Our congratulations go to Nadine Sossalla from UBZ, who successfully defended her PhD thesis on 23 September 2021. Nadine – it was a pleasure working with you despite the hundreds of samples you swamped our lab with. You are our truly first high-throughput student. All the best for your postdoc in Norway.
We are now offering experimental theses again.
If you are interested in writing your Bachelor or Master Thesis at the department of Cell Toxicology you can contact Beate Escher or you can express your interest by clicking here.
Did you know that we carry on average 2mg of DDT and transformation products, more than 10mg of PCBs, 6mg of brominated flame retardants and 7mg of the fragrance material galaxolide in our bodies? … and these chemicals are only the tip of the iceberg – the 35 chemicals that we detected in blood, brain, liver and adipose tissue could explain only a very small fraction ft he cocktail effect elicited by mixtures of extracted chemicals.
Our former PhD student Andreas Baumer developed in a series of three papers a method to quantify the mixture effects in diverse human tissues that allowed to us estimate the above-mentioned total body burden. The last of the series is now available open access via
https://www.sciencedirect.com/science/article/pii/S016041202100492X
1. Baumer, A.; Escher, B. I.; Landmann, J.; Ulrich, N., 2020. Direct sample introduction GC-MS/MS for quantification of organic chemicals in mammalian tissues and blood extracted with polymers without clean-up. Anal. Bioanal. Chem. 412, 7295-7305.
https://doi.org/10.1007/s00216-020-02864-6
2. Baumer, A.; Jäsch, S.; Ulrich, N.; Bechmann, I.; Landmann, J.; Escher, B. I., 2021. Kinetics of equilibrium passive sampling of organic chemicals with polymers in diverse mammalian issues. Environ. Sci. Technol. 55, 9097-9108. https://doi.org/10.1021/acs.est.1c01836
3. Baumer, A.; Jäsch, S.; Ulrich, N.; Bechmann, I.; Landmann, J.; Stöver, A.; Escher, B. I., 2021. Chemical mixtures in human post-mortem tissues assessed by a combination of chemical analysis and in vitro bioassays after extraction with silicone. Environ. Internat. 157, 106867. https://doi.org/10.1016/j.envint.2021.106867
