Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1016/S0925-4439(00)00038-7 |
| Title (Primary) | Structure of tau protein and assembly into paired helical filaments |
| Author | Friedhoff, P.; von Bergen, M.; Mandelkow, E.-M.; Mandelkow, E. |
| Source Titel | Biochimica et Biophysica Acta-Molecular Basis of Disease |
| Year | 2000 |
| Department | PROTEOM |
| Volume | 1502 |
| Issue | 1 |
| Page From | 122 |
| Page To | 132 |
| Language | englisch |
| Keywords | Alzheimer's disease; Paired helical filament; Tau protein; Self-assembly; Nucleation |
| Abstract | Over the past few years the systematic investigation of paired helical filament assembly from tau protein in vitro has become feasible. We review our current understanding of the structure and conformations of tau protein and how this affects tau's assembly into the pathological paired helical filaments in Alzheimer's disease. |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=7140 |
| Friedhoff, P., von Bergen, M., Mandelkow, E.-M., Mandelkow, E. (2000): Structure of tau protein and assembly into paired helical filaments Biochim. Biophys. Acta-Mol. Basis Dis. 1502 (1), 122 - 132 10.1016/S0925-4439(00)00038-7 |
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