Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.vaccine.2008.01.038
Title (Primary) High potency vaccines induce protection against heterologous challenge with foot-and-mouth disease virus
Author Brehm, K.E.; Kumar, N.; Thulke, H.-H. ORCID logo ; Haas, B.
Source Titel Vaccine
Year 2008
Department OESA
Volume 26
Issue 13
Page From 1681
Page To 1687
Language englisch
Keywords Foot-and-mouth disease virus; Protection by vaccines; Serology
Abstract In a series of three homologous and eight heterologous challenge experiments, it was shown that high potency vaccines against foot-and-mouth disease (FMD) serotype A can induce protection even against heterologous challenge infection with viruses that give low r-values with the vaccine strains. The challenge virus specific neutralizing antibody response on the day of challenge (21 days post vaccination) generally correlated with protection.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=840
Brehm, K.E., Kumar, N., Thulke, H.-H., Haas, B. (2008):
High potency vaccines induce protection against heterologous challenge with foot-and-mouth disease virus
Vaccine 26 (13), 1681 - 1687 10.1016/j.vaccine.2008.01.038