Publication Details |
| Reference Category | Journals |
| DOI / URL | link |
| Title (Primary) | Interactions of ginkgolides A and B with a recombinant human prion protein |
| Author | Georgieva, D.; Redecke, L.; von Bergen, M.; Genov, N.; Betzel, C. |
| Journal | Protein and Peptide Letters |
| Year | 2010 |
| Department | PROTEOM |
| Volume | 17 |
| Issue | 3 |
| Page From | 399 |
| Page To | 404 |
| Language | englisch |
| Keywords | Three-dimensional structure; structural transformation; ginkgolide; prion protein; protein misfolding |
| Abstract | In the presence of ginkgolides A and B a recombinant human prion protein (90-231) is more susceptible to proteolysis, which is characteristic for the non-infective form of prion proteins and more thermostable than in the absence of ginkgolides. Probably, ginkgolides exert a neuroprotective effect through a rearrangement of the prion structure. |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=9989 |
| Georgieva, D., Redecke, L., von Bergen, M., Genov, N., Betzel, C. (2010): Interactions of ginkgolides A and B with a recombinant human prion protein Protein Pept. Lett. 17 (3), 399 - 404 |
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