Publication Details

Category Text Publication
Reference Category Journals
DOI 10.1016/j.biortech.2025.133577
Title (Primary) Microalgae-mediated shaping of bacterial communities enhances antibiotic removal and antibiotic resistance control
Author Lin, S.; Pan, M.; Ma, Y.; Cheng, Z.; Lyu, T.; Dong, R.; Ruan, R.; Liu, S.
Source Titel Bioresource Technology
Year 2026
Department MIBITECH
Volume 441
Page From art. 133577
Language englisch
Topic T7 Bioeconomy
Keywords Microalgae-bacterial consortia; Sulfadiazine degradation; Extracellular polymeric substances; Antibiotic resistance; Antibiotic resistance genes transfer
Abstract The microalgae-bacteria symbiosis sludge (MBSS) system offers a promising strategy for efficient wastewater treatment and nutrients upcycling. However, maintaining stable and effective performance facing antibiotic stress remains a significant challenge. This study explored the regulation strategy of microbial succession towards sulfadiazine (SDZ)-containing wastewater remediation while controlling antibiotic resistance genes (ARGs) spread in MBSS system. The MBSS achieved efficient SDZ removal of up to 99.8%, with an optimal microalgae-to-activated sludge inoculation ratio of 1:3. However, the highest nutrient upcycling efficiencies (33.7% for nitrogen and 98.6% for phosphorus) were observed at an inoculation ratio of 1:1. Metagenomics analysis revealed that genera Chlorella and Micractinium of Chlorophyta were strongly positively correlated with SDZ removal. Moreover, microalgae inoculation significantly modulated the microbial community structure, promoting the dominance of genera Rhodanobacter and Dokdonella in MBSS. This microbial succession could potentially facilitate bacterial co-degradation of SDZ and contribute to a substantially reduced level of ARGs (with the relative abundance of sul1 and sul2 decreasing to 22.9% post-treatment). Overall, the strategy of regulating microalgae inoculation in the MBSS significantly enhanced antibiotic removal and nutrient recovery while controlling the proliferation and spread of ARGs by directing microbial community succession.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=31689
Lin, S., Pan, M., Ma, Y., Cheng, Z., Lyu, T., Dong, R., Ruan, R., Liu, S. (2026):
Microalgae-mediated shaping of bacterial communities enhances antibiotic removal and antibiotic resistance control
Bioresour. Technol. 441 , art. 133577 10.1016/j.biortech.2025.133577