14015 - Jakob, L., Vereshchagina, K.P., Tillmann, A., Rivarola-Duarte, L., Axenov-Gribanov, D.V., Bedulina, D.S., Gurkov, A.N., Drozdova, P., Timofeyev, M.A., Stadler, P.F., Luckenbach, T., Pörtner, H.-O., Sartoris, F.J., Lucassen, M. (2021):
Thermal reaction norms of key metabolic enzymes reflect divergent physiological and behavioral adaptations of closely related amphipod species
Sci. Rep. 11 , art. 4562 10.1038/s41598-021-83748-2 - Lipaeva, P., Vereshchagina, K., Drozdova, P., Jakob, L., Kondrateva, E., Lucassen, M., Bedulina, D., Timofeyev, M., Stadler, P., Luckenbach, T. (2021):
Different ways to play it cool: Transcriptomic analysis sheds light on different activity patterns of three amphipod species under long-term cold exposure
Mol. Ecol. 30 (22), 5735 - 5751 10.1111/mec.16164 - Švara, V., Krauss, M., Michalski, S.G., Altenburger, R., Brack, W., Luckenbach, T. (2021):
Chemical pollution levels in a river explain site-specific sensitivities to micropollutants within a genetically homogeneous population of freshwater amphipods
Environ. Sci. Technol. 55 (9), 6087 - 6096 10.1021/acs.est.0c07839 - Vereshchagina, K., Kondrateva, E., Mutin, A., Jakob, L., Bedulina, D., Shchapova, E., Madyarova, E., Axenov-Gribanov, D., Luckenbach, T., Pörtner, H.-O., Lucassen, M., Timofeyev, M. (2021):
Low annual temperature likely prevents the Holarctic amphipod Gammarus lacustris from invading Lake Baikal
Sci. Rep. 11 , art. 10532 10.1038/s41598-021-89581-x
2020 (3)
- Halbach, K., Ulrich, N., Goss, K.-U., Seiwert, B., Wagner, S., Scholz, S., Luckenbach, T., Bauer, C., Schweiger, N., Reemtsma, T. (2020):
Yolk sac of zebrafish embryos as backpack for chemicals?
Environ. Sci. Technol. 54 (16), 10159 - 10169 10.1021/acs.est.0c02068 - Protopopova, M.V., Pavlichenko, V.V., Luckenbach, T. (2020):
Changes of cellular stress response related hsp70 and abcb1 transcript and Hsp70 protein levels in Siberian freshwater amphipods upon exposure to cadmium chloride in the lethal concentration range
PeerJ 8 , e8635 10.7717/peerj.8635 - Shatilina, Z., Drozdova, P., Bedulina, D., Rivarola-Duarte, L., Schreiber, S., Otto, C., Jühling, F., Aulhorn, S., Busch, W., Lubyaga, Y., Kondrateva, E., Pobezhimova, T., Jakob, L., Lucassen, M., Sartoris, F.J., Hackermüller, J., Pörtner, H.-O., Stadler, P.F., Luckenbach, T., Timofeyev, M. (2020):
Transcriptome-level effects of the model organic pollutant phenanthrene and its solvent acetone in three amphipod species
Comp. Biochem. Physiol. D-Genomics Proteomics 33 , art. 100630 10.1016/j.cbd.2019.100630
2019 (5)
- Drozdova, P., Bedulina, D., Madyarova, E., Rivarola-Duarte, L., Schreiber, S., Stadler, P.F., Luckenbach, T., Timofeyev, M. (2019):
Description of strongly heat-inducible heat shock protein 70 transcripts from Baikal endemic amphipods
Sci. Rep. 9 , art. 8907 10.1038/s41598-019-45193-0 - Drozdova, P., Rivarola-Duarte, L., Bedulina, D., Axenov-Gribanov, D., Schreiber, S., Gurkov, A., Shatilina, Z., Vereshchagina, K., Lubyaga, Y., Madyarova, E., Otto, C., Jühling, F., Busch, W., Jakob, L., Lucassen, M., Sartoris, F.J., Hackermüller, J., Hoffmann, S., Pörtner, H.-O., Luckenbach, T., Timofeyev, M., Stadler, P.F. (2019):
Comparison between transcriptomic responses to short-term stress exposures of a common Holarctic and endemic Lake Baikal amphipods
