2025 (4)

• Alvarez-Mora, I., Arturi, K., Béen, F., Buchinger, S., El Mais, A.E.R., Gallampois, C., Hahn, M., Hollender, J., Houtman, C., Johann, S., Krauss, M., Lamoree, M., Margalef, M., Massei, R., Brack, W., Muz, M. (2025):
  Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification — is it time for HT-EDA?
  Anal. Bioanal. Chem. 417 , 451 - 472 10.1007/s00216-024-05424-4
• Massei, R. (2025):
  2025_ S-BIAD954_zebrafish_subdataset [Data set]
  Zenodo 10.5281/zenodo.14790777
• Massei, R., Busch, W., Serrano-Solano, B., Bernt, M., Scholz, S., Nicolay, E.K., Bohring, H., Bumberger, J. (2025):
  High-content screening (HCS) workflows for FAIR image data management with OMERO
  Sci. Rep. 15 , art. 16236 10.1038/s41598-025-00720-0
• Michaelis, P., Klüver, N., Aulhorn, S., Bohring, H., Bumberger, J., Haase, K., Kuhnert, T., Küster, E., Krüger, J., Luckenbach, T., Massei, R., Nerlich, L., Petruschke, S., Schnicke, T., Schnurpel, A., Scholz, S., Schweiger, N., Sielaff, D., Busch, W. (2025):
  Leveraging zebrafish embryo phenotypic observations to advance data-driven analyses in toxicology
  Environ. Sci. Technol. 59 (9), 4304 - 4317 10.1021/acs.est.4c11757

2024 (3)

• Grasse, N., Massei, R., Seiwert, B., Scholz, S., Escher, B.I., Reemtsma, T., Fu, Q. (2024):
  Impact of biotransformation on internal concentrations and specificity classification of organic chemicals in the zebrafish embryo (Danio rerio)
  Environ. Sci. Technol. 58 (40), 17898 - 17907 10.1021/acs.est.4c04156
• Hayot, G., Massei, R., Lloyd, G., Keith, N., Diwan, G., Martinez Lopez, R., Barnard, M., Cramer von Clausbruch, C.A., Grasse, N., Smoot, S., Escher, B., Tennessen, J., Tindall, A., Oliver, B., Shaw, J., Scholz, S., Freedman, J., Strähle, U., Colbourne, J., Weiss, C., Dickmeis, T. (2024):
  Systematic acquisition of toxicity data in non- sentient models across animal phylogeny: implications for read- across and estimation of toxicity in humans
  Naunyn-Schmiedebergs Arch. Pharmacol. 397 (Suppl. 1), S17 - S18-69 10.1007/s00210-024-02974-3
• Massei, R. (2024):
  Galaxy Training Data for "Overview of the Galaxy OMERO-suite" [Data set]
  Zenodo 10.5281/zenodo.14205500

2023 (4)

• Carere, M., Lacchetti, I., di Domenico, K., Cristiano, W., Mancini, L., De Felip, E., Ingelido, A.M., Massei, R., Tancioni, L. (2023):
  Fish-kills in the urban stretch of the Tiber river after a flash-storm: Investigative monitoring with effect-based methods, targeted chemical analyses, and fish assemblage examinations
  Water Air Soil Pollut. 234 (3), art. 159 10.1007/s11270-023-06102-4
• Colbourne, J.K., Andrews, E., Barnard, M., Čavoški, A., Chaturvedi, A., Epps, D.J.T., Holden, L., Jones, M.R., Li, X., Mueller, F., Ormanin-Lewandowska, A., Orsini, L., Roberts, R., Weber, R.J.M., Zhou, J., Apic, G., Ignasiak, T., Jankovic, K., Krsmanovic, T., Leoni, B., Asole, G., Guigó, R., Marangio, P., Palumbo, E., Perez-Lluch, S., Wucher, V., Vlot, A.H., Anholt, R., Mackay, T., Escher, B.I., Grasse, N., Huchthausen, J., Massei, R., Reemtsma, T., Scholz, S., Schüürmann, G., Bondesson, M., Cherbas, P., et al. (2023):
  The Precision Toxicology initiative
  Toxicol. Lett. 383 , 33 - 42 10.1016/j.toxlet.2023.05.004
• Grasse, N., Seiwert, B., Massei, R., Scholz, S., Fu, Q., Reemtsma, T. (2023):
  Uptake and biotransformation of the tire rubber-derived contaminants 6-PPD and 6-PPD quinone in the zebrafish embryo (Danio rerio)
  Environ. Sci. Technol. 57 (41), 15598 - 15607 10.1021/acs.est.3c02819
• Massei, R., Brack, W., Seidensticker, S., Hollert, H., Muz, M., Schulze, T., Krauss, M., Küster, E. (2023):
  Neurotoxicity in complex environmental mixtures—a case-study at River Danube in Novi Sad (Serbia) using zebrafish embryos
  Environ. Sci. Pollut. Res. 30 (42), 96138 - 96146 10.1007/s11356-023-29186-1

