Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.jaci.2008.09.052
Title (Primary) Increased asthma and respiratory symptoms in children exposed to petrochemical pollution
Author Wichmann, F.A.; Müller, A.; Busi, L.E.; Cianni, N.; Massolo, L.; Schlink, U. ORCID logo ; Porta, A.; Sly, P.D.
Source Titel Journal of Allergy and Clinical Immunology
Year 2009
Volume 123
Issue 3
Page From 632
Page To 638
Language englisch
Keywords Air pollution; asthma; lung function testing; particulate matter; volatile organic compounds
Abstract Background: Epidemiologic studies show statistical associations between levels of air pollutants and respiratory outcomes.Objective: We sought to determine the effects of exposure to petrochemical pollution on the respiratory health of children.Methods: Children aged 6 to 12 years living close to the petrochemical plants in La Plata, Argentina (n = 282), were compared with those living in a region with exposure to heavy traffic (n = 270) or in 2 relatively nonpolluted areas (n = 639). Parents answered a validated questionnaire providing health and demographic data. A random sample (n = 181) had lung function measured. Particulate matter and outdoor and indoor volatile organic compound levels were measured during 4-week study periods and reported as overall means for each study area.Results: Children living near the petrochemical plant had more asthma (24.8% vs 10.1% to 11.5%), more asthma exacerbations (6.7 vs 2.9-3.6 per year), more respiratory symptoms (current wheeze, dyspnea, nocturnal cough, and rhinitis), and lower lung function (>13% decrease in FEV1 percent predicted) than those living in other regions. Length of residence in the area was a significant risk factor, but age, sex, body mass index, proximity to busy roads and other nonpetrochemical industries, length of breast-feeding, and socioeconomic and demographic characteristics of children or their families were not.Conclusion: Exposure to particulate matter and volatile organic compounds arising from petrochemical plants but not from high traffic density was associated ith worse respiratory health in children.
Persistent UFZ Identifier
Wichmann, F.A., Müller, A., Busi, L.E., Cianni, N., Massolo, L., Schlink, U., Porta, A., Sly, P.D. (2009):
Increased asthma and respiratory symptoms in children exposed to petrochemical pollution
J. Allergy Clin. Immunol. 123 (3), 632 - 638 10.1016/j.jaci.2008.09.052