BMC Genomics 20 , art. 712 10.1186/s12864-019-6024-3 - Gurkov, A., Rivarola-Duarte, L., Bedulina, D., Fernández Casas, I., Michael, H., Drozdova, P., Nazarova, A., Govorukhina, E.B., Timofeyev, M., Stadler, P.F., Luckenbach, T. (2019):
Indication of ongoing amphipod speciation in Lake Baikal by genetic structures within endemic species
BMC Evol. Biol. 19 , art. 138 10.1186/s12862-019-1470-8 - Halbach, K., Wagner, S., Scholz, S., Luckenbach, T., Reemtsma, T. (2019):
Elemental imaging (LA-ICP-MS) of zebrafish embryos to study the toxicokinetics of the acetylcholinesterase inhibitor naled
Anal. Bioanal. Chem. 411 (3), 617 - 627 10.1007/s00216-018-1471-2 - Švara, V., Norf, H., Luckenbach, T., Brack, W., Michalski, S.G. (2019):
Isolation and characterization of eleven novel microsatellite markers for fine-scale population genetic analyses of Gammarus pulex (Crustacea: Amphipoda)
Mol. Biol. Rep. 46 (6), 6609 - 6615 10.1007/s11033-019-05077-y
2018 (2)
- Oetken, M., Jungmann, D., Bundschuh, M., Heß, M., Höss, S., Klein, R., Luckenbach, T., Osterauer, R., Peschke, K., Sosat, R. (2018):
Aquatische Wirbellose – inwiefern können sie als Wirkungsindikatoren für eine Gewässerbelastung dienen? Aquatic invertebrates - How can they serve as output indicators of water pollution?
Gefahrst. Reinhalt. Luft 78 (4), 171 - 172 - Piotrowska, A., Syguda, A., Wyrwas, B., Chrzanowski, Ł., Luckenbach, T., Heipieper, H.J. (2018):
Effects of ammonium-based ionic liquids and 2,4-dichlorophenol on the phospholipid fatty acid composition of zebrafish embryos
PLOS One 13 (1), e0190779 10.1371/journal.pone.0190779
2017 (6)
- Armitage, J.M., Erickson, R.J., Luckenbach, T., Ng, C.A., Prosser, R.S., Arnot, J.A., Schirmer, K., Nichols, J.W. (2017):
Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities
Environ. Toxicol. Chem. 36 (4), 882 - 897 10.1002/etc.3680 - Cunha, V., Burkhardt-Medicke, K., Wellner, P., Santos, M.M., Moradas-Ferreira, P., Luckenbach, T., Ferreira, M. (2017):
Effects of pharmaceuticals and personal care products (PPCPs) on multixenobiotic resistance (MXR) related efflux transporter activity in zebrafish (Danio rerio) embryos
Ecotox. Environ. Safe. 136 , 14 - 23 10.1016/j.ecoenv.2016.10.022 - Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F. (2017):
From the exposome to mechanistic understanding of chemical-induced adverse effects
Environ. Int. 99 , 97 - 106 10.1016/j.envint.2016.11.029 - Jakob, L., Bedulina, D.S., Axenov-Gribanov, D.V., Ginzburg, M., Shatilina, Z.M., Lubyaga, Y.A., Madyarova, E.V., Gurkov, A.N., Timofeyev, M.A., Portner, H.-O., Sartoris, F.J., Altenburger, R., Luckenbach, T. (2017):
Uptake kinetics and subcellular compartmentalization explain lethal but not sublethal effects of cadmium in two closely related amphipod species
Environ. Sci. Technol. 51 (12), 7208 - 7218 10.1021/acs.est.6b06613 - Kurth, D., Lips, S., Massei, R., Krauss, M., Luckenbach, T., Schulze, T., Brack, W. (2017):
The impact of chemosensitisation on bioaccumulation and sediment toxicity
Chemosphere 186 , 652 - 659 10.1016/j.chemosphere.2017.08.019 - Luckenbach, T. (2017):
What are the global boundaries of chemical pollution? Каковы глобальные границы химического загрязнения?
