Working Groups


Hightroughput Ecotoxicology - HITEC

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Lead: Dr. Jo Nyffeler
Tel. +49 341 6025 - 1264

jo.nyffeler@ufz.de

  • High-throughput phenotypic profiling ('Cell Painting') with human and non-human cell lines
  • High content imaging assays
  • New Approach Methods (in vitro and in silico) for currently underrepresented taxa (e.g., amphibians, reptiles)

Integrative Toxicology - iTox

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Lead: Dr. Wibke Busch
Tel. +49 341 6025 - 1581

wibke.busch@ufz.de

  • Modes of action and mixture risks of environmental pollutants
  • Data-driven toxicology and effect modelling
  • Time- and concentrations-resolved toxicogenomics in zebrafish embryos

Multiple Stressor Ecology – mStress

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Lead: Dr. Mechthild Schmitt-Jansen
Tel. +49 341 6025 - 1523

mechthild.schmitt-jansen@ufz.de

  • Understanding interactions of chemical and non-chemical stressors including particles
  • Integrating effect-based and field-based assessments of chemical exposure
  • Community ecotoxicology
  • Biofilm ecotoxicology and ecology

Mechanistic Toxicology - mTox

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Lead: Prof. Dr. Tamara Tal
Tel. +49 341 6025 - 1524

tamara.tal@ufz.de

  • Building zebrafish-based new approach methods to predict the developmental neurotoxicity (DNT), adult neurotoxicity (ANT), or neuro-immunomodulatory effects of environmental chemicals
  • Generation of computational tools for the analysis and visualization of automated behavior and high-content imaging data
  • Application of unbiased sequencing, gene editing, and pharmacological administration to explore causal mechanisms by which environmental chemicals alter neurobehavior
  • Understanding chemical-microbiome interactions in the context of the microbiome-gut-brain axis

System-Ecotoxicology - sysTox

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Lead: Prof. Dr. Matthias Liess
Tel. +49 341 6025 - 1578

matthias.liess@ufz.de

  • Analyse the combined effects of toxicants and environmental parameters in ecosystems to develop a mechanistic understanding of ecological processes
  • Quantitatively predict the combined effects of toxicants and environmental stressors
  • Monitor and disentangle the impacts of pesticides and other stressors at the ecosystem level
  • Enhance, streamline and validate the regulatory risk assessment of pesticides
  • Develop and promote One Health-focused management strategies