Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/S0925-4439(00)00038-7
Title (Primary) Structure of tau protein and assembly into paired helical filaments
Author Friedhoff, P.; von Bergen, M.; Mandelkow, E.-M.; Mandelkow, E.
Source Titel Biochimica et Biophysica Acta-Molecular Basis of Disease
Year 2000
Department PROTEOM
Volume 1502
Issue 1
Page From 122
Page To 132
Language englisch
Keywords Alzheimer's disease; Paired helical filament; Tau protein; Self-assembly; Nucleation
Abstract Over the past few years the systematic investigation of paired helical filament assembly from tau protein in vitro has become feasible. We review our current understanding of the structure and conformations of tau protein and how this affects tau's assembly into the pathological paired helical filaments in Alzheimer's disease.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=7140
Friedhoff, P., von Bergen, M., Mandelkow, E.-M., Mandelkow, E. (2000):
Structure of tau protein and assembly into paired helical filaments
Biochim. Biophys. Acta-Mol. Basis Dis. 1502 (1), 122 - 132 10.1016/S0925-4439(00)00038-7