Russian-German Scientific Summer School „Scientific collaboration – contribution to sustainable development“, October 16-22, 2016, Sochi. The Noosphere [Noosfera] No 1/2017
V.I. Vernadsky Nongovernmental Ecological Foundation ; Helmholtz Association of the German Scientific Centers, Moskau, Berlin, p. 59 - 63
2016 (5)
- Axenov-Gribanov, D., Bedulina, D., Shatilina, Z., Jakob, L., Vereshchagina, K., Lubyaga, Y., Gurkov, A., Shchapova, E., Luckenbach, T., Lucassen, M., Sartoris, F.J., Pörtner, H.-O., Timofeyev, M. (2016):
Thermal preference ranges correlate with stable signals of universal stress markers in Lake Baikal endemic and Holarctic amphipods
PLOS One 11 (10), e0164226 10.1371/journal.pone.0164226 - Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T. (2016):
Corrigendum to "Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue" [Toxicol. Appl. Pharmacol. (2016) 56–67]
Toxicol. Appl. Pharmacol. 303 , 110 10.1016/j.taap.2016.04.015 - Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T. (2016):
Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue
Toxicol. Appl. Pharmacol. 297 , 56 - 67 10.1016/j.taap.2016.02.020 - Jakob, L., Axenov-Gribanov, D.V., Gurkov, A.N., Ginzburg, M., Bedulina, D.S., Timofeyev, M.A., Luckenbach, T., Lucassen, M., Sartoris, F.J., Pörtner, H.-O. (2016):
Lake Baikal amphipods under climate change: thermal constraints and ecological consequences
Ecosphere 7 (3), e01308 10.1002/ecs2.1308 - Keiter, S., Burkhardt-Medicke, K., Wellner, P., Kais, B., Färber, H., Skutlarek, D., Engwall, M., Braunbeck, T., Keiter, S.H., Luckenbach, T. (2016):
Does perfluorooctane sulfonate (PFOS) act as chemosensitizer in zebrafish embryos?
Sci. Total Environ. 548–549 , 317 - 324 10.1016/j.scitotenv.2015.12.089
2015 (5)
- Hachicho, N., Reithel, S., Miltner, A., Heipieper, H.J., Küster, E., Luckenbach, T. (2015):
Body mass parameters, lipid profiles and protein contents of zebrafish embryos and effects of 2,4-dinitrophenol exposure
PLOS One 10 (8), e0134755 10.1371/journal.pone.0134755 - Kurth, D., Brack, W., Luckenbach, T. (2015):
Is chemosensitisation by environmental pollutants ecotoxicologically relevant?
Aquat. Toxicol. 167 , 134 - 140 10.1016/j.aquatox.2015.07.017 - Luckenbach, T., Bedulina, D.S., Timofeyev, M. (2015):
Is the endemic fauna of Lake Baikal affected by global change?
In: Karthe, D., Chalov, S.R., Kasimov, N.S., Kappas, M. (eds.)
Water and environment in the Selenga-Baikal Basin. International research cooperation for an ecoregion of global relevance
Earth View - Geography and Geoinformation 23
Ibidem-Verlag, Stuttgart, p. 219 - 235 - Luckenbach, T., Küster, E., Busch, W., Scholz, S., Altenburger, R. (2015):
What determines chemical uptake by the zebrafish embryo model?
