Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.1016/j.jwpe.2025.108780 |
| Title (Primary) | Photocatalysis reaction of a mixture of ten pharmaceutical active compounds: transformation products generated under the major degradation pathways |
| Author | Hernández-Tenorio, R.; Hernández-Ramírez, A.; Moeder, M.; Guzmán-Mar, J.L.; Hinojosa-Reyes, L. |
| Source Titel | Journal of Water Process Engineering |
| Year | 2025 |
| Department | EAC |
| Volume | 78 |
| Page From | art. 108780 |
| Language | englisch |
| Topic | T9 Healthy Planet |
| Supplements | Supplement 1 |
| Keywords | High resolution mass spectrometry; Hydroxylation; Fragmentation; Intramolecular reaction |
| Abstract | Pharmaceutical active compounds (PhACs) are prevalent in wastewater and aquatic environments globally. Discharges from urban, hospital, and industrial effluents contribute to high concentrations and variability of PhACs and their transformation products (TPs) in municipal sewage systems, ultimately reaching wastewater treatment plants (WWTPs). This study investigates the photocatalytic degradation of ten PhACs, both individually and in a mixture, under simulated sunlight and zinc oxide modified with 10 % fluoride (ZnO-F10) material. Compared with ZnO bare, the doped fluoride catalyst (ZnO-F10) reduced the recombination rate of e−/h+ pairs, allowing the generation of more significant amounts of HO• radicals, and thereby improving the photocatalytic activity under simulated solar radiation. Monitoring and elucidation of major TPs were performed using UPLC-MS/MS and high-resolution mass spectrometry (HR-MS). Degradation percentages ranged from 12% to 100%, depending on the substance, when each PhAC was degraded individually. Three primary degradation pathways were identified: 1) hydroxylation reactions via HO• radical attack, generating hydroxylated intermediates; 2) fragmentation reactions through energy absorption and HO• attack, resulting in oxidized compounds via photolysis, hydrolysis, decarboxylation, demethylation, deamination, and dealkylation; and 3) intramolecular redox reactions on the catalyst surface, forming heterocyclic structures. These pathways refer to the formation of TP from hospitals and drug manufacturing industries during wastewater treatment under advanced oxidation processes (AOPs). Implementing analytical methods to identify the main TPs of PhACs is crucial for effective environmental monitoring. |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=31890 |
| Hernández-Tenorio, R., Hernández-Ramírez, A., Moeder, M., Guzmán-Mar, J.L., Hinojosa-Reyes, L. (2025): Photocatalysis reaction of a mixture of ten pharmaceutical active compounds: transformation products generated under the major degradation pathways J. Water Process Eng. 78 , art. 108780 10.1016/j.jwpe.2025.108780 |
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