Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1007/s00253-026-13798-x |
Licence  |
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| Title (Primary) | Testing the biodegradability of difficult compounds: a future challenge for the OECD/ISO standardization |
| Author | Strotmann, U.; Heipieper, H.J.
; Eberlein, C.
; Mayer, P.; Birch, H.; Gartiser, S.; Pagga, U.; Daturpalli, S.; Battagliarin, G.; McDonough, K.; Thouand, G. |
| Source Titel | Applied Microbiology and Biotechnology |
| Year | 2026 |
| Department | MEB |
| Volume | 110 |
| Issue | 1 |
| Page From | art. 122 |
| Language | englisch |
| Topic | T7 Bioeconomy |
| Supplements | Supplement 1 |
| Keywords | Chemicals; Biodegradation; OECD/ISO standardized tests; UVCBs; Hydrophobic compounds; Polymers; Microbial inocula |
| Abstract | For a period exceeding five decades, industrial and scientific
communities, in conjunction with regulators, have utilized a
complexified, standardized system (e.g., OECD, Organisation for Economic
Co-operation and Development; ISO, International Organization for
Standardization; ASTM, American Society for Testing and Materials; CEN,
Comité Européen de Normalisation) for the estimation of biodegradability
of organic compounds. This system has been adopted in numerous
countries worldwide and has also been integrated into European
legislation (REACH, registration, authorisation, and restriction of
chemicals). In recent years, a number of deficiencies have been
identified in the standardized biodegradation test systems. This
comprehensive review sets out the fields in which improvements are
necessary to set up the next generation of reliable, standardized
biodegradation tests. The main focus of the review is the challenges and
modifications needed to test difficult-to-test compounds such as
volatile, hydrophobic compounds, UVCBs (unknown or variable composition,
complex reaction products or biological materials), water-soluble
polymers, and plastics. Recent advances in the characterization of
inocula for biodegradation tests are also addressed, which offer a
valuable opportunity to enhance the reliability and reproducibility of
biodegradation assays. Moreover, the potential for predicting
biodegradation in the environment is a subject that is discussed in this
text. |
| Strotmann, U., Heipieper, H.J., Eberlein, C., Mayer, P., Birch, H., Gartiser, S., Pagga, U., Daturpalli, S., Battagliarin, G., McDonough, K., Thouand, G. (2026): Testing the biodegradability of difficult compounds: a future challenge for the OECD/ISO standardization Appl. Microbiol. Biotechnol. 110 (1), art. 122 10.1007/s00253-026-13798-x |
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