Toxicol. Lett. 238 (2, Suppl.), S54 10.1016/j.toxlet.2015.08.151 - Pavlichenko, V.V., Protopopova, M.V., Timofeyev, M., Luckenbach, T. (2015):
Identification of a putatively multixenobiotic resistance related Abcb1 transporter in amphipod species endemic to the highly pristine Lake Baikal
Environ. Sci. Pollut. Res. 22 (7), 5453 - 5468 10.1007/s11356-014-3758-y
2014 (5)
- Bedulina, D.S., Takhteev, V.V., Pogrebnyak, S.G., Govorukhina, E.B., Madyarova, E.V., Lubyaga, Y.A., Vereshchagina, K.P., Timofeyev, M.A., Luckenbach, T. (2014):
On Eulimnogammarus messerschmidtii, sp. n. (Amphipoda: Gammaridea) from Lake Baikal, Siberia, with redescription of E. cyanoides (Sowinsky) and remarks on taxonomy of the genus Eulimnogammarus
Zootaxa 3838 (5), 518 - 544 10.11646/zootaxa.3838.5.2 - Campos, B., Altenburger, R., Gómez, C., Lacorte, S., Piña, B., Barata, C., Luckenbach, T. (2014):
First evidence for toxic defense based on the multixenobiotic resistance (MXR) mechanism in Daphnia magna
Aquat. Toxicol. 148 , 139 - 151 10.1016/j.aquatox.2014.01.001 - Luckenbach, T., Fischer, S., Sturm, A. (2014):
Current advances on ABC drug transporters in fish
Comp. Biochem. Physiol. C-Toxicol. Pharmacol. 165 , 28 - 52 10.1016/j.cbpc.2014.05.002 - Protopopova, M.V., Pavlichenko, V.V., Menzel, R., Putschew, A., Luckenbach, T., Steinberg, C.E.W. (2014):
Contrasting cellular stress responses of Baikalian and Palearctic amphipods upon exposure to humic substances: environmental implications
Environ. Sci. Pollut. Res. 21 (24), 14124 - 14137 10.1007/s11356-014-3323-8 - Rivarola-Duarte, L., Otto, C., Jühling, F., Schreiber, S., Bedulina, D.S., Jakob, L., Gurkov, A., Axenov-Gribanov, D., Sahyoun, A.H., Lucassen, M., Hackermüller, J., Hoffmann, S., Sartoris, F., Pörtner, H.-O., Timofeyev, M., Luckenbach, T., Stadler, P.F. (2014):
A first glimpse at the genome of the Baikalian amphipod Eulimnogammarus verrucosus
J. Exp. Zool. Part B 322 (3), 177 - 189 10.1002/jez.b.22560
2013 (4)
- Bedulina, D.S., Evgen'ev, M.B., Timofeyev, M.A., Protopopova, M.V., Garbuz, D.G., Pavlichenko, V.V., Luckenbach, T., Shatilina, Z.M., Axenov-Gribanov, D.V., Gurkov, A.N., Sokolova, I.M., Zatsepina, O.G. (2013):
Expression patterns and organization of the hsp70 genes correlate with thermotolerance in two congener endemic amphipod species (Eulimnogammarus cyaneus and E. verrucosus) from Lake Baikal
Mol. Ecol. 22 (5), 1416 - 1430 10.1111/mec.12136 - Fischer, S., Klüver, N., Burkhardt-Medicke, K., Pietsch, M., Schmidt, A.-M., Wellner, P., Schirmer, K., Luckenbach, T. (2013):
Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos
BMC Biol. 11 , art. 69 10.1186/1741-7007-11-69 - Madyarova, E.V., Lubyaga, J.A., Gurkov, A.N., Vereshchagina, K.P., Kondrateva, E.M., Shchapova, E.P., Timofeyev, M.A., Luckenbach, T., Bedulina, D.S. (2013):
A comparative analysis of hsp70 mRNA and HSP70 protein expression in two distant populations of the Baikal amphipod Eulimnogammarus verrucosus (Gerstf., 1858)
