Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1016/j.vaccine.2008.01.038 |
| Title (Primary) | High potency vaccines induce protection against heterologous challenge with foot-and-mouth disease virus |
| Author | Brehm, K.E.; Kumar, N.; Thulke, H.-H.
; Haas, B. |
| Source Titel | Vaccine |
| Year | 2008 |
| Department | OESA |
| Volume | 26 |
| Issue | 13 |
| Page From | 1681 |
| Page To | 1687 |
| Language | englisch |
| Keywords | Foot-and-mouth disease virus; Protection by vaccines; Serology |
| Abstract | In a series of three homologous and eight heterologous challenge experiments, it was shown that high potency vaccines against foot-and-mouth disease (FMD) serotype A can induce protection even against heterologous challenge infection with viruses that give low r-values with the vaccine strains. The challenge virus specific neutralizing antibody response on the day of challenge (21 days post vaccination) generally correlated with protection. |
| Brehm, K.E., Kumar, N., Thulke, H.-H., Haas, B. (2008): High potency vaccines induce protection against heterologous challenge with foot-and-mouth disease virus Vaccine 26 (13), 1681 - 1687 10.1016/j.vaccine.2008.01.038 |
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