Publication Details |
Category | Text Publication |
Reference Category | Journals |
DOI | 10.1016/S0045-6535(97)00340-8 |
Title (Primary) | Toxicity testing with Vibrio fischeri: A comparison between the long term (24 h) and the short term (30 min) bioassay |
Author | Backhaus, T.; Froehner, K.; Altenburger, R.
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Source Titel | Chemosphere |
Year | 1997 |
Department | OEC; BIOTOX; COE |
Volume | 35 |
Issue | 12 |
Page From | 2925 |
Page To | 2938 |
Language | englisch |
Abstract |
The acute bioluminescence inhibition assay using the marine bacterium Vihrio fischeri as the test organism is a widely used short term toxicity test. This paper compares the standard 30 minutes test with a 24 h assay using the same organism and the same test parameter. For that purpose concentration-response relationships were determined for a set of selected substances, reflecting different modes and mechanisms of action. The results indicate a severe blind spot of the acute biotest: The toxicity of certain specifically acting chemicals is drastically underestimated here, while the chronic biotest gives a more reliable estimate of the toxicity of these substances. |
Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=9149 |
Backhaus, T., Froehner, K., Altenburger, R., Grimme, L.H. (1997): Toxicity testing with Vibrio fischeri: A comparison between the long term (24 h) and the short term (30 min) bioassay Chemosphere 35 (12), 2925 - 2938 10.1016/S0045-6535(97)00340-8 |