Journal of Stress Physiology & Biochemistry 9 (4), 345 - 351 - Scholz, S., Sela, E., Blaha, L., Braunbeck, T., Galay-Burgos, M., García-Franco, M., Guinea, J., Klüver, N., Schirmer, K., Tanneberger, K., Tobor-Kapłon, M., Witters, H., Belanger, S., Benfenati, E., Creton, S., Cronin, M.T.D., Eggen, R.I.L., Embry, M., Ekman, D., Gourmelon, A., Halder, M., Hardy, B., Hartung, T., Hubesch, B., Jungmann, D., Lampi, M.A., Lee, L., Léonard, M., Küster, E., Lillicrap, A., Luckenbach, T., Murk, A.J., Navas, J.M., Peijnenburg, W., Repetto, G., Salinas, E., Schüürmann, G., Spielmann, H., Tollefsen, K.E., Walter-Rohde, S., Whale, G., Wheeler, J.R., Winter, M.J. (2013):
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment
Regul. Toxicol. Pharmacol. 67 (3), 506 - 530 10.1016/j.yrtph.2013.10.003
2012 (1)
- Navarro, A., Weißbach, S., Faria, M., Barata, C., Piña, B., Luckenbach, T. (2012):
Abcb and Abcc transporter homologs are expressed and active in larvae and adults of zebra mussel and induced by chemical stress
Aquat. Toxicol. 122–123 , 144 - 152 10.1016/j.aquatox.2012.06.008
2011 (2)
- Faria, M., Navarro, A., Luckenbach, T., Piña, B., Barata, C. (2011):
Characterization of the multixenobiotic resistance (MXR) mechanism in embryos and larvae of the zebra mussel (Dreissena polymorpha) and studies on its role in tolerance to single and mixture combinations of toxicants
Aquat. Toxicol. 101 (1), 78 - 87 10.1016/j.aquatox.2010.09.004 - Fischer, S., Loncar, J., Zaja, R., Schnell, S., Schirmer, K., Smital, T., Luckenbach, T. (2011):
Constitutive mRNA expression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss)
Aquat. Toxicol. 101 (2), 438 - 446 10.1016/j.aquatox.2010.11.010
2010 (3)
- Brennan, C., Dosch, R., Haramis, A.-P., Luckenbach, T., Martínez-Morales, J.-R., Moro, E., Polok, B., Ramesch, T.M., Russell, C., Argenton, F., Strähle, U. (2010):
Report of the European Zebrafish Principal Investigator Meeting in Padua, Italy, March 18-22, 2010
Zebrafish 7 (3), 305 - 310 10.1089/zeb.2010.0668 - Fischer, S., Pietsch, M., Schirmer, K., Luckenbach, T. (2010):
Identification of multi-drug resistance associated proteins MRP1 (ABCC1) and MRP3 (ABCC3) from rainbow trout (Oncorhynchus mykiss)
Mar. Environ. Res. 69 (Suppl. 1), S7 - S10 10.1016/j.marenvres.2009.11.003 - Zucchi, S., Corsi, I., Luckenbach, T., Bard, S.M., Regoli, F., Focardi, S. (2010):
Identification of five partial ABC genes in the liver of the Antarctic fish Trematomus bernacchii and sensitivity of ABCB1 and ABCC2 to Cd exposure
Environ. Pollut. 158 (8), 2746 - 2756 10.1016/j.envpol.2010.04.012
2008 (5)
- Epel, D., Luckenbach, T., Stevenson, C.N., MacManus-Spencer, L.A., Hamdoun, A., Smital, T. (2008):
Efflux transporters: newly appreciated roles in protection against pollutants
Environ. Sci. Technol. 42 (11), 3914 - 3920 10.1021/es087187v - Luckenbach, T., Ahnert, M., Fischer, S., Schirmer, K. (2008):
Zebrafish embryos are sensitized towards chemicals by efflux transporter inhibitors
Mar. Environ. Res. 66 (1), 81 10.1016/j.marenvres.2008.02.029 - Luckenbach, T., Altenburger, R., Epel, D. (2008):
Teasing apart activities of different types of ABC efflux pumps in bivalve gills using the concepts of independent action and concentration addition
Mar. Environ. Res. 66 (1), 75 - 76 10.1016/j.marenvres.2008.02.027 - Luckenbach, T., Epel, D. (2008):
ABCB- and ABCC-type transporters confer multixenobiotic resistance and form an environment-tissue barrier in bivalve gills