2022 (2)

• Morales, D.A., Massei, R., Schulze, T., Krauss, M., Brack, W., De Aragão Umbuzeiro, G. (2022):
  Mutagenicity of the Danube River: The contribution of liquid phase and particulate suspended matter
  Environ. Mol. Mutagen. 63 (3), 162 - 168 10.1002/em.22478
• Shuliakevich, A., Muz, M., Oehlmann, J., Nagengast, L., Schröder, K., Wolf, Y., Brückner, I., Massei, R., Brack, W., Hollert, H., Schiwy, S. (2022):
  Assessing the genotoxic potential of freshwater sediments after extensive rain events – Lessons learned from a case study in an effluent-dominated river in Germany
  Water Res. 209 , art. 117921 10.1016/j.watres.2021.117921

2021 (3)

• Carere, M., Antoccia, A., Buschini, A., Frenzilli, G., Marcon, F., Andreoli, C., Gorbi, G., Suppa, A., Montalbano, S., Prota, V., De Battistis, F., Guidi, P., Bernardeschi, M., Palumbo, M., Scarcelli, V., Colasanti, M., D'Ezio, V., Persichini, T., Scalici, M., Sgura, A., Spani, F., Udroiu, I., Valenzuela, M., Lacchetti, I., di Domenico, K., Cristiano, W., Marra, V., Ingelido, A.M., Iacovella, N., De Felip, E., Massei, R., Mancini, L. (2021):
  An integrated approach for chemical water quality assessment of an urban river stretch through Effect-Based Methods and emerging pollutants analysis with a focus on genotoxicity
  J. Environ. Manage. 300 , art. 113549 10.1016/j.jenvman.2021.113549
• Ogungbemi, A.O., Massei, R., Altenburger, R., Scholz, S., Küster, E. (2021):
  Assessing combined effects for mixtures of similar and dissimilar acting neuroactive substances on zebrafish embryo movement
  Toxics 9 (5), art. 104 10.3390/toxics9050104
• Ogungbemi, A.O., Teixido, E., Massei, R., Scholz, S., Küster, E. (2021):
  Automated measurement of the spontaneous tail coiling of zebrafish embryos as a sensitive behavior endpoint using a workflow in KNIME
  MethodsX 8 , art. 101330 10.1016/j.mex.2021.101330

2020 (3)

• Kandie, F.J., Krauss, M., Beckers, L.-M., Massei, R., Fillinger, U., Becker, J., Liess, M., Torto, B., Brack, W. (2020):
  Occurrence and risk assessment of organic micropollutants in freshwater systems within the Lake Victoria South Basin, Kenya
  Sci. Total Environ. 714 , art. 136748 10.1016/j.scitotenv.2020.136748
• Kandie, F.J., Krauss, M., Massei, R., Ganatra, A.A., Fillinger, U., Becker, J.M., Liess, M., Torto, B., Brack, W. (2020):
  Multi-compartment chemical characterization and risk assessment of chemicals of emerging concern in freshwater systems of western Kenya
  Environ. Sci. Eur. 32 , art. 115 10.1186/s12302-020-00392-9
• Ogungbemi, A.O., Teixido, E., Massei, R., Scholz, S., Küster, E. (2020):
  Optimization of the spontaneous tail coiling test for fast assessment of neurotoxic effects in the zebrafish embryo using an automated workflow in KNIME®
  Neurotoxicol. Teratol. 81 , art. 106918 10.1016/j.ntt.2020.106918

