Dr. Riccardo Massei
Address:
Permoserstr. 15
04318 Leipzig
Germany
Building: 6.1
Room: 703
Phone: +49 341 6025 1512
Dr. Riccardo Massei
Research Interests
- Application of the fish embryo acute toxicity test (FET) with zebrafish in ecotoxicology and human toxicology. In particular, understanding the effect of chemicals on the phenotype and motor behavior of Danio rerio embryos
- Identification of harmful pollutants in aquatic ecosystems using a combination of bioassays (i.e. FET with zebrafish) and chemical analysis (liquid and gas chromatography coupled with high resolution mass spectroscopy).
- Development of novel analytical techniques for the characterization of toxic effect in different environmental matrixes (i.e. water and sediments). Prioritization of hazardous chemicals using effect data extracted from toxicity databases (i.e. EPA ECOTOX Database, Tox21)
- Application of multivariate statistical methods to analyze complex toxicological/chemical data and improve the exploration of toxicity databases.
Curriculum Vitae
Since 07/2021
Postdoctoral researcher, Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research – UFZ, Leipzig
03/2020 - 03/2021
Postdoctoral researcher, Department of Veterinary Sciences, Universiteit Antwerp, Belgium
10/2017 - 02/2020
Postdoctoral researcher, Department of Effect Directed Analysis, Helmholtz Centre for Environmental Research – UFZ, Leipzig
09/2018
Doctoral degree in Natural Sciences
Graduation Thesis: “Novel analytical tools for the toxicological and chemical characterization of aquatic sediments: the incidence of pesticide mixtures and neuroactive chemicals in EU-river basin”
06/2013 - 09/2018
Doctoral Student, RWTH Aachen, Institute for Environmental Research and Department of Effect Directed Analysis, Helmholtz Centre for Environmental Research – UFZ, Leipzig
05/2013
Master's degree in “Molecular Biology”
Graduation Thesis: “Different sensitivity for Azinphos methyl in embryonic stages the zebrafish (Danio rerio): the role of toxicokinetic and stage-specific susceptibility”
03/2012 - 11/2012
Research assistant, Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research – UFZ, Leipzig
03/2011
Bachelor’s degree in “Biology”
Graduation Thesis: “Effects of florfenicol on the detoxification response of Rainbow trout”
05/2010 - 09/2011
Research assistant, Department of Cellular and Environmental Biology, University of Perugia, Italy
Awards/Grants/other Activities
- Young Scientist Awards (YSA) in SETAC 2016 (Nantes, France) for the Poster: “Detection of acetylcholinesterase inhibitors in water samples from Novi Sad (Serbia) using effect-directed analysis and Danio rerio embryos”
- Organizer and chair in the session “Fish model species in human and environmental toxicology” since 2017 (SETAC Europe)
- Active member of the working groups “Bioassays and biomarkers in water quality monitoring” and “Effect-directed analysis for hazardous pollutants identification” in the NORMAN network
Publications
Index:
You could use our publication index for further requests.