Am. J. Physiol.-Regul. Integr. Comp. Physiol. 294 , R1919 - R1929 10.1152/ajpregu.00563.2007 - Scholz, S., Fischer, S., Gündel, U., Küster, E., Luckenbach, T., Voelker, D. (2008):
The zebrafish embryo model in environmental risk assessment - applications beyond acute toxicity testing
Environ. Sci. Pollut. Res. 15 (5), 394 - 404 10.1007/s11356-008-0018-z
2006 (3)
- Luckenbach, T., Epel, D. (2006):
The chemosensitizer problem: Unraveling how musks inhibit efflux transporters in mussels and use of this approach for predicting chemo sensitizing potential
Mar. Environ. Res. 62 (Suppl. 1), S69 - S70 10.1016/j.marenvres.2006.04.037 - Smital, T., Sauerborn, R., Zaja, R., Luckenbach, T., Hamdoun, A.M., Epel, D. (2006):
Multidrug resistance-associated proteins (MRPs) as an integral part of multixenobiotic resistance (MXR) in aquatic organisms
Mar. Environ. Res. 62 (Suppl. 1), S46 - S47 10.1016/j.marenvres.2006.04.037 - Stevenson, C.N., MacManus-Spencer, L.A., Luckenbach, T., Luthy, R.G., Epel, D. (2006):
New perspectives on perfluorochemical ecotoxicology: inhibition and induction of an efflux transporter in the marine mussel, Mytilus californianus
Environ. Sci. Technol. 40 (17), 5580 - 5585 10.1021/es0602593
2005 (2)
- Hallare, A.V., Schirling, M., Luckenbach, T., Köhler, H.-R., Triebskorn, R. (2005):
Combined effects of temperature and cadmium on developmental parameters and biomarker responses in zebrafish (Danio rerio) embryos
J. Therm. Biol. 30 (1), 7 - 17 10.1016/j.jtherbio.2004.06.002 - Luckenbach, T., Epel, D. (2005):
Nitromusk and polycyclic musk compounds as long-term inhibitors of cellular xenobiotic defense systems mediated by multidrug transporters
Environ. Health Perspect. 113 (1), 17 - 24 10.1289/ehp.7301
2004 (2)
- Luckenbach, T., Corsi, I., Epel, D. (2004):
Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels
Mar. Environ. Res. 58 (2-5), 215 - 219 10.1016/j.marenvres.2004.03.017 - Smital, T., Luckenbach, T., Sauerborn, R., Hamdoun, A.M., Vega, R.L., Epel, D. (2004):
Emerging contaminants-pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms
Mutat. Res.-Fundam. Mol. Mech. Mutagen. 552 (1-2), 101 - 117 10.1016/j.mrfmmm.2004.06.006
2003 (2)
- Luckenbach, T., Ferling, H., Gernhofer, M., Köhler, H.-R., Negele, R.D., Pfefferle, E., Triebskorn, R. (2003):
Developmental and subcellular effects of chronic exposure to sub-lethal concentrations of ammonia, PAH and PCP mixtures in brown trout (Salmo trutta f. fario L.) early life stages
Aquat. Toxicol. 65 (1), 39 - 54 10.1016/S0166-445X(03)00107-3 - Luckenbach, T., Kilian, M., Triebskorn, R., Oberemm, A. (2003):
Assessment of the developmental success of brown trout (Salmo trutta f. fario L.) embryos in two differently polluted streams in Germany
Hydrobiologia 490 (1-3), 53 - 62 10.1023/A:1023477509925
2001 (1)
- Luckenbach, T., Triebskorn, R., Müller, E., Oberemm, A. (2001):
Toxicity of waters from two streams to early life stages of brown trout (Salmo trutta f. fario L.), tested under semi-field conditions
Chemosphere 45 (4-5), 571 - 579 10.1016/S0045-6535(00)00595-6
1999 (1)
- Luckenbach, T., Kilian, M., Triebskorn, R., Oberemm, A. (1999):
Fish early life stage tests as a tool to assess embryotoxic potentials in small streams
J. Aquat. Ecosys. Stress Recov. 8 (3-4), 355 - 370 10.1023/A:1012976809450