DoCE (Dosing for Controlled Exposure) – ‘Dosing strategies for characterising in vitro dose-responses with increased relevance for in vivo extrapolation’
Three teams have been awarded funding to carry out Phase 1 proof-of-concept studies*. Sponsored by Unilever and Shell, this Two Phase Challenge aims to establish improved methods and approaches to better account for bioavailability in vitro to enable robust QIVIVE.
Congratulations Dr. Luise Henneberger!
If you are interested in writing your Bachelor or Master Thesis at the department of Cell Toxicology, please click here.
We have teamed with Veolia Research and Innovation to investigate the water quality of Parisian drinking water. The low levels of disinfection byproducts were below any level of concern. Mixture toxicity modelling showed volatile DBPs had a minor contribution to effect. We were able to differentiate between effects of micropollutants from source water and effects from formed DPBs.
Hebert A, Felier C, Lecarpentier C, Neale P, Schlichting R
, Thibert S, Escher B
Bioanalytical assessment of adaptive stress responses in drinking water as a tool to differentiate between micropollutants and disinfection by-products. Water Res:revised version submitted October 2018.
Link to https://www.sciencedirect.com/science/article/pii/S004313541731093X