2023 (4)
- Carere, M., Lacchetti, I., di Domenico, K., Cristiano, W., Mancini, L., De Felip, E., Ingelido, A.M., Massei, R., Tancioni, L. (2023):
Fish-kills in the urban stretch of the Tiber river after a flash-storm: Investigative monitoring with effect-based methods, targeted chemical analyses, and fish assemblage examinations
Water Air Soil Pollut. 234 (3), art. 159 10.1007/s11270-023-06102-4 - Colbourne, J.K., Andrews, E., Barnard, M., Čavoški, A., Chaturvedi, A., Epps, D.J.T., Holden, L., Jones, M.R., Li, X., Mueller, F., Ormanin-Lewandowska, A., Orsini, L., Roberts, R., Weber, R.J.M., Zhou, J., Apic, G., Ignasiak, T., Jankovic, K., Krsmanovic, T., Leoni, B., Asole, G., Guigó, R., Marangio, P., Palumbo, E., Perez-Lluch, S., Wucher, V., Vlot, A.H., Anholt, R., Mackay, T., Escher, B.I., Grasse, N., Huchthausen, J., Massei, R., Reemtsma, T., Scholz, S., Schüürmann, G., Bondesson, M., Cherbas, P., et al. (2023):
The Precision Toxicology initiative
Toxicol. Lett. 383 , 33 - 42 10.1016/j.toxlet.2023.05.004 - Grasse, N., Seiwert, B., Massei, R., Scholz, S., Fu, Q., Reemtsma, T. (2023):
Uptake and biotransformation of the tire rubber-derived contaminants 6-PPD and 6-PPD quinone in the zebrafish embryo (Danio rerio)
Environ. Sci. Technol. 57 (41), 15598 - 15607 10.1021/acs.est.3c02819 - Massei, R., Brack, W., Seidensticker, S., Hollert, H., Muz, M., Schulze, T., Krauss, M., Küster, E. (2023):
Neurotoxicity in complex environmental mixtures—a case-study at River Danube in Novi Sad (Serbia) using zebrafish embryos
Environ. Sci. Pollut. Res. 30 (42), 96138 - 96146 10.1007/s11356-023-29186-1
2022 (2)
- Morales, D.A., Massei, R., Schulze, T., Krauss, M., Brack, W., De Aragão Umbuzeiro, G. (2022):
Mutagenicity of the Danube River: The contribution of liquid phase and particulate suspended matter
Environ. Mol. Mutagen. 63 (3), 162 - 168 10.1002/em.22478 - Shuliakevich, A., Muz, M., Oehlmann, J., Nagengast, L., Schröder, K., Wolf, Y., Brückner, I., Massei, R., Brack, W., Hollert, H., Schiwy, S. (2022):
Assessing the genotoxic potential of freshwater sediments after extensive rain events – Lessons learned from a case study in an effluent-dominated river in Germany
Water Res. 209 , art. 117921 10.1016/j.watres.2021.117921
2021 (3)
- Carere, M., Antoccia, A., Buschini, A., Frenzilli, G., Marcon, F., Andreoli, C., Gorbi, G., Suppa, A., Montalbano, S., Prota, V., De Battistis, F., Guidi, P., Bernardeschi, M., Palumbo, M., Scarcelli, V., Colasanti, M., D'Ezio, V., Persichini, T., Scalici, M., Sgura, A., Spani, F., Udroiu, I., Valenzuela, M., Lacchetti, I., di Domenico, K., Cristiano, W., Marra, V., Ingelido, A.M., Iacovella, N., De Felip, E., Massei, R., Mancini, L. (2021):
An integrated approach for chemical water quality assessment of an urban river stretch through Effect-Based Methods and emerging pollutants analysis with a focus on genotoxicity
J. Environ. Manage. 300 , art. 113549 10.1016/j.jenvman.2021.113549 - Ogungbemi, A.O., Massei, R., Altenburger, R., Scholz, S., Küster, E. (2021):
Assessing combined effects for mixtures of similar and dissimilar acting neuroactive substances on zebrafish embryo movement
Toxics 9 (5), art. 104 10.3390/toxics9050104 - Ogungbemi, A.O., Teixido, E., Massei, R., Scholz, S., Küster, E. (2021):
Automated measurement of the spontaneous tail coiling of zebrafish embryos as a sensitive behavior endpoint using a workflow in KNIME
MethodsX 8 , art. 101330 10.1016/j.mex.2021.101330
2020 (3)
- Kandie, F.J., Krauss, M., Beckers, L.-M., Massei, R., Fillinger, U., Becker, J., Liess, M., Torto, B., Brack, W. (2020):
Occurrence and risk assessment of organic micropollutants in freshwater systems within the Lake Victoria South Basin, Kenya
Sci. Total Environ. 714 , art. 136748 10.1016/j.scitotenv.2020.136748 - Kandie, F.J., Krauss, M., Massei, R., Ganatra, A.A., Fillinger, U., Becker, J.M., Liess, M., Torto, B., Brack, W. (2020):
Multi-compartment chemical characterization and risk assessment of chemicals of emerging concern in freshwater systems of western Kenya
Environ. Sci. Eur. 32 , art. 115 10.1186/s12302-020-00392-9 - Ogungbemi, A.O., Teixido, E., Massei, R., Scholz, S., Küster, E. (2020):
Optimization of the spontaneous tail coiling test for fast assessment of neurotoxic effects in the zebrafish embryo using an automated workflow in KNIME®
Neurotoxicol. Teratol. 81 , art. 106918 10.1016/j.ntt.2020.106918
2019 (1)
- Massei, R., Hollert, H., Krauss, M., von Tümpling, W., Weidauer, C., Haglund, P., Küster, E., Gallampois, C., Tysklind, M., Brack, W. (2019):
Toxicity and neurotoxicity profiling of contaminated sediments from Gulf of Bothnia (Sweden): a multi‑endpoint assay with zebrafish embryos
Environ. Sci. Eur. 31 , art. 8 10.1186/s12302-019-0188-y
2018 (4)
- Legradi, J.B., Di Paolo, C., Kraak, M.H.S., van der Geest, H.G., Schymanski, E.L., Williams, A.J., Dingemans, M.M.L., Massei, R., Brack, W., Cousin, X., Begout, M.-L., van der Oost, R., Carion, A., Suarez‑Ulloa, V., Silvestre, F., Escher, B.I., Engwall, M., Nilén, G., Keiter, S.H., Pollet, D., Waldmann, P., Kienle, C., Werner, I., Haigis, A.-C., Knapen, D., Vergauwen, L., Spehr, M., Schulz, W., Busch, W., Leuthold, D., Scholz, S., vom Berg, C.M., Basu, N., Murphy, C.A., Lampert, A., Kuckelkorn, J., Grummt, T., Hollert, H. (2018):
An ecotoxicological view on neurotoxicity assessment
Environ. Sci. Eur. 30 , art. 46 10.1186/s12302-018-0173-x - Massei, R., Busch, W., Wolschke, H., Schinkel, L., Bitsch, M., Schulze, T., Krauss, M., Brack, W. (2018):
Screening of pesticide and biocide patterns as risk drivers in sediments of major European river mouths: ubiquitous or river basin-specific contamination?
Environ. Sci. Technol. 52 (4), 2251 - 2260 10.1021/acs.est.7b04355 - Massei, R., Byers, H., Beckers, L.-M., Prothmann, J., Brack, W., Schulze, T., Krauss, M. (2018):
A sediment extraction and cleanup method for wide-scope multitarget screening by liquid chromatography–high-resolution mass spectrometry
Anal. Bioanal. Chem. 410 (1), 177 - 188 10.1007/s00216-017-0708-9 - Wolschke, H., Sühring, R., Massei, R., Tang, J., Ebinghaus, R. (2018):
Regional variations of organophosphorus flame retardants - Fingerprint of large river basin estuaries/deltas in Europe compared with China
Environ. Pollut. 236 , 391 - 395 10.1016/j.envpol.2018.01.061
2017 (3)
- Inostroza, P.A., Massei, R., Wild, R., Krauss, M., Brack, W. (2017):
Chemical activity and distribution of emerging pollutants: Insights from a multi-compartment analysis of a freshwater system
Environ. Pollut. 231 (Part 1), 339 - 347 10.1016/j.envpol.2017.08.015 - Kurth, D., Lips, S., Massei, R., Krauss, M., Luckenbach, T., Schulze, T., Brack, W. (2017):
The impact of chemosensitisation on bioaccumulation and sediment toxicity
Chemosphere 186 , 652 - 659 10.1016/j.chemosphere.2017.08.019 - Välitalo, P., Massei, R., Heiskanen, I., Behnisch, P., Brack, W., Tindall, A.J., Du Pasquier, D., Küster, E., Mikola, A., Schulze, T., Sillanpää, M. (2017):
Effect-based assessment of toxicity removal during wastewater treatment
Water Res. 126 , 153 - 163 10.1016/j.watres.2017.09.014
2015 (2)
- Klüver, N., König, M., Ortmann, J., Massei, R., Paschke, A., Kühne, R., Scholz, S. (2015):
Fish embryo toxicity test: Identification of compounds with weak toxicity and analysis of behavioral effects to improve prediction of acute toxicity for neurotoxic compounds
Environ. Sci. Technol. 49 (11), 7002 - 7011 10.1021/acs.est.5b01910 - Massei, R., Vogs, C., Renner, P., Altenburger, R., Scholz, S. (2015):
Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects
Aquat. Toxicol. 166 , 36 - 41 10.1016/j.aquatox.2015.06.011