2019 (1)

• Massei, R., Hollert, H., Krauss, M., von Tümpling, W., Weidauer, C., Haglund, P., Küster, E., Gallampois, C., Tysklind, M., Brack, W. (2019):
  Toxicity and neurotoxicity profiling of contaminated sediments from Gulf of Bothnia (Sweden): a multi‑endpoint assay with zebrafish embryos
  Environ. Sci. Eur. 31 , art. 8 10.1186/s12302-019-0188-y

2018 (4)

• Legradi, J.B., Di Paolo, C., Kraak, M.H.S., van der Geest, H.G., Schymanski, E.L., Williams, A.J., Dingemans, M.M.L., Massei, R., Brack, W., Cousin, X., Begout, M.-L., van der Oost, R., Carion, A., Suarez‑Ulloa, V., Silvestre, F., Escher, B.I., Engwall, M., Nilén, G., Keiter, S.H., Pollet, D., Waldmann, P., Kienle, C., Werner, I., Haigis, A.-C., Knapen, D., Vergauwen, L., Spehr, M., Schulz, W., Busch, W., Leuthold, D., Scholz, S., vom Berg, C.M., Basu, N., Murphy, C.A., Lampert, A., Kuckelkorn, J., Grummt, T., Hollert, H. (2018):
  An ecotoxicological view on neurotoxicity assessment
  Environ. Sci. Eur. 30 , art. 46 10.1186/s12302-018-0173-x
• Massei, R., Busch, W., Wolschke, H., Schinkel, L., Bitsch, M., Schulze, T., Krauss, M., Brack, W. (2018):
  Screening of pesticide and biocide patterns as risk drivers in sediments of major European river mouths: ubiquitous or river basin-specific contamination?
  Environ. Sci. Technol. 52 (4), 2251 - 2260 10.1021/acs.est.7b04355
• Massei, R., Byers, H., Beckers, L.-M., Prothmann, J., Brack, W., Schulze, T., Krauss, M. (2018):
  A sediment extraction and cleanup method for wide-scope multitarget screening by liquid chromatography–high-resolution mass spectrometry
  Anal. Bioanal. Chem. 410 (1), 177 - 188 10.1007/s00216-017-0708-9
• Wolschke, H., Sühring, R., Massei, R., Tang, J., Ebinghaus, R. (2018):
  Regional variations of organophosphorus flame retardants - Fingerprint of large river basin estuaries/deltas in Europe compared with China
  Environ. Pollut. 236 , 391 - 395 10.1016/j.envpol.2018.01.061

2017 (3)

• Inostroza, P.A., Massei, R., Wild, R., Krauss, M., Brack, W. (2017):
  Chemical activity and distribution of emerging pollutants: Insights from a multi-compartment analysis of a freshwater system
  Environ. Pollut. 231 (Part 1), 339 - 347 10.1016/j.envpol.2017.08.015
• Kurth, D., Lips, S., Massei, R., Krauss, M., Luckenbach, T., Schulze, T., Brack, W. (2017):
  The impact of chemosensitisation on bioaccumulation and sediment toxicity
  Chemosphere 186 , 652 - 659 10.1016/j.chemosphere.2017.08.019
• Välitalo, P., Massei, R., Heiskanen, I., Behnisch, P., Brack, W., Tindall, A.J., Du Pasquier, D., Küster, E., Mikola, A., Schulze, T., Sillanpää, M. (2017):
  Effect-based assessment of toxicity removal during wastewater treatment
  Water Res. 126 , 153 - 163 10.1016/j.watres.2017.09.014

2015 (2)

• Klüver, N., König, M., Ortmann, J., Massei, R., Paschke, A., Kühne, R., Scholz, S. (2015):
  Fish embryo toxicity test: Identification of compounds with weak toxicity and analysis of behavioral effects to improve prediction of acute toxicity for neurotoxic compounds
  Environ. Sci. Technol. 49 (11), 7002 - 7011 10.1021/acs.est.5b01910
• Massei, R., Vogs, C., Renner, P., Altenburger, R., Scholz, S. (2015):
  Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects
  Aquat. Toxicol. 166 , 36 - 41 10.1016/j.aquatox.